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... - uninducible: mutant that cannot be expressed at all. - constitutive gene expression: the continued expression of a gene that does not respond to regulation The operator was originally identified by constitutive mutations, denoted OC. The mutation changes the operator so that the repressor no lon ...
... - uninducible: mutant that cannot be expressed at all. - constitutive gene expression: the continued expression of a gene that does not respond to regulation The operator was originally identified by constitutive mutations, denoted OC. The mutation changes the operator so that the repressor no lon ...
20.15 Enhancers contain the same elements that are
... An authentic GAL4 protein can activate a target gene only if it has a UAS. The LexA repressor by itself of course lacks the ability to activate either sort of target. The LexA-GAL4 hybrid can no longer activate a gene with a UAS, but it can now activate a gene that has a LexA operator! This result f ...
... An authentic GAL4 protein can activate a target gene only if it has a UAS. The LexA repressor by itself of course lacks the ability to activate either sort of target. The LexA-GAL4 hybrid can no longer activate a gene with a UAS, but it can now activate a gene that has a LexA operator! This result f ...
How Optimized Is the Translational Machinery in
... i.e., the increase in Y, is outstanding (Figure 1). Y will be the same as that in the baseline condition when Q j exactly matches p j , e.g., when Q 1 5 p 1 in Figure 1. The baseline condition therefore seems to guarantee a relatively small Y value over a wide fluctuation of Q j values. Y will be sm ...
... i.e., the increase in Y, is outstanding (Figure 1). Y will be the same as that in the baseline condition when Q j exactly matches p j , e.g., when Q 1 5 p 1 in Figure 1. The baseline condition therefore seems to guarantee a relatively small Y value over a wide fluctuation of Q j values. Y will be sm ...
CHaPter 2 Nucleic acids and proteins: a review
... the bands down the column corresponds to the gene sequence. New techniques of sequencing are described in the box below. Are gene sequencers used only for human genes? No! The genetic material of all organisms is DNA and the structure of that DNA is identical, regardless of whether it comes from whe ...
... the bands down the column corresponds to the gene sequence. New techniques of sequencing are described in the box below. Are gene sequencers used only for human genes? No! The genetic material of all organisms is DNA and the structure of that DNA is identical, regardless of whether it comes from whe ...
Molecular basis for the recently described hereditary
... in every cell of nearly all organisms. It is a multimer shell composed of 24 heavy (H, Mr 21,000) and light (L, Mr 19,000) subunits, surrounding a cavity that can accommodateup to 4,500 iron atoms in a readily available but nontoxic form.’ The human genes for the H and L femtin subunits have been as ...
... in every cell of nearly all organisms. It is a multimer shell composed of 24 heavy (H, Mr 21,000) and light (L, Mr 19,000) subunits, surrounding a cavity that can accommodateup to 4,500 iron atoms in a readily available but nontoxic form.’ The human genes for the H and L femtin subunits have been as ...
PlantRNA, a database for tRNAs of photosynthetic eukaryotes
... (19,20). The number and identity of mitochondriaimported tRNAs greatly vary between species and this is especially true in the plant kingdom. Here, based on experimental evidence or on the insufficient number of mitochondrial tRNA genes, the PlantRNA database provides information on tRNA mitochondria ...
... (19,20). The number and identity of mitochondriaimported tRNAs greatly vary between species and this is especially true in the plant kingdom. Here, based on experimental evidence or on the insufficient number of mitochondrial tRNA genes, the PlantRNA database provides information on tRNA mitochondria ...
Molecular Basis for the Recently Described Hereditary
... in every cell of nearly all organisms. It is a multimer shell composed of 24 heavy (H, Mr 21,000) and light (L, Mr 19,000) subunits, surrounding a cavity that can accommodateup to 4,500 iron atoms in a readily available but nontoxic form.’ The human genes for the H and L femtin subunits have been as ...
... in every cell of nearly all organisms. It is a multimer shell composed of 24 heavy (H, Mr 21,000) and light (L, Mr 19,000) subunits, surrounding a cavity that can accommodateup to 4,500 iron atoms in a readily available but nontoxic form.’ The human genes for the H and L femtin subunits have been as ...
