投影片 1
... Indirectly increasing synaptic norepinephrine and serotonin through blockade of central presynaptic alpha2-adrenergic receptors. Blocking histamine (H1), 5-HT2 and 5-HT3 receptors. Causing less insomnia, sexual dysfunction, nausea/vomiting than SSRIs. Effective for pain, insomnia and anorexia/cachex ...
... Indirectly increasing synaptic norepinephrine and serotonin through blockade of central presynaptic alpha2-adrenergic receptors. Blocking histamine (H1), 5-HT2 and 5-HT3 receptors. Causing less insomnia, sexual dysfunction, nausea/vomiting than SSRIs. Effective for pain, insomnia and anorexia/cachex ...
depression
... Beneficial effects may not be seen in some patients for 3 to 6 weeks. If no response is obtained by then, continued administration is unlikely to help. Side Effects The commonly observed adverse events that occurred in Marplan patients with an incidence of 5% or greater and at least twice the incide ...
... Beneficial effects may not be seen in some patients for 3 to 6 weeks. If no response is obtained by then, continued administration is unlikely to help. Side Effects The commonly observed adverse events that occurred in Marplan patients with an incidence of 5% or greater and at least twice the incide ...
Antidepressants - Dr BL Lim Centre for Psychological Wellness
... 1-Least, 3- moderate, 5-most Stephen M. Stahl, M. (2008). Stahl’s Essential Psychopharmacology (3rd ed.). New York, NY: Cambridge University Press. ...
... 1-Least, 3- moderate, 5-most Stephen M. Stahl, M. (2008). Stahl’s Essential Psychopharmacology (3rd ed.). New York, NY: Cambridge University Press. ...
16 Antidepressants
... • Blocks autoreceptors (feedback mechanism) causing increase in release of norepinephrine and serotonin • Blocks 5‐HT2 and 5‐HT3 receptors – hence avoiding several side effects of SSRIs (anxiety, insomnia, agitation, nausea, sexual dysfunction) ...
... • Blocks autoreceptors (feedback mechanism) causing increase in release of norepinephrine and serotonin • Blocks 5‐HT2 and 5‐HT3 receptors – hence avoiding several side effects of SSRIs (anxiety, insomnia, agitation, nausea, sexual dysfunction) ...
Principles of Psychopharmacology in Children And Adolescents
... • RCTs (Cohen et al 2007 n=24, Robb et al 2008 n=131) did not show superiority of sertraline over PBO, CBT; Steiner et al 2007 showed superiority of high dose VPA (500-1500 mg) over low dose VPA (250 mg) • Open label studies (n of 6-28) of clonidine, propranolol, CBZ, citalopram, risperidone, quetia ...
... • RCTs (Cohen et al 2007 n=24, Robb et al 2008 n=131) did not show superiority of sertraline over PBO, CBT; Steiner et al 2007 showed superiority of high dose VPA (500-1500 mg) over low dose VPA (250 mg) • Open label studies (n of 6-28) of clonidine, propranolol, CBZ, citalopram, risperidone, quetia ...
eprint_1_30658_130
... 3- This lipid solubility also causes these drugs to have variable half-lives for example, 4 to 17 hours for imipramine. 4- As a result of their variable first-pass metabolism in the liver, TCAs have low and inconsistent bioavailability. Therefore, the patient s response and plasma levels can be use ...
... 3- This lipid solubility also causes these drugs to have variable half-lives for example, 4 to 17 hours for imipramine. 4- As a result of their variable first-pass metabolism in the liver, TCAs have low and inconsistent bioavailability. Therefore, the patient s response and plasma levels can be use ...
Depression Prescriber Questions Aug 2012
... shivering, sweating, hyperthermia, HTN, tachycardia, nausea, diarrhea ...
... shivering, sweating, hyperthermia, HTN, tachycardia, nausea, diarrhea ...
General Information/How to use this table :
... in a patient with a “normal” or what is termed “wild type” genotype for this particular gene. Conversely, if the patient carries a polymorphism that induces or increases the activity of this enzyme, the active form will be metabolized more rapidly to less active intermediates and the patient will re ...
... in a patient with a “normal” or what is termed “wild type” genotype for this particular gene. Conversely, if the patient carries a polymorphism that induces or increases the activity of this enzyme, the active form will be metabolized more rapidly to less active intermediates and the patient will re ...
