• Study Resource
  • Explore Categories
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Toxicological Findings in Cases of Alleged Drug
Toxicological Findings in Cases of Alleged Drug

... to cause anterograde amnesia so that the victim has no recollection of events6,8,13. These effects can all increase the victim’s susceptibility to sexual assault. A typical scenario involves the victim having ingested a drink (often bought by an unknown individual) after which they had little, parti ...
Cholinoceptor blocking drugs
Cholinoceptor blocking drugs

... • Used for the treatment of organophosphorus poisoning. • They are known as oxime agents and include Pralidoxime (PAM) & diacetylmonoxime • The oxime group has a high affinity for binding with Phosphorus atom and hydrolyze the phosphorylated enzyme. pralidoxime i.v.1-2 g for over 15-30 min. and for ...
Chemical Contamination - Risk Prevention in Infusion Therapy
Chemical Contamination - Risk Prevention in Infusion Therapy

... Sarto et al. 1990]. Since chromosomal mutagenicity following exposure is stochastic in nature [Health Counsel 1994], as little as one molecule could cause a mutation. For this reason, regulatory bodies do not quote threshold levels under which exposure is acceptable. ...
Chapter 19 Drugs: Chemical Cures, Comforts, and Cautions
Chapter 19 Drugs: Chemical Cures, Comforts, and Cautions

... New Uses for Old Drugs • Cost of developing a drug ~$800 million • Cheaper to use existing drug • Aspirin: original developed as painkiller – Prevents strokes and heart attacks – May show promise in fighting cancer and in delaying onset of Alzheimer’s disease ...
Chapter 19 Drugs: Chemical Cures, Comforts, and Cautions
Chapter 19 Drugs: Chemical Cures, Comforts, and Cautions

... • Activates brain’s reward system • Causes euphoric feeling by releasing dopamine • Legitimate medical uses – Treat glaucoma – Relieves nausea of cancer patients ...
THE KOREAN HERBAL PHARMACOPOEIA
THE KOREAN HERBAL PHARMACOPOEIA

... 7. In stating the amount of content in pharmaceutical preparations, the use of an expression “not less than 95.0% and not more than 105.0%” or “not less than 95.0% and not more than 110.0%”, for example, indicates that it is usually prepared so as to contain the labeled amount of the chemically pure ...
Marketed Unapproved Drugs
Marketed Unapproved Drugs

... the health care community are provided with established and emerging drug safety information so that they can make the best possible medical decisions about the safe and effective use of drugs.”38 However, aside from this broad drug safety initiative, there are other factors catalyzing FDA enforceme ...
1 Top Pediatric Medications Common Pediatric Conditions
1 Top Pediatric Medications Common Pediatric Conditions

... Children one to 12 years of age. Metabolism: ◦ Is generally faster than normal adult levels until age 2, then slowly declines until puberty, and finally drops to normal adult levels. ◦ This may mean increased dosage or dosing frequency for drugs eliminated by hepatic metabolism. ...
Power Point - New Mexico Pharmacists Association
Power Point - New Mexico Pharmacists Association

... • List 3 physiologic changes in older adults that increase the risk of drug side effects. • List 3 basic principles of prescribing medications for older ...
Simon Zheng - A Critical Review of Natural Language Processing Approaches to Discovering Drug-Drug Interactions from Medical Literatur
Simon Zheng - A Critical Review of Natural Language Processing Approaches to Discovering Drug-Drug Interactions from Medical Literatur

... However, with the steadily increasing number of drugs on the market and an aging population with growing medical needs, the study of drug-drug interactions has become more important in increasing longevity and quality of life. According to the National Health and Nutrition Examination Survey, over 7 ...
Drug use in renal and hepatic disorders.
Drug use in renal and hepatic disorders.

... ECF ( ascites, edema) & ↓↓ muscle mass. •↓↓ plasma protein binding due to impaired albumin production or drug displacement from accumulated substance normally cleared by the liver •↑ Bio avail through ↓↓ first pass metabolism •↓↓ Bioavailability due to malabsorption of fats in cholestatic liver dise ...
Impact of drug importation on community pharmacy and patient care
Impact of drug importation on community pharmacy and patient care

... between the United States and other countries. Some attention has been given to the impact of drug importation on the pharmaceutical research industry, its ...
Chapter 5 Drug Toxicity
Chapter 5 Drug Toxicity

... effects can range in severity from nuisance to life threatening. These effects make many patients unwilling to take drugs on a regular basis, and this lack of compliance represents a major practical limitation of pharmacotherapy. Drug toxicology focuses on the harmful effects of drugs in the animal ...
Drug Elimination
Drug Elimination

... ECF ( ascites, edema) &  muscle mass. • plasma protein binding due to impaired albumin production or drug displacement from accumulated substance normally cleared by the liver • Bio avail through  first pass metabolism • Bioavailability due to malabsorption of fats in cholestatic liver dise ...
Ch3 Pharmacokinetics pharmacodynamics- student pt 1
Ch3 Pharmacokinetics pharmacodynamics- student pt 1

... • ___________________: drug is injected directly into a vein. It is carried toward the heart where it is diluted before being distributed throughout the body. • IV ___________- single, large volume injected at once • IV _______________- drug is slowly injected (dripped) into a vein over time. Resul ...
Health Policy Center Publication
Health Policy Center Publication

