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Natural history of disease / Population screening
Natural history of disease / Population screening

... (Reuters) - A new analysis of evidence used by a U.S. advisory panel to roll back breast cancer screening guidelines suggests it may have ignored evidence that more frequent mammograms save more lives, U.S. researchers said on Tuesday. ...
Read More... - Indian Chest Society
Read More... - Indian Chest Society

... Historical names of ILD In the nineteenth century, lung fibrosis was called as ‘cirrhosis of the lung’. It was in 1944 that Louis Hamman and Arnold Rich first described pulmonary fibrosis. They reported cases which presented with subacute respiratory failure which lead to death. They performed autop ...
Scleroderma - Daniel Watrous, MD
Scleroderma - Daniel Watrous, MD

... some people with Raynaud's do not have any other disease. This image shows diffuse soft• Skin thickening, swelling and tightening. This is the tissue swelling of the digits, problem that leads to the name "scleroderma" ("Sclera" characteristic of the early means hard and "derma" means skin). The ski ...
6 Infectious Bursal Disease
6 Infectious Bursal Disease

... poultry producing area (148, 154). These strains were breaking through maternal immunity against “standard” strains, and they also differed from standard strains in their biological properties (152, 153). These variants, or subtypes, were either already present in nature but unrecognized or were new ...
Wild and Domestic Pig Interactions at the Wildlife–Livestock
Wild and Domestic Pig Interactions at the Wildlife–Livestock

... escalated due to the expansion of human population and subsequent encroachment into wildlife habitats (2). Indeed, human population growth is expected to reach nine million people by 2050 (3), leading to an ever-increasing request of animal protein (4, 5), consequent continuation of agricultural lan ...
Case-control Study of Armadillo Contact and Hansen`s Disease
Case-control Study of Armadillo Contact and Hansen`s Disease

... at TCID and not an attempt to compare the two mycobacterial diseases. Routine clinical care was determined by the treating physician and was not influenced by participation in the study. A comprehensive questionnaire was administered to all study participants in either English or Spanish, depending ...
Therapeutic Goals in the Treatment of Gaucher Disease
Therapeutic Goals in the Treatment of Gaucher Disease

... lengthy periods of quiescence lasting for months or even many years. Furthermore, for each patient, disease severity may be unevenly distributed according to organ compartments. For example, some patients suffer primarily from the effects of splenic enlargement, often but not invariably accompanied ...
Consensus statement on the revised World Health Organization
Consensus statement on the revised World Health Organization

... low perceived risk of serious adverse events.6 Identification of HIV infection at birth, when BCG is often administered, is not, however, possible in the vast majority of infants, as most HIV transmission in developing counties occurs peri- or postpartum and HIVinfected infants are usually not sympt ...
PDF - Centre For Public Scrutiny
PDF - Centre For Public Scrutiny

... Immunisation is a proven tool for controlling and eliminating infectious diseases and the World Health Organisation (WHO) have estimated it to avert between two and three million deaths globally each year. 3 The primary aim of vaccination is to protect the individual. However, because vaccinated ind ...
Non-Communicable Diseases Watch Volume 3 Number 10 (Oct 2010)
Non-Communicable Diseases Watch Volume 3 Number 10 (Oct 2010)

... characterised by a persistent blockage of airflow from the lungs that cannot be fully reversed. It is a major cause of mortality and morbidity throughout the world. According to 2007 World Health Organization (WHO) estimates, as many as 210 million people around the world have the disease. In 2005, ...
The 30-Year War on AIDS: Have We Reached the Tipping Point?
The 30-Year War on AIDS: Have We Reached the Tipping Point?

... of opportunistic infections and unusual rare tumors alerted public health officials of a new disease that eventually become known as the AIDS. Over the ensuing year, similar opportunistic infections were reported in persons with hemophilia A, recipients of blood transfusions, injecting drug users, a ...
Anthrax, Botulism, Smallpox, Plague
Anthrax, Botulism, Smallpox, Plague

... "The tricky piece is that many biologic agents can be used, and the initial presenting symptoms are very parallel to other on-going ailments," Johnson said. One of the keys is spotting unusual signs, "to notice if there is something specific in the presenting characteristics of the individual." Seco ...
Tuberculosis Of The Musculoskeletal System
Tuberculosis Of The Musculoskeletal System

... Antitubercular drugs have been grouped into first and second line agents.5,67,69 First line agents include Isoniazid, Rifampicin, Streptomycin, Pyrazinamide, Ethambutol, and Thiocetazone. Second line agents Capreomycin, Kanamycin, Ethionamide, Cycloserine, and Paraamino-salicylic acid. These agents ...
A Population Model of Malaria Transmission According to Within
A Population Model of Malaria Transmission According to Within

... Malaria is a vector-borne infectious disease which is caused by protozoan parasites. Symptoms are characterized by high fever, chills, u-like symptoms, and in many cases, death. Malaria shares many characteristics with other protozoan parasites, which cause diseases such as African trypanosomiasis ...
phenomenological study of backward bifurcation in epidemiological
phenomenological study of backward bifurcation in epidemiological

