Project submission form for human involvement study
... than an individual that uses one or more of its own employees to conduct an investigation that it has initiated is a sponsor, not a sponsor-investigator, and the employees are investigators. Sponsor-Investigator means an individual who both initiates and conducts an investigation, and under whose im ...
... than an individual that uses one or more of its own employees to conduct an investigation that it has initiated is a sponsor, not a sponsor-investigator, and the employees are investigators. Sponsor-Investigator means an individual who both initiates and conducts an investigation, and under whose im ...
Sections 11 to 17
... incidence of fatal and non-fatal myocardial infarction, stroke and mortality (all causes), as well as the need for coronary by-pass surgery . All remain very costly but may be cost effective for secondary prevention of cardiovascular disease as well as for primary prevention in some very high-risk p ...
... incidence of fatal and non-fatal myocardial infarction, stroke and mortality (all causes), as well as the need for coronary by-pass surgery . All remain very costly but may be cost effective for secondary prevention of cardiovascular disease as well as for primary prevention in some very high-risk p ...
Studies of a benzoporphyrin derivative with Pluronics and D. Dolphin
... a simultaneous increase in the aggregate band with respect to time was observed. At neutral or higher pH, aggregation was diminished (but not completely avoided), probably resulting from the negative–negative charge repulsion of the carboxylate group on 2. The ratio between the aggregate and monomer ...
... a simultaneous increase in the aggregate band with respect to time was observed. At neutral or higher pH, aggregation was diminished (but not completely avoided), probably resulting from the negative–negative charge repulsion of the carboxylate group on 2. The ratio between the aggregate and monomer ...
Thin-layer agar for detection of resistance to rifampicin, ofloxacin
... isolates of M. tuberculosis for the detection of resistance to RMP, KM and OFX, three key anti-tuberculosis drugs in the treatment of TB and MDR-TB. The development of new methods for TB diagnosis that are able to provide earlier results than the conventional methods is a priority for TB control. Wi ...
... isolates of M. tuberculosis for the detection of resistance to RMP, KM and OFX, three key anti-tuberculosis drugs in the treatment of TB and MDR-TB. The development of new methods for TB diagnosis that are able to provide earlier results than the conventional methods is a priority for TB control. Wi ...
Chapter14
... medication and inventory control systems, and participating in the administration and management of pharmacy practice. ...
... medication and inventory control systems, and participating in the administration and management of pharmacy practice. ...
Notes - Georgia Chiropractic Association
... Gelsemium sempervirens: Centers action upon muscles and nerves; Spasms; Paralysis. Hypericum perforatum: Injury to nerves; Effects of surgery; Spasms after every injury; Neuralgia. Ignatia amara: Epilepsy; Locomotor ataxia (loss of muscle control); Numbness; Tremors. Lachesis mutus: Left-sided paral ...
... Gelsemium sempervirens: Centers action upon muscles and nerves; Spasms; Paralysis. Hypericum perforatum: Injury to nerves; Effects of surgery; Spasms after every injury; Neuralgia. Ignatia amara: Epilepsy; Locomotor ataxia (loss of muscle control); Numbness; Tremors. Lachesis mutus: Left-sided paral ...
evaluation of the interaction of loratadine and desloratadine with p
... safety record. This result supports some structure-activity relationship studies showing that less lipophilic (hydrophobic) compounds are often less likely to interact with the substrate binding site of P-gp (Klopman et al., 1997; Litman et al., 1997). As DL is the descarboethoxy oxidized L, it is l ...
... safety record. This result supports some structure-activity relationship studies showing that less lipophilic (hydrophobic) compounds are often less likely to interact with the substrate binding site of P-gp (Klopman et al., 1997; Litman et al., 1997). As DL is the descarboethoxy oxidized L, it is l ...
Suppression of Noxious Stimulus-Evoked Activity in the Ventral
... level (Mitchell and Hellon, 1977; Guilbaud et al., 1980; Peschanski et al., 1980a,b, 1983) (for review, see Willis, 1984). Originating primarily in the dorsal horn of the spinal cord, spinothalamic tract neurons terminate in several thalamic nuclei including the ventroposterolateral (VPL) nucleus (L ...
... level (Mitchell and Hellon, 1977; Guilbaud et al., 1980; Peschanski et al., 1980a,b, 1983) (for review, see Willis, 1984). Originating primarily in the dorsal horn of the spinal cord, spinothalamic tract neurons terminate in several thalamic nuclei including the ventroposterolateral (VPL) nucleus (L ...
Body mass index predicts discontinuation due to ineffectiveness and
... Categorical variables were compared using the v2-test. Significantly different characteristics between ADA, ETA and USTE were corrected for with multivariate Cox regression analysis for drug survival (MCR-DS) in order to adjust for their possible confounding effect when comparing drug survival betwe ...
... Categorical variables were compared using the v2-test. Significantly different characteristics between ADA, ETA and USTE were corrected for with multivariate Cox regression analysis for drug survival (MCR-DS) in order to adjust for their possible confounding effect when comparing drug survival betwe ...
