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9.3 – Blueprint of Life - Resource Centre / FrontPage
9.3 – Blueprint of Life - Resource Centre / FrontPage

... accompanied by selection, allow change over many generations:  Outline the impact on the evolution of plants and animals of:  Changes in the physical conditions in the environment:  Changes in the chemical condition in the environment:  Competition for resources: – Evolutionary theory states tha ...
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Ku Binds Telomeric DNA in Vitro - Titia de Lange Lab

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Biochemistry 304 2014 Student Edition TRANSCRIPTION

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Replisome



The replisome is a complex molecular machine that carries out replication of DNA. The replisome first unwinds double stranded DNA into two single strands. For each of the resulting single strands, a new complementary sequence of DNA is synthesized. The net result is formation of two new double stranded DNA sequences that are exact copies of the original double stranded DNA sequence.In terms of structure, the replisome is composed of two replicative polymerase complexes, one of which synthesizes the leading strand, while the other synthesizes the lagging strand. The replisome is composed of a number of proteins including helicase, RFC, PCNA, gyrase/topoisomerase, SSB/RPA, primase, DNA polymerase I, RNAse H, and ligase.
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