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Pentadentate thioether-oxime macrocyclic and quasi-macrocyclic complexes of copper(II) and nickel(II)
Pentadentate thioether-oxime macrocyclic and quasi-macrocyclic complexes of copper(II) and nickel(II)

... 77 K cryogenic glass spectra. Macrocyclization by BF2+ enforces the in-plane geometry around the metal ion. © 2000 Elsevier Science S.A. All rights reserved. Keywords: Macrocycle; Crystal structures; Oxime; Copper complexes; Nickel complexes; Electrochemistry; Polarography ...
9. Shikimates and Phenyl propanoids
9. Shikimates and Phenyl propanoids

... aromatic natural products. The isolation of shikimic acid was first reported from aniseed (Illicium anisatum) and the fruit of I. religiosum, whose Japanese name was “shikimi-no-ki” (shi  four; kimi  seasons; no  of; ki  tree, literally “tree of four seasons”). Shikimic acid has since been found ...
Electrone transport chain and oxidative phosphorylation
Electrone transport chain and oxidative phosphorylation

Sensitivity of plant mitochondrial terminal oxidases to the lipid
Sensitivity of plant mitochondrial terminal oxidases to the lipid

... chamber. Total respiration was measured following the addition of 4 mM CCCP (carbonyl cyanide m-chlorophenylhydrazone). Respiration through the alternative pathway or the cytochrome pathway was measured following the addition of 1 mM KCN or 1 mM n-PG respectively. Levels of lipid peroxidation in cel ...
Chemistry 11 Final Examination Review
Chemistry 11 Final Examination Review

... 11. The third energy level of an atom may have __ electrons. a) 2 b) 18 c) 8 d) 32 12. How many sublevels are possible at the fourth energy level? a) 2 b) 3 c) 4 d) 18 13. Lustrous, malleable, ductile elements that are good conductors of electricity and heat are classified as __. a) metals b) nonmet ...
Print - Circulation Research
Print - Circulation Research

... Interactions of the malate-aspartate cycle, the glycolytic pathway, and the citric acid cycle which allow indirect oxidation of cytosolic NADH, rapid alteration of citric acid cycle intermediate levels, and fine coordination of cytosolic and mitochondrial energy metabolism. The malate-a-ketoglutarat ...
A Metabolic Node in Action: Chorismate
A Metabolic Node in Action: Chorismate

... and is retro-inhibited by Tyr (45% for the CM and 95% for the dehydrogenase activity).44,45 It is now evident that the mutase and the dehydrogenase active sites are distinct, but display some similar chemical properties.46-50 Kinetic studies have shown that Tyr binds twice at distinct allosteric sit ...
Fritz Lipmann - National Academy of Sciences
Fritz Lipmann - National Academy of Sciences

... of Lactobacillus delbrueckii. Preparations from this organism were found to contain two cofactors: thiamine pyrophosphate and flavin adenine dinucleotide. A more important observation was that the reaction proceeded only in the presence of inorganic phosphate. Unlike the glycolytic enzymes of yeast, ...
Full-Text PDF
Full-Text PDF

... and TA plays an important role in consumer acceptance of several species, such as citrus [6], table grapes [7] and cherries [8]. In fruit species such as apples, grapes and tomatoes, acidity has long been considered one of the most important quality attributes [9,10]. Several organic acids contribut ...
Lecture 3 Isoelectric Focusing
Lecture 3 Isoelectric Focusing

... It will become -ve (pH>pI and migrate to the anode (+electrode attracts -ion)) As it passes through the gel, eg when it reaches pH 9 region, it becomes less -vely charged (pH not so much >pI) (+electrode does not attract protein so much – protein slows down) When reaches the pH 8 region, protein cha ...
The structure of the two amino-terminal domains of human ICAM
The structure of the two amino-terminal domains of human ICAM

... to the insertion (I)-domain on the a chain of LFA-1 and the carboxyl group of a conserved glutamic acid residue on ICAMs. Domain D1 has been docked with the known structure of the I-domain. The resultant model is consistent with mutational data and provides a structural framework for the adhesion be ...
Iron mediated methylthiolation of tRNA as a regulator of operon
Iron mediated methylthiolation of tRNA as a regulator of operon

