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Locally Rooted, Globally Respected www.ugm.ac.id
Locally Rooted, Globally Respected www.ugm.ac.id

... macrophages, and augments cytotoxicity of lymphocytes for target ...
Thiazide and Thiazide
Thiazide and Thiazide

... •is a thiazide like drug • It is primarily used to treat congestive hear failure and HTN • Metolazone indirectly decreases the amount of water reabsorbed into the bloodstream by the kidney, so that blood volume decreases and urine volume increases. This lowers blood pressure and prevents excess flui ...
Cyclodextrins in peptide and protein delivery
Cyclodextrins in peptide and protein delivery

... T. Irie, K. Uekama / Advanced Drug Delivery Reviews 36 (1999) 101 – 123 ...
Learn How to Manage Your PNH
Learn How to Manage Your PNH

... ongoing hemolysis. However, in some patients, the body breaks down drugs faster. In rare cases, hemolysis can start up again even if you are taking Soliris on your regular schedule. This is called “breakthrough hemolysis.” If you are not experiencing the full benefits of your Soliris therapy, your d ...
Clinical Medicine Reviews in Therapeutics Intermittent Asthma
Clinical Medicine Reviews in Therapeutics Intermittent Asthma

... ­administered to children 3–6 months of age33 yielded systemic exposures similar to those observed in ­children aged 6–24  months.34 The respective ­maximum plasma ­concentrations were 561.1  ng/ml and 514.4  ng/ml.33,34 The pharmacokinetic profile of the 6–24  month group on a single 4  mg dose of ...
Neurochemical Enhancement of Conscious Error Awareness
Neurochemical Enhancement of Conscious Error Awareness

... arose if the same word was presented on two consecutive trials (“repeat no-go”) and the second if the word and its font color matched (“color no-go”) rather than the typical word and color incongruency (for examples, see Fig. 1). By having two competing types of response inhibition, we aimed to vary ...
RETROVIRAL DISEASE
RETROVIRAL DISEASE

... persistent viral replication. Therefore, antiretroviral treatment has been shown to improve CD4 cell count, reduce viral replication, reduce the frequency of opportunistic infection, improve quality of life and hence, prolong life expectancy of HIV infected patients. Through collaboration with other ...
Clenbuterol - National Drug Strategy
Clenbuterol - National Drug Strategy

... effect' of increasing muscle mass and body weight by enhancing muscle protein synthesis in rodents. However, no human studies are available on whether clenbuterol can increase strength or power. Body builders and athletes most often utilise clenbuterol as a 'fat burner' to 'define' muscles (i.e. for ...
Exelon Patch
Exelon Patch

... receiving concurrent nonsteroidal anti-inflammatory drugs (NSAIDs). Clinical studies of rivastigmine have shown no significant increase, relative to placebo, in the incidence of either peptic ulcer disease or gastrointestinal bleeding. Use with Anesthesia Rivastigmine, as a cholinesterase inhibitor, ...
An evaluation of the anti-inflammatory activity auranofin
An evaluation of the anti-inflammatory activity auranofin

... (RA). Although the drug has been successful in treating the symptoms of RA, many patients discontinue its use due to severe toxicity over long periods of continued treatment. Since the introduction of auranofin in 1985 there has been no new clinically approved gold drug. Drug discovery research is d ...
Endocrine disrupting substances
Endocrine disrupting substances

... that are released into the environment, with special emphasis on Swedish conditions. Following the evaluation of existing knowledge, recommendations for future research are given. In the present report we are primarily focusing on chemicals that have the potential of interfering, as agonists or anta ...
AHA Scientific Statement
AHA Scientific Statement

... Figure 1. The effect of multiple risk factors on the extent of atherosclerosis in the aorta and coronary arteries in children and young adults. Values shown are the percentages of the intimal surface covered with fibrous plaques in subjects with 0, 1, 2, and 3 or 4 risk factors. Reproduced from Bere ...
Brief of the American Public Health Association, et al: MARCUS
Brief of the American Public Health Association, et al: MARCUS

... The experiences of patients and the observations of their physicians are in accord with the conclusions of medical researchers, and recent governmentsponsored commissions that have concluded that marijuana has therapeutic properties not replicated by other currently available medications. In fact, ...
MAGNESIUM SULFATE IN 5% DEXTROSE
MAGNESIUM SULFATE IN 5% DEXTROSE

... Sulfate in 5% Dextrose Injection, USP should be used during pregnancy only if clearly needed. If this drug is used during pregnancy the woman should be apprised of the potential harm to the fetus. When administered by continuous IV infusion (especially for more than 24 hours preceding delivery) to c ...
the PDF
the PDF

