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N o v e l s ite s  o...  Johan Ohlson
N o v e l s ite s o... Johan Ohlson

... The number of protein-coding genes are likely not sufficient to account for the complexity of higher organisms. It is plausible that the proteome is responsible for the complexity of an organism. An important mechanism that increases the protein variability is posttranscriptional modifications that ...
Aptamers as Drugs. PDF
Aptamers as Drugs. PDF

... oligonucleotides have been shown to contain oligonucleotide ligands that bind tightly to various target compounds other than nucleic acid molecules having complementary sequences, revealing that oligonucleotides can have binding activities beyond those specified by Watson-Crick base-pairing6-9. RNA ...
Molecular Evolution of Functional Nucleic Acids
Molecular Evolution of Functional Nucleic Acids

... enzyme, while the catalytic domain of the former was 12 bases, which is smaller than that of the latter. These results indicate that the zinc ion, with which imidazoyl group is coordinated, could effectively work as catalyst. Perrin et al. obtained a modified DNA enzyme from a library of doubly modi ...
Isolation and characterization of an RNA that binds with high affinity
Isolation and characterization of an RNA that binds with high affinity

RNA-based regulation of genes of tryptophan synthesis
RNA-based regulation of genes of tryptophan synthesis

... processes influence trp mRNA synthesis and survival, trp coding region translation, trp enzyme function and turnover, and trp enzyme activity (Landick and Yanofsky 1987; Yanofsky and Crawford 1987). For example, and most importantly, the activity of the first enzyme of the tryptophan biosynthetic pa ...
Chapter 1
Chapter 1

... primary transcript that are not protein coding • Bacterial chromosomes are continuous – all DNA sequence from the chromosome is found in the mRNA • Eukaryotic chromosomes are discontinuous – There are extra DNA sequences within the genes that do not encode any amino acid sequence called introns or i ...
A-level Biology Mark scheme Unit 05
A-level Biology Mark scheme Unit 05

... relevant questions, by a panel of subject teachers. This mark scheme includes any amendments made at the standardisation events which all associates participate in and is the scheme which was used by them in this examination. The standardisation process ensures that the mark scheme covers the studen ...
The structure and function of proline
The structure and function of proline

Xenobiotic
Xenobiotic

... • monooxygenase = from O2 one atom O is inserted into substrate (between carbon and hydrogen atom) • the second O atom makes H2O, 2H come from NADPH+H+ • dioxygen is reduced to -OH group and water ...
Protein translation in Plasmodium parasites
Protein translation in Plasmodium parasites

... Peptide exit tunnel: the site, formed by proteins and rRNA, where the nascent polypeptide chain leaves the ribosome. P-granules: translationally silent storage particles containing high levels of non-translated mRNA. Related to P-bodies, but differ in their inability to degrade mRNA. Plastid: endosy ...
Carbohydrate and sugar structure
Carbohydrate and sugar structure

... Isozymes: Enzymes that catalyze the same reaction but are different in their kinetic behavior Tissue specific Glucokinase- Liver controls blood glucose levels. Hexokinase in muscle - allosteric inhibition by ATP Hexokinase in brain - NO allosteric inhibition by ATP ...
ppt
ppt

... When lactose is present, E. coli produce three enzymes involved in lactose metabolism. Lactose is broken into glucose and galactose, and galactose is modified into glucose, too. Glucose is then metabolized in aerobic respiration pathways to harvest energy (ATP). When lactose is absent, E. coli does ...
A nucleus-encoded chloroplast protein regulated by iron availability
A nucleus-encoded chloroplast protein regulated by iron availability

Control of Gene Expression
Control of Gene Expression

... Control of transcription is usually exerted at the step at which the process is initiated. In Chapter 7, we saw that the promoter region of a gene attracts the enzyme RNA polymerase and correctly orients the enzyme to begin its task of making an RNA copy of the gene. The promoters of both bacterial ...
Document
Document

... precursors into mature RNAs ready for translation. For example, the splicing process removes extended stretches of the nucleotide sequences called introns from an RNA precursor such that only the remaining RNA sequence codes for a protein. Besides these normal processing events, many novel phenomena ...
how cells read the genome: from dna to protein
how cells read the genome: from dna to protein

... have complete genome sequences for many organisms, including humans, and we therefore know the maximum amount of information that is required to produce a complex organism like ourselves. The limits on the hereditary information needed for life constrain the biochemical and structural features of ce ...
pdf
pdf

... have been obtained that either increase or decrease its efficiency of initiating transcription. Base substitutions that make the promoter sequence more similar to the consensus generate a stronger promoter (promoter "up" mutations) whereas those that make the promoter less similar to the consensus g ...
$doc.title

... b.     The  bacteria  can’t  ferment  sucrose  because  they  lack  an  enzyme  to  digest  it.   ...
Chapter 7
Chapter 7

... • Transcription alone does not account for gene expression • Regulatory mechanisms can operate at various stages after transcription • Such mechanisms allow a cell to fine-tune gene expression rapidly in response to environmental changes ...
4 Regulation Enzyme Activity GOB Structures
4 Regulation Enzyme Activity GOB Structures

... The rates of enzyme-catalyzed reactions are controlled by regulatory enzymes that • increase the reaction rate when more of a particular substance is needed. • decrease the reaction rate when that substance is not needed. Enzyme activity can be regulated by allosteric enzymes, feedback control, and ...
O - Portland State University
O - Portland State University

... Kelly Scientific Resources has an opening for an Extractions Technician at an environmental company in Tigard, OR.   This position has the potential to become a temp to hire opportunity.  The successful candidate will perform sample preparation duties including solvent extractions, solid phase extra ...
Infectious Pancreatic Necrosis Virus
Infectious Pancreatic Necrosis Virus

... found in farmed Salmonoid fish. The genome of this virus consists of two segments of double-stranded RNA packaged in a non-enveloped icosahedral capsid. The larger segment, A, is 3097 nucleotides long and encodes a 107kDa precursor protein made up of VP2, VP3 and VP4 from a single large open reading ...
Introduction
Introduction

... universal set of logic gates and a half-adder/half-subtractor system ...
Polyunsaturated fatty acids stimulate hepatic UCP
Polyunsaturated fatty acids stimulate hepatic UCP

... Also, most enzymes involved in lipogenesis, including fatty acid synthase, S14, and liver-type pyruvate kinase, are downregulated in the presence of fatty acids (1, 9, 20, 21). However, unlike the effect seen with the enzymes of ␤-oxidation, the inhibition of these genes appears to be mediated only ...
PDF
PDF

... None of these compounds caused any alterations of polarity. At non-toxic concentrations reconstitution was exclusively monopolar in form, even in isolated digestive zones. At lethal doses animals were axiate with easily recognizable polarity right up to, and during, disintegration; invariably the la ...
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