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Slide 1
Slide 1

...  Codon is a 3-nucleotide sequence in mRNA that specifies an amino acid ...
DNA Profiling
DNA Profiling

... • E. coli is a waterborne and foodborne bacteria whose virulence seems to have been increasing • Recent outbreaks have been marked by greater hemolytic uremic syndrome (HUS) • DNA profiling was used to prove newly evolved strains are increasingly deadly Manning, 2008 ...
total point value equals exactly 30
total point value equals exactly 30

... recessive (tt). In the original herd, there are at least 90 T alleles (cause there are 90 elephants with tusks) and at least 20 t alleles (20 non-tusked elephants). Each time a tusked elephant is killed, at least 1 T allele is removed from the population. And each time a non-tusked elephant reproduc ...
Finding the Lost Treasure of NGS Data
Finding the Lost Treasure of NGS Data

... Identification using RNAseq Data • Traditionally, somatic mutations are detected using Sanger sequencing or RT-PCR by comparing paired tumor and normal samples. One obvious limitation of such methods is that we have to limit our search to a certain genomic region of interest. • With the maturity of ...
DNA Technology - 2 What are plasmids?
DNA Technology - 2 What are plasmids?

... They are used to manipulate genes in the lab They are small Contain genes useful to the bacteria And, are easily taken up by bacterial cells ...
Gene Expression Prokaryotes and Viruses
Gene Expression Prokaryotes and Viruses

Nucleic Acid Notes
Nucleic Acid Notes

... PROTEINS- “Cellular toolbox” • Make up 50% or more of dray mass of most cells • Humans have tens of thousands of different proteins • Typical protein = 200-300 amino acids; biggest known = 34,000 • We know the amino acid sequences of > 875,000 proteins/3D shapes of about 7,000 • Scientists use X-ra ...
Powerpoint file - Centre for Microbial Diseases and Immunity
Powerpoint file - Centre for Microbial Diseases and Immunity

... Pathogenomics Goal: Identify previously unrecognized mechanisms of microbial pathogenicity using a unique combination of informatics, evolutionary biology, microbiology and genetics. ...
The Revised Human Genome Attachment STILL DROWNING IN
The Revised Human Genome Attachment STILL DROWNING IN

Genetic Engineering Pros and Cons
Genetic Engineering Pros and Cons

... Genetic Engineering Pros and Cons Definition and Examples Genetic engineering is where a scientist physically changes or modifies the DNA of an organism. This is done to plants, animals, and even humans. The DNA in plants can be changed so they need less water or will grow taller or faster. It can a ...
Phylogenetic analysis
Phylogenetic analysis

Transcription
Transcription

... Converting a gene from the DNA blueprint into a complementary single-stranded RNA sequence ...
Chapter 17 Presentation
Chapter 17 Presentation

... does this information determine the organism’s appearance?  How is the information in the DNA sequence translated by a cell into a specific trait? ...
DNA, RNA, and Protein Synthesis
DNA, RNA, and Protein Synthesis

... few nucleotides are known as point mutations because they occur at a single point in the DNA sequence. • Point mutations include substitutions, insertions, and deletions. ...
Gene Duplication: The Genomic Trade in Spare Parts
Gene Duplication: The Genomic Trade in Spare Parts

... addition, coding sequence changes have co-evolved with the regulatory changes so that the O2 binding affinity of haemoglobin is optimised for each developmental stage. This coupling between coding and regulatory change is similarly noted at a genomic level when expression differences between many dup ...
DNA, Transcription and Translation
DNA, Transcription and Translation

... nucleus. They consist of DNA and therefore, carry the genes. They change shape at various stages of the cell’s life. • The DNA molecule is very long. In a human nucleus of 6μm, the DNA will be 1.8m long. • In eukaryotes the DNA is coiled around proteins called histones. When the DNA is coiled it is ...
RNA & Protein Synthesis
RNA & Protein Synthesis

... • DNA is found in the nucleus of cells, but proteins are built in the cytoplasm. • DNA cannot leave the nucleus, so a copy of the gene is made in the form of a similar nucleic acid called RNA ...
Ch 18 Notes - FacStaff Home Page for CBU
Ch 18 Notes - FacStaff Home Page for CBU

... DNA methylation, the addition of methyl groups to certain bases in DNA, is associated with reduced transcription in some species. DNA methylation can cause long-term inactivation of genes in cellular differentiation. In genomic imprinting, methylation regulates expression of either the maternal or p ...
PPT File
PPT File

... (b) Novel contigs not present in the reference assembly (red) but detected among clone pool–derived reads (light blue, purple, yellow) are anchored by searching for positions in the reference common to those pools but missing from most or all other pools. This approach anchors 1,733 recently reporte ...
Chapter 14: DNA Technologies
Chapter 14: DNA Technologies

... 2. Transgenic animals can produce genetically engineered proteins a) Transgenic animals may be produced by injecting the DNA of interest into a fertilized egg cell or an embryonic stem cell (ES cells) b) Some transgenic animals produce a useful protein that can be extracted from their milk (e.g., sh ...
Genomes and Their Evolution - Phillips Scientific Methods
Genomes and Their Evolution - Phillips Scientific Methods

21_Study Guide
21_Study Guide

... Most bacterial genomes have between 1 and 6 million base pairs (Mb); the genome of E. coli, for instance, has 4.6 Mb. Genomes of archaea are generally within the size range of bacterial genomes. Eukaryotic genomes tend to be larger: The genome of the single-celled yeast S. cerevisiae has about 13 Mb ...
91159 Demonstrate understanding of gene expression
91159 Demonstrate understanding of gene expression

... Biological ideas and processes relating to the determination of phenotype via metabolic pathways are selected from:  biochemical reactions are catalysed by specific enzymes and every enzyme is coded for by a specific gene(s)  biochemical reactions do not occur in isolation but form part of a chain ...
DNA Repair & Recombination
DNA Repair & Recombination

... Strands unwound by helicase. ...
File - Ms. Poole`s Biology
File - Ms. Poole`s Biology

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Molecular evolution

Molecular evolution is a change in the sequence composition of cellular molecules such as DNA, RNA, and proteins across generations. The field of molecular evolution uses principles of evolutionary biology and population genetics to explain patterns in these changes. Major topics in molecular evolution concern the rates and impacts of single nucleotide changes, neutral evolution vs. natural selection, origins of new genes, the genetic nature of complex traits, the genetic basis of speciation, evolution of development, and ways that evolutionary forces influence genomic and phenotypic changes.
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