EFFECT OF VARIOUS ENVIRONMENTAL /PROCESSING FACTORS ON STABILITY OF THE FORMULATION AND
... The effect of some processing and formulation variables on the stability of tablets containing a crystalline salt of a triazine derivative was studied. The salt has a relatively low melting point and a low microenvironmental pH due to the weakly basic nature of the parent compound (pKa = 4.0). This ...
... The effect of some processing and formulation variables on the stability of tablets containing a crystalline salt of a triazine derivative was studied. The salt has a relatively low melting point and a low microenvironmental pH due to the weakly basic nature of the parent compound (pKa = 4.0). This ...
Aalborg Universitet
... It is obvious that the use of pharmaceuticals is only acceptable if no side effects occur. Additionally, medical products are accepted if their side effects are tolerable when compared to the benefits associated with their use. In order to avoid safety problems, drugs must undergo a thorough approva ...
... It is obvious that the use of pharmaceuticals is only acceptable if no side effects occur. Additionally, medical products are accepted if their side effects are tolerable when compared to the benefits associated with their use. In order to avoid safety problems, drugs must undergo a thorough approva ...
Clinical pharmacology of facilities used at the diseases of
... B. Ventricular premature depolarizations C. *Angina pectoris prophylaxis D. Conversion of atrial fibrillation to sinus rhythm E. Treatment of ventricular fibrillation 10. When quinidine is administered to a patieny with atrial fibrilation A. the ventricular rate may increase dangerously B. arterial ...
... B. Ventricular premature depolarizations C. *Angina pectoris prophylaxis D. Conversion of atrial fibrillation to sinus rhythm E. Treatment of ventricular fibrillation 10. When quinidine is administered to a patieny with atrial fibrilation A. the ventricular rate may increase dangerously B. arterial ...
(acts directly to convert plasminogen into plasmin).
... • Anisoylated plasminogen-streptokinase activator complex • Is a complex of purified human plasminogen + bacterial streptokinase that rendered inactive by introducing anisoyl group at its active site. • It is a prodrug, de-acylated in circulation into the active plasminogen-streptokinase complex (ac ...
... • Anisoylated plasminogen-streptokinase activator complex • Is a complex of purified human plasminogen + bacterial streptokinase that rendered inactive by introducing anisoyl group at its active site. • It is a prodrug, de-acylated in circulation into the active plasminogen-streptokinase complex (ac ...
Metabolic Disorders - Pipeline Review, H1 2013 Brochure
... Number of Products Under Development for Metabolic Disorders, H1 2013 16 Products under Development for Metabolic Disorders – Comparative Analysis, H1 2013 17 Number of Products under Development by Companies, H1 2013 19 Number of Products under Development by Companies, H1 2013 (Contd..1) 20 Number ...
... Number of Products Under Development for Metabolic Disorders, H1 2013 16 Products under Development for Metabolic Disorders – Comparative Analysis, H1 2013 17 Number of Products under Development by Companies, H1 2013 19 Number of Products under Development by Companies, H1 2013 (Contd..1) 20 Number ...
1
... acute lymphoblastic leukemia who require L-asparaginase in their treatment regimen, but are hypersensitive to the native forms of L-asparaginase. PEG modified liposomes containing doxorubicin are indicated for patients with AIDS-related advanced Kaposi’s sarcoma [18]. Macromolecular therapeutics has ...
... acute lymphoblastic leukemia who require L-asparaginase in their treatment regimen, but are hypersensitive to the native forms of L-asparaginase. PEG modified liposomes containing doxorubicin are indicated for patients with AIDS-related advanced Kaposi’s sarcoma [18]. Macromolecular therapeutics has ...
Pharma. MCQs
... The mechanism underlying the resistance of G +ve organisms to macrolides is:: a. Decreased drug permeability of the cytoplasmic membrane. b. Methylation of binding sites on the 50-S ribosomal subunit. c. Decreased activity of uptake mechanism. d. Formation of estrases that hydrolyze the lactone ring ...
... The mechanism underlying the resistance of G +ve organisms to macrolides is:: a. Decreased drug permeability of the cytoplasmic membrane. b. Methylation of binding sites on the 50-S ribosomal subunit. c. Decreased activity of uptake mechanism. d. Formation of estrases that hydrolyze the lactone ring ...
4/7/2014 Lab Results Financial disclosure Follow Up Lab Tests
... • No established FDA-approved test to directly measure any of these drug levels ...