ADHD drugs, long
... Reviews 35 (2011):1722-1739. W. Carlezon, “Enduring behavioral effects of early exposure to methylphenidate in rats,” Biological Psychiatry 54 (2003):1330-37; C. Bolanos, “Methylphenidate treatment during pre-and periadolescence alters behavioral responses to emotional stimuli at adulthood,” Biologi ...
... Reviews 35 (2011):1722-1739. W. Carlezon, “Enduring behavioral effects of early exposure to methylphenidate in rats,” Biological Psychiatry 54 (2003):1330-37; C. Bolanos, “Methylphenidate treatment during pre-and periadolescence alters behavioral responses to emotional stimuli at adulthood,” Biologi ...
Antidepressants and suicide
... Reviews 35 (2011):1722-1739. W. Carlezon, “Enduring behavioral effects of early exposure to methylphenidate in rats,” Biological Psychiatry 54 (2003):1330-37; C. Bolanos, “Methylphenidate treatment during pre-and periadolescence alters behavioral responses to emotional stimuli at adulthood,” Biologi ...
... Reviews 35 (2011):1722-1739. W. Carlezon, “Enduring behavioral effects of early exposure to methylphenidate in rats,” Biological Psychiatry 54 (2003):1330-37; C. Bolanos, “Methylphenidate treatment during pre-and periadolescence alters behavioral responses to emotional stimuli at adulthood,” Biologi ...
Antidepressant Choices in Primary Care
... as it causes fewer CNS activating effects. It also has few sexual side effects.9 It carries a black box warning, however, after over 30 cases of severe hepatoxicity occurred worldwide.12 However, the medication has been used in thousands of patients without problems, although patients who are at ris ...
... as it causes fewer CNS activating effects. It also has few sexual side effects.9 It carries a black box warning, however, after over 30 cases of severe hepatoxicity occurred worldwide.12 However, the medication has been used in thousands of patients without problems, although patients who are at ris ...
Psychopharmacology
... The risk of death from suicide, accidents, heart disease, respiratory disorders, and stroke is higher among the depressed. ...
... The risk of death from suicide, accidents, heart disease, respiratory disorders, and stroke is higher among the depressed. ...
Drugs used to Treat Depression
... Prozac, became available for OCD, also treats PTSD, dysphoria, panic disorder, and social phobia • Citalopram (Celexa) – well absorbed orally, few drug interactions, treats major depression, social phobia, panic disorder and OCD ...
... Prozac, became available for OCD, also treats PTSD, dysphoria, panic disorder, and social phobia • Citalopram (Celexa) – well absorbed orally, few drug interactions, treats major depression, social phobia, panic disorder and OCD ...
Practical Psychopharmacology in Children and Adolescents
... Adolescents are much more likely to kill themselves with firearms 12 Children are much more likely to kill themselves by strangulation 12 Ask about suicide and watch for suicidal behavior Monitor and ask about drug/alcohol use Monitoring after starting antidepressant: Weeks 1-4: weekly Weeks ...
... Adolescents are much more likely to kill themselves with firearms 12 Children are much more likely to kill themselves by strangulation 12 Ask about suicide and watch for suicidal behavior Monitor and ask about drug/alcohol use Monitoring after starting antidepressant: Weeks 1-4: weekly Weeks ...
atomoxetine - DavisPlus
... Drug-Drug: Concurrent use with MAO inhibitors may result in serious, potentially fatal reactions (do not use within 2 wk of each other).qrisk of cardiovascular effects with albuterol or vasopressors(use cautiously). Drugs which inhibit the CYP2D6 enzyme pathway (quinidine, fluoxetine, paroxetine) wi ...
... Drug-Drug: Concurrent use with MAO inhibitors may result in serious, potentially fatal reactions (do not use within 2 wk of each other).qrisk of cardiovascular effects with albuterol or vasopressors(use cautiously). Drugs which inhibit the CYP2D6 enzyme pathway (quinidine, fluoxetine, paroxetine) wi ...
see p. Psy15 - Viktor`s Notes for the Neurosurgery Resident
... N.B. each SSRI drug inhibits isoforms (such as 2D6 or 2C19) to different degrees to avoid particular drug interaction, clinicians may choose one SSRI over another 7. Overdoses (high therapeutic index - safer than TCAs!) do not cause cardiac arrhythmias but can cause seizures. 8. Pregnancy concerns: ...
