Nocturnal Penile Tumescence
... double-blind, placebo-controlled crossover study in 12 normal healthy males. Nefazodone increased rapid eye movement (REM) sleep, whereas trazodone and buspirone suppressed REM sleep. The drugs only minimally affected other sleep stages. Trazodone increased total tumescence time by delaying the onse ...
... double-blind, placebo-controlled crossover study in 12 normal healthy males. Nefazodone increased rapid eye movement (REM) sleep, whereas trazodone and buspirone suppressed REM sleep. The drugs only minimally affected other sleep stages. Trazodone increased total tumescence time by delaying the onse ...
British Association for Psychopharmacology consensus statement
... groups and clinical subtypes were specifically covered by individual speakers. Presenters were asked to provide a review of the literature and identification of the standard of evidence in their area, with an emphasis on meta-analyses, systematic reviews and randomized controlled trials (RCTs) where a ...
... groups and clinical subtypes were specifically covered by individual speakers. Presenters were asked to provide a review of the literature and identification of the standard of evidence in their area, with an emphasis on meta-analyses, systematic reviews and randomized controlled trials (RCTs) where a ...
Regulation of tumor necrosis factor
... Another gene that has come into the spotlight more recently for increasing a person’s susceptibility to RA is Protein Tyrosine Phosphatase (PTPN22). The PTPN22 gene encodes a lymphoid-specific phosphatase (Lyp), which then binds to the C-src tyrosine (Csk) kinase. Once this binding happens, T cell r ...
... Another gene that has come into the spotlight more recently for increasing a person’s susceptibility to RA is Protein Tyrosine Phosphatase (PTPN22). The PTPN22 gene encodes a lymphoid-specific phosphatase (Lyp), which then binds to the C-src tyrosine (Csk) kinase. Once this binding happens, T cell r ...
The Science Behind Sacredness of Tulsi
... thousand years without any known adverse effects. There have been number of scientific studies conducted to evaluate the toxic effects of the plant. Bhargava and Singh (20) studied the toxicity to find out the lethal dose of ethanolic extract of Tulsi in adult mice. Approximate LD 50 of Ocimum sanct ...
... thousand years without any known adverse effects. There have been number of scientific studies conducted to evaluate the toxic effects of the plant. Bhargava and Singh (20) studied the toxicity to find out the lethal dose of ethanolic extract of Tulsi in adult mice. Approximate LD 50 of Ocimum sanct ...
The Background and Chemistry ofMDMA
... rats (oral administrations daily in increasing increments of 25 mg/kg per day for 13 days), survivors were sacrificed for tissue and brain pathology studies after a three-week wait. There were blood indicators of damage to both liver and kidney, but histological studies of brain tissue revealed no p ...
... rats (oral administrations daily in increasing increments of 25 mg/kg per day for 13 days), survivors were sacrificed for tissue and brain pathology studies after a three-week wait. There were blood indicators of damage to both liver and kidney, but histological studies of brain tissue revealed no p ...
Inhaled nicotine replacement therapy
... as NRTs (at least in the US) but instead as tobacco products [15]. E-cigarettes are gaining in popularity and may offer some safety benefits over cigarettes in terms of harm reduction due to elimination of exposure to carcinogenic tobacco combustion products [16]. However, much is unknown about the ...
... as NRTs (at least in the US) but instead as tobacco products [15]. E-cigarettes are gaining in popularity and may offer some safety benefits over cigarettes in terms of harm reduction due to elimination of exposure to carcinogenic tobacco combustion products [16]. However, much is unknown about the ...
Highly impulsive rats: modelling an endophenotype to determine the
... that is responsible for maladaptive impulsivity. Thus, animals that exhibit trait impulsivity have provided a useful experimental approach to the investigation of impulsivity. To date, a number of studies have identified particular strains of rodents that demonstrate increased levels of impulsivity ...
... that is responsible for maladaptive impulsivity. Thus, animals that exhibit trait impulsivity have provided a useful experimental approach to the investigation of impulsivity. To date, a number of studies have identified particular strains of rodents that demonstrate increased levels of impulsivity ...
WHO recommendations for the prevention and treatment of
... misoprostol are recommended as alternatives for the prevention of PPH in settings where oxytocin is unavailable. The importance of controlled cord traction (CCT) was revisited because of new evidence. This intervention is now regarded as optional in settings where skilled birth attendants are availa ...
... misoprostol are recommended as alternatives for the prevention of PPH in settings where oxytocin is unavailable. The importance of controlled cord traction (CCT) was revisited because of new evidence. This intervention is now regarded as optional in settings where skilled birth attendants are availa ...
AVAGE ® (tazarotene) Cream 0.1%
... Based on data from animal reproduction studies, retinoid pharmacology, and the potential for systemic absorption, AVAGE Cream may cause fetal harm when administered to a pregnant female and is contraindicated during pregnancy. Safety in pregnant females has not been established. The potential risk t ...
