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3D dose verification for advanced radiotherapy
3D dose verification for advanced radiotherapy

... dosimetry). This thesis deals with both strategies. First, the pre-treatment verification part deals with verification methods and procedures that are applied before the first fraction of a treatment is given. These pretreatment verification strategies are useful for detecting errors made during tre ...
portal dosimetry in radiotherapy
portal dosimetry in radiotherapy

... photon  beam  treatment  with  linear  accelerators  (LINACs)4‐6.  With  these  devices,  electrons are generated and accelerated to high energies of 4‐25 MeV. The accelerated  electrons  produce  X‐rays  when  they  collide  with  a  tungsten  target  and  the  resulting  photon  beam  can  be  use ...
Biologically conformal radiation therapy and Monte
Biologically conformal radiation therapy and Monte

... changes in physical properties within patients. Additionally, tumor biology plays an important role in the diagnosis, treatment decisionmaking and the assessment of therapeutic response. Recent advances in biological imaging techniques, mainly based on positron emission tomography (PET), offer the o ...
An X-ray Source Model and Characterization Method for Computing
An X-ray Source Model and Characterization Method for Computing

... minimizing the irradiation of healthy tissues. While this conformality increases the radiation treatment plan quality, it also causes higher dose gradients near the edges of the treated area. These plans therefore require more precise patient positioning[135, 35]. Historically, patients were positio ...
A literature review of electronic portal imaging for
A literature review of electronic portal imaging for

... from paper to electronic systems, or from manual to automatic systems. Regardless of whether the treatment technique is conventional or advanced, the department is large or small, or the treatment makes use of the latest technology or not, errors can, and often do, occur during the delivery process. ...
3 Prostate Ragab Hani Donkol and Ahmad Al Nammi
3 Prostate Ragab Hani Donkol and Ahmad Al Nammi

... prostate. The first clinically applicable images of the prostate obtained with TRUS were described in 1967 by Watanabe et al, they used a 3.5 MHz transducer, which at that time was considered to be state of the art, to obtain images that were clinically meaningful. As US technology has become more r ...
Development and testing of extra-cranial tumour tracking
Development and testing of extra-cranial tumour tracking

... respiratory signal is extracted from the external surface displacement and modelled to derive the instantaneous values of amplitude and phase variables. To take into account possible inter-fraction anatomical variations that may occur between planning and treatment time, the tumour baseline in the ...
Imaging dose from cone beam computed tomography in radiation
Imaging dose from cone beam computed tomography in radiation

... There have been over 500 publications since early 2000s that include terms such as “cone beam CT” or “CBCT” and “radiation therapy” or “radiotherapy” as a key word, based on the advanced search performed using the engine Scopus.com (Elsevier B.V., The Netherlands). This review was conducted by searc ...
American Association of Physicists in Medicine 40th Annual
American Association of Physicists in Medicine 40th Annual

... This is a landmark year for the Annual Meeting for two prominent reasons. For the first time, both the positions of Scientific Program Director and Co-Director are filled by women members of the Association. Drs. Mary Martel and Maryellen Giger have worked diligently to develop an outstanding scient ...
CT Dosimetry: Com- parison of Measure- ment
CT Dosimetry: Com- parison of Measure- ment

... CT provides an image of normalized tissue attenuation values. Also, image noise is reduced if radiation is increased; consequently, a CT image looks fine (often better) if excessive radiation is used. Thus, without dose measurements, the CT user lacks the visual cues needed to appropriately adjust t ...
The management of imaging dose during image-guided
The management of imaging dose during image-guided

... quality will be acquired at a total dose that is at least several times that of a single high-quality CT and potentially as much as the cumulative dose from ten individual CTs. If organ motion is going to be accommodated in a planning target volume 共PTV兲 margin then the CT can provide the margin inf ...
The management of imaging dose during image-guided
The management of imaging dose during image-guided

... quality will be acquired at a total dose that is at least several times that of a single high-quality CT and potentially as much as the cumulative dose from ten individual CTs. If organ motion is going to be accommodated in a planning target volume 共PTV兲 margin then the CT can provide the margin inf ...
Characterization of the homogeneous tissue mixture approximation
Characterization of the homogeneous tissue mixture approximation

... the use of dose estimates in absolute terms, such as for risk estimates, and may impact some comparative studies, such as when modalities or techniques with different x-ray energies are used. The error introduced by the homogeneous tissue mixture approximation in higher energy x-ray modalities, such ...
article in press - The EndoExperience
article in press - The EndoExperience

... Ludlow et al. shows a good overall reproducibility (2.5% variation between repeated identical examinations), although some specific TLD locations showed a large variation [11]. It is clear that effective dose estimations are dependent on many factors which are not standardised, such as the phantom i ...
Assessing The Clinical Application Of The Van Herk Margin Formula
Assessing The Clinical Application Of The Van Herk Margin Formula

... 4.3 Investigation of tissue density................................................................................................. 86 4.4 Evaluation of VHMF dose model ........................................................................................... 89 4.4.1 Investigation of the van Herk ...
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The concept and challenges of TomoTherapy accelerators

