A treasure of medicinal herb - Anacyclus pyrethrum A review
... stimulus. Electro-convulsive shock (50mA for 0.2 sec) was delivered through corneal electrode to induce HLTE phase in mice. The electrical stimulus was applied using a stimulator apparatus for five groups of six each (Gautam, 2011). Group I served as control (vehicle treated) (i.p.); Group II served ...
... stimulus. Electro-convulsive shock (50mA for 0.2 sec) was delivered through corneal electrode to induce HLTE phase in mice. The electrical stimulus was applied using a stimulator apparatus for five groups of six each (Gautam, 2011). Group I served as control (vehicle treated) (i.p.); Group II served ...
Chemotherapy Regimens Clinical Coding Standards and Guidance
... this refers to the cost of the drug, the transportation, storage and pharmacy preparation resource at a site. The majority of regimens also have a code for delivery (administration) of the chemotherapy drug(s). Some hospitals deliver regimens as inpatients and some deliver them as day cases or outpa ...
... this refers to the cost of the drug, the transportation, storage and pharmacy preparation resource at a site. The majority of regimens also have a code for delivery (administration) of the chemotherapy drug(s). Some hospitals deliver regimens as inpatients and some deliver them as day cases or outpa ...
EASL Recommendations on Treatment of Hepatitis C 2015
... and daclatasvir, with or without ribavirin, has also been widely used in patients with advanced liver disease throughout Europe, based on the results of a Phase II study in patients infected with genotype 1 reporting SVR rates between 95% and 100% [14]. This combination was well tolerated over the c ...
... and daclatasvir, with or without ribavirin, has also been widely used in patients with advanced liver disease throughout Europe, based on the results of a Phase II study in patients infected with genotype 1 reporting SVR rates between 95% and 100% [14]. This combination was well tolerated over the c ...
Pharmacogenetics of Neonatal Opioid Toxicity
... in pharmacodynamic parameters, such as transport across the blood–brain barrier and polymorphism at the μ-opioid receptors, can contribute to variability in morphine analgesia. However, the influence of these polymorphisms in neonates is not yet clear. Following the publication of the first symptoma ...
... in pharmacodynamic parameters, such as transport across the blood–brain barrier and polymorphism at the μ-opioid receptors, can contribute to variability in morphine analgesia. However, the influence of these polymorphisms in neonates is not yet clear. Following the publication of the first symptoma ...
Modelling of tolerance and rebound in normal and
... potential risks can be minimized. In this thesis nicotinic acid (NiAc)-induced changes in non-esterified fatty acids (NEFA) were used as a tool to investigate key determinants of tolerance and rebound in normal Sprague Dawley and in obese Zucker rats, a disease model of dyslipidaemia. The aim of the ...
... potential risks can be minimized. In this thesis nicotinic acid (NiAc)-induced changes in non-esterified fatty acids (NEFA) were used as a tool to investigate key determinants of tolerance and rebound in normal Sprague Dawley and in obese Zucker rats, a disease model of dyslipidaemia. The aim of the ...
Phosphodiesterase 5 inhibitors: are they cardioprotective?
... ventricular cardiomyocytes completely independent from vascular responses or haemodynamic effects. Further experiments using isolated cardiomyocytes suggested that cardioprotection induced by sildenafil was dependent upon protein kinase G activated by cGMP, and involves phosphorylation of Erk 1/2 an ...
... ventricular cardiomyocytes completely independent from vascular responses or haemodynamic effects. Further experiments using isolated cardiomyocytes suggested that cardioprotection induced by sildenafil was dependent upon protein kinase G activated by cGMP, and involves phosphorylation of Erk 1/2 an ...
THE CONTRIBUTION OF FETAL METABOLISM TO THE
... enzymes have been identified in humans, with many parallel homologs found among primates (Mackenzie et al., 1997). Although a certain degree of specificity exists, individual isoforms bind a diverse range of endogenous and exogenous compounds. Furthermore, each UGT is uniquely regulated in response ...
... enzymes have been identified in humans, with many parallel homologs found among primates (Mackenzie et al., 1997). Although a certain degree of specificity exists, individual isoforms bind a diverse range of endogenous and exogenous compounds. Furthermore, each UGT is uniquely regulated in response ...
1 EC-NAPROSYN (naproxen delayed
... Naproxen is a nonsteroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic properties. The sodium salt of naproxen has been developed as a more rapidly absorbed formulation of naproxen for use as an analgesic. The mechanism of action of the naproxen anion, like that of other NSAIDs, is ...
... Naproxen is a nonsteroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic properties. The sodium salt of naproxen has been developed as a more rapidly absorbed formulation of naproxen for use as an analgesic. The mechanism of action of the naproxen anion, like that of other NSAIDs, is ...
Airway Mgt of the Critically Ill Patient
... attempts. Also, critical care physicians cannot always count on having the most highly skilled members of the nursing and respiratory therapy staff on duty to assist with difficult intubations. All of these factors warrant the standardization of the approaches used for emergency intubation in the IC ...
