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Burdette, S.C., Walkup, G.K., Spingler, B., Tsien, R.Y. and Lippard, S.J.
... zinc in living cells. These alternative sensors are not suitable for intracellular work because of either unsatisfactory binding affinity, optical properties, and cell toxicity, or the need to perform microinjections into cells. Several traditional Ca2+ and Mg2+ probes have been utilized to study Zn ...
... zinc in living cells. These alternative sensors are not suitable for intracellular work because of either unsatisfactory binding affinity, optical properties, and cell toxicity, or the need to perform microinjections into cells. Several traditional Ca2+ and Mg2+ probes have been utilized to study Zn ...
Metabolic significance of inorganic triphosphate, thiamine
... responsible for this activity. We showed that the E. coli CYTH enzyme, ygiF, although highly specific for PPPi plays only a minor role in the cytosolic PPPase activity, while most of the activity is due to inorganic pyrophosphatase. In animal tissues, most PPPase activity is due to the short-chain e ...
... responsible for this activity. We showed that the E. coli CYTH enzyme, ygiF, although highly specific for PPPi plays only a minor role in the cytosolic PPPase activity, while most of the activity is due to inorganic pyrophosphatase. In animal tissues, most PPPase activity is due to the short-chain e ...
On the Nucleotide Sequence of Yeast Tyrosine Transfer RNA
... construct very similar base-paired structures in spite of the limited similarities in sequences. This model was first suggested by J. R. Penswick and was further refined by E. B. Keller. Only 11 out of the 31 nucleotides shown in Table 3 as being in the same location in both RNAs are located in the ...
... construct very similar base-paired structures in spite of the limited similarities in sequences. This model was first suggested by J. R. Penswick and was further refined by E. B. Keller. Only 11 out of the 31 nucleotides shown in Table 3 as being in the same location in both RNAs are located in the ...
FLAVIN MONONUCLEOTIDE PHOSPHATASE FROM GOAT LIVER: A POSSIBLE TARGET FOR
... essential coenzyme form of the vitamin riboflavin, and occurs widespread in plant and animal organisms [1, 34]. FMN and FAD are formed from riboflavin in liver, intestinal mucosa and other tissues. A great number of mammalian enzymes require FMN or Flavin adenine dinucleotide (FAD) as coenzymes for ...
... essential coenzyme form of the vitamin riboflavin, and occurs widespread in plant and animal organisms [1, 34]. FMN and FAD are formed from riboflavin in liver, intestinal mucosa and other tissues. A great number of mammalian enzymes require FMN or Flavin adenine dinucleotide (FAD) as coenzymes for ...
Oxidation of C`4-labeled Carbohydrate
... high respiration, and a respiratory quotient which is intermediate between 0.7 and 1.0 are some of the biochemical properties which are noted quite constantly in a high proportion of ma lignant tumors (6). In his classical studies of tumor metabolism Warburg (53) placed great emphasis upon the relat ...
... high respiration, and a respiratory quotient which is intermediate between 0.7 and 1.0 are some of the biochemical properties which are noted quite constantly in a high proportion of ma lignant tumors (6). In his classical studies of tumor metabolism Warburg (53) placed great emphasis upon the relat ...
University of Groningen Transport processes in penicillin
... transmembrane fluxes are tightly controlled and potentially determine the overall rate or levels of intermediates in various metabolic pathways [160]. Clearly, strain improvement through metabolic engineering demands solid information on transport. This thesis describes studies on the nature of plas ...
... transmembrane fluxes are tightly controlled and potentially determine the overall rate or levels of intermediates in various metabolic pathways [160]. Clearly, strain improvement through metabolic engineering demands solid information on transport. This thesis describes studies on the nature of plas ...
DISCOVERY OF ENZYMES RESPONSIBLE FOR AN ALTERNATE
... (2). Archaea are now positioned in a separate domain with bacteria and eukaryotes representing the other domains and creating the three domain biological classification system most prominent today. Their unique nature and independent evolutionary history prompts vigorous debate about not only the ev ...