Slide 1
... Plant-like organisms that lack chlorophyll 1 of the 5 Kingdoms More than 100,000 species 400 known to cause disease in plants, animals, and humans Cell: ...
... Plant-like organisms that lack chlorophyll 1 of the 5 Kingdoms More than 100,000 species 400 known to cause disease in plants, animals, and humans Cell: ...
Tardive dystonia - The Dystonia Society
... Since the 1950’s certain strong drugs have been widely used for serious mental health conditions such as schizophrenia or psychosis where they have been found in many cases to have a positive effect. These drugs may also be used for the treatment of some movement disorders such as severe chorea and ...
... Since the 1950’s certain strong drugs have been widely used for serious mental health conditions such as schizophrenia or psychosis where they have been found in many cases to have a positive effect. These drugs may also be used for the treatment of some movement disorders such as severe chorea and ...
Injectable Soft-Tissue Fillers: Clinical Overview
... materials of differing compositions for injection treatments either are now available or will soon be available for clinical use. Methods: A review of the medical literature was performed to provide chemical compositions, methods of preparation, biological behavior, and clinical outcomes for every k ...
... materials of differing compositions for injection treatments either are now available or will soon be available for clinical use. Methods: A review of the medical literature was performed to provide chemical compositions, methods of preparation, biological behavior, and clinical outcomes for every k ...
Information on benefit-risk of medicines: patients`, consumers` and
... by assessing the results of scientific tests and studies that pharmaceutical companies are legally required to perform according to internationally agreed scientific standards, to show the efficacy and safety of a medicine for obtaining a marketing authorisation. The many facets of benefit-risk The ...
... by assessing the results of scientific tests and studies that pharmaceutical companies are legally required to perform according to internationally agreed scientific standards, to show the efficacy and safety of a medicine for obtaining a marketing authorisation. The many facets of benefit-risk The ...
Pharmacokinetic and pharmacodynamic profile of oral and
... ascertain that observed variability is due to the state of the challenged system and not caused by variability of the test itself. This is even more important now that challenge tests increasingly are used in complex studies (e.g. in combination with neuroimaging and in large population studies with ...
... ascertain that observed variability is due to the state of the challenged system and not caused by variability of the test itself. This is even more important now that challenge tests increasingly are used in complex studies (e.g. in combination with neuroimaging and in large population studies with ...
Female sex has been shown to be a risk factor for clinically relevant
... gender, and obesity on midazolam kinetics. Anesthesiology 1984;61:27-35 19. Ochs HR, Greenblatt DJ, Divoll M, Abernethy DR, Feyerabend H, Dengler HJ. Diazepam kinetics in relation to age and sex. Pharmacology 1981;23:24-30. 20. Lane HY, Chang YC, Chang WH, Lin SK, Tseng YT, Jann MW. Effeets of gende ...
... gender, and obesity on midazolam kinetics. Anesthesiology 1984;61:27-35 19. Ochs HR, Greenblatt DJ, Divoll M, Abernethy DR, Feyerabend H, Dengler HJ. Diazepam kinetics in relation to age and sex. Pharmacology 1981;23:24-30. 20. Lane HY, Chang YC, Chang WH, Lin SK, Tseng YT, Jann MW. Effeets of gende ...
BioInvent Financial Statement
... upcoming decade, especially in the field of oncology. BI-505 is one example of BioInvent's capability to initiate in-house clinical projects, based on our own F.I.R.S.T™ technology and biological expertise. It is therefore particularly satisfying to be able to conclude that our first human study of ...
... upcoming decade, especially in the field of oncology. BI-505 is one example of BioInvent's capability to initiate in-house clinical projects, based on our own F.I.R.S.T™ technology and biological expertise. It is therefore particularly satisfying to be able to conclude that our first human study of ...
ABC multidrug transporters: structure, function and role in
... (e.g., ABCB11 transports bile salts; and loss-offunction mutations produce progressive familial intrahepatic cholestasis type 2 [PFIC-2]), whereas for some proteins it remains to be determined (e.g., the disease Pseudoxanthoma elasticum is caused by loss-of-function mutations in ABCC6, whose physiol ...
... (e.g., ABCB11 transports bile salts; and loss-offunction mutations produce progressive familial intrahepatic cholestasis type 2 [PFIC-2]), whereas for some proteins it remains to be determined (e.g., the disease Pseudoxanthoma elasticum is caused by loss-of-function mutations in ABCC6, whose physiol ...
Enalapril Maleate
... were aimed to be taken into account in the PEC evaluation. However, very limited ecotoxicity data are available for enalapril or enalaprilat. Therefore, the Predicted Environmental Concentration (PEC) / Predicted No Effect Concentration (PNEC) has not been determined. No information is available con ...
... were aimed to be taken into account in the PEC evaluation. However, very limited ecotoxicity data are available for enalapril or enalaprilat. Therefore, the Predicted Environmental Concentration (PEC) / Predicted No Effect Concentration (PNEC) has not been determined. No information is available con ...