Classification of Medically Important Viruses
... *These are enveloped viruses with an icosahedral capsid. *Two identical strands (said to be "diploid") of singlestranded, linear, positive-polarity RNA. * The term "retro" pertains to the reverse transcription of the RNA genome into DNA. * There are two medically important groups: (1) the oncovirus ...
... *These are enveloped viruses with an icosahedral capsid. *Two identical strands (said to be "diploid") of singlestranded, linear, positive-polarity RNA. * The term "retro" pertains to the reverse transcription of the RNA genome into DNA. * There are two medically important groups: (1) the oncovirus ...
RNA Processing
... (a) Cell cycle–stimulating pathway. This pathway is triggered by 1 a growth factor that binds to 2 its receptor in the plasma membrane. The signal is relayed to 3 a G protein called Ras. Like all G proteins, Ras is active when GTP is bound to it. Ras passes the signal to 4 a series of protein kinase ...
... (a) Cell cycle–stimulating pathway. This pathway is triggered by 1 a growth factor that binds to 2 its receptor in the plasma membrane. The signal is relayed to 3 a G protein called Ras. Like all G proteins, Ras is active when GTP is bound to it. Ras passes the signal to 4 a series of protein kinase ...
Coevolution of an aminoacyl-tRNA synthetase with its tRNA substrates
... (from E. coli to D. radiodurans and Corynebacterium) of the genes encoding these precisely truncated GluRS fragments suggests that these proteins may have a yet unknown function. Nonetheless, GluX was not analyzed further. Class I lysyl-tRNA synthetase (LysRS) is structurally very related (27) and d ...
... (from E. coli to D. radiodurans and Corynebacterium) of the genes encoding these precisely truncated GluRS fragments suggests that these proteins may have a yet unknown function. Nonetheless, GluX was not analyzed further. Class I lysyl-tRNA synthetase (LysRS) is structurally very related (27) and d ...
Lecture 21: Structure of Prokaryotic Cells
... the inner most of mitochondria and it contains ribosome, DNA, RNA, enzymes to run kreb cycle and other proteins. Mitochondrial DNA is circular and it has full machinery to synthesize its own RNA (mRNA, rRNA and t-RNA) and proteins. A number of difference exist between mitochondrial DNA and DNA prese ...
... the inner most of mitochondria and it contains ribosome, DNA, RNA, enzymes to run kreb cycle and other proteins. Mitochondrial DNA is circular and it has full machinery to synthesize its own RNA (mRNA, rRNA and t-RNA) and proteins. A number of difference exist between mitochondrial DNA and DNA prese ...
The transformation suppressor protein Pdcd4 shuttles
... eucaryotic translation initiation factors (eIFs) eIF4A and eIF4G (Göke et al., 2002; Kang et al., 2002; Yang et al., 2003), suggesting that it might be involved in regulating protein translation. In support of this idea, Yang et al. (2003) have localized the protein to the cytoplasm and have demons ...
... eucaryotic translation initiation factors (eIFs) eIF4A and eIF4G (Göke et al., 2002; Kang et al., 2002; Yang et al., 2003), suggesting that it might be involved in regulating protein translation. In support of this idea, Yang et al. (2003) have localized the protein to the cytoplasm and have demons ...
Complete Thyroxine-Binding Globulin (TBG) Deficiency Produced
... To evaluate the effect of this mutation on the splicing pattern, it was necessary to determine the sequence of TBG mRNA. TBG mRNA is transcribed in liver and therefore is not readily accessible for sampling. We attempted illegitimate amplification of TBG mRNA from peripheral blood leukocytes, as pre ...
... To evaluate the effect of this mutation on the splicing pattern, it was necessary to determine the sequence of TBG mRNA. TBG mRNA is transcribed in liver and therefore is not readily accessible for sampling. We attempted illegitimate amplification of TBG mRNA from peripheral blood leukocytes, as pre ...
Identification and expression of the first nonmammalian amyloid‐β
... members contain conserved zinc-binding [13,14], heparinbinding [14] and collagen-binding domains [15]. Furthermore, a GTP-binding protein (G0) binding site [16] and the NPXY-sequence responsible for clathrin-coated vesicle targeting [17] are present within the cytoplasmic tail of all family members. ...