... (2). Archaea are now positioned in a separate domain with bacteria and eukaryotes representing the other domains and creating the three domain biological classification system most prominent today. Their unique nature and independent evolutionary history prompts vigorous debate about not only the ev ...
Weak Intermolecular Interactions in the Solid State
... halogen bonding is a strong, specific, and directional interaction13b that can in quite many cases overrule other intermolecular interactions, such as hydrogen bonding, π···π, cation···π and C–H···π interactions. The nature of the halogen bond, determined as the interaction of a polarized halogen at ...
... halogen bonding is a strong, specific, and directional interaction13b that can in quite many cases overrule other intermolecular interactions, such as hydrogen bonding, π···π, cation···π and C–H···π interactions. The nature of the halogen bond, determined as the interaction of a polarized halogen at ...
Flux analysis in central carbon metabolism in plants
... enumeration of feasible bondomers in a metabolic network reduced the number of bondomer balances 3-fold. This resulted in a simplified system that offers the advantages of faster computation, and easier flux identifiability analysis. Furthermore, a computational technique called Boolean function map ...
... enumeration of feasible bondomers in a metabolic network reduced the number of bondomer balances 3-fold. This resulted in a simplified system that offers the advantages of faster computation, and easier flux identifiability analysis. Furthermore, a computational technique called Boolean function map ...
Full-Text PDF
... that of the HPQ-containing cyclic peptide [27]. On the other hand, mock (Sal-unconjugated) peptide bound to streptavidin with a roughly 10-fold lower affinity under reducing conditions (Figure 7A, right panel). This again suggests that the excellent pharmacophore was generated only when Sal was surr ...
... that of the HPQ-containing cyclic peptide [27]. On the other hand, mock (Sal-unconjugated) peptide bound to streptavidin with a roughly 10-fold lower affinity under reducing conditions (Figure 7A, right panel). This again suggests that the excellent pharmacophore was generated only when Sal was surr ...
bacterial hemoglobin proteins - ETH E-Collection
... substrate oxidation to the reduction of oxygen. ...
... substrate oxidation to the reduction of oxygen. ...
Role of changes in cardiac metabolism in development - AJP
... When compared with glucose, FA is the preferred substrate and accounts for ⬃70% of ATP generated in an aerobic heart. FA metabolism includes multiple steps and can be regulated by both acute and chronic mechanisms, with or without modulation of gene expression (Fig. 2). Lipoprotein lipase. Because t ...
... When compared with glucose, FA is the preferred substrate and accounts for ⬃70% of ATP generated in an aerobic heart. FA metabolism includes multiple steps and can be regulated by both acute and chronic mechanisms, with or without modulation of gene expression (Fig. 2). Lipoprotein lipase. Because t ...
Safety assessment - Federal Register of Legislation
... The assessment of this Application identified no public health and safety concerns. On the basis of the available evidence, including detailed studies provided by the Applicant, food derived from corn line 88017 is considered as safe and wholesome as food derived from other commercial corn varieties ...
... The assessment of this Application identified no public health and safety concerns. On the basis of the available evidence, including detailed studies provided by the Applicant, food derived from corn line 88017 is considered as safe and wholesome as food derived from other commercial corn varieties ...
Ylide Ligands - DIGITAL.CSIC, el repositorio institucional
... principle, a singlet carbene and the nucleophile ZnE. Therefore, it is not surprising that the reaction bewteen a carbene and the corresponding nucleophile (R3P, R3N, R2S, etc) gives cleanly the expected ylide (method d) [2,3,4,9]. The carbene is usually stabilized as a diazo derivative. This method ...
... principle, a singlet carbene and the nucleophile ZnE. Therefore, it is not surprising that the reaction bewteen a carbene and the corresponding nucleophile (R3P, R3N, R2S, etc) gives cleanly the expected ylide (method d) [2,3,4,9]. The carbene is usually stabilized as a diazo derivative. This method ...
