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1 - Physical Pharmacy Laboratory
1 - Physical Pharmacy Laboratory

... A solute distributes itself between two immiscible solvents so that the ratio of its concentration in each solvent is equal to the ratio of its solubility in each one ...
FORMULATION AND EVALUATION OF ALCOHOL RESISTANT DOSAGE FORMS OF DICLOFENAC SODIUM
FORMULATION AND EVALUATION OF ALCOHOL RESISTANT DOSAGE FORMS OF DICLOFENAC SODIUM

... formulations to modify oral absorption by matrix pellet. Pelletization [1,2] is a term used to define agglomeration of drug substances in either powder or granule form resulting in the form of semi spherical and spherical agglomerates having good flow properties. Generally, the particle sizes of the ...
Bioburden Control of Non-sterile Drug Substances and Products
Bioburden Control of Non-sterile Drug Substances and Products

... USP Intention • The new USP Informational Chapter <1115>  Bioburden Control of Non‐sterile Drug Substances  and Products was published in the 2nd Supplement  to USP37‐NF32 July 2014. What was the intent of the  USP in publishing this chapter? USP in publishing this chapter?  • In the absence of reg ...
A Review: Stereochemical consideration and eudismic ratio in chiral
A Review: Stereochemical consideration and eudismic ratio in chiral

... popular for the practicing physician. The contributing to a total North American manufacturers are keen to provide the share of $3.98 billion, making up 60% of optically pure drugs to avoid the the total. European and Asian consumption undesirable side effects of the distomer. of enantiomeric fine c ...
Novartis Pharmaceuticals to Pay $390 Million
Novartis Pharmaceuticals to Pay $390 Million

... overload due to blood transfusions. After launching the drug, Novartis marketed Exjade as a treatment for patients with a number of underlying conditions that affect blood cells or bone marrow, including beta-thalassemia, sickle cell disease, and myelodysplastic syndromes. The settlement resolves al ...
“FORMULATION &amp; PROCESS DEVELOPMENT OF AZITHROMYCIN OPHTHALMIC NANOSUSPENSION”  Research Article
“FORMULATION & PROCESS DEVELOPMENT OF AZITHROMYCIN OPHTHALMIC NANOSUSPENSION” Research Article

... conventional ophthalmic suspension such as blurred vision, burning, stinging and irritation upon instillation. The viscosity was increased to provide additional advantage of long duration of action. Method: Solvent diffusion method was used to prepare azithromycin ophthalmic nanosuspension. Result: ...
C  O L
C O L

...  When the dosage forms reach the colon, transit depends on size. Small particles pass through the colon more slowly than the larger units. However, the density and size of larger single, units had no real effect on colonic transit.  It has been shown that pellets move faster than do tablets throug ...
Team Buckeye | OSUCCC - James - James Cancer Center
Team Buckeye | OSUCCC - James - James Cancer Center

... development of highly individualized combination therapies. In infectious diseases genomic and post-genomic approaches suggest that pathways in microbes and host cells can be targeted simultaneously to affect disease progression and elimination of pathogens. This offers the possibility of both reduc ...
rencana program dan kegiatan pembelajaran
rencana program dan kegiatan pembelajaran

... efficacy, safety, and comparative information with other drugs. The cost of a drug, whether it is anew drug or a generic that has been on the formulary for many years, may change frequently andrequires frequent evaluation. Consistent decision making is necessary in the selection of drugsand involves ...
Research Chemicals - KFx Drug Consultancy Initiative
Research Chemicals - KFx Drug Consultancy Initiative

ASHP Guidelines on Surgery and Anesthesi
ASHP Guidelines on Surgery and Anesthesi

... continuation of maintenance medications and discontinuation of unnecessary medications postoperatively. Medication-Use Evaluation. The pharmacist should take a leadership role in the performance of medication-use evaluations by establishing criteria, collecting data, analyzing the data, making recom ...
International Journal for Pharmaceutical Research Scholars (IJPRS)
International Journal for Pharmaceutical Research Scholars (IJPRS)

... tablets must include substances to mask the bitter taste of the active ingredient. This masked active ingredient is then swallowed by the patient's saliva along with the soluble and insoluble excipients3,4. Some drugs are absorbed from the oral cavity, pharynx and esophagus as the saliva passes down ...
Chapter 6: Mesoporous Silica: An Alternative Diffusion Controlled
Chapter 6: Mesoporous Silica: An Alternative Diffusion Controlled

... hormones and vaccines, to mention a few (5,6). The ability to control over the drug delivery can be an important factor especially at times when traditional oral or injectable drug formulations are difficult to distribute. In some cases there might be a need of a slow release of a water soluble drug ...
Melanotan II - Rebound Health
Melanotan II - Rebound Health

PERCUTANEOUS DRUG DELIVERY SYSTEMS FOR IMPROVING ANTIFUNGAL THERAPY EFFECTIVENESS: A REVIEW
PERCUTANEOUS DRUG DELIVERY SYSTEMS FOR IMPROVING ANTIFUNGAL THERAPY EFFECTIVENESS: A REVIEW

