4._Bipolar_disorder_def
... Non-pharmacologic Approaches to the Treatment of Depression (e.g. psychotherapy, electroconvulsive therapy, repetitive trancranial magnetic stimulation, if disturbances in biorhythms – light, sleep deprivation, ...) ...
... Non-pharmacologic Approaches to the Treatment of Depression (e.g. psychotherapy, electroconvulsive therapy, repetitive trancranial magnetic stimulation, if disturbances in biorhythms – light, sleep deprivation, ...) ...
Possible Test Questions
... TCA’s and others. Common effects of H1 blockade include sedation and weight gain. - Alpha 1 Adrenergic Receptors – think catecholamines i.e. norepinephrine and epinephrine. Typically in psych drugs Alpha 1 receptors can be antagonized leading to the negative side effect of orthostatic hypotension. ...
... TCA’s and others. Common effects of H1 blockade include sedation and weight gain. - Alpha 1 Adrenergic Receptors – think catecholamines i.e. norepinephrine and epinephrine. Typically in psych drugs Alpha 1 receptors can be antagonized leading to the negative side effect of orthostatic hypotension. ...
File
... (Norepinephrine (NE) &/or Serotonin (5-HT)) in the CNS. Therefore, in the treatment we try to ↑ the level of ...
... (Norepinephrine (NE) &/or Serotonin (5-HT)) in the CNS. Therefore, in the treatment we try to ↑ the level of ...
Depression
... relief from anxiety and insomnia Significant CYP2D6 inhibition Sertraline: Increased number of GI adverse drug reactions ...
... relief from anxiety and insomnia Significant CYP2D6 inhibition Sertraline: Increased number of GI adverse drug reactions ...
Biological Therapies
... – Norepinephrine - ANS functions like bronchodilation and heart rate; CNS control of arousal and vigilance – Serotonin - CNS mechanisms of sleep and dreaming ...
... – Norepinephrine - ANS functions like bronchodilation and heart rate; CNS control of arousal and vigilance – Serotonin - CNS mechanisms of sleep and dreaming ...
Serotonin Syndrome - Utah Poison Control Center
... Serotonin is formed in biologic systems from the amino acid L-tryptophan. Once formed, it is stored or rapidly inactivated by monoamine oxidase. Serotonin is one of three monoamine neurotransmitters most often associated with depression. Although serotonin is generally associated with clinical depre ...
... Serotonin is formed in biologic systems from the amino acid L-tryptophan. Once formed, it is stored or rapidly inactivated by monoamine oxidase. Serotonin is one of three monoamine neurotransmitters most often associated with depression. Although serotonin is generally associated with clinical depre ...
cyclobenzaprine (sye-kloe-ben-za-preen) - DavisPlus
... Use Cautiously in: Cardiovascular disease; Geri: Appears on Beers list. Poorly tolerated due to anticholinergic effects; OB, Lactation, Pedi: Pregnancy, lactation, and children ⬍15 yr (safety not established). ⫽ Canadian drug name. ...
... Use Cautiously in: Cardiovascular disease; Geri: Appears on Beers list. Poorly tolerated due to anticholinergic effects; OB, Lactation, Pedi: Pregnancy, lactation, and children ⬍15 yr (safety not established). ⫽ Canadian drug name. ...
Roles of Different Neurotransmitters
... involved in memory seizures; this is why some people avoid MSG (monosodium glutamate) in food ...
... involved in memory seizures; this is why some people avoid MSG (monosodium glutamate) in food ...
Document
... May occur when SSRI taken with another medicine affecting the reuptake of serotonin E.g., MAOI, TCA, Lithium Serotonin accumulates in the body Mental status changes HTN Tremors, ataxia Hyperpyrexia, sweating ...
... May occur when SSRI taken with another medicine affecting the reuptake of serotonin E.g., MAOI, TCA, Lithium Serotonin accumulates in the body Mental status changes HTN Tremors, ataxia Hyperpyrexia, sweating ...
Click here for handout
... to the prevention of the serotonin syndrome. If multiple agents are required, however, computer-based ordering systems and the use of PDAs can detect drug interactions and decrease reliance on memory in drug ordering. Post-marketing surveillance linked to physician education has been proposed to imp ...
