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Fluoroquinolone resistance in mycobacterium tuberculosis strains
Fluoroquinolone resistance in mycobacterium tuberculosis strains

... are also added to the regimen based on first-line DST results 5, 6. In Kenya flouroquinolones are used in the treatment of MDR-TB patients according to WHO standards and are also used in the treatment of other bacterial infections. Treatment of MDR-TB takes 18 to 24 months and must be done on the b ...
  DEVELOPMENT AND EVALUATION OF MUCOADHESIVE BUCCAL TABLETS OF SALBUTAMOL  SULPHATE Research Article
  DEVELOPMENT AND EVALUATION OF MUCOADHESIVE BUCCAL TABLETS OF SALBUTAMOL  SULPHATE Research Article

... In vitro bioadhesion studies show that tablet containing HPMC K‐4M  & EC (2:1 ratio) has maximum bioadhesive strength, it means HPMC  K‐4M has more bioadhesive property than EC.  An  ideal  controlled  release  system  should  release  the  drug  immediately to attain the required therapeutic level, ...
this publication - G
this publication - G

... The binding was determined by conductometric and UV-spectrophotometric methods on the instrument U3000 Spectrophotometer (λ = 204 nm) (Hitachi). Samples of the solutions were passed through Sephadex column (Sigma Chemical Co. DE-52) to separate the polymer from drug and washed with ethanol: water in ...
Enhancement of Dissolution Rate of Ritonavir: A Comparative
Enhancement of Dissolution Rate of Ritonavir: A Comparative

... decreased with increasing carrier concentration, demonstrating that the reaction became more favorable as the concentration of carrier increased. In vitro Dissolution Studies: All formulations of Ritonavir were subjected to in vitro dissolution studies using 0.1N HCl as the dissolution medium to ass ...
Public Assessment Report Irbesartan Elpen 75 mg, 150 mg, 300 mg
Public Assessment Report Irbesartan Elpen 75 mg, 150 mg, 300 mg

...  they are going to have an operation (surgery or be given anaesthetics;  they are taking any of the following medicines used to treat high blood pressure: o an ACE-inhibitor ( for example enalapril, lisinopril, ramipril) in particular if having diabetes-related kidney problems, o aliskiren. The do ...
Principles of Clinical Trials Introduction and Learning Objectives
Principles of Clinical Trials Introduction and Learning Objectives

... Dagher R et al. In: Gad SC. Clinical Trials Handbook. John Wiley & Sons, Inc.; 2009:1153–1171. Gray B et al. Health Aff. 2012;31:140–149. Holford N et al. Clin Pharmacol Ther. 2010;88:166–182. Husereau D et al. Clin Ther. 2013;35:356–363. Nedelman J et al. In: Gad SC. Clinical Trials Handbook. John ...
DrugFacts MDMA 2013
DrugFacts MDMA 2013

... psychotherapy—although  without  the   support  of  clinical  trial  research  or  FDA   approval.  In  1985,  the  Drug  Enforce-­‐ ment  Administration  labeled  MDMA  a   Schedule  I  substance,  or  a  drug  with   high  abuse  potential ...
Slide 1
Slide 1

... domestic spoons are used by patients, prescribers ignore this diversity by reducing it to 3 sizes only. (5) Although pediatricians have a good knowledge of domestic spoon capacities, many GPs and most of the pharmacists overestimate them, leading to underdosage for adults, especially in cough prepar ...
Antipsychotics
Antipsychotics

... used as pre-anesthetic medication, but quickly were adopted by psychiatrists to calm down their mental patients. ...
Viktor`s Notes * Drug-Induced Movement Disorders
Viktor`s Notes * Drug-Induced Movement Disorders

... NEUROLEPTIC MALIGNANT SYNDROME  PREVALENCE (among patients receiving neuroleptics) < 2%; most commonly young adults.  pathogenesis is not completely understood (believed to be blockade of D2 receptors).  associated with all groups of neuroleptics (esp. high-potency agents [HALOPERIDOL, FLUPHENAZI ...
GDP Regimen - Cancer Care Ontario
GDP Regimen - Cancer Care Ontario

... information (for health professionals) contained in the Drug Formulary (the "Formulary") is intended for healthcare providers and is to be used for informational purposes only. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects o ...
Extraction of Paris polyphylla Rhizome Using
Extraction of Paris polyphylla Rhizome Using

... Keywords: Paris polyphylla; Rhizoma Paridis; Phytochemicals INTRODUCTION Medicinal plants have been used from ancient days for treating diverse varieties of ailments. Plants produce number of chemical compounds for biological functions and defence mechanisms. In modern medicine, these active phytoch ...
Meeting Report: Technical Definitions of Shortages and Stockouts of
Meeting Report: Technical Definitions of Shortages and Stockouts of