... only the ones related with fungi but also with Leishmania parasites that grow in skin layers. Azoles are the most commonly used antifungals in clinical treatment of superficial fungal infections, but their physicochemical properties limit their bioavailability; consequently most of the azoleloaded d ...
ajinomoto acquires althea
ajinomoto acquires althea

... Angel has been facing financial difficulties, as it has had problems reaching a viable level of revenues. In its most recent financial statement (six months to September 2012), the company recorded a loss of £2.9 million ($4.3 million) on revenues of only £1 million ($1.5 million). For the financial ...
NEWER COMBINATION OF ACETYL SALICYLIC ACID AND NICOTINIC ACID IN BILAYER  MATRIX TABLETS FOR DYSLIPIDEMIA: DESIGN AND EVALUATION THEREOFF 
NEWER COMBINATION OF ACETYL SALICYLIC ACID AND NICOTINIC ACID IN BILAYER  MATRIX TABLETS FOR DYSLIPIDEMIA: DESIGN AND EVALUATION THEREOFF 

... “People  with  heart  disease  should  be  on  ASA  anyway.”The  usual  prescription  for  NA  is always  accompanied with  ASA in variably  so  as  to  be  taken  half  an  hour  before  the  administration  of  NA.  This  means  there  is  a  duplication  of  efforts  of  taking  two  concomitant  ...
Sound-Alike/Look-Alike Drugs for Hospital
Sound-Alike/Look-Alike Drugs for Hospital

Interactions of herbs and food products with drugs
Interactions of herbs and food products with drugs

... interactions are enlisted in the Table 1 to 4. Enhancement of drug effect — interactions highlight the risks associated with Foods are intended to be safe for The effects of drugs may be enhanced concurrent use of herbal remedies and by a mechanism dissimilar from that human consumption, but at the ...
pharmaceutical processing
pharmaceutical processing

... Phytonics process • A new solvent based on hydrofluorocarbon-134a and a new technology to optimize its remarkable properties in the extraction of plant materials offer significant environmental advantages and health and safety benefits over traditional process for the production of high quality na ...
Adverse Drug Reaction Reports - Texas Department of State Health
Adverse Drug Reaction Reports - Texas Department of State Health

... process. His concern is the influence of withdrawing from these substances on violence. As a result of this concern, Dr. Baker is asking each facility to review these factors. The other area Dr. Baker expressed concern was the multiple drug formularies that our patients have to use as they move bet ...
Definitions and Concepts
Definitions and Concepts

... administration, e.g. an aqueous solution of a given drug administered by the oral and intramuscular routes. • By the same routes of administration but different types of dosage form, e.g. a tablet, a hard gelatin capsule and an aqueous suspension administered by the peroral route. • In the same type ...
controlled drugs
controlled drugs

IND, NDA, ANDA, CONCEPT OF PARA I TO IV,
IND, NDA, ANDA, CONCEPT OF PARA I TO IV,

... A critical part of the NDA is the proposed labeling, which includes container labels, package insert, and any patient information leaflet. Actually, technical sections c, d, e, and f (above) are evaluated by the FDA to see if they support the indications and directions for use spelled out in the pac ...
KINETIC STUDY OF THE IN VITRO RELEASE AND STABILITY OF... FLOATING BEADS Research Article
KINETIC STUDY OF THE IN VITRO RELEASE AND STABILITY OF... FLOATING BEADS Research Article

... systems [3] are among the mechanisms available for controlling the gastric retention of solid dosage forms. Floating drug delivery systems are classified depending on the use of 2 formulation variables: effervescent and noneffervescent systems. Effervescent floating dosage forms are matrix types of ...
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Compounding

Pharmaceutical compounding (done in compounding pharmacies) is the creation of a particular pharmaceutical product to fit the unique need of a patient. To do this, compounding pharmacists combine or process appropriate ingredients using various tools. This may be done for medically necessary reasons, such as to change the form of the medication from a solid pill to a liquid, to avoid a non-essential ingredient that the patient is allergic to, or to obtain the exact dose(s) needed or deemed best of particular active pharmaceutical ingredient(s). It may also be done for more optional reasons, such as adding flavors to a medication or otherwise altering taste or texture. Compounding is most routine in the case of intravenous/parenteral medication, typically by hospital pharmacists, but is also offered by privately owned compounding pharmacies and certain retail pharmacies for various forms of medication. Whether routine or rare, intravenous or oral, etc., when a given drug product is made or modified to have characteristics that are specifically prescribed for an individual patient, it is known as ""traditional"" compounding.Due to the rising cost of compounding and the shortage of drugs, many hospitals have shown a tendency to rely more upon large-scale compounding pharmacies to meet their regular requirement, particularly of sterile-injectable medications. When compounding is done on bulk production of a given formulation rather than patient-specific production, it is known as ""non-traditional"" compounding (which, as discussed below, is arguably not ""compounding"" but rather ""manufacturing""). This development raises concerns about patient safety and makes a case for proper regulatory control and monitoring.
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