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IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)

Chemical or crazy?
Chemical or crazy?

... • A measure of drug activity expressed in terms of the amount required to produce an effect of given intensity. A highly potent drug evokes a larger response at low concentrations. It is proportional to Affinity and ...
Psychostimulants and Cognition: A Continuum of Behavioral and
Psychostimulants and Cognition: A Continuum of Behavioral and

... that psychostimulants should include drugs that may not produce hyperlocomotion (e.g., caffeine and modafinil). We refer to the more narrow class of psychostimulants that also produce significant hyperlocomotion (e.g., cocaine and amphetamine) as psychomotor stimulants. Moreover, even psychomotor st ...
MATERNITY UNIT GUIDELINE: Inhibition of preterm labour SCOPE
MATERNITY UNIT GUIDELINE: Inhibition of preterm labour SCOPE

... A diagnosis of PTL is made when regular uterine contractions, at least 3 in 30 minutes (i.e. 1:10), are present, accompanied by effacement and/or dilatation of the cervix. Contractions alone without cervical changes are not definitive of labour. If PTL is suspected the obstetrician on call should be ...
CREB - testing
CREB - testing

... CREB is critical for the manifestation of the physical signs of opiate withdrawal, but its role is not known ...
Presentation - Chronice Myeloid Leukemia
Presentation - Chronice Myeloid Leukemia

... • These patients form a heterogeneous group • Can try any of the remaining TKIs • Consider SCT in eligible patients. • Ponatinib is likely to be more efficient than any other TKI, but there are no comparative studies ...
A Beef Producers Guide for Judicious Use of Antimicrobials in Cattle
A Beef Producers Guide for Judicious Use of Antimicrobials in Cattle

... should be used to evaluate therapeutic regimens and always follow proper withdrawal times. 12. Follow Label Directions: Follow label instructions and never use antibiotics other than as labeled without a valid veterinary prescription. ...
Canaccord Genuity Annual Growth Conference
Canaccord Genuity Annual Growth Conference

... market potential of our product candidates, the impact of competitive products and pricing, new product development, uncertainties related to the regulatory approval process and other risks detailed from time to time in the Company’s ongoing quarterly filings and annual reports. Forward-looking stat ...
Appropriate use of NSAIDs: Considering cardiovascular risk in the
Appropriate use of NSAIDs: Considering cardiovascular risk in the

... Permanente integrated managed care organization, investigators looked for an NSAIDassociated risk of acute MI or sudden cardiac death (SCD) in 1.4 million patients taking selective and nonselective NSAIDs over a 3-year period.13 Analysis was carried out on a total of 8,143 patients who had serious c ...
ANTI-INFLAMMATORY EFFECT OF THE SERRATIOPEPTIDASE
ANTI-INFLAMMATORY EFFECT OF THE SERRATIOPEPTIDASE

... kind. Though there is some evidence that proteins may be absorbed orally, it is applicable to only few proteins in ‘extremely low’ amounts (12-13). This amount may not sufficient to produce efficacy of a ‘protein drug.’ In addition to this there is hardly any evidence present for the oral absorption ...
IN THE MATTER OF * BEFORE THE MARYLAND MELISSA MILLER
IN THE MATTER OF * BEFORE THE MARYLAND MELISSA MILLER

... hydromorphone at 0815 and 1200. There is no docmnentation of administration of the 1620 dose that was withdrawn. There is no record that a dose was withdrawn prior to the 0815 administration ...
Cardiac Drugs - medicallyoung
Cardiac Drugs - medicallyoung

... ◦ Binds to plasma proteins, blood cells, and endothelial cells ◦ Administered intravenously ◦ Weight-based protocol ◦ Administrated subcutaneoulsy ◦ aPTT , PT, INR, platelet count, hemoglobin level and hematocrit ◦ Bleeding potential complication ◦ Thrombocytopenia ...
Local anaesthetics
Local anaesthetics

Tablets CEFTIN for Oral Suspension (cefuroxime axetil tablets)
Tablets CEFTIN for Oral Suspension (cefuroxime axetil tablets)

... Food Effect on Pharmacokinetics: Absorption of the tablet is greater when taken after food (absolute bioavailability of CEFTIN Tablets increases from 37% to 52%). Despite this difference in absorption, the clinical and bacteriologic responses of patients were independent of food intake at the time o ...
SCHIZOPHRENIA2001
SCHIZOPHRENIA2001

