The Autonomic Nervous System
... reactions through a G protein resulting in the generation of inositol-1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) from phosphatidylinositol. • IP3 initiates the release of Ca2+ from the endoplasmic reticulum into the cytosol, and DAG turns on other proteins within the cell. • The α 1 receptor ...
... reactions through a G protein resulting in the generation of inositol-1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) from phosphatidylinositol. • IP3 initiates the release of Ca2+ from the endoplasmic reticulum into the cytosol, and DAG turns on other proteins within the cell. • The α 1 receptor ...
Relationship between the Serotonergic Activity and Reinforcing
... however, does not seem to predict potential for abuse particularly well. Rather, abuse has been more strongly associated with efficacy or strength as a reinforcer (Brady and Griffiths, 1976). Cocaine, for example, has a relatively weak affinity at the DAT, but it is one of the most efficacious reinf ...
... however, does not seem to predict potential for abuse particularly well. Rather, abuse has been more strongly associated with efficacy or strength as a reinforcer (Brady and Griffiths, 1976). Cocaine, for example, has a relatively weak affinity at the DAT, but it is one of the most efficacious reinf ...
The fight against fake drugs by NAFDAC in Nigeria
... they are cheap, close proximity, no consultation fees, flexible payment method, perception of confidentiality; they feel that the quality of care and attention received are adequate, high stock out rate at the health facilities. Hence, closing such outlets, seizing, destroying and penalizing the vio ...
... they are cheap, close proximity, no consultation fees, flexible payment method, perception of confidentiality; they feel that the quality of care and attention received are adequate, high stock out rate at the health facilities. Hence, closing such outlets, seizing, destroying and penalizing the vio ...
Nomenclature Guideline Outline
... as well as general nomenclature practices. Dosage forms are addressed within USP General Chapter <1151> Pharmaceutical Dosage Forms. The approach taken in <1151> Pharmaceutical Dosage Forms is to classify dosage forms by physical characteristic. For example, solution dosage forms have certain attrib ...
... as well as general nomenclature practices. Dosage forms are addressed within USP General Chapter <1151> Pharmaceutical Dosage Forms. The approach taken in <1151> Pharmaceutical Dosage Forms is to classify dosage forms by physical characteristic. For example, solution dosage forms have certain attrib ...
EVALUATION OF PRELIMINARY PHYTOCHEMICAL PROPERTIES AND HYPOGLYCEMIC CLEOME GYNANDRA Research Article
... was distilled off at low temperature under reduced pressure using rotary flash evaporator. The semisolid mass obtained was dried in an oven at 400C, powdered, labeled as EECG (Ethanolic extract of Cleome gynandra) and stored in desiccator. ...
... was distilled off at low temperature under reduced pressure using rotary flash evaporator. The semisolid mass obtained was dried in an oven at 400C, powdered, labeled as EECG (Ethanolic extract of Cleome gynandra) and stored in desiccator. ...
Horopito - Kolorex
... By the time Captain Cook arrived they had attributed healing properties to many of the plants in their new land. Unlike the Europeans however, they regarded sickness as a spiritual as well as a physical condition. This view is shared by many indigenous peoples worldwide. The ‘psychological’ dimensio ...
... By the time Captain Cook arrived they had attributed healing properties to many of the plants in their new land. Unlike the Europeans however, they regarded sickness as a spiritual as well as a physical condition. This view is shared by many indigenous peoples worldwide. The ‘psychological’ dimensio ...
ASHP Guidelines on Surgery and Anesthesi
... continuation of maintenance medications and discontinuation of unnecessary medications postoperatively. Medication-Use Evaluation. The pharmacist should take a leadership role in the performance of medication-use evaluations by establishing criteria, collecting data, analyzing the data, making recom ...
... continuation of maintenance medications and discontinuation of unnecessary medications postoperatively. Medication-Use Evaluation. The pharmacist should take a leadership role in the performance of medication-use evaluations by establishing criteria, collecting data, analyzing the data, making recom ...
formulation and in vitro evaluation of bilayered buccal patches of a
... enzymes, or due to a substantial hepatic first pass effect. It can also be an alternative to skin, pulmonary, or nasal delivery. The physiology of the buccal mucosa allows for the penetration of active substances and due to its rapid cellular turnover and recovery, the use of penetration enhancers i ...
... enzymes, or due to a substantial hepatic first pass effect. It can also be an alternative to skin, pulmonary, or nasal delivery. The physiology of the buccal mucosa allows for the penetration of active substances and due to its rapid cellular turnover and recovery, the use of penetration enhancers i ...