... Based on data from animal reproduction studies, retinoid pharmacology, and the potential for systemic absorption, AVAGE Cream may cause fetal harm when administered to a pregnant female and is contraindicated during pregnancy. Safety in pregnant females has not been established. The potential risk t ...
Manuscript_12122012_revised
... (ChemPrep Inc., FL., USA). The rationale for use of two different EIA kits for serum samples was that 10-fold lower serum volumes could be used for the Phoenix assay and it also had a wider linear concentration range. The Bachem EIA had greater sensitivity at low pM concentrations, which the Phoenix ...
... (ChemPrep Inc., FL., USA). The rationale for use of two different EIA kits for serum samples was that 10-fold lower serum volumes could be used for the Phoenix assay and it also had a wider linear concentration range. The Bachem EIA had greater sensitivity at low pM concentrations, which the Phoenix ...
PA Criteria
... Uncontrolled hypertension. Pts receiving chemotherapy with curative intent. Cancer pts not receiving concomitant myelosuppressive chemotherapy. Pts with myeloid cancer. For all uses: 1) Pretreatment (no erythropoietin treatment in previous month) Hgb is less than 10 g/dL, 2) For reauthorizations (pa ...
... Uncontrolled hypertension. Pts receiving chemotherapy with curative intent. Cancer pts not receiving concomitant myelosuppressive chemotherapy. Pts with myeloid cancer. For all uses: 1) Pretreatment (no erythropoietin treatment in previous month) Hgb is less than 10 g/dL, 2) For reauthorizations (pa ...
Neptune Krill Oil 500 mg
... hexanicotinate was not associated with flushing in clinical trials, even when it was used in dosages as high as 4 grams daily. Vascular Support: A double blind, randomized, placebo-controlled trial was conducted to evaluate the effectiveness of inositol hexanicotinate in relieving peripheral vasospa ...
... hexanicotinate was not associated with flushing in clinical trials, even when it was used in dosages as high as 4 grams daily. Vascular Support: A double blind, randomized, placebo-controlled trial was conducted to evaluate the effectiveness of inositol hexanicotinate in relieving peripheral vasospa ...
Pharmacology of platelet inhibition in humans: implications of the
... aspirin may deliver little or no aspirin to the systemic blood. This was the case, for instance, in healthy volunteers taking 320 mg of compressed aspirin or 800 mg of enteric-coated aspirin. In all instances thromboxane B2 generation in serum was fully inhibited. Platelet cyclooxygenase might there ...
... aspirin may deliver little or no aspirin to the systemic blood. This was the case, for instance, in healthy volunteers taking 320 mg of compressed aspirin or 800 mg of enteric-coated aspirin. In all instances thromboxane B2 generation in serum was fully inhibited. Platelet cyclooxygenase might there ...
Losartan Potassium
... levels have risen to a minor extent in a few losartan potassium-treated patients, but this rarely necessitates treatment withdrawal. The incidence of drug-related adverse events and drug withdrawal using losartan potassium plus hydrochlorothiazide resembled that for losartan potassium alone and for ...
... levels have risen to a minor extent in a few losartan potassium-treated patients, but this rarely necessitates treatment withdrawal. The incidence of drug-related adverse events and drug withdrawal using losartan potassium plus hydrochlorothiazide resembled that for losartan potassium alone and for ...
View PDF - UMass Medical School
... a luciferase expression plasmid and luciferase activity in the liver was assessed by in vivo bioluminescence imaging 2–7 days after injection [62]. Despite improved nuclease stability, no functional difference in luciferase knockdown was observed between modified and unmodified siRNAs. Using hydrody ...
... a luciferase expression plasmid and luciferase activity in the liver was assessed by in vivo bioluminescence imaging 2–7 days after injection [62]. Despite improved nuclease stability, no functional difference in luciferase knockdown was observed between modified and unmodified siRNAs. Using hydrody ...
diazepam interaction on methadone-induced - HAL
... three injections of 1 mL of air into the chamber and the ambient temperature was noted. The spirogram was recorded and stored on a computer with an acquisition data card (PCI-DAS 1000, Dipsi, Chatillon, France) using respiratory acquisition software (Acquis1 Software, CNRS, Gif-sur-Yvette, France) ...
... three injections of 1 mL of air into the chamber and the ambient temperature was noted. The spirogram was recorded and stored on a computer with an acquisition data card (PCI-DAS 1000, Dipsi, Chatillon, France) using respiratory acquisition software (Acquis1 Software, CNRS, Gif-sur-Yvette, France) ...
GUIDELINE FOR STABLE CORONARY ARTERY DISEASE
... The ads showed in this issue are of the sole responsibility of advertisers, as well as the concepts expressed in signed articles are of the sole responsibility of their authors and do not necessarily reflect the views of SBC. ...
... The ads showed in this issue are of the sole responsibility of advertisers, as well as the concepts expressed in signed articles are of the sole responsibility of their authors and do not necessarily reflect the views of SBC. ...