... attempts. Also, critical care physicians cannot always count on having the most highly skilled members of the nursing and respiratory therapy staff on duty to assist with difficult intubations. All of these factors warrant the standardization of the approaches used for emergency intubation in the IC ...
DOXOrubicin vials - Sagent Pharmaceuticals
... Doxorubicin HCl can result in myocardial damage, including acute left ventricular failure. The risk of cardiomyopathy is generally proportional to the cumulative exposure. Include prior doses of other anthracyclines or anthracenediones in calculations of total cumulative dosage for doxorubicin HCl. ...
... Doxorubicin HCl can result in myocardial damage, including acute left ventricular failure. The risk of cardiomyopathy is generally proportional to the cumulative exposure. Include prior doses of other anthracyclines or anthracenediones in calculations of total cumulative dosage for doxorubicin HCl. ...
A Position Paper - American College of Physicians
... Marijuana has been smoked for its medicinal properties for centuries. It was in the U.S. Pharmacopoeia until 1942 when it was removed because federal legislation made the drug illegal (2). The Controlled Substance Act of 1970 placed marijuana in the Schedule I category along with other substances de ...
... Marijuana has been smoked for its medicinal properties for centuries. It was in the U.S. Pharmacopoeia until 1942 when it was removed because federal legislation made the drug illegal (2). The Controlled Substance Act of 1970 placed marijuana in the Schedule I category along with other substances de ...
Albuterol Sulfate Inhalation Solution 0.083%
... sulfate should not be exposed. Persons with cardiovascular disorders (including coronary artery disease, heart rhythm abnormalities and high blood pressure), seizure disorders (epilepsy) hyperthyroidism, or diabetes may experience worsening of symptoms from occupational exposure. Also, persons using ...
... sulfate should not be exposed. Persons with cardiovascular disorders (including coronary artery disease, heart rhythm abnormalities and high blood pressure), seizure disorders (epilepsy) hyperthyroidism, or diabetes may experience worsening of symptoms from occupational exposure. Also, persons using ...
Survey study of challenging experiences after ingesting psilocybin
... standard error of the mean) were used to characterize the responses to questions and the subscale scores of the questionnaires. Pearson correlations were used to analyze the associations among participant ratings of the degree of difficulty of the challenging experience, the duration of the challeng ...
... standard error of the mean) were used to characterize the responses to questions and the subscale scores of the questionnaires. Pearson correlations were used to analyze the associations among participant ratings of the degree of difficulty of the challenging experience, the duration of the challeng ...
WHO Drug Information - World Health Organization
... information puts greater pressure on regulators to react professionally and with transparency in a minimum of time. In spite of many positive developments in the Global regulatory arena it is worrying that the gaps among regulatory systems ...
... information puts greater pressure on regulators to react professionally and with transparency in a minimum of time. In spite of many positive developments in the Global regulatory arena it is worrying that the gaps among regulatory systems ...
Effects of grapefruit juice on the pharmacokinetics of selected
... A serendipitous finding about 10 years ago in a clinical drug study, when grapefruit juice was used to mask the taste of ethanol, led to the discovery of a grapefruit juice-felodipine interaction. Felodipine is a dihydropyridine calcium-channel antagonist used for the treatment of hypertension. Simu ...
... A serendipitous finding about 10 years ago in a clinical drug study, when grapefruit juice was used to mask the taste of ethanol, led to the discovery of a grapefruit juice-felodipine interaction. Felodipine is a dihydropyridine calcium-channel antagonist used for the treatment of hypertension. Simu ...
the neurobiology of nicotine addiction: clinical and public policy
... The duration of relief from withdrawal that is provided by smoking a single cigarette shrinks with repeated exposure to nicotine. A youth who was able to keep withdrawal in check by smoking one cigarette every few days finds that, over time, he or she must smoke at more and more frequent intervals t ...
... The duration of relief from withdrawal that is provided by smoking a single cigarette shrinks with repeated exposure to nicotine. A youth who was able to keep withdrawal in check by smoking one cigarette every few days finds that, over time, he or she must smoke at more and more frequent intervals t ...
“Robo-Tripping”: Dextromethorphan Abuse and its Anesthetic
... dextromethorphan abuse, suggesting that clinically significant opioid tolerance did not occur. Finally, whether acute dextromethorphan intoxication is capable of reducing opioid requirements during and after surgery similar to subanesthetic doses of ketamine also remains to be established. Managemen ...
... dextromethorphan abuse, suggesting that clinically significant opioid tolerance did not occur. Finally, whether acute dextromethorphan intoxication is capable of reducing opioid requirements during and after surgery similar to subanesthetic doses of ketamine also remains to be established. Managemen ...
Single Exposure of Human Oral Mucosa Fibroblasts to
... The lip vermillion constitutes a transition tissue, between oral mucosa and skin, where oral mucosal cells from epithelial and connective tissue compartments are exposed to ultraviolet (UV) sunlight. Fibroblasts are abundant resident cells of the connective tissue which are key regulators of extrace ...