Drugs
... raves, which are large, all-night dance parties attended by teens and young adults. – GHB, known as liquid Ecstasy, can cause seizures or coma. – “roofies,” is a benzodiazepine that can cause a type of amnesia. It has been used in sexual assaults, and can cause death. Click the mouse button or press ...
... raves, which are large, all-night dance parties attended by teens and young adults. – GHB, known as liquid Ecstasy, can cause seizures or coma. – “roofies,” is a benzodiazepine that can cause a type of amnesia. It has been used in sexual assaults, and can cause death. Click the mouse button or press ...
CMS Annual DUR Report - 2010 - Michigan Department of Health
... The purpose of Michigan’s DUR program is to improve the quality of pharmaceutical care by ensuring that prescriptions are appropriate, medically necessary, and that they are not likely to result in adverse medical results, in accordance with OBRA ’90. DUR assesses data on drug use against predetermi ...
... The purpose of Michigan’s DUR program is to improve the quality of pharmaceutical care by ensuring that prescriptions are appropriate, medically necessary, and that they are not likely to result in adverse medical results, in accordance with OBRA ’90. DUR assesses data on drug use against predetermi ...
This PDF is a selec on from a published volume... Bureau of Economic Research
... an equally important determinant of price levels). Defining regulatory criteria for admitting postpatent generic entrants remains a contentious issue, even for traditional chemical compounds. More complex and yet to be fully resolved by regulatory agencies are the conditions for approving biosimilar ...
... an equally important determinant of price levels). Defining regulatory criteria for admitting postpatent generic entrants remains a contentious issue, even for traditional chemical compounds. More complex and yet to be fully resolved by regulatory agencies are the conditions for approving biosimilar ...
study of formulation, characterisation and wound healing potential of
... dosage forms of a drug substance. It can be defined as an investigation of physical and chemical properties of a drug substance alone and when combined with excipients. The overall objective of pre-formulation study is to generate information useful to the formulator in developing stable and bio ava ...
... dosage forms of a drug substance. It can be defined as an investigation of physical and chemical properties of a drug substance alone and when combined with excipients. The overall objective of pre-formulation study is to generate information useful to the formulator in developing stable and bio ava ...
annexure – ii - Rajiv Gandhi University of Health Sciences
... information center, various standard Books, journals, websites and other sources like research literature bases data such as Medline, Science Direct etc. The experimental data will be collected from study of the drug; its formulation, through investigation of the process and product variables in the ...
... information center, various standard Books, journals, websites and other sources like research literature bases data such as Medline, Science Direct etc. The experimental data will be collected from study of the drug; its formulation, through investigation of the process and product variables in the ...
Opioid analgesics
... in prehistorical times (e.g. in Egypt, Ebers’Papyrus – XVI BC) as an analgesic, tranquillizer, antitussive drug, and for treating diarrhoea. The principal active ingredient in crude opium – morphine, was isolated in 1806 from Frederic Sertűrner, who tested pure drug on himself and three young men. H ...
... in prehistorical times (e.g. in Egypt, Ebers’Papyrus – XVI BC) as an analgesic, tranquillizer, antitussive drug, and for treating diarrhoea. The principal active ingredient in crude opium – morphine, was isolated in 1806 from Frederic Sertűrner, who tested pure drug on himself and three young men. H ...
Information and Innovation Diffusion
... variation in doctors’ treatment decisions reflects, in part, a lack of uniformity in the information they have about available therapies—particularly in disease areas undergoing a rapid expansion in treatment options. Consider for example, changes in the treatment of cardiovascular disease. When the ...
... variation in doctors’ treatment decisions reflects, in part, a lack of uniformity in the information they have about available therapies—particularly in disease areas undergoing a rapid expansion in treatment options. Consider for example, changes in the treatment of cardiovascular disease. When the ...
Chapter 6 - Diabetes and Endocrinology
... 1. The UKPDS showed a significant reduction in diabetes complications in type 2 diabetic patients through tight blood pressure control (regardless of the drug used).The lowering of blood pressure is a very high priority which may require polypharmacy. It is appropriate to aim for HbA1c within normal ...
... 1. The UKPDS showed a significant reduction in diabetes complications in type 2 diabetic patients through tight blood pressure control (regardless of the drug used).The lowering of blood pressure is a very high priority which may require polypharmacy. It is appropriate to aim for HbA1c within normal ...
Toxicokinetics of Emerging Drugs of Abuse: In vivo and in vitro
... die Esterhydrolyse, die Deethylierung, die Hydroxylierung, die N-Acetylierung sowie Kombinationen von diesen identifiziert werden. Für die N- Acetylierung von DMC stellte sich die NAT2 als wichtigstes Enzym dar. ...
