fulltext - DiVA portal
... the explosion of high-throughput data generation over the last decade, these repositories have grown exponentially in size. Currently, GEO contains more than 150,000 mRNA microarray studies alone, as well as several other forms of high-throughput data. Because scientific journals require that high t ...
... the explosion of high-throughput data generation over the last decade, these repositories have grown exponentially in size. Currently, GEO contains more than 150,000 mRNA microarray studies alone, as well as several other forms of high-throughput data. Because scientific journals require that high t ...
ppt - Chair of Computational Biology
... activator. At the end of the circadian cycle, the PER and CRY proteins are degraded in a CKI-dependent manner, which releases the repression of the transcription and allows the next cycle to start. An additional stabilizing feedback loop, which involves the activator Rora and the inhibitor Rev-Erbα, ...
... activator. At the end of the circadian cycle, the PER and CRY proteins are degraded in a CKI-dependent manner, which releases the repression of the transcription and allows the next cycle to start. An additional stabilizing feedback loop, which involves the activator Rora and the inhibitor Rev-Erbα, ...
Genetic Review 2007 - Wayne State University
... Meiosis: Once a diploid cell differentiates to the germ line, there is one duplication in S phase of interphase (46x2=92) & two divisions (92/2=46; 46/2=23), forming a haploid gamete. 3) Describe how meiosis facilitates the three major features of Mendelian genetics: segregation, independent assor ...
... Meiosis: Once a diploid cell differentiates to the germ line, there is one duplication in S phase of interphase (46x2=92) & two divisions (92/2=46; 46/2=23), forming a haploid gamete. 3) Describe how meiosis facilitates the three major features of Mendelian genetics: segregation, independent assor ...
Our laboratory studies the regulation of gene expression in
... We have identified histone acetyl transferases and deacetylases that affect gene expression in a position-dependent, promoter-independent (silencing) manner. More recently, we have identified histone methyltransferases that also affect silencing. We are especially interested to know how these and ot ...
... We have identified histone acetyl transferases and deacetylases that affect gene expression in a position-dependent, promoter-independent (silencing) manner. More recently, we have identified histone methyltransferases that also affect silencing. We are especially interested to know how these and ot ...
Test Information Sheet
... with a broad range of clinical presentations. The steroid abnormalities result in a rare form of congenital adrenal hyperplasia (CAH) that accounts for about 1% of cases of CAH overall. The 17α-hydroxylase deficiency leads to diminished cortisol production, although adrenal insufficiency is rare bec ...
... with a broad range of clinical presentations. The steroid abnormalities result in a rare form of congenital adrenal hyperplasia (CAH) that accounts for about 1% of cases of CAH overall. The 17α-hydroxylase deficiency leads to diminished cortisol production, although adrenal insufficiency is rare bec ...
Lesson Overview
... Base pairing in the double helix explained how DNA could be copied, or replicated, because each base on one strand pairs with only one base on the opposite strand. Each strand of the double helix has all the information needed to reconstruct the other half by the mechanism of base pairing. Because e ...
... Base pairing in the double helix explained how DNA could be copied, or replicated, because each base on one strand pairs with only one base on the opposite strand. Each strand of the double helix has all the information needed to reconstruct the other half by the mechanism of base pairing. Because e ...
PDF
... acting at different times and always in the same sequence. At first, such a model seems to be in contradiction to some observations that suggest that, in some systeffiS, posterior body parts can regenerate anterior portions (e.g.Slack, 1980). However, it is not clear whether, in these particular cas ...
... acting at different times and always in the same sequence. At first, such a model seems to be in contradiction to some observations that suggest that, in some systeffiS, posterior body parts can regenerate anterior portions (e.g.Slack, 1980). However, it is not clear whether, in these particular cas ...
Concepts in Biochemistry 3/e
... and action of pyruvate dehydrogenase (this glucosederived acetyl-CoA used in the synthesis of f.acids) G6P can be degraded via pentose phosphate pathway (to generate NADPH required for f.acids biosynthesis and liver’s many other biosynthetic functions) ...
... and action of pyruvate dehydrogenase (this glucosederived acetyl-CoA used in the synthesis of f.acids) G6P can be degraded via pentose phosphate pathway (to generate NADPH required for f.acids biosynthesis and liver’s many other biosynthetic functions) ...
Pedigree Charts Introduction
... they can also be described as heterozygous-they have 1 of each gene • What is their PHENOTYPE? (Roller or non-roller?) • The youngest son has a genotype of rr-he is Homozygous recessive-2 copies of the recessive gene • His phenotype? ...
... they can also be described as heterozygous-they have 1 of each gene • What is their PHENOTYPE? (Roller or non-roller?) • The youngest son has a genotype of rr-he is Homozygous recessive-2 copies of the recessive gene • His phenotype? ...
Traits and Inheritance
... Others are pairings of one trait that result in blended or combinations of traits that are neither recessive or dominant. ...
... Others are pairings of one trait that result in blended or combinations of traits that are neither recessive or dominant. ...
Patterns of Inheritance Chp 10
... appearance = dominant. The other has no noticeable effect on organism’s appearance = recessive - The phenotype is the appearance or expression of a trait - The genotype is the genetic makeup of a trait - The same phenotype may be determined by more than one genotype ...
... appearance = dominant. The other has no noticeable effect on organism’s appearance = recessive - The phenotype is the appearance or expression of a trait - The genotype is the genetic makeup of a trait - The same phenotype may be determined by more than one genotype ...
Nucleic Acids Research
... gene, and a 238 bp fragment containing the 3' noncoding region of this gene. When the 38 hybridizing recombinant phage were analyzed with the 2 smaller probes, 9 hybridized to the coding region probe and 29 hybridized to the A-T rich 3' noncoding region probe. The coding region isolates were further ...