... to the prevention of the serotonin syndrome. If multiple agents are required, however, computer-based ordering systems and the use of PDAs can detect drug interactions and decrease reliance on memory in drug ordering. Post-marketing surveillance linked to physician education has been proposed to imp ...
Case: Young man, dance party, collapsed outside.
... Malignant hyperthermia Rare, familial myopathy Triggered by general anesthesia • Succinylcholine • Inhalational agents (eg, Halothane) ...
... Malignant hyperthermia Rare, familial myopathy Triggered by general anesthesia • Succinylcholine • Inhalational agents (eg, Halothane) ...
Psychopharmacology
... • Terotogenic: pulmonary HTN in newborn, heart defects, etc. • Bleeding risk: inhibits platelet coagulation • Serotonin Syndrome: caused by combining serotonin-acting medications ▫ Mild: restless, sweaty, tachy ▫ Moderate: HTN, hyperthermia, rigid, lethargic ▫ Severe: Seizures, shock and coma • Sero ...
... • Terotogenic: pulmonary HTN in newborn, heart defects, etc. • Bleeding risk: inhibits platelet coagulation • Serotonin Syndrome: caused by combining serotonin-acting medications ▫ Mild: restless, sweaty, tachy ▫ Moderate: HTN, hyperthermia, rigid, lethargic ▫ Severe: Seizures, shock and coma • Sero ...
Serotonin Syndrome - Clinician`s Brief
... coingestion of ≥2 drugs that alter serotonin metabolism via different mechanisms (eg, selective serotonin reuptake inhibitors [SSRIs], monoamine oxidase inhibitors [MAOIs]), although overdose of single agents has also been reported.1-3 ■ In veterinary medicine, most SS cases result from accidental i ...
... coingestion of ≥2 drugs that alter serotonin metabolism via different mechanisms (eg, selective serotonin reuptake inhibitors [SSRIs], monoamine oxidase inhibitors [MAOIs]), although overdose of single agents has also been reported.1-3 ■ In veterinary medicine, most SS cases result from accidental i ...
Neurotransmission in the CNS
... • ↓ of dopamine levels is a contributing factor in parkinson,s disease . Treatment by increasing dopamine content. ...
... • ↓ of dopamine levels is a contributing factor in parkinson,s disease . Treatment by increasing dopamine content. ...
Drug therapy - WordPress.com
... Research has been found to support the effect of drugs on treating symptoms of abnormality for the majority of cases. It is the most common treatment. Drugs to not work on all patients therefore suggesting there is more involved than biological abnormalities, causing a problem for the explanation an ...
... Research has been found to support the effect of drugs on treating symptoms of abnormality for the majority of cases. It is the most common treatment. Drugs to not work on all patients therefore suggesting there is more involved than biological abnormalities, causing a problem for the explanation an ...
投影片 1
... alpha2-adrenergic receptors. Blocking histamine (H1), 5-HT2 and 5-HT3 receptors. Causing less insomnia, sexual dysfunction, nausea/vomiting than SSRIs. Effective for pain, insomnia and anorexia/cachexia. Side effects: sedation, increased appetite, weight gain. ...
... alpha2-adrenergic receptors. Blocking histamine (H1), 5-HT2 and 5-HT3 receptors. Causing less insomnia, sexual dysfunction, nausea/vomiting than SSRIs. Effective for pain, insomnia and anorexia/cachexia. Side effects: sedation, increased appetite, weight gain. ...
NeuroCalm - Moss Nutrition
... to support calming brain activity and a reduction of stressrelated hypervigilance (an increased state of sensory sensitivity or watchfulness where a person is constantly tense or on guard). NeuroCalm™ promotes GABAnergic and seritonergic activity, to improve mood, reduce cravings and support greater ...
... to support calming brain activity and a reduction of stressrelated hypervigilance (an increased state of sensory sensitivity or watchfulness where a person is constantly tense or on guard). NeuroCalm™ promotes GABAnergic and seritonergic activity, to improve mood, reduce cravings and support greater ...
Vocabulary Terms [ 70 KB pdf ]
... Bias – inclination or prejudice for or against one person or group, especially in a way considered to be unfair. Blinding – a process where clinical trial researchers and/or participants are not told which treatment groups patients are assigned to. Cell Body - contains the neuron’s nucleus where man ...