... N.B. each SSRI drug inhibits isoforms (such as 2D6 or 2C19) to different degrees to avoid particular drug interaction, clinicians may choose one SSRI over another 7. Overdoses (high therapeutic index - safer than TCAs!) do not cause cardiac arrhythmias but can cause seizures. 8. Pregnancy concerns: ...
Antidepressants: Update on New Agents and Indications
... Whether patients with PTSD will benefit from long-term treatment with sertraline or a combination of the drug and behavior therapy is presently unknown. The newest indication for sertraline is the treatment of PMDD. Sertraline has been shown to improve quality-oflife scores and psychologic and behav ...
... Whether patients with PTSD will benefit from long-term treatment with sertraline or a combination of the drug and behavior therapy is presently unknown. The newest indication for sertraline is the treatment of PMDD. Sertraline has been shown to improve quality-oflife scores and psychologic and behav ...
Drugs for Depressive Disorders
... Pharmacological effects ➼ All available antidepressants are equally effective in the general depressed patient population. ➼ All antidepressants have the same delayed onset (1-4 weeks) of therapeutic effects. ➼ Some central and many peripheral effects of antidepressants result from blockade of serot ...
... Pharmacological effects ➼ All available antidepressants are equally effective in the general depressed patient population. ➼ All antidepressants have the same delayed onset (1-4 weeks) of therapeutic effects. ➼ Some central and many peripheral effects of antidepressants result from blockade of serot ...
Anti-depressants
... Selective Serotonin and noradrenaline reuptake inhibitor – like amitryptyline. Few other effects – unlike amitryptyline. 75-150mg / day minimum Dry mouth, somnolence, high BP, nausea, headache and dizziness. ...
... Selective Serotonin and noradrenaline reuptake inhibitor – like amitryptyline. Few other effects – unlike amitryptyline. 75-150mg / day minimum Dry mouth, somnolence, high BP, nausea, headache and dizziness. ...
To help with relaxation, mental and physical balance, and maintain
... to be significantly superior over placebo.1 In a clinical double blind study, 30 patients with mild to moderate depression were either treated with 30 mg of saffron (stigma’s extract) or with 100 mg imipramin for 6 weeks: The effects were found to be equivalent, with a better tolerability of saffron ...
... to be significantly superior over placebo.1 In a clinical double blind study, 30 patients with mild to moderate depression were either treated with 30 mg of saffron (stigma’s extract) or with 100 mg imipramin for 6 weeks: The effects were found to be equivalent, with a better tolerability of saffron ...
Affective and Anxiety Disorders
... ◦ antidepressant, anticraving (for nicotine dependence) ◦ antidepressant effect much like the SSRIs but with less nausea, diarrhea, somnolence and sexual dysfunction ◦ selectively inhibits DA, NE reuptake ...
... ◦ antidepressant, anticraving (for nicotine dependence) ◦ antidepressant effect much like the SSRIs but with less nausea, diarrhea, somnolence and sexual dysfunction ◦ selectively inhibits DA, NE reuptake ...
Fluoxetine
Fluoxetine (also known by the trade names Prozac, and Sarafem, among others) is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. Fluoxetine was discovered and developed by scientists from Eli Lilly and Company. It was approved by the U.S. Food and Drug Administration for the treatment of major depressive disorder in December 1987. The U.S. fluoxetine patent expired in August 2001, so generic formulations are now available in the U.S.Fluoxetine is used for the treatment of major depressive disorder (including pediatric depression), obsessive–compulsive disorder (in both adults and children), bulimia nervosa, panic disorder, and premenstrual dysphoric disorder. In addition, it is used to treat trichotillomania if cognitive behaviour therapy has been unsuccessful.In 2010, over 24.4 million prescriptions for generic formulations of fluoxetine were filled in the United States, making it the third-most prescribed antidepressant after sertraline and citalopram. In 2011, 6 million prescriptions for fluoxetine were filled in the United Kingdom. It is on the World Health Organization's List of Essential Medicines, the most important medications needed in a basic health system.