... • No established FDA-approved test to directly measure any of these drug levels ...
4 Proposal BSc Programme in pharmacology (Final).
... The normal duration for the Bachelor’s Degree in Pharmacology is four academic sessions of eight semesters while the maximum period shall be 50% above the number of academic session. To be eligible for the award of a Bachelor of Science Degree, a student must obtain a minimum of 90 Credit Units in t ...
... The normal duration for the Bachelor’s Degree in Pharmacology is four academic sessions of eight semesters while the maximum period shall be 50% above the number of academic session. To be eligible for the award of a Bachelor of Science Degree, a student must obtain a minimum of 90 Credit Units in t ...
Prescribing of COX-2 inhibitors in Germany after safety warnings
... new, innovative and more expensive drugs were calculated. Finally, prescribing of relevant drug classes by different medical specialist groups was analysed in order to assess the potential for pharmaceutical interventions. Thus, pharmacists may improve patient safety when different prescribers are n ...
... new, innovative and more expensive drugs were calculated. Finally, prescribing of relevant drug classes by different medical specialist groups was analysed in order to assess the potential for pharmaceutical interventions. Thus, pharmacists may improve patient safety when different prescribers are n ...
Group 1 - Random Sampling
... The route of administration is the path by which a drug is presented to the body. It affects the latency and duration of the drug action. The different routes have its own advantages and disadvantages. Oral route is convenient but the response may be slowed down by food and increased peristalsis. Re ...
... The route of administration is the path by which a drug is presented to the body. It affects the latency and duration of the drug action. The different routes have its own advantages and disadvantages. Oral route is convenient but the response may be slowed down by food and increased peristalsis. Re ...
O A RIGINAL
... results, azathioprinein in diabetic patients spatially in high dose, cause liver damage and using this drug should be restricted. Key words: diabetes, azathioprine, kidney. Introduction In developing countries, one of the major problems in diabetic nephropathy and progressive renal failure is the en ...
... results, azathioprinein in diabetic patients spatially in high dose, cause liver damage and using this drug should be restricted. Key words: diabetes, azathioprine, kidney. Introduction In developing countries, one of the major problems in diabetic nephropathy and progressive renal failure is the en ...
One drug trial, six men, disaster… - Direct-MS
... overall T-cell numbers 20-fold. Similar results were seen in rabbits and monkeys, the company says. Two out of 20 monkeys had swollen lymph nodes, indicating that extra T-cells were being produced as expected, but there was no suggestion of the violent reaction seen in the six men. It was this boost ...
... overall T-cell numbers 20-fold. Similar results were seen in rabbits and monkeys, the company says. Two out of 20 monkeys had swollen lymph nodes, indicating that extra T-cells were being produced as expected, but there was no suggestion of the violent reaction seen in the six men. It was this boost ...
Prednisone Suspension 5mg/mL
... Ora-Blend is similar. When stability studies exist for both vehicles, these products can be considered interchangeable with the benefit of strengthening the supply chain in case of back order of one or the other or when the presence of dyes is of concern. This article addresses the stability of pred ...
... Ora-Blend is similar. When stability studies exist for both vehicles, these products can be considered interchangeable with the benefit of strengthening the supply chain in case of back order of one or the other or when the presence of dyes is of concern. This article addresses the stability of pred ...
Pharmacogenetics and Individualized Drug Therapy
... infection were significantly lower in EMs than in hetEMs and PMs (35–41). Most treatment failures were observed in EMs. In one study (41), clear genotype-related differences were observed in the PPI concentrations at the end of the dose interval (PM, 753 ng/ml; hetEM, 59; EM, 21). Multivariate analy ...
... infection were significantly lower in EMs than in hetEMs and PMs (35–41). Most treatment failures were observed in EMs. In one study (41), clear genotype-related differences were observed in the PPI concentrations at the end of the dose interval (PM, 753 ng/ml; hetEM, 59; EM, 21). Multivariate analy ...
Report on New Patented Drugs — Olmetec Application of the
... The publication of Summary Reports is part of the PMPRB’s commitment to make its price review process more transparent. Where comparators and dosage regimens are referred to in the Summary Reports, they have been selected by the HDAP for the purpose of carrying out the PMPRB’s regulatory mandate, wh ...
... The publication of Summary Reports is part of the PMPRB’s commitment to make its price review process more transparent. Where comparators and dosage regimens are referred to in the Summary Reports, they have been selected by the HDAP for the purpose of carrying out the PMPRB’s regulatory mandate, wh ...