... Bias – inclination or prejudice for or against one person or group, especially in a way considered to be unfair. Blinding – a process where clinical trial researchers and/or participants are not told which treatment groups patients are assigned to. Cell Body - contains the neuron’s nucleus where man ...
Antidepressants and Sedatives David G. Standaert, MD, Ph.D
... Non-selective, irreversible enzyme inhibitors - long duration of action Therapeutic effect is due to is enhancement of CNS amine levels Major adverse effects are due to excessive accumulation of amines in the circulation ...
... Non-selective, irreversible enzyme inhibitors - long duration of action Therapeutic effect is due to is enhancement of CNS amine levels Major adverse effects are due to excessive accumulation of amines in the circulation ...
A Dangerous Triad: Sertraline, Mirtazapine and Methadone
... syndrome fall into the three main areas of: Altered mental status, autonomic dysfunction and neuromuscular abnormalities [5]. The symptoms form part of the ‘Sternbach diagnostic criteria’ named after Dr. Harvey Sternbach who suggested that at least three of these features need to be seen before clas ...
... syndrome fall into the three main areas of: Altered mental status, autonomic dysfunction and neuromuscular abnormalities [5]. The symptoms form part of the ‘Sternbach diagnostic criteria’ named after Dr. Harvey Sternbach who suggested that at least three of these features need to be seen before clas ...
Antidepressants and Anxiolytics
... months – Newer: long term or lifelong therapy – Distinguish: situational/transient depression ...
... months – Newer: long term or lifelong therapy – Distinguish: situational/transient depression ...
Serotonin Syndrome - Available Courses
... ! Myoclonus, rigidity, incoordination, hyperreflxia, seizures (rare, usually tonic-clonic) C. Autonomic dysfunction ! Hyperthermia (reported in half of all cases), nausea, diarrhea, headache, mydriasis, nystagmus (rare), diaphoresis (reported in half of all cases), tachycardia, ventricular arrhythmi ...
... ! Myoclonus, rigidity, incoordination, hyperreflxia, seizures (rare, usually tonic-clonic) C. Autonomic dysfunction ! Hyperthermia (reported in half of all cases), nausea, diarrhea, headache, mydriasis, nystagmus (rare), diaphoresis (reported in half of all cases), tachycardia, ventricular arrhythmi ...
Document
... being mediated by a large and diverse range of 5-HT receptors. At least seven different receptor "families" are known to exist, each located in different parts of the body and triggering different responses. As with all neurotransmitters, the effects of 5-HT on the human mood and state of mind, and ...
... being mediated by a large and diverse range of 5-HT receptors. At least seven different receptor "families" are known to exist, each located in different parts of the body and triggering different responses. As with all neurotransmitters, the effects of 5-HT on the human mood and state of mind, and ...
Serotonin syndrome
Serotonin syndrome is a potential symptom of any number of life-threatening drug interactions which may follow therapeutic drug use, combination, overdose of particular drugs, or the recreational use of certain drugs. Serotonin syndrome is not an idiopathic drug reaction; it is a predictable consequence of excess serotonin on the CNS and/or peripheral nervous system. For this reason, some experts strongly prefer the terms serotonin toxicity or serotonin toxidrome which more accurately reflect that it is a form of poisoning. Other names include serotonin sickness, serotonin storm, serotonin poisoning, hyperserotonemia, or serotonergic syndrome.Excessive levels of serotonin produce a spectrum of specific symptoms including cognitive, autonomic, and somatic effects. Symptoms may range from barely perceptible to fatal. Numerous drugs and drug combinations have been reported to produce serotonin syndrome, though the exact mechanism is not well understood in many instances.Diagnosis includes observing symptoms and investigating patient history for causal factors (interacting drugs). The syndrome has a characteristic picture but can be mistaken for other illnesses in some people, particularly those with neuroleptic malignant syndrome. No laboratory tests can currently confirm the diagnosis. Hence it is diagnosed based on symptoms, disease course (that is, the progression of the disease) and the exclusion of other possible causes of the presenting symptoms.Treatment consists of discontinuing medications which may contribute and in moderate to severe cases administering a serotonin antagonist. An important adjunct treatment includes controlling agitation with benzodiazepine sedation. The high-profile case of Libby Zion, who is generally accepted to have died from serotonin syndrome, resulted in changes to graduate medical education in New York State.