Iridium Complex-Catalyzed Highly Selective Organic Synthesis
... An iridium complex was found to be an efficient catalyst for highly branched product-selective allylic alkylation.16 We examined the reaction of (E)-2-hexenyl acetate [(E)2a] with diethyl sodiomalonate (3a) in the presence of a catalytic amount of [Ir(cod)Cl]2 (Ir atom 4 mol%), and found that an add ...
... An iridium complex was found to be an efficient catalyst for highly branched product-selective allylic alkylation.16 We examined the reaction of (E)-2-hexenyl acetate [(E)2a] with diethyl sodiomalonate (3a) in the presence of a catalytic amount of [Ir(cod)Cl]2 (Ir atom 4 mol%), and found that an add ...
universidade estadual de maringá metabolic alterations caused by
... activity as an uncoupler. At higher concentrations, however, several other effects may become significant, including inhibition of mitochondrial electron flow and inhibition of medium-chain fatty acid oxidation. In metabolic ...
... activity as an uncoupler. At higher concentrations, however, several other effects may become significant, including inhibition of mitochondrial electron flow and inhibition of medium-chain fatty acid oxidation. In metabolic ...
Unsaturated and Odd-Chain Fatty Acid Catabolism
... organelles that carry out flavin dependent oxidation reactions that produce highly reactive oxygen species such as hydrogen peroxide. Peroxisomes are abundant in liver and kidney tissues. Each liver cell contains about 1,000 peroxisomes. The peroxisomes contain high concentrations of catalase which ...
... organelles that carry out flavin dependent oxidation reactions that produce highly reactive oxygen species such as hydrogen peroxide. Peroxisomes are abundant in liver and kidney tissues. Each liver cell contains about 1,000 peroxisomes. The peroxisomes contain high concentrations of catalase which ...
Enzymatic function of nitric oxide synthases
... Hence, only the Ca 21 -bound conformation of CaM can activate the enzyme. This dependence on Ca 21 may be ultimately due to the presence of an autoinhibitory sequence which is present in the FMN-binding region of the two Ca 21 -dependent isoforms but is not found in iNOS [61]. The CaM-binding region ...
... Hence, only the Ca 21 -bound conformation of CaM can activate the enzyme. This dependence on Ca 21 may be ultimately due to the presence of an autoinhibitory sequence which is present in the FMN-binding region of the two Ca 21 -dependent isoforms but is not found in iNOS [61]. The CaM-binding region ...
Transition Metal-Modified Zirconium Phosphate Electrocatalysts for
... precious metals [15,16]. Significant research has been conducted to improve electrocatalysts through based on precious metals [15,16]. Significant research has been conducted to improve electrocatalysts a number of general strategies, including increasing the number of active sites, increasing the ...
... precious metals [15,16]. Significant research has been conducted to improve electrocatalysts through based on precious metals [15,16]. Significant research has been conducted to improve electrocatalysts a number of general strategies, including increasing the number of active sites, increasing the ...
questions based on high order thinking skill
... of end face centred (monoclinic) lattice with a molecule at each lattice. Ans. 2. Q. 3. What is the coordination number of carbon, in diamond ? Ans. 4 and its unit cell has 8 atoms. [The space lattice of diamond is FCC] Q. 4. Name the solid which has weakest intermolecular force ? Ans. Ice Q. 5. Arr ...
... of end face centred (monoclinic) lattice with a molecule at each lattice. Ans. 2. Q. 3. What is the coordination number of carbon, in diamond ? Ans. 4 and its unit cell has 8 atoms. [The space lattice of diamond is FCC] Q. 4. Name the solid which has weakest intermolecular force ? Ans. Ice Q. 5. Arr ...
Metalloprotein
![](https://commons.wikimedia.org/wiki/Special:FilePath/1GZX_Haemoglobin.png?width=300)
Metalloprotein is a generic term for a protein that contains a metal ion cofactor. A large number of all proteins are part of this category.