Anticonvulsants
... CNS depression is probably the most common side effect of anticonvulsants. CNS depressant effects include dizziness, sedation, impaired learning and cognitive abilities, and excitability. Gastrointestinal adverse effects include anorexia, nausea, vomiting, and GI upset. Dermatologic adverse effects ...
... CNS depression is probably the most common side effect of anticonvulsants. CNS depressant effects include dizziness, sedation, impaired learning and cognitive abilities, and excitability. Gastrointestinal adverse effects include anorexia, nausea, vomiting, and GI upset. Dermatologic adverse effects ...
Alcohol and Other Drugs Alcohol and Other Drugs
... This Presenter’s Guide is designed to accompany the PowerPoint presentation “Alcohol and Other Drugs Workshop for National Open Swimmers.” It has been produced to assist coaches, managers and others to facilitate training sessions to swimmers and stakeholders about alcohol and other drugs within the ...
... This Presenter’s Guide is designed to accompany the PowerPoint presentation “Alcohol and Other Drugs Workshop for National Open Swimmers.” It has been produced to assist coaches, managers and others to facilitate training sessions to swimmers and stakeholders about alcohol and other drugs within the ...
Pharmacology and the Nursing Process, 4th ed. Lilley/Harrington
... Last daily dose should be given 4 to 6 hours before bedtime to reduce insomnia Take on an empty stomach, 30 to 45 minutes before meals Drug “holidays” may be ordered Instruct parents to keep a journal to monitor child’s response to therapy Monitor child for continued physical growth, including heigh ...
... Last daily dose should be given 4 to 6 hours before bedtime to reduce insomnia Take on an empty stomach, 30 to 45 minutes before meals Drug “holidays” may be ordered Instruct parents to keep a journal to monitor child’s response to therapy Monitor child for continued physical growth, including heigh ...
COMMITTEE FOR MEDICINAL PRODUCTS FOR HUMAN USE (CHMP) PAEDIATRIC POPULATION
... Many pre-school children attend nurseries or childcare facilities in which they are looked after by caregivers who are not their parents. School-age children are usually under the care of a teacher or teaching assistant but a nurse may be attached to the school. Longer-acting preparations may obviat ...
... Many pre-school children attend nurseries or childcare facilities in which they are looked after by caregivers who are not their parents. School-age children are usually under the care of a teacher or teaching assistant but a nurse may be attached to the school. Longer-acting preparations may obviat ...
PUBLIC ASSESSMENT REPORT of the Medicines Evaluation Board
... Cefixoral (Italy). For the application in the Netherlands and Bulgaria the European Reference Product is Suprax as authorised in Germany. For the 100 mg/5ml powder for oral solution innovator products are available in Italy and Germany. For the application in the Netherlands the historical reference ...
... Cefixoral (Italy). For the application in the Netherlands and Bulgaria the European Reference Product is Suprax as authorised in Germany. For the 100 mg/5ml powder for oral solution innovator products are available in Italy and Germany. For the application in the Netherlands the historical reference ...
Pharmacy Technician Training Systems
... The CNS is composed of the brain and spinal cord Example: Burn your finger, goes to spinal cord to brain, brain says "move finger" Involved in integrating and deciphering all incoming messages and sending responses to the organs and tissues of the body Co-ordinates muscle movements, visualization, t ...
... The CNS is composed of the brain and spinal cord Example: Burn your finger, goes to spinal cord to brain, brain says "move finger" Involved in integrating and deciphering all incoming messages and sending responses to the organs and tissues of the body Co-ordinates muscle movements, visualization, t ...
ESTIMATION OF THE ANTI-ULCER PROPERTIES OF KETOTIFEN IN ASPIRIN AND... STRESS INDUCED ALBINO RATS
... cromoglycate combinations on gastric acidity & gastric ulcers in rabbits & rats. Indian J Pharmacol.1984; 16(3):136-138. 21. Ogle C, Hor KL. Disodium cromoglycate: a novel gastric antiulcer agent? Eur J Pharmacol. 1979; 55:411-415. 22. Nicol AK, Thomas M, Wilson J. Inhibition of gastric acid secreti ...
... cromoglycate combinations on gastric acidity & gastric ulcers in rabbits & rats. Indian J Pharmacol.1984; 16(3):136-138. 21. Ogle C, Hor KL. Disodium cromoglycate: a novel gastric antiulcer agent? Eur J Pharmacol. 1979; 55:411-415. 22. Nicol AK, Thomas M, Wilson J. Inhibition of gastric acid secreti ...
Pharmacognosy
Pharmacognosy is the study of medicinal drugs derived from plants or other natural sources. The American Society of Pharmacognosy defines pharmacognosy as ""the study of the physical, chemical, biochemical and biological properties of drugs, drug substances or potential drugs or drug substances of natural origin as well as the search for new drugs from natural sources.""It is also defined as the study of crude drugs.