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Lipid Metabolism 1. What has a higher stored energy potential per
Lipid Metabolism 1. What has a higher stored energy potential per

... 2. Acetyl CoA units are shuttled out of the mitochondria via citrate (which reacts with CoA in the cytosol to produce acetyl CoA and malate). The carbon units are returned to the mitochondria via pyruvate (following decarboxylation of malate). 3. Excess acetyl CoA is converted to ketone bodies when ...
1 Enzymes: The Biological Catalysts Definition: Enzymes are
1 Enzymes: The Biological Catalysts Definition: Enzymes are

... These are compounds which compete with the natural substrate for the biding with the active site of the enzyme, therefore decreasing the catalytic activity of the enzyme, e.g. the enzyme succinate dehydrogenase (SDH) oxidizes succinic acid to fumaric acid. Addition of malonic acid, which has a chemi ...
AKA TCA CYCLE, KREB`S CYCLE
AKA TCA CYCLE, KREB`S CYCLE

... •succinate transported to mito where it is converted to oxaloactate via TCA •acetate can be used as C source via glyoxylate cycle: 1st converted to acetyl CoA by acetate thiokinase acetate + CoA-SH + ATP ----> acetyl CoA + AMP + PPi 4. glyoxylate cycle and also some of the β oxidation of FAs (fatty ...
Chapter 5: Nucleic Acids, etc. Nucleotides and Derivatives Nucleic
Chapter 5: Nucleic Acids, etc. Nucleotides and Derivatives Nucleic

... (1) Monomeric units of nucleic acids (2) Nucleoside triphosphates (ATP) are “energy rich” end products of most energy-releasing pathways AND are consumed in energy-requiring processes (3) Regulators of metabolic pathways and metabolic processes ...
GPI Anchor
GPI Anchor

... 3. The transamidase reaction is carried out by a multiprotein complex that has as yet not been isolated in its intact form. 4. The carboxy-terminal signal peptide which is cleaved prior to binding of the GPI, consisting 15–30 amino acids, has structural similarities to the NH2-terminal peptide that ...
PDF - Biochemical Journal
PDF - Biochemical Journal

... A 3CI isotope-dilution method which provides an Institute of Animal Phy8iology, Babraham, Camadequate standard of reference for evaluation of bridge) other methods has been developed (Cotlove & The effects on glutamate dehydrogenase of Green, 1958). The present method involves comacetate (PMA) (Hell ...
Text - PDF
Text - PDF

... aquacultured Oncorhynchus mykiss are not much different from those of other rapidly growing farm animals. He found that rainbow trout was utilized either a dispensable amino acids mixture or alanine alone as effectively as casein as energy source. In the present study seven amino acids (proline, ala ...
How metabolites modulate metabolic flux
How metabolites modulate metabolic flux

... induce a high glycolytic flux. Since serine is derived from the glycolytic intermediate glycerate 3-phosphate, increased glycolysis would increase the flux to serine biosynthesis, assuming all enzymes are solely regulated by substrate concentrations. However, the end product of both pathways is eith ...
CHEM 32-002
CHEM 32-002

... b) Is this triglyceride a solid, a liquid, or a gas at room temperature? Circle the correct choice. 13) (5 points) Starch is made up of two different polysaccharides: amylose and amylopectin. How are their chemical structures different from one another? ...
Enzymology - Angelfire
Enzymology - Angelfire

... the better model of enzymatic action, particular enzymes usually catalyze a very limited range of reactions. This is called enzyme specificity. ...
1 - u.arizona.edu
1 - u.arizona.edu

... Inhibition by citrate and ATP - liver glycolysis is regulated by pyruvate kinase; regulation of this enzyme coordinates with control of PFK-1 - citrate and ATP are allosteric inhibitors of both enzymes - prevent accumulation of phosphorylated intermediates Allosteric activation - pyruvate kinase act ...
SAM Teacher`s Guide Four Levels of Protein Structure - RI
SAM Teacher`s Guide Four Levels of Protein Structure - RI

... the importance of hydrogen bonding in stabilizing these structures.   • Identify tertiary structure as the final folding pattern of a protein and infer that  mistakes in folding are responsible for many human diseases.  • Explain that quaternary structure occurs when a protein is composed of more  t ...
Chapter 7 Study Guide
Chapter 7 Study Guide

... Metabolism is the sum of cellular chemical and physical activities. It consists of anabolism, synthetic reactions that convert small molecules into large molecules, and catabolism, in which large molecules are degraded and energy is produced. Metabolism is made possible by organic catalysts, or enzy ...
Preference for and learning of amino acids in larval
Preference for and learning of amino acids in larval

... Amino acids are required for protein synthesis and are therefore essential for all organisms. Animals either need to break down ingested protein to obtain amino acids, or synthesize them themselves. Thus, the internal monitoring of amino acid demand and the organization of behaviour to secure their ...
Biochemical Engineering Prof. Dr. Rintu Banerjee Department of
Biochemical Engineering Prof. Dr. Rintu Banerjee Department of

... arginine, Valine, Histidine, Isoleucine, Leucine, Lysine, Methionine, Phenylalanine, threonine and tryptophan. So, these are the amino acids which cannot be synthesized within the body system. And that is the reason it these amino acids are replaced or it is the demand is meet through diet or food. ...
Scholarly Interest Report
Scholarly Interest Report

... My current interest is the theoretical basis for ammonia detoxication in vertebrate liver. This ammonia may be of either hepatic or extrahe- patic origin. Liver tissue is the site of gluconeogenesis in higher vertebrates and, during this process, amino acids are deaminated, forming ammonia. Extrahep ...
Nutritional Importance of Proteins
Nutritional Importance of Proteins

... This is primarily due to insufficient intake of proteins, as the diet of a weaning child mainly consists of carbohydrates. