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multiple-choice tests in pharmacology
multiple-choice tests in pharmacology

... a) Information about main mechanisms of drug absorption b) Information about unwanted effects c) Information about biological barriers d) Information about excretion of a drug from the organism 004. Pick out the answer which is the most appropriate to the term “receptor” a) All types of ion channels ...
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Ian Martin Slides PDF

... ∆HDO ∆cLogP ...
View SPC - Veterinary Medicines Directorate
View SPC - Veterinary Medicines Directorate

... The mode of action is believed to act like salicylanilides by interfering with oxidative phosphorylation. Affected tapeworms are dislodged and disintegrate during their passage along the alimentary tract so they are not easily recognisable when passed 6-8 hours after dosing. Piperazine Phosphate BP: ...
INT_CAT_NGO_RUS_13012_E
INT_CAT_NGO_RUS_13012_E

... About 37.2% of injecting drug users who live in Russia are living with HIV,11 and in some regions HIV prevalence in this group reaches 75%.12 According to the official data, about 80% of HIV cases from 1987 to 2008 were related to injecting drug use.13 For 59.2% of HIV positive people identified in ...
Influence of CYP2D6 genotype on the
Influence of CYP2D6 genotype on the

... enzyme CYP2D6 to the active metabolite O-desmethylvenlafaxine (ODV). VEN is also metabolized to N-desmetylvenlafaxine (NDV) via CYP3A4. ODV and NDV are further metabolized to N,Odidesmethylvenlafaxine (DDV). VEN is a racemic mixture of the S- and R-enantiomers and these have in vitro displayed diffe ...


... A lead SN-38 HDC for which detailed evaluations has been done showed that the payload is released in tumor for a prolonged period of time (0.22uM and 0.38uM at 24h and72h respectively in tumor against 30nM at 24h and no drug quantified at 72h for irinotecan, at their maximum tolerated doses (MTDs). ...
which is a tamper resistant er/la opioid?
which is a tamper resistant er/la opioid?

... in a position to know if any pills are missing • Take note of how many pills are in each prescription bottle or pill packet • Keep track of your refills for your own medication, as well as for other members of the household • Make sure friends and relatives— especially grandparents—are aware of the ...
OF HEALTH  &  HUMAN  SERVICES Ms. Anna Tucci
OF HEALTH & HUMAN SERVICES Ms. Anna Tucci

... that section may not claim to diagnose,mitigate, treat, cure, or prevent a specific diseaseor class of diseases.The claim that these products or their ingredients impart “antiseptic” properties suggeststhat theseproducts are intended, in part, to treat, prevent, or mitigate disease,namely, diseasesc ...
Ephedra PowerPoint
Ephedra PowerPoint

... July 2008 Final Rule: “… dietary supplements that contain ephedrine alkaloids are adulterated under section 402(f)(1)(A) of the Federal Food, Drug, and Cosmetic Act (21 U.S.C. 342(f)(1)(A)). It is illegal to market an adulterated dietary supplement.” ...
FABRICATION, EVALUATION AND PRELIMINARY CLINICAL STUDY OF BI-LAYER OROBUCCAL
FABRICATION, EVALUATION AND PRELIMINARY CLINICAL STUDY OF BI-LAYER OROBUCCAL

... bacterial plaque and calculus. However, as specific bacteria are thought to play a major role in the disease process [5], antimicrobial agents have also been used as adjuncts to mechanical treatment, particularly in treating early-onset and refractory cases [6]. The potential side-effects in adminis ...
PLGA-Alendronate Conjugate as a New Biomaterial
PLGA-Alendronate Conjugate as a New Biomaterial

... many obstacles must be overcome. Bones are covered with lining cells acting as a marrowblood barrier; therefore, the contact of exogenous compounds to the bone surface is restricted. Furthermore, the expression of biomolecules having a specific targets, like enzymes or antigens is relatively low in ...
Surrogate Endpoints: A Regulatory View
Surrogate Endpoints: A Regulatory View

... In short, it could be directly in the causal ...
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... Natural products are an important source of new structures leading  to  drugs  in  all  major  disease  areas.  They  represent  a  pool  of  privileged  structures  that  are  optimized  by  evolution  to  interact  with  proteins  and  other  molecules[1].  The  starting  materials  for  about  on ...
Fact Sheet (2002) Amphetamine and Ecstasy Use in the Caribbean
Fact Sheet (2002) Amphetamine and Ecstasy Use in the Caribbean

... activity leading to an increase in physical activity, heart rate, blood pressure and body temperature and decreased appetite. They cause feeling of euphoria, wellbeing and confidence in users. Similar to amphetamines, the sought-after effects of ecstasy are increased physical energy. In addition, us ...
amphetamines and other stimulants history
amphetamines and other stimulants history

... Every drug in the amphetamine group is a psychostimulant (a drug that increases the activity of the brain). Unlike many other frequently abused drugs, amphetamines are not natural, but can only be made in a chemical laboratory (Lukas, 1989, p. 9). Amphetamines were originally made in 1887 by a Germa ...
anti-inflammatory screening of jatropha curcas root, stem and leaf in
anti-inflammatory screening of jatropha curcas root, stem and leaf in

... 1976; Nadkarni, 1976; Agarwal, 1986; Ambasta, 1986). Recently, based on ethnobotanical practice the root extract of this plant was investigated for antidiarrheal activity in albino mice. The proposed mechanism of action was through a combination of inhibition of elevated prostaglandin biosynthesis a ...
Oral Hypoglycemic Agents
Oral Hypoglycemic Agents

... Oral hypoglycemic agents Biguanides  Sulfonylureas  α- glucosidase inhibitors  Thiazolidinediones  Prandial glucose regulator  ...
Formulation Considerations of Inhaled Products
Formulation Considerations of Inhaled Products

... Good formulation means Sophisticate balance in particle-particle interaction Formulation Considerations of Inhaled Products ...
pdf version here - Health Sciences Authority
pdf version here - Health Sciences Authority

... There is no assurance on the safety, quality and effectiveness of medicines ordered, as they are not evaluated by the authorities. Harmful chemicals or ingredients may be added and such medications can be addictive or harmful to your health. iii. Risk of Poor Quality Products Unapproved medicines ma ...
Uva Ursi - Longwood Herbal Task Force
Uva Ursi - Longwood Herbal Task Force

... absorbed, conjugated to glucuronides and sulfate esters in the liver and excreted renally5, 21, 22. Arbutin is rapidly absorbed after oral administration; renal excretion is also rapid, and 75% is excreted within the first 24 hours5, 23. Arbutin is also found in other herbs and foods, such as sweet ...
A brief review on bioactive compounds in plants
A brief review on bioactive compounds in plants

... The glycosides consist of various categories of secondary metabolites bound to a mono- or oligosaccharide or to uronic acid. The saccharide or uronic acid part is called glycone, and the other part the aglycone. The main groups of glycosides are cardiac glycosides, cyanogenic glycosides, glucosinola ...
Estimating the “First in human” dose – a revisit with particular
Estimating the “First in human” dose – a revisit with particular

... preclinical data. One of the main objectives of the new process is to define a starting dose that is expected to result in a minimum anticipated biological effect level (MABEL), particularly for investigational medicinal products where risk factors were identified in (1) mode of action, (2) nature o ...
In vitro, in vivo and ex vivo models for studying particle deposition
In vitro, in vivo and ex vivo models for studying particle deposition

... The human lung is one of most complex organ systems of the body that are composed of 300–500 million alveoli and a surface area of 100 m2. The main functions of the lungs are to transport oxygen from the environment into the blood and move carbon dioxide back to the atmosphere. In addition to being ...
Options of drugs for intermittent presumptive treatment for malaria in
Options of drugs for intermittent presumptive treatment for malaria in

... anaemia under different levels of transmission can be modelled using a deterministic approach (Appendix 1). The predicted reduction on incidence of severe anaemia achieved with 3 or 2 course regimes of IPTi using a long and short acting antimalarial drug in low and high transmission settings are sho ...
Module 1. General Clinical Pharmacy.Clinical Pharmacy in
Module 1. General Clinical Pharmacy.Clinical Pharmacy in

... C. The cardiovascular condition in which the heart ability to pump blood weakens D. All of the above E. None of the above 36. The drug related to the group of calcium antagonists A. Reserpine B. Apressinum C. * Nifedipine D. Prazosinum E. Papaverini hydrochloridum 37. Which drug decreases the demand ...
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Pharmacognosy



Pharmacognosy is the study of medicinal drugs derived from plants or other natural sources. The American Society of Pharmacognosy defines pharmacognosy as ""the study of the physical, chemical, biochemical and biological properties of drugs, drug substances or potential drugs or drug substances of natural origin as well as the search for new drugs from natural sources.""It is also defined as the study of crude drugs.
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