... strength, quality, or purity of the drugs was compromised as a result of their sale, storage, handling, return, and resale. There is a legitimate risk to patient health that could result if the quality of returned goods was compromised after initial dispensing by the pharmacists. Our modifications t ...
1 DRUGS IN ADVANCED CARDIAC LIFE SUPPORT
1 DRUGS IN ADVANCED CARDIAC LIFE SUPPORT

... • Haemodynamically stable VT (Class IIb) • Refractory VF / pulseless VT (Class indeterminate) • Control of haemodynamically compromising PVCs (Class indeterminate) Note : Lignocaine is now a second choice behind other alternative agents in many of these ...
Traditional medicine-inspired approaches to drug discovery: can
Traditional medicine-inspired approaches to drug discovery: can

... The FDA and a few other agencies have come up with practical guidelines for botanical ‘drug’ development [42]. A botanical drug product often has unique features and may include complex mixtures with as yet unknown active ingredients Some botanical drugs, including cascara, psyllium and senna, are i ...
Introduction CPX-351 Dramatically Increases Plasma Cyt and Daun
Introduction CPX-351 Dramatically Increases Plasma Cyt and Daun

... outcomes, where statistically significant increases in overall survival were observed in unfavorable/poor risk AML patient populations in two randomized Phase 2 studies. While prolonged exposure to very high drug concentrations in plasma and systemic maintenance of the 5:1 molar Cyt:Daun ratio provi ...
assembly committee on public safety
assembly committee on public safety

... effects of alcohol. Certain generalizations can be made: high doses generally have a larger effect than small doses; well-learned tasks are less affected than novel tasks; and certain variables, such as prior exposure to a drug, can either reduce or accentuate expected effects, depending on circumst ...
Acid-Base Properties of Drugs - NSU College of Pharmacy
Acid-Base Properties of Drugs - NSU College of Pharmacy

... Fig.2.10. shows a hypothetical equilibration of pyrimethamine across the renal tubule (nephron), with a concentration of 1 µM. The acid -base equilibrium for this drug (Fig.2.9.; Eq.2.28. see the Answer to previous Activity) will be established on both sides of the membrane. A weak base like pyrimet ...
2014 Report on prescription drug costs
2014 Report on prescription drug costs

... than traditional drug utilization. Hemophilia drugs saw the most intense increase in use. While this drove a higher drug trend for hemophilia drugs, the small user population size meant the effect on overall drug costs was ...
kutki churna - International Journal of Research in Ayurveda and
kutki churna - International Journal of Research in Ayurveda and

... stability. Some Physico-Chemical tests were also performed to assess the stability of the concerned drug formulation. Churna (powder) preparations are widely and largely used in pharmacy as well as by practitioners of Ayurveda for According to Ayurvedic different ailments. pharmaceutical science, ch ...
Chain of Survival and EMSC
Chain of Survival and EMSC

... Medications given by the person preparing them Medications are not to be left at the bedside Narcotics and controlled substances kept under lock and key Orders must be checked before drugs are given Distractions must be avoided when medications ...
C h a p t e r 1 8 Chirally Pure Drugs in Hypertension
C h a p t e r 1 8 Chirally Pure Drugs in Hypertension

... the highest therapeutic activity. Thus separation of chirally pure drugs becomes very important. ASOMEX (S-Amlodipine), which is the chirally pure form of amlodipine, has a proven clinical efficacy in the treatment of hypertension. It has been extensively studied in the clinical set-up. A trial in 1 ...
< 1 ... 54 55 56 57 58 59 60 61 62 ... 161 >

Orphan drug

An orphan drug is a pharmaceutical agent that has been developed specifically to treat a rare medical condition, the condition itself being referred to as an orphan disease.In the US and EU it is easier to gain marketing approval for an orphan drug, and there may be other financial incentives, such as extended exclusivity periods, all intended to encourage the development of drugs which might otherwise lack a sufficient profit motive. The assignment of orphan status to a disease and to any drugs developed to treat it is a matter of public policy in many countries, and has resulted in medical breakthroughs that may not have otherwise been achieved due to the economics of drug research and development.According to Thomson Reuters in their 2012 publication ""The Economic Power of Orphan Drugs"", there has been increased investing in orphan drug Research and Development partly due to the U. S. Orphan Drug Act (ODA) 1983 and similar Acts in other regions of the world and also driven by ""high-profile philanthropic funding."" The period between 2001 to 2011 was the ""most productive period in the history of orphan drug development, in terms of average annual orphan drug designations and orphan drug approvals."" For the same decade the compound annual growth rate (CAGR) of the orphan drugs was an ""impressive 25.8 percent, compared to only 20.1 percent for a matched control group of non-orphan drugs."" By 2012 the market for orphan drugs was worth USD$637 million compared to the USD$638 million matched control group of non-orphan drugs, Thomson Reuters.By 2012, ""the revenue-generating potential of orphan drugs [was] as great as for non-orphan drugs, even though patient populations for rare diseases are significantly smaller. Moreover, we suggest that orphan drugs have greater profitability when considered in the full context of developmental drivers including government financial incentives, smaller clinical trial sizes, shorter clinical trial times and higher rates of regulatory success.""
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report