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Pharmacologic Advances in Canine and Feline Reproduction TOPICAL REVIEW
Pharmacologic Advances in Canine and Feline Reproduction TOPICAL REVIEW

... An estrogen peak approximately 30 days before the onset of estrus is believed to be required to prime the hypothalamuspituitary-ovarian axis, causing release of LH in a pulsating fashion.19,20 Successful induction of fertile estrus in bitches has been accomplished with DES in various doses with or w ...
Neomycin - Australian Pesticides and Veterinary Medicines Authority
Neomycin - Australian Pesticides and Veterinary Medicines Authority

... Longer intervals between dosing (eg once-daily dosing) that provide a drug-free period in which bacteria are not exposed to the drug appear to preserve bactericidal activity of aminoglycosides and reduce the risk of antimicrobial resistance, as well as toxicity (Freeman et al. 1997). Studies in anim ...
Benfluorex and valvular heart disease
Benfluorex and valvular heart disease

... Purpose To evaluate and quantify in diabetic patients treated with benfluorex in France, a fenfluramine-derivated product, a possible increase in risk of valvular heart disease, previously suggested by several published case reports. Methods This was a French comparative cohort study using data from t ...
Pharmacokinetics and dosage adjustment in patients with hepatic
Pharmacokinetics and dosage adjustment in patients with hepatic

... Introduction ...
Clinical Discussion of Special Populations - M
Clinical Discussion of Special Populations - M

... – For a new drug or indication, if there is anticipated or actual use in pregnancy – Usage is expected to be rare, but the consequences of under- or over-dosing are great (e.g., narrow therapeutic ...
Buprenorphine for Treating Opioid-Dependent Pregnant Women: Behavioral Pharmacology in Action
Buprenorphine for Treating Opioid-Dependent Pregnant Women: Behavioral Pharmacology in Action

... • At least 6 studies comparing NAS and other outcomes of infants exposed in utero to methadone vs. buprenorphine • Results of many suggested milder, more limited NAS and other ...
Orthostatic Hypotension and Supine Hypertension in
Orthostatic Hypotension and Supine Hypertension in

... will contain a total of about 200 mg of caffeine and could increase systolic BP by more than 20 mm Hg.14,15 Compressive stockings that ideally go up to the waist can be of great help16 if they are tolerated. Head-of-bed elevation can theoretically increase morning blood volume and decrease orthostat ...
comparative efficacy of combined use of diclofenac with
comparative efficacy of combined use of diclofenac with

... the American College of Physicians recommend using NSAIDs as first-line treatment of acute pain and the use of skeletal muscle relaxants along with them show better effectiveness in management of pain than NSAIDs alone. In the present study we assessed the efficacy of diclofenac and diclofenac+ Thio ...
Walker GJA, Johnstone PW. Interventions for treating
Walker GJA, Johnstone PW. Interventions for treating

... Patients who are first exposed to scabies often do not develop symptoms for several weeks. A well documented case report detailed the spread of scabies in a day care center, in which 21% of the staff and children were eventually infected. More than 570 family members of the children also became symp ...
Nitazoxanide (Alinia)  - Texas Medicaid/CHIP Vendor Drug
Nitazoxanide (Alinia) - Texas Medicaid/CHIP Vendor Drug

... Nitazoxanide is rapidly metabolized to tizoxanide following oral administration. Because tizoxanide is highly bound to plasma proteins (>99.9%), caution should be exercised when dosing nitazoxanide concurrently with other drugs highly protein bound possessing narrow therapeutic indices as competitio ...
EPIPRINUS MALLOTIFORMIS LEAF METHANOLIC EXTRACT  Research Article
EPIPRINUS MALLOTIFORMIS LEAF METHANOLIC EXTRACT Research Article

Therapeutic Drug Monitoring (TDM)
Therapeutic Drug Monitoring (TDM)

... pharmacokinetic parameters such as plasma half-life (t0.5) and apparent volume of distribution (V ) can be calculated. Having derived appropriate pharmacokinetic parameters for a given drug it may then be possible to predict future dose requirements, the effects of changing the dose or the frequency ...
to an editable version.
to an editable version.

...  Sodium should be reduced to < 1500mg/day in normotensive patients to prevent hypertension o 65mmol Na+ or 3.8g NaCl  Up to 17% of hypertension can be attributed to high sodium diets  Effects of Sodium Restriction o Hypertensives  5.1/2.7mmHg drop in BP with an average reduction of 78mmol of sod ...
Addiction (1999) 94(5), 665-674
Addiction (1999) 94(5), 665-674

... Given current concerns about "drug driving" and road traffic accidents, it is also important to know whether methadone impairs the psychomotor skills and speed of reaction time which are central to driving skills. Patients taking other prescribed psychotropics such as benzodiazepines and certain ant ...
sloan_sz_aaem_barcel..
sloan_sz_aaem_barcel..