... die Esterhydrolyse, die Deethylierung, die Hydroxylierung, die N-Acetylierung sowie Kombinationen von diesen identifiziert werden. Für die N- Acetylierung von DMC stellte sich die NAT2 als wichtigstes Enzym dar. ...
Antihomotoxic Mesotherapy in Sports Injuries of Soft Tissues.
... some cases with a diagnosis made using imaging techniques. The lesions were divided according to the time of evolution into two categories: chronic and acute. An acute lesion was considered of less than four weeks evolution and a chronic one of more than four weeks evolution. The number of lesions e ...
... some cases with a diagnosis made using imaging techniques. The lesions were divided according to the time of evolution into two categories: chronic and acute. An acute lesion was considered of less than four weeks evolution and a chronic one of more than four weeks evolution. The number of lesions e ...
fast dissolving films - Asian Journal of Pharmaceutical Science and
... In the recent years, many of the pharmaceutical groups are focusing their research on rapid dissolving technology. This technology evolved over the past few years from the confection and oral care markets in the form of breath strips and became a novel and widely accepted form by consumers, so OFDFs ...
... In the recent years, many of the pharmaceutical groups are focusing their research on rapid dissolving technology. This technology evolved over the past few years from the confection and oral care markets in the form of breath strips and became a novel and widely accepted form by consumers, so OFDFs ...
P13_JHung_CombProducts
... 1) Assert that the combination drug is more effective than each component drug alone 2) Obtain useful and reliable DR information - identify a dose range where effect increases as a function of dose - identify a dose beyond which there is no appreciable increase of the effect or undesirable effects ...
... 1) Assert that the combination drug is more effective than each component drug alone 2) Obtain useful and reliable DR information - identify a dose range where effect increases as a function of dose - identify a dose beyond which there is no appreciable increase of the effect or undesirable effects ...
Starlix - Novartis Pharmaceuticals Corporation
... changes in level of physical activity, changes to coadministered medication [see Drug Interactions (7)], and concomitant use with other antidiabetic agents. Patients with renal or hepatic impairment may be at higher risk of hypoglycemia [see Use in Specific Populations (8.6, 8.7)]. Patients should t ...
... changes in level of physical activity, changes to coadministered medication [see Drug Interactions (7)], and concomitant use with other antidiabetic agents. Patients with renal or hepatic impairment may be at higher risk of hypoglycemia [see Use in Specific Populations (8.6, 8.7)]. Patients should t ...
Are placebos inert or powerful? Vice versa
... genome’ [9]) is increasingly understood to have far-reaching implications to nutrient assimilation, biotoxin production and health. Some nonabsorbed substances are even given for the purpose of altering gut flora and thereby symptoms, such as nonabsorbed antifungal nystatin powder. ■■ Placebo conten ...
... genome’ [9]) is increasingly understood to have far-reaching implications to nutrient assimilation, biotoxin production and health. Some nonabsorbed substances are even given for the purpose of altering gut flora and thereby symptoms, such as nonabsorbed antifungal nystatin powder. ■■ Placebo conten ...
product monograph trusopt
... vision, itching and tearing. Bitter taste was also frequently reported. If these local symptoms were considered clinically important by investigators they also appear as adverse experiences in the listing below. In an active treatment, controlled, crossover clinical study of 12 weeks duration, 152 p ...
... vision, itching and tearing. Bitter taste was also frequently reported. If these local symptoms were considered clinically important by investigators they also appear as adverse experiences in the listing below. In an active treatment, controlled, crossover clinical study of 12 weeks duration, 152 p ...
Therapeutic Review: Leuprolide Acetate
... However, surgery may not be possible in cases where the animal is not stable (eg, pancytopenia). Surgery also may not be an option in cases where the adrenal gland has metastasized into the vena cava or other visceral organs. In these cases, medical management is preferred. Wagner and coworkers9 eva ...
... However, surgery may not be possible in cases where the animal is not stable (eg, pancytopenia). Surgery also may not be an option in cases where the adrenal gland has metastasized into the vena cava or other visceral organs. In these cases, medical management is preferred. Wagner and coworkers9 eva ...
Pharmacognosy
Pharmacognosy is the study of medicinal drugs derived from plants or other natural sources. The American Society of Pharmacognosy defines pharmacognosy as ""the study of the physical, chemical, biochemical and biological properties of drugs, drug substances or potential drugs or drug substances of natural origin as well as the search for new drugs from natural sources.""It is also defined as the study of crude drugs.