PART III: CONSUMER INFORMATION Pr ADALAT® XL® Nifedipine
PART III: CONSUMER INFORMATION Pr ADALAT® XL® Nifedipine

... Your doctor will tell you how much of this medicine to use and how often. Your dose may need to be changed several times in order to find out what works best for you. Follow your doctor's treatment plan exactly so that you reach and maintain your blood pressure targets, and get relief from angina. D ...
ANTI-ALLERGIC, ANTI-INFLAMMATORY AND ANALGESIC ACTIONS OF STEM BARK EXTRACT
ANTI-ALLERGIC, ANTI-INFLAMMATORY AND ANALGESIC ACTIONS OF STEM BARK EXTRACT

Management of Lower Urinary Tract Symptoms (LUTS) in men
Management of Lower Urinary Tract Symptoms (LUTS) in men

... For patients who require a once daily preparation: Darifenacin 7.5 mg- 15 mg od May have fewer CNS side effects ...
Nasal Drug Delivery in EMS
Nasal Drug Delivery in EMS

...  Rectal diazepam (Valium) is unsuccessful at controlling the seizure.  IV attempts in the ED are also unsuccessful.  However, on patient arrival a dose of nasal midazolam (Versed, Dormicum) is given and within 3 minutes of drug delivery the child stops seizing. ...
Phase 1 study to evaluate the feasibility and efficacy
Phase 1 study to evaluate the feasibility and efficacy

... The information contained in this document is the property of the AGMT and therefore is provided to you in confidence for review by you, your staff, an applicable Ethics Committee/Institutional Review Board and regulatory authorities. It is understood that the information will not be disclosed to ot ...
PHARMACEUTICAL ASPECTS OF NICORANDIL   
PHARMACEUTICAL ASPECTS OF NICORANDIL   

Pharmacogenetics and Individualized Drug Therapy
Pharmacogenetics and Individualized Drug Therapy

... polymorphisms to individual differences in drug effects and toxicity is not well understood. Moreover, most studies have focused on the effect of a single polymorphism on drug response. This approach neglects the fact that drug-response phenotype, like most disease phenotypes, is a complex polygenic ...
GHS Medication Therapy Disease Management Program(MTDM)
GHS Medication Therapy Disease Management Program(MTDM)

... SAO medication order (past 45 days) and who had 3 or more SAO medication orders in the past 6 months. Patients with an MUA are those that either have a scanned MUA document, an MUA is indicated in the problem list or a letter was printed and sent. MUA and TOX % means percent of compliance. Added the ...
Major Bleeding and Hemorrhagic Stroke With Direct Oral
Major Bleeding and Hemorrhagic Stroke With Direct Oral

... were thus included in the final analyses (Fig 1).15-23 The conventional comparator in these studies was warfarin or subcutaneous enoxaparin followed by warfarin. The nine studies included 94,879 patients, 40,230 with normal renal function, 40,681 with eCrCL 50 to 80 mL/min, and 13,996 with eCrCL < 50 ...
united states securities and exchange commission - corporate
united states securities and exchange commission - corporate

... purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the “Exchange Act”), or incorporated by reference in any filing under the Securities Act of 1933, as amended, or the Exchange Act, except as expressly set forth by specific reference in such a filing. Item 8.01 ...
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Bilastine



Bilastine (trade name Bilaxten) is a second generation antihistamine drug for the treatment of allergic rhinoconjunctivitis and urticaria (hives).It exerts its effect as a selective histamine H1 receptor antagonist, and has a effectiveness similar to cetirizine, fexofenadine and desloratadine. It was developed in Spain by FAES Farma.Bilastine is approved in the European Union for the symptomatic treatment of allergic rhinoconjunctivitis and urticaria, but it is not approved by the U.S. Food and Drug Administration for any use in the United States. Bilastine meets the current European Academy of Allergy and Clinical Immunology (EAACI) and Allergic Rhinitis and its Impact of Asthma (ARIA) criteria for medication used in the treatment of allergic rhinitis.Bilastine has been effective in the treatment of ocular symptoms and diseases of allergies, including rhinoconjuctivitis. Additionally, bilastine has been shown to improve quality of life, and all nasal and ocular symptoms related to allergic rhinitis.
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