... There are an estimated 2.5 million patients with epilepsy in the US, based on a prevalence of about 6.6 per 1000 Americans.1 Up to 28% of all epilepsy patients require treatment in Emergency Departments annually.2 In addition to these patients who have an established seizure diagnosis, another 150,0 ...
PIROXICAM PIROXICAM - The Filipino Doctor
PIROXICAM PIROXICAM - The Filipino Doctor

... acute renal failure, which is usually reversible. The occurrence of these interactions should be considered in patients taking piroxicam (Feldene) with a diuretic, an ACE inhibitor or an AIIA. Therefore, the concomitant administration of these drugs should be done with caution, especially in elderly ...
Public Assessment Report Scientific discussion Paroxetine Jubilant
Public Assessment Report Scientific discussion Paroxetine Jubilant

... the similarity could be shown. These results point to the solubility limitations rather than to a formulation effect. In conclusion, the biowaiver for the 10, 20 and 30 mg tablets is considered to be sufficiently justified and can be granted. Bioequivalence studies Design A single-dose, randomised, ...
2016-2017 Targeted Medication Safety Best Practices for Hospitals
2016-2017 Targeted Medication Safety Best Practices for Hospitals

... Oral liquid dosing devices that only display the metric scale should be used. In addition, if patients are taking an oral liquid medication after discharge, supply them with (or provide a prescription for) oral syringes, to enable them to measure oral liquid volumes in mL. ...
Report of the WHO Informal Consultation on the use of Praziquantel
Report of the WHO Informal Consultation on the use of Praziquantel

... Prevention and Control of Schistosomiasis and Soil-transmitted Helminthiasis (8-14 October 2001), the participating experts felt that the current WHO recommendations to avoid using praziquantel during pregnancy and lactation and mebendazole or albendazole in children under two years of age, needed t ...
ROSUVASTATIN CORE SAFETY PROFILE
ROSUVASTATIN CORE SAFETY PROFILE

... Paediatric population Paediatric use should only be carried out by specialists. Children and adolescents 10 to 17 years of age (boys Tanner Stage II and above, and girls who are at least 1 year post-menarche) In children and adolescents with heterozygous familial hypercholesterolaemia the usual star ...
Practicalities in the Use of Obesity Pharmacologic Agents
Practicalities in the Use of Obesity Pharmacologic Agents

... first year of use, but much less so in the second year • Qsymia appears to be more effective than lorcaserin, but ...
PharmaGuide S V How to Use
PharmaGuide S V How to Use

... The user will have to select any one country of his choice. Once a country is selected, the data for all the six countries will be downloaded. Now the data for the selected country will appear. The selection will remain valid, until and unless the user selects another country from the option menu. T ...
Antipsychotics
Antipsychotics

... Dopamine Synapse ...
Cannabinoids in the Treatment of Epilepsy
Cannabinoids in the Treatment of Epilepsy

... seizurelike discharges,15 whereas CB1R agonists eliminate these discharges.16 Conditional knockout mice that lack pyramidal-cell CB1R in their forebrain have more severe and prolonged seizures than wild-type mice in response to kainic acid14,17; in contrast, viral-vector–mediated overexpression of C ...
Colic Pain Management - Hagyard Equine Medical Institute
Colic Pain Management - Hagyard Equine Medical Institute

... excessive. If transport time is expected to be long or the patient’s level of pain is likely to worsen, options for providing additional pain relief during transport should be included in the plan. A dose of morphine (0.1-0.2 mg/kg IV or IM can be administered to augment the level of analgesia. Wit ...
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Bilastine



Bilastine (trade name Bilaxten) is a second generation antihistamine drug for the treatment of allergic rhinoconjunctivitis and urticaria (hives).It exerts its effect as a selective histamine H1 receptor antagonist, and has a effectiveness similar to cetirizine, fexofenadine and desloratadine. It was developed in Spain by FAES Farma.Bilastine is approved in the European Union for the symptomatic treatment of allergic rhinoconjunctivitis and urticaria, but it is not approved by the U.S. Food and Drug Administration for any use in the United States. Bilastine meets the current European Academy of Allergy and Clinical Immunology (EAACI) and Allergic Rhinitis and its Impact of Asthma (ARIA) criteria for medication used in the treatment of allergic rhinitis.Bilastine has been effective in the treatment of ocular symptoms and diseases of allergies, including rhinoconjuctivitis. Additionally, bilastine has been shown to improve quality of life, and all nasal and ocular symptoms related to allergic rhinitis.
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