... When the S30 extracts from broth-grown E. coli MRE 600 was programmed with MS2 RNA , 36 pp moles valine were incorporated per 150 pi reaction mixture after 30 min. The S30 extract from the bacteria grown in broth containing ovotransferrin, however, incorporated nearly twice this amount, 70 pp moles ...
The Mechanism of Propionic Acid Formation by
The Mechanism of Propionic Acid Formation by

... inhibition studies, that lactate was not on the normal pathway from pyruvate to propionate. The quantitative studies of Werkman & Wood (1942), in which they found equal concentrations of C13 in the carboxyl groups of the succinic and propionic acids, find their simplest interpretation in the presenc ...
liver bile salts - Stanford Medicine
liver bile salts - Stanford Medicine

... Bile Salt Function Lipid digestion and absorption  Essential for the absorption of cholesterol and the fat soluble vitamins; A, D, E, and K.  Major route for cholesterol degradation  Influences cholesterol synthesis and ...
DNA Three Way Junction Core Decorated with Amino Acids
DNA Three Way Junction Core Decorated with Amino Acids

... under mild conditions. Most of the efforts towards DNA-based artificial protease have been conducted by in vitro selection (SELEX methodology) but to date no unmodified nucleic acid sequences have been successfully selected for that purpose [3]. However, a very recent example from the Silverman’s gr ...
Sulfur K-Edge XAS and DFT Calculations on P450 Model
Sulfur K-Edge XAS and DFT Calculations on P450 Model

... electronic structure and reactivity of metal-sulfur sites in proteins. To develop a quantitative understanding of this effect, S K-edge X-ray absorption spectroscopy (XAS) has been employed to directly probe ligandmetal bond covalency, where it has been found that protein active sites are significan ...
IIT-JEE (Advanced) - Brilliant Public School Sitamarhi
IIT-JEE (Advanced) - Brilliant Public School Sitamarhi

... [Useful when only two reactant are there] By calculating amount of any one product obtained taking each reactant one by one irrespective of other reactants. The one giving least product is limiting reagent. Divide given moles of each reactant by their stoichiometric coefficient, the one with least r ...
Carbon isotope analysis of bulk keratin and single amino acids from
Carbon isotope analysis of bulk keratin and single amino acids from

... Previous work on the isotopic composition of human hair keratin addressed differences between individuals from different geographical locations,23,24 and on different diets within the same population.10,25,26 A number of animalfeeding studies have also been conducted.15–17 O’Connell and Hedges found ...
Hexose Monophosphate Shunt (HMP Shunt)
Hexose Monophosphate Shunt (HMP Shunt)

... HMP shunt (PPP) is less active in skeletal muscle & non-lactating mammary glands Site:- ...
Dr: Mohamed I Kotb El
Dr: Mohamed I Kotb El

...  Creatine is synthesized primarily in the liver from arginine, glycine, and methionine.  It is then transported to other tissues, such as muscle, where it is converted to creatine phosphate, which serves as a high-energy source.  About 1-2% of the total muscle creatine pool is converted daily to ...
Phar 722 Pharmacy Practice III
Phar 722 Pharmacy Practice III

... Keto or ureido form ...
A Metal-Based Inhibitor of Tumor Necrosis Factor-α
A Metal-Based Inhibitor of Tumor Necrosis Factor-α

... biologically active trimer complex. This suggests that the inhibition of TNF-α activity by 1 involves shape complementarity between the metal complex and the protein binding pocket, and is not due to an unspecific hydrophobic effect. Substitution of biq for aqua ligands (4a) also significantly reduc ...
Early bioenergetic evolution
Early bioenergetic evolution

... A number of submarine hydrothermal vents have been studied. They differ in the specific temperature and the chemical compositions of their effluent fluid [10,16]. Most are located at the seafloor spreading zone, that is, directly above magma chambers. As such, their effluent comes directly into cont ...
Proceeding of the National Academy of Sciences of the USA 2006
Proceeding of the National Academy of Sciences of the USA 2006

... the first and most studied being one whose core contains seven irons and one molybdenum (1–4). ‘‘Alternative’’ nitrogenases are now known, one that contains vanadium instead of molybdenum (which functions when Mo is absent and V is available) and another that contains only iron (which functions when ...
video slide
video slide

... that occurs without oxygen • Cellular respiration consumes oxygen and organic molecules and yields ATP • Cellular Respiration Equation: ...
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Metalloprotein



Metalloprotein is a generic term for a protein that contains a metal ion cofactor. A large number of all proteins are part of this category.
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