... points of content expansion for keen readers. Radiotherapy is an essential element in the treatment of cancer patients; it is used alone or in combination with surgery or chemotherapy, and it has become a well-recognized curative and palliative therapy. Because of localization uncertainties, a margi ...
Breast Microcalcifications - Diagnostic Centers of America
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... severity of a patient's clinical condition should dictate the selection of appropriate imaging procedures or treatments. Only those exams generally used for evaluation of the patient's condition are ranked. Other imaging studies necessary to evaluate other co-existent diseases or other medical conse ...
International Workshop on Monte Carlo Techniques in Medical
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... artificial implants from CAD modeling (screws, hip replacements, brachytherapy seeds, etc) or anatomical details extracted from other imaging modalities, such as for example MRI (arteries, spinal cord, atheroma, etc). A potential solution based on the use of smaller voxels for modeling complex objec ...
Computed Tomography Radiation Safety Issues in Ontario
Computed Tomography Radiation Safety Issues in Ontario

... and guidance of interventional and therapeutic procedures. It allows rapid acquisition of high-resolution three-dimensional images, providing radiologists and other physicians with cross-sectional views of the patient’s anatomy. CT can be used to image many types of tissues, such as soft tissues, bo ...
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... Guidance of interventional procedures Evaluation of problems associated with breast implants Treatment planning for radiation therapy ...
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Chapter 15: Special Procedures and Techniques in

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06. Radiation Protection of Children During Computed Tomography
06. Radiation Protection of Children During Computed Tomography

... Without a reduction in tube current (mA) this leads to a significantly higher dose. 100 kVp or 80 kVp is usually adequate for children. Lowering of kVp enhances contrast 10 kg patient transmits 3-4% while an adult transmits less than 0.1%. Be aware that images with high noise, even if they do not lo ...
Process Management and Quality Assurance for Intracranial
Process Management and Quality Assurance for Intracranial

... implement a new treatment technique as well as the treatment technique process itself, to ensure state-of-the-art treatments, i.e. safe treatments with a high quality. The reason is three-fold. First, choices made by the departmental management influence, in a positive or negative way, the quality a ...
Radiation Dose and Safety: Informatics Standards and Tools
Radiation Dose and Safety: Informatics Standards and Tools

... such as those performed in most diagnostic imaging exams to a whole-body exposure of radiation with the same risk. The technical basis of computing effective dose requires that a collection of organ doses be assessed (in absorbed dose units, mGy); then, a series of tissue-weighting factors are used ...
PDF
PDF

... different regions: the exposed breast region and the unexposed air-background (non-breast) region. Breast regions can be partitioned into: 1. Near-skin tissue region, which contains uncompressed fatty tissue, positioned at the 2. periphery of the breast, close to the skin-air interface where the bre ...
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Brachytherapy

Brachytherapy (from the Greek word βραχύς brachys, meaning ""short-distance""), also known as internal radiotherapy, sealed source radiotherapy, curietherapy or endocurietherapy, is a form of radiotherapy where a sealed radiation source is placed inside or next to the area requiring treatment. Brachytherapy is commonly used as an effective treatment for cervical, prostate, breast, and skin cancer and can also be used to treat tumours in many other body sites.Brachytherapy can be used alone or in combination with other therapies such as surgery, external beam radiotherapy (EBRT) and chemotherapy.Brachytherapy contrasts with unsealed source radiotherapy in which a therapeutic radionuclide (radioisotope) is injected into the body to chemically localize to the tissue requiring destruction. It also contrasts to EBRT, in which high-energy x-rays (or occasionally gamma-rays from a radioisotope like cobalt-60) are directed at the tumour from outside the body. Brachytherapy instead involves the precise placement of short-range radiation-sources (radioisotopes) directly at the site of the cancerous tumour. These are enclosed in a protective capsule or wire, which allows the ionizing radiation to escape to treat and kill surrounding tissue but prevents the charge of radioisotope from moving or dissolving in body fluids. The capsule may be removed later, or (with some radioisotopes) it may be allowed to remain in place.A key feature of brachytherapy is that the irradiation affects only a very localized area around the radiation sources. Exposure to radiation of healthy tissues farther away from the sources is therefore reduced. In addition, if the patient moves or if there is any movement of the tumour within the body during treatment, the radiation sources retain their correct position in relation to the tumour. These characteristics of brachytherapy provide advantages over EBRT - the tumour can be treated with very high doses of localised radiation whilst reducing the probability of unnecessary damage to surrounding healthy tissues.A course of brachytherapy can be completed in less time than other radiotherapy techniques. This can help reduce the chance for surviving cancer cells to divide and grow in the intervals between each radiotherapy dose. Patients typically have to make fewer visits to the radiotherapy clinic compared with EBRT, and the treatment is often performed on an outpatient basis. This makes treatment accessible and convenient for many patients. These features of brachytherapy mean that most patients are able to tolerate the brachytherapy procedure very well.Brachytherapy represents an effective treatment option for many types of cancer. Treatment results have demonstrated that the cancer cure rates of brachytherapy are either comparable to surgery and EBRT or are improved when used in combination with these techniques. In addition, brachytherapy is associated with a low risk of serious adverse side effects.The global market for brachytherapy reached US$680 million in 2013, of which the High-Dose Rate (HDR) and LDR segments accounted for 70%. Microspheres and electronic brachytherapy commanded the remaining 30%. The brachytherapy market is expected to reach over US$2.4 billion in 2030, growing by 8% annually, mainly driven by the microspheres market as well as electronic brachytherapy, which is gaining significant interest worldwide as a user-friendly technology.
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