... SI model in [6], Huang et al considered a multi-group model for dynamics o f HIV/AIDS transmission in [11]. Backward bifurcation of endemic equilibria occurs as a result of the incorporation of several groups of susceptible, or infective In terms of disease control, merely reducing the reproduction ...
Unit 2: HIV Clinical Staging and Surveillance Case Definitions
Unit 2: HIV Clinical Staging and Surveillance Case Definitions

... who will establish and monitor the HIV case surveillance system  adopt standardised HIV surveillance case definitions  conduct rapid assessment/evaluation to determine the current status of the AIDS case reporting system  work with appropriate staff to incorporate the elements of the case definit ...
CompleteSummaryH5N1Others26thDecemberFormated
CompleteSummaryH5N1Others26thDecemberFormated

... H5N1 is widespread in Vietnam where 70-80% of ducks in the Mekong Delta are infected. An outbreak in Quang Nam province in central Vietnam reported 11th November killed 300 ducks. In Vietnam outbreaks were reported in 17 of the 64 provinces. In December outbreaks occurred in the northern provinces o ...
Crimean-Congo Hemorrhagic Fever
Crimean-Congo Hemorrhagic Fever

... countries in Africa, Asia, South-East Europe, and the Middle East. The majority of human cases are workers in livestock industry, agriculture, slaughterhouses, and veterinary practice. Nosocomial transmission is also well described. Clinical manifestations are nonspecific and symptoms typically incl ...
Ebola virus disease (EVD): Updated information for health
Ebola virus disease (EVD): Updated information for health

... haemorrhagic fever caused by filoviruses (Ebola and Marburg viruses) ................................ 12 ...
Pneumococcal Vaccination Status for Older Adults
Pneumococcal Vaccination Status for Older Adults

... pneumococcal infection in adults; in the United States there are an estimated 900,000 cases each year and a 5 percent–7 percent mortality rate (CDC, 2015). Pneumococcal infection accounts for more deaths than any other vaccine-preventable bacterial disease (CDC, 1997). Pneumococcal pneumonia account ...
Scientific dogmas, paradoxes and mysteries of latent
Scientific dogmas, paradoxes and mysteries of latent

... accurate study to survey worldwide prevalence of latent TB would be impossible due to logistical reasons. Thus epidemiological models based on sets of complex formulae, using epidemiological indicators of case notification rates, predicted incidence of disease, mortality from TB, annual risk of infe ...
Myths and concerns about vaccination
Myths and concerns about vaccination

... compound, methyl mercury, a known neurotoxin. Thiomersal has been used in very small amounts in vaccines for about 80 years with no evidence of it being harmful. Thiomersal is discussed further in the section ‘Safety concerns: General’. Antibiotics, such as neomycin and polymyxin B, are used in some ...
Neutropenia Febril
Neutropenia Febril

... Von Eiff, et al. Respiration 1995; 62: 241-7 ...
Final Protocol - Word 730 KB - Medical Services Advisory Committee
Final Protocol - Word 730 KB - Medical Services Advisory Committee

... to investigate patients with suspected complications from small bowel Crohn’s disease. MRI is reported to be much more accurate than SBFT but similar in sensitivity and specificity to CT and avoids the radiation risk associated with these tests (American College of Radiology 2011). A further advanta ...
Infection prevention in points of dispensing
Infection prevention in points of dispensing

... that provide easy access to a large portion of the population.4 Communities will likely need multiple PODs, especially in more densely populated areas. Although it is preferable to have only healthy individuals visit PODs to pick up medication and/or vaccination for themselves or their family, many ...
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Eradication of infectious diseases



Eradication is the reduction of an infectious disease's prevalence in the global host population to zero. It is sometimes confused with elimination, which describes either the reduction of an infectious disease's prevalence in a regional population to zero, or the reduction of the global prevalence to a negligible amount. Further confusion arises from the use of the term eradication to refer to the total removal of a given pathogen from an individual (also known as clearance of an infection), particularly in the context of HIV and certain other viruses where such cures are sought.Selection of infectious diseases for eradication is based on rigorous criteria, as both biological and technical features determine whether a pathogenic organism is (at least potentially) eradicable. The targeted organism must not have a non-human reservoir (or, in the case of animal diseases, the infection reservoir must be an easily identifiable species, as in the case of rinderpest), and/or amplify in the environment. This implies that sufficient information on the life cycle and transmission dynamics is available at the time an eradication initiative is programmed. An efficient and practical intervention (e.g., a vaccine or antibiotic) must be available to interrupt transmission of the infective agent. Studies of measles in the pre-vaccination era led to the concept of the Critical community size, the size of the population below which a pathogen ceases to circulate. Use of vaccination programmes before the introduction of an eradication campaign can reduce the susceptible population. The disease to be eradicated should be clearly identifiable, and an accurate diagnostic tool should exist. Economic considerations, as well as societal and political support and commitment, are other crucial factors that determine eradication feasibility.Eight attempts have been made to date to eradicate infectious diseases: two successful programs targeting smallpox and rinderpest; four ongoing programs targeting poliomyelitis, yaws, dracunculiasis and malaria; and two former programs targeting hookworm and yellow fever. Five more infectious diseases have been identified as of April 2008 as potentially eradicable with current technology by the Carter Center International Task Force for Disease Eradication—measles, mumps, rubella, lymphatic filariasis and cysticercosis.
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