... members contain conserved zinc-binding [13,14], heparinbinding [14] and collagen-binding domains [15]. Furthermore, a GTP-binding protein (G0) binding site [16] and the NPXY-sequence responsible for clathrin-coated vesicle targeting [17] are present within the cytoplasmic tail of all family members. ...
Plant Physiology
... Analysis of RNA expression in northern blots was carried out essentially as described in Pawlowski et al. (1994). Dg93 cDNA was excised from the Bluescript phagemid vector and radiolabeled by incorporation of [␣-32P]dCTP (Amersham, Arlington Heights, IL) using the Multiprime DNA Labeling System (Ame ...
... Analysis of RNA expression in northern blots was carried out essentially as described in Pawlowski et al. (1994). Dg93 cDNA was excised from the Bluescript phagemid vector and radiolabeled by incorporation of [␣-32P]dCTP (Amersham, Arlington Heights, IL) using the Multiprime DNA Labeling System (Ame ...
Relative expression of wild-type and activated Ki
... species of transcript is a direct linear function of the ratio of their amplified, reverse-transcribed cDNAs. We attribute the simplicity of this relationship to the fact that no correction is required to match the efficiencies of synthesis of the mutant and wild-type products: during both reverse t ...
... species of transcript is a direct linear function of the ratio of their amplified, reverse-transcribed cDNAs. We attribute the simplicity of this relationship to the fact that no correction is required to match the efficiencies of synthesis of the mutant and wild-type products: during both reverse t ...
Bacterial Gene Regulation
... • Constitutive transcription – continuous expression usually for genes that perform routine tasks necessary for life • Regulated transcription – expression at particular times for genes that are differentially required under varied conditions • Regulated transcription includes control of both in ...
... • Constitutive transcription – continuous expression usually for genes that perform routine tasks necessary for life • Regulated transcription – expression at particular times for genes that are differentially required under varied conditions • Regulated transcription includes control of both in ...
- SciTech Connect
... the RNA-inducing silencing complex (RISC). Using the siRNA as a guide, RISC targets homologous mRNAs for cleavage and degradation, resulting in post-transcriptional gene silencing. The miRNA pathway processes RNAs that form hairpin structures, which are expressed from miRNA loci within the genome (F ...
... the RNA-inducing silencing complex (RISC). Using the siRNA as a guide, RISC targets homologous mRNAs for cleavage and degradation, resulting in post-transcriptional gene silencing. The miRNA pathway processes RNAs that form hairpin structures, which are expressed from miRNA loci within the genome (F ...
Histones - scientia.global
... coordinated fashion to bind DNA to form chromatin. The genes H2A, H2B, H3 and H4 encode histone proteins that make up the nucleosome, while the H1 histones are bound to the linker DNA, found between the nucleosomes. Interestingly, the mRNAs of the canonical histone proteins do not have poly(A) tails ...
... coordinated fashion to bind DNA to form chromatin. The genes H2A, H2B, H3 and H4 encode histone proteins that make up the nucleosome, while the H1 histones are bound to the linker DNA, found between the nucleosomes. Interestingly, the mRNAs of the canonical histone proteins do not have poly(A) tails ...
Slide 1
... Proteins can carry intrinsically disordered regions These regions can be predicted from sequence Eukaryotic proteins are more disordered ...
... Proteins can carry intrinsically disordered regions These regions can be predicted from sequence Eukaryotic proteins are more disordered ...
Opportunities in Bioinformatics for Computer - People
... • Long molecules of DNA: 10^4 to 10^8 base pairs • 26 matched pairs in humans • A gene is a subsequence of a chromosome that encodes a protein. • Proteins associated with cell function, structure, and regulation. • Only a fraction of the genes are in use at any time. • Every gene is present in every ...
... • Long molecules of DNA: 10^4 to 10^8 base pairs • 26 matched pairs in humans • A gene is a subsequence of a chromosome that encodes a protein. • Proteins associated with cell function, structure, and regulation. • Only a fraction of the genes are in use at any time. • Every gene is present in every ...