... blamed and penalized for a stockout that they report, adversely affecting their motivation to make accurate reports of shortages and stockouts. Another example was reporting among wholesale pharmacy distributors that was intended to promote information sharing, but instead led to hoarding of product ...
4 2. LITERATURE REVIEW: Ariyana, et al (2014), developed
4 2. LITERATURE REVIEW: Ariyana, et al (2014), developed

... pseudoplastic behaviour. It was stated that ofloxacin gels along with scaling and root planning results in significant benefits in the treatment of periodontitis. 35 Baksh A, et al (2012), reported formulation and in vitro evaluation of NSAID’s gel. In this study transdermal permeation of Diclofenac ...
Current Concepts in Antiretroviral Therapy Failure - IAS-USA
Current Concepts in Antiretroviral Therapy Failure - IAS-USA

... As discussed above, the goal of a second regimen should continue to be to achieve virologic suppression to less than 50 copies/mL of plasma HIV-1 RNA. When available, resistance testing should guide the choice of drugs in the new regimen; when resistance testing is not available, knowledge of common ...
`False-positive` and `false-negative` test results in clinical urine drug
`False-positive` and `false-negative` test results in clinical urine drug

... has set a threshold of 15,000 µg/l, above which poppy seed administration cannot be accepted as a valid explanation for an opiate-positive drug test [13] . There is evidence, however, that poppy seed-related total urine morphine concentrations can exceed this threshold [6] . ...
CIELAP – There is No "AWAY" - Canadian Institute for
CIELAP – There is No "AWAY" - Canadian Institute for

... susceptible strains of bacteria is known as antimicrobial resistance, or AMR. However, the very low concentrations of antibiotics found in surface or drinking water probably do not cause the development of AMR specifically from those drug residues in that water. Concerns regarding AMR in the environ ...
PHT 415 student Handout 3031
PHT 415 student Handout 3031

... semilog paper. The slope is equal to –k/2.3. The value for k a can be obtained by using the method of residuals or a feathering technique as following: 1. Plot the drug concentration versus time on semilog paper with the concentration values on the logarithmic axis. 2. Obtain the slope of the termin ...
International Journal for Pharmaceutical Research Scholars (IJPRS)
International Journal for Pharmaceutical Research Scholars (IJPRS)

... Extended release system are considered a wiser approach for the drugs with short half-lives and which require repeated dosing, they are easy to formulate and are irrespective of absorption process from gastrointestinal tract after oral administration. KEYWORDS Extended Release Dosage Forms, Half-lif ...
Access to cannabis for medical and scientific purposes RIS
Access to cannabis for medical and scientific purposes RIS

... states and territories exploring options to provide access to cannabis for specified conditions through clinical trials or other authorised mechanisms. The Australian Government has made a commitment to work collaboratively with the States and Territories to share knowledge and information on issues ...
GUIDANCE TO SURVEYORS - LONG TERM CARE FACILITIES
GUIDANCE TO SURVEYORS - LONG TERM CARE FACILITIES

... will, or the will of the resident’s legal representative. Emergency or short term monitored separation from other Residents will not be considered involuntary seclusion and may be permitted if used for a limited period of time as a therapeutic intervention to reduce agitation until professional staf ...
Glossary of Lung Cancer Clinical Trial Terms
Glossary of Lung Cancer Clinical Trial Terms

... Chemotherapy is a systemic treatment, which means it flows through the bloodstream, reaching every part of the body. Clinical investigator A medical researcher who helps carry out a clinical trial. Clinical trial A research study that attempts to answer specific questions about new therapies or new ...
Bariatric surgery patients and their medicines
Bariatric surgery patients and their medicines

... The NICE CG43 on obesity recommended bariatric surgery as a treatment option for adults and children with a BMI of 40kg/m2 and as a first-line option for adults with a BMI > 50kg/m2 in whom surgical intervention is considered appropriate.2 However, the NHS England policy for commissioning complex an ...
Mass versus molar doses, similarities and
Mass versus molar doses, similarities and

... carboxylic acids, which are antagonists of peroxisome proliferator-activated receptor (PPAR-alpha). Pharmacologically, fibrates belongs to of lipid-modifying agents. Treatment with fibrates results in a substantial decrease in plasma levels of triglycerides and is usually associated with a moderate ...
hydromorphone
hydromorphone

... does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare pr ...
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Pharmacognosy



Pharmacognosy is the study of medicinal drugs derived from plants or other natural sources. The American Society of Pharmacognosy defines pharmacognosy as ""the study of the physical, chemical, biochemical and biological properties of drugs, drug substances or potential drugs or drug substances of natural origin as well as the search for new drugs from natural sources.""It is also defined as the study of crude drugs.
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