... this new method of treatment immediately (Becker et al., 1997; Becker et al., 1995; Dralle et al., 1985; Gianino et al., 1998; Ochs, 1993; Ochs et al., 1989; Rawlins, 1998). Quantitative measurements by Leisen et al. (2003) showed that intrathecal administration of doses up to 600 mg resulted in loc ...
Overcoming the Bell-Shaped Dose-Response of
Overcoming the Bell-Shaped Dose-Response of

... Marinol (Dronabinol) and Cesamet, have been approved for use in cancer-related anorexia-cachexia syndrome as well as for nausea and vomiting [3]. But a major disadvantage of Cannabis phytomedicine is its psychoactive effects due to the presence of 9-Tetrahydrocannabinol (THC). Recently, a science-ba ...
Escitalopram For The Treatment anxiety Disorders
Escitalopram For The Treatment anxiety Disorders

... behavioral studies also showed that R-citalopram exerts effects counteracting those of escitalopram (antidepressant- and anxiolytic-like effects). The reason for these differences between the two enantiomers might also concern the secondary molecular targets at which citalopram acts, but with affini ...
Linköping University Post Print Blood-brain barrier penetration of the
Linköping University Post Print Blood-brain barrier penetration of the

... According to in vitro studies the enantiomers of venlafaxine display different degrees of serotonin and noradrenaline reuptake inhibition. Therefore, clarification of the enantiomeric drug distribution between serum and brain is highly warranted. To elucidate if P-glycoprotein (P-gp) in a stereosele ...
enzyme induction and inhibition
enzyme induction and inhibition

... drug for assessing drug metabolism in man. It fulfils the above requirements for the ideal marker drug with almost complete hepatic metabolism, less than 10% plasma protein binding and less than 5% excreted unchanged in the urine. Its single compartment kinetics together with its relative ease of me ...
Looking for the Edge– Dietary Supplements
Looking for the Edge– Dietary Supplements

... Energy Drinks ...
Reynolds-Psych-Panels-11-20-12
Reynolds-Psych-Panels-11-20-12

... Consider olanzapine. SULT4A1-1 positive patients have been shown to demonstrate enhanced treatment efficacy and reduced hospitalization risk when treated with olanzapine compared to both SULT4A1-1 negative patients treated with olanzapine and SULT4A1-1 positive patients treated with risperidone. CYP ...
7 Antifungal therapy c h a P t e r
7 Antifungal therapy c h a P t e r

... the next 60 years landmarks in the field included discoveries and characterization of dimorphic fungi, recognition of fungi as human pathogens capable of causing systemic diseases, the development of laboratory diagnostic tests and classification systems, and initial epidemiologic and ecologic inves ...
Metabolic Characteristics of Oxcarbazepine (®Trileptal
Metabolic Characteristics of Oxcarbazepine (®Trileptal

... (cf. Fig. 2). Cytosolic aldo-keto reductases are reported to be non-inducible, and glucuronyltransferases do not appear to be very responsive to induction in general. The latter enzyme system is particularly important for oxcarbazepine, because it controls the elimination of the active metabolite MH ...
St John`s wort (Hypericum perforatum L.): a review of its
St John`s wort (Hypericum perforatum L.): a review of its

... containing 0.3 % hypericin and 3.8 % hyperforin was found to inhibit 10 % ethanol intake in alcohol-preferring rats ; however, the inhibitory effect was not modified by pre-treatment with either intraperitoneal rimcazole (a sigma receptor antagonist) or intracerebroventricular 5,7-dihydroxytryptamin ...
Vasopressin Axis in Shock States
Vasopressin Axis in Shock States

... rapidly increase extracellular water content, it should be used with caution in patients with chronic nephritis, CHF, asthma, epilepsy ...
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Bilastine



Bilastine (trade name Bilaxten) is a second generation antihistamine drug for the treatment of allergic rhinoconjunctivitis and urticaria (hives).It exerts its effect as a selective histamine H1 receptor antagonist, and has a effectiveness similar to cetirizine, fexofenadine and desloratadine. It was developed in Spain by FAES Farma.Bilastine is approved in the European Union for the symptomatic treatment of allergic rhinoconjunctivitis and urticaria, but it is not approved by the U.S. Food and Drug Administration for any use in the United States. Bilastine meets the current European Academy of Allergy and Clinical Immunology (EAACI) and Allergic Rhinitis and its Impact of Asthma (ARIA) criteria for medication used in the treatment of allergic rhinitis.Bilastine has been effective in the treatment of ocular symptoms and diseases of allergies, including rhinoconjuctivitis. Additionally, bilastine has been shown to improve quality of life, and all nasal and ocular symptoms related to allergic rhinitis.
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