Cytarabine Injection
... considerably reduced risk if therapy is initiated during the second or third trimester. Although normal infants have been delivered to patients treated in all three trimesters of pregnancy, follow-up of such infants would be advisable. Nursing Women It is not known whether this drug is excreted in h ...
... considerably reduced risk if therapy is initiated during the second or third trimester. Although normal infants have been delivered to patients treated in all three trimesters of pregnancy, follow-up of such infants would be advisable. Nursing Women It is not known whether this drug is excreted in h ...
Astragalus membranaceus Monograph
... to the authors, the results suggest Astragalus should be valuable in preventing and treating acute myocarditis caused by coxsackie-B virus.21 In another study by Yang et al, intramuscular injections of Astragalus for 3-4 months in patients with coxsackie-B viral myocarditis resulted in a significant ...
... to the authors, the results suggest Astragalus should be valuable in preventing and treating acute myocarditis caused by coxsackie-B virus.21 In another study by Yang et al, intramuscular injections of Astragalus for 3-4 months in patients with coxsackie-B viral myocarditis resulted in a significant ...
Morphine-induced conditioned place preference and asso
... that progress to death at an earlier age [8-11]. The HIV-1Tg rat displays the characteristics of HIV associated dementia (HAD); it shows impaired spatial learning and memory, reversal learning and the learning of a new strategy compared to control F344 rats [12, 13]. The persistent presence of HIV v ...
... that progress to death at an earlier age [8-11]. The HIV-1Tg rat displays the characteristics of HIV associated dementia (HAD); it shows impaired spatial learning and memory, reversal learning and the learning of a new strategy compared to control F344 rats [12, 13]. The persistent presence of HIV v ...
Genetic polymorphisms and drug interactions modulating
... and associated with a significant number of drug-related deaths (Davis et al., 2003). The long-standing clinical use of oxycodone (Falk, 1917), and lack of sufficient analytical sensitivity to detect active metabolites explain it has bypassed the conventional pharmacological studies assessing its ph ...
... and associated with a significant number of drug-related deaths (Davis et al., 2003). The long-standing clinical use of oxycodone (Falk, 1917), and lack of sufficient analytical sensitivity to detect active metabolites explain it has bypassed the conventional pharmacological studies assessing its ph ...
Advair HFA - GSK Source
... each added to usual asthma therapy, showed an increase in asthma-related deaths in subjects receiving salmeterol. The Salmeterol Multi-center Asthma Research Trial (SMART) was a randomized double-blind trial that enrolled LABA-naive subjects with asthma to assess the safety of salmeterol 42 mcg twic ...
... each added to usual asthma therapy, showed an increase in asthma-related deaths in subjects receiving salmeterol. The Salmeterol Multi-center Asthma Research Trial (SMART) was a randomized double-blind trial that enrolled LABA-naive subjects with asthma to assess the safety of salmeterol 42 mcg twic ...
PDF - Cosmetic Ingredient Review
... nephrotoxicity of maleic acid.18 Male rats fed diets containing 1% or more maleic acid showed growth retardation, increased mortality, and changes in the renal proximal convoluted tubules.19 However, another study using dogs that were fed the same levels that showed no toxicity. The restriction was ...
... nephrotoxicity of maleic acid.18 Male rats fed diets containing 1% or more maleic acid showed growth retardation, increased mortality, and changes in the renal proximal convoluted tubules.19 However, another study using dogs that were fed the same levels that showed no toxicity. The restriction was ...
Discriminative Stimulus Properties of MDMA
... MDMA has been largely overlooked. The broad aims of these experiments were 1) to test the ability of two different doses of MDMA to support drug discrimination learning, and 2) to determine the role of serotonin (5-HT) and dopamine (DA) neurotransmitter systems in producing the discriminative stimul ...
... MDMA has been largely overlooked. The broad aims of these experiments were 1) to test the ability of two different doses of MDMA to support drug discrimination learning, and 2) to determine the role of serotonin (5-HT) and dopamine (DA) neurotransmitter systems in producing the discriminative stimul ...
Bilastine
Bilastine (trade name Bilaxten) is a second generation antihistamine drug for the treatment of allergic rhinoconjunctivitis and urticaria (hives).It exerts its effect as a selective histamine H1 receptor antagonist, and has a effectiveness similar to cetirizine, fexofenadine and desloratadine. It was developed in Spain by FAES Farma.Bilastine is approved in the European Union for the symptomatic treatment of allergic rhinoconjunctivitis and urticaria, but it is not approved by the U.S. Food and Drug Administration for any use in the United States. Bilastine meets the current European Academy of Allergy and Clinical Immunology (EAACI) and Allergic Rhinitis and its Impact of Asthma (ARIA) criteria for medication used in the treatment of allergic rhinitis.Bilastine has been effective in the treatment of ocular symptoms and diseases of allergies, including rhinoconjuctivitis. Additionally, bilastine has been shown to improve quality of life, and all nasal and ocular symptoms related to allergic rhinitis.