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2011 GEM Drugs Elderly
2011 GEM Drugs Elderly

... Unnecessary drug therapy (not indicated) Need for additional drug therapy Ineffective drug (needs an alternative) Dose too low Dose too high Adverse Drug Reaction (ADR) Noncompliance/Nonadherence ...
Week 2: (2/4) The Medical Technology Economy
Week 2: (2/4) The Medical Technology Economy

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Lecture 1
Lecture 1

... The remedy is mainly extracted from the plants, animals and minerals. The medicinal extract is diluted and potentiated to such an extent that not even an atom of the mother material can be detected in the remedy by the time it reaches the 12th potency. Dilutions are done in steps. For example: In th ...
Slide 1
Slide 1

... Prescribing for patients with liver disease: • if possible, use drugs that are eliminated by routes other than the liver • response and untoward effects should be monitored (and therapy adjusted accordingly) • predictable hepatotoxins (cytostatic drugs) should only be used for the strongest of indi ...
Psychoactive drugs - Stamford High School
Psychoactive drugs - Stamford High School

... the brain seconds after being smoked or injected. Once in the blood, crack causes the heart rate and blood pressure to soar to dangerous levels. ...
WORKING WITH PHARMA SPONSORS IN RESEARCH
WORKING WITH PHARMA SPONSORS IN RESEARCH

... Pharmaceutical Industry: Drug Development • 1999: 1,800 compounds in development • 2009: 2,900 medicines in development • 2008: Food and Drug Administration approved 31 drugs and biologics • 2006: cost to develop a drug $1.3 billion dollars and takes between 10 and 15 years ...
CLINICAL PHARMACOLOGY OF DRUGS AFFECTING THE
CLINICAL PHARMACOLOGY OF DRUGS AFFECTING THE

... Acute treatment • The doses of these drugs are lower when they are given by intramuscular injection than by mouth. This is particularly true if patients are very physically active (agitated), as this will increase the speed of absorption from the muscle. • Review the dose daily to avoid over-sedatio ...
Advisory Committee Mtgs. Sample PPT
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Absorption, distribution, metabolism and excretion
Absorption, distribution, metabolism and excretion

...  Some capsules and tablets contain sustaine-drelease drugs, which dissolve over an extended period of time.  Administration of oral drugs is relatively easy for patients who are alert and can swallow (can not be used in unconscious patients).  Certain drugs are given by the sublingual (placed und ...
Common Side Effects of Drug - WCCS E
Common Side Effects of Drug - WCCS E

... • The use of the term addiction is sometimes confusing. It is often used interchangeably with dependence, either physiological or psychological in nature; other times, it is used synonymously with the term drug abuse. A more accurate definition is the compulsive drug use despite negative ...
B.C. PharmaCare Drug Information Sheet for drug generic name
B.C. PharmaCare Drug Information Sheet for drug generic name

... • input from physicians, patients, caregivers, patient groups and drug submission sponsors The Ministry makes PharmaCare coverage decisions by taking into account: • the existing PharmaCare policies, programs and resources • the evidence-informed advice of the DBC • the drugs already covered by Phar ...
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dermatology - Bradford VTS

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Potentially inappropriate drug use and hip

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Drugs Hanson 15

... differently by the public since the classifications were established by the Durham-Humphrey Amendment of 1951. • In general, the public views OTC drugs as less effective, safe, and rarely abused and prescription drugs as more potent and potentially dangerous. However, these distinctions are not alwa ...
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... and lorazepam) 100,784 drug abuse cases in 2002 opioid pain relievers (e.g., oxycodone, hydrocodone, morphine, methadone, and combinations that include these drugs). 119,000 Taken due to Drug addiction and desired psychoactive effects ...
HIV Negative
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... analogues provide another 470 million pounds (750 million dollars) in sales. We know that something doesn’t have to be good for you to be profitable. Think of cigarettes or alcohol or fast-food. But it’s medication we’re talking about, not French fries. You’d think that a ...
History
History

... Replaces the Pure Food and Drug Act of 1906. Establishes requirements for identity, quality, and strength of drugs. Extends coverage to include cosmetics and medical devices. Requires manufacturers to prove safety of new drugs. Mandates FDA review and approval of new drugs. Controls the packaging an ...
Integrating drug concentrations and minimum inhibitory concentrations with Bayesian-dose optimisation for multidrug-
Integrating drug concentrations and minimum inhibitory concentrations with Bayesian-dose optimisation for multidrug-

... minimum inhibitory concentrations with Bayesian-dose optimisation for multidrugresistant tuberculosis To the Editor: The problems of multidrug-resistant (MDR) tuberculosis (TB), extensively drug-resistant (XDR) TB, and even ‘‘totally drug-resistant’’ TB (a term that is still debated), have exposed t ...
Drugs Affecting the Gastrointestinal System and Nutrition
Drugs Affecting the Gastrointestinal System and Nutrition

... magnesium or MOM can cause diarrhea. Calcium products can cause kidney stones. Sodium bicarbonate products can cause ...
Chapter 16 Cholinesterase Inhibitors
Chapter 16 Cholinesterase Inhibitors

... structural or chemical abnormalities May occur with diarrhea, constipation, or both Considered IBS when symptoms have been present for 12 weeks over the past year ...
T 1/2
T 1/2

... Inhibition of drug biotransformation enzymes results in elevated levels of the parent drug, prolonged pharmacological effects, and an increased incidence of drug-induced toxicity. ...
ABSORPTION OF DRUGS
ABSORPTION OF DRUGS

... are more rapidly soluble than when given in oily solution, suspension or solid form.  3- Dosage form: Tablets and capsules, rate of disintegration and dissolution is limiting factor in their absorption. After dissolution, smaller the particle size, ...
Drug - Weld RE-4 School District
Drug - Weld RE-4 School District

... Using a drug without following the instructions on the label Using a drug not prescribed for you Allowing someone else to use a drug prescribed for you Taking more of the drug than the doctor prescribed Using the drug longer than advised by the doctor ...
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Orphan drug

An orphan drug is a pharmaceutical agent that has been developed specifically to treat a rare medical condition, the condition itself being referred to as an orphan disease.In the US and EU it is easier to gain marketing approval for an orphan drug, and there may be other financial incentives, such as extended exclusivity periods, all intended to encourage the development of drugs which might otherwise lack a sufficient profit motive. The assignment of orphan status to a disease and to any drugs developed to treat it is a matter of public policy in many countries, and has resulted in medical breakthroughs that may not have otherwise been achieved due to the economics of drug research and development.According to Thomson Reuters in their 2012 publication ""The Economic Power of Orphan Drugs"", there has been increased investing in orphan drug Research and Development partly due to the U. S. Orphan Drug Act (ODA) 1983 and similar Acts in other regions of the world and also driven by ""high-profile philanthropic funding."" The period between 2001 to 2011 was the ""most productive period in the history of orphan drug development, in terms of average annual orphan drug designations and orphan drug approvals."" For the same decade the compound annual growth rate (CAGR) of the orphan drugs was an ""impressive 25.8 percent, compared to only 20.1 percent for a matched control group of non-orphan drugs."" By 2012 the market for orphan drugs was worth USD$637 million compared to the USD$638 million matched control group of non-orphan drugs, Thomson Reuters.By 2012, ""the revenue-generating potential of orphan drugs [was] as great as for non-orphan drugs, even though patient populations for rare diseases are significantly smaller. Moreover, we suggest that orphan drugs have greater profitability when considered in the full context of developmental drivers including government financial incentives, smaller clinical trial sizes, shorter clinical trial times and higher rates of regulatory success.""
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