... gene, and a 238 bp fragment containing the 3' noncoding region of this gene. When the 38 hybridizing recombinant phage were analyzed with the 2 smaller probes, 9 hybridized to the coding region probe and 29 hybridized to the A-T rich 3' noncoding region probe. The coding region isolates were further ...
Allele - CARNES AP BIO
... Will often see the A,B designation as superscripts with a base of I; O (since is recessive to A and B) is shown as i. ...
... Will often see the A,B designation as superscripts with a base of I; O (since is recessive to A and B) is shown as i. ...
/+ +/+ +/+ +/+ a +/ b - Molecular and Cell Biology
... you sift through chromosomes (often one at a time) looking for mutant alleles of interest/use ...
... you sift through chromosomes (often one at a time) looking for mutant alleles of interest/use ...
Awards for August 2010 Cycle The Scientific Advisory Board (SAB
... for FSHD, we have taken advantage of conditional toxicity of DUX4-inducible myoblasts and we developed a small molecule screening platform for identifying inhibitors of DUX4. In our iC2C12-DUX4 inducible myoblasts, we incorporated full length of the last D4Z4 repeat, so prior its induction, we can n ...
... for FSHD, we have taken advantage of conditional toxicity of DUX4-inducible myoblasts and we developed a small molecule screening platform for identifying inhibitors of DUX4. In our iC2C12-DUX4 inducible myoblasts, we incorporated full length of the last D4Z4 repeat, so prior its induction, we can n ...
Gene Section BLM (Bloom) Atlas of Genetics and Cytogenetics in Oncology and Haematology
... premature nonsense codons into the coding sequence have been described to date; one BLM mutation consisting in a 6 bp deletion accompanied by a 7 bp insertion at nucleic acid position 2281 is common in patients from Ashkenazi Jewish ancestry, leading to a truncated protein of 739 amino acids in leng ...
... premature nonsense codons into the coding sequence have been described to date; one BLM mutation consisting in a 6 bp deletion accompanied by a 7 bp insertion at nucleic acid position 2281 is common in patients from Ashkenazi Jewish ancestry, leading to a truncated protein of 739 amino acids in leng ...
LOTUS-DB: an integrative and interactive database for
... crescent attentions from researchers all over the world. The genetic or molecular studies on this species depend on its genome information. In 2013, two publications reported the sequencing of its full genome, based on which we constructed a database named as LOTUS-DB. It will provide comprehensive ...
... crescent attentions from researchers all over the world. The genetic or molecular studies on this species depend on its genome information. In 2013, two publications reported the sequencing of its full genome, based on which we constructed a database named as LOTUS-DB. It will provide comprehensive ...
Anopheles gambiae APL1 Is a Family of Variable LRR Proteins
... levels in APL1A and APL1B silenced mosquitoes were not different from GFP controls. However, treatment with either dsAPL1C or dsAPL1 (targeting all 3 genes) permitted significantly greater oocyst development than the other treatments (asterisk, p,0.05 by Dunn’s Multiple Comparison after Kruskal Wall ...
... levels in APL1A and APL1B silenced mosquitoes were not different from GFP controls. However, treatment with either dsAPL1C or dsAPL1 (targeting all 3 genes) permitted significantly greater oocyst development than the other treatments (asterisk, p,0.05 by Dunn’s Multiple Comparison after Kruskal Wall ...
"Preparation of Genomic DNA from Bacteria". In: Current Protocols in
... complexes both with polysaccharides and with residual protein; both groups of contaminating molecules are effectively removed in the subsequent emulsification and extraction with chloroform/isoamyl alcohol. This procedure is effective in producing digestible chromosomal DNA from a variety of gram-ne ...
... complexes both with polysaccharides and with residual protein; both groups of contaminating molecules are effectively removed in the subsequent emulsification and extraction with chloroform/isoamyl alcohol. This procedure is effective in producing digestible chromosomal DNA from a variety of gram-ne ...
Patterns of Inheretance
... Snap dragons (four o-clocks) flower color varieties: red, white, and pink ...
... Snap dragons (four o-clocks) flower color varieties: red, white, and pink ...
Who was Gregor Mendel?
... Homologous Pairs When making a new organism, one gene from the mother matches up with a “similar” gene from the father These genes are called “homologous” pairs Homologous means similar (in length, size, genetic make up, etc…) ...
... Homologous Pairs When making a new organism, one gene from the mother matches up with a “similar” gene from the father These genes are called “homologous” pairs Homologous means similar (in length, size, genetic make up, etc…) ...
Ciliated dendrite mRNA may control olfactory sensory neuron
... the only few instances of adult neurogenesis in the central nervous system. It has raised high interest in dissecting the pathways for neural development, differentiation and survival. Odorant stimulation protects OSN from dying. OSN survival thus depends on an efficient defense against external agg ...
... the only few instances of adult neurogenesis in the central nervous system. It has raised high interest in dissecting the pathways for neural development, differentiation and survival. Odorant stimulation protects OSN from dying. OSN survival thus depends on an efficient defense against external agg ...
Preparation and analysis of environmental DNA: optimisation of
... recovering symbiotic, stationary or slow growing organisms, and the so called viable but non-cultivable fraction which are believed to make up the bulk of environmental organisms [1]. The development of DNA-based techniques which rely on analysis of DNA extracted from microorganisms inhabiting a par ...
... recovering symbiotic, stationary or slow growing organisms, and the so called viable but non-cultivable fraction which are believed to make up the bulk of environmental organisms [1]. The development of DNA-based techniques which rely on analysis of DNA extracted from microorganisms inhabiting a par ...