... The lip vermillion constitutes a transition tissue, between oral mucosa and skin, where oral mucosal cells from epithelial and connective tissue compartments are exposed to ultraviolet (UV) sunlight. Fibroblasts are abundant resident cells of the connective tissue which are key regulators of extrace ...
Antiretroviral Interactions With Transplant Medications
... Case report of an HIVpositive liver transplant recipient who received cyclosporine and raltegravir posttransplant. Cyclosporine concentrations were measured regularly and remained therapeutic. Pre- and post dose raltegravir levels were measured at weeks 4 and 8, and were comparable with published da ...
... Case report of an HIVpositive liver transplant recipient who received cyclosporine and raltegravir posttransplant. Cyclosporine concentrations were measured regularly and remained therapeutic. Pre- and post dose raltegravir levels were measured at weeks 4 and 8, and were comparable with published da ...
EC-NAPROSYN (naproxen delayed-release tablets) NAPROSYN (naproxen tablets)
... Five hundred and fifty-three patients received EC-NAPROSYN during longterm open-label trials (mean length of treatment was 159 days). The rates for clinically-diagnosed peptic ulcers and GI bleeds were similar to what has been historically reported for long-term NSAID use. Geriatric Patients The hep ...
... Five hundred and fifty-three patients received EC-NAPROSYN during longterm open-label trials (mean length of treatment was 159 days). The rates for clinically-diagnosed peptic ulcers and GI bleeds were similar to what has been historically reported for long-term NSAID use. Geriatric Patients The hep ...
Effects of Valerian Extract on the Sleep
... alerian, an herbalproduct consisting oftheroot of Sakamoto et al.［8］reported that a30 ethanol extract Valeriana officinalis, is used extensively as a of valerian root signifi cantly prolonged hexobarbitaltraditional medicine for the treatment of insomnia and induced sleep and decreased spontaneous ambu ...
... alerian, an herbalproduct consisting oftheroot of Sakamoto et al.［8］reported that a30 ethanol extract Valeriana officinalis, is used extensively as a of valerian root signifi cantly prolonged hexobarbitaltraditional medicine for the treatment of insomnia and induced sleep and decreased spontaneous ambu ...
S F R SAMHSA
... levels. It is highly bound to plasma protein and is inactivated by enzymatic transformation via N-dealkylation and conjugation (Elkader & Sproule, 2005). Buprenorphine is widely distributed, with peak plasma concentration occurring at about 90 minutes and a half-life of 4 to 5 hours. It is metaboliz ...
... levels. It is highly bound to plasma protein and is inactivated by enzymatic transformation via N-dealkylation and conjugation (Elkader & Sproule, 2005). Buprenorphine is widely distributed, with peak plasma concentration occurring at about 90 minutes and a half-life of 4 to 5 hours. It is metaboliz ...
Coccidiosis or Coccidiasis?
... • Coccidiosis remains today the most frequently diagnosed subclinical disease of broiler chickens. • The estimated global cost to broiler producers for prevention and control programs is $300 M. • The estimated global economic losses on broiler performance are at least $3 billion. • Therefore, it is ...
... • Coccidiosis remains today the most frequently diagnosed subclinical disease of broiler chickens. • The estimated global cost to broiler producers for prevention and control programs is $300 M. • The estimated global economic losses on broiler performance are at least $3 billion. • Therefore, it is ...
TACROLIMUS AND THERAPY OF HUMAN AUTOIMMUNE
... Tacrolimus appears to be of benefit in these conditions. Z4 One patient with scleritis who was refractory to CsA has responded to tacrolimus. Preliminary data appear to show that steroid use will still be required in these conditions. although at a reduced dose. Mochizuki and his colleagues (Kurume ...
... Tacrolimus appears to be of benefit in these conditions. Z4 One patient with scleritis who was refractory to CsA has responded to tacrolimus. Preliminary data appear to show that steroid use will still be required in these conditions. although at a reduced dose. Mochizuki and his colleagues (Kurume ...
Bilastine
Bilastine (trade name Bilaxten) is a second generation antihistamine drug for the treatment of allergic rhinoconjunctivitis and urticaria (hives).It exerts its effect as a selective histamine H1 receptor antagonist, and has a effectiveness similar to cetirizine, fexofenadine and desloratadine. It was developed in Spain by FAES Farma.Bilastine is approved in the European Union for the symptomatic treatment of allergic rhinoconjunctivitis and urticaria, but it is not approved by the U.S. Food and Drug Administration for any use in the United States. Bilastine meets the current European Academy of Allergy and Clinical Immunology (EAACI) and Allergic Rhinitis and its Impact of Asthma (ARIA) criteria for medication used in the treatment of allergic rhinitis.Bilastine has been effective in the treatment of ocular symptoms and diseases of allergies, including rhinoconjuctivitis. Additionally, bilastine has been shown to improve quality of life, and all nasal and ocular symptoms related to allergic rhinitis.