Some drugs can cause taste disturbances
... Some drugs can cause taste disturbances ...leading to loss of appetite and noncompliance. Some of the most common culprits are surprising. Lunesta causes a metallic aftertaste in up to one-third of patients...especially at higher doses. If patients complain, lower the dose or switch to another sleep ...
... Some drugs can cause taste disturbances ...leading to loss of appetite and noncompliance. Some of the most common culprits are surprising. Lunesta causes a metallic aftertaste in up to one-third of patients...especially at higher doses. If patients complain, lower the dose or switch to another sleep ...
PROPUESTA DE SIMPOSIO – AACC 2013 Título: “ALCOHOL USE
... Resumen: The analysis of the relationship existing between alcohol and early ontogeny is commonly undertaken through two substantial problems that affect society as a whole. These problems are: i) teratogenic properties of the drug that define the first congenital cause of mental retardation in west ...
... Resumen: The analysis of the relationship existing between alcohol and early ontogeny is commonly undertaken through two substantial problems that affect society as a whole. These problems are: i) teratogenic properties of the drug that define the first congenital cause of mental retardation in west ...
0316065.01 - Society of Nuclear Medicine
... its target tissue by a monoclonal antibody. “Because of the specific requirements associated with delivery of radioactive isotope therapy, any product containing a therapeutic radioisotope will be considered under the category of benefits described under Section 1861(s)(4) as a therapy.” Id. CMS the ...
... its target tissue by a monoclonal antibody. “Because of the specific requirements associated with delivery of radioactive isotope therapy, any product containing a therapeutic radioisotope will be considered under the category of benefits described under Section 1861(s)(4) as a therapy.” Id. CMS the ...
Long Term Study of Ritalin
... conducted by Charac, et al., from the Hospital for Sick Children in Toronto. Their article nicely summarizes what is currently known about the long term side effects (both mental and physical): "In addition to unanswered questions about the long-term benefits of chronic stimulant use, questions rema ...
... conducted by Charac, et al., from the Hospital for Sick Children in Toronto. Their article nicely summarizes what is currently known about the long term side effects (both mental and physical): "In addition to unanswered questions about the long-term benefits of chronic stimulant use, questions rema ...
ppt - Chair of Computational Biology
... Setup of substace libraries for the High Thoughput Screening (IV) Synthesis of a multitude of compounds based on a lead compounds required a change in paradigms. Until the late 80‘ substances selected for screening were synthesized one by one individually. The principles of High Troughput Screening ...
... Setup of substace libraries for the High Thoughput Screening (IV) Synthesis of a multitude of compounds based on a lead compounds required a change in paradigms. Until the late 80‘ substances selected for screening were synthesized one by one individually. The principles of High Troughput Screening ...
Control Mechanisms of the GI Tract
... • Are the most common complains in vet. medicine • Underlying causes include: – Infectious sources • Gram negative bacterial endotoxin increases b.v. permeability, increased fluid loss ...
... • Are the most common complains in vet. medicine • Underlying causes include: – Infectious sources • Gram negative bacterial endotoxin increases b.v. permeability, increased fluid loss ...
OPIATES, METHADONE, ALCOHOL, BARBITURATES
... morphine and since it takes a little while to come on, the user might turn blue some minutes after injection rather than then and there. If you must use them then crush them and snort them – slowly. Only recently they were removed from the US market because combining these capsules with alcohol coul ...
... morphine and since it takes a little while to come on, the user might turn blue some minutes after injection rather than then and there. If you must use them then crush them and snort them – slowly. Only recently they were removed from the US market because combining these capsules with alcohol coul ...
Development of Tamper Deterrent Formulations
... have conducted numerous in vitro tests simulating abusers techniques such as crushing and solvent extraction and some of the outcomes of these tests were made public during FDA advisory committee meetings and conference presentations. However, little is known about the details of each manufacturer’s ...
... have conducted numerous in vitro tests simulating abusers techniques such as crushing and solvent extraction and some of the outcomes of these tests were made public during FDA advisory committee meetings and conference presentations. However, little is known about the details of each manufacturer’s ...
Pharmacognosy
Pharmacognosy is the study of medicinal drugs derived from plants or other natural sources. The American Society of Pharmacognosy defines pharmacognosy as ""the study of the physical, chemical, biochemical and biological properties of drugs, drug substances or potential drugs or drug substances of natural origin as well as the search for new drugs from natural sources.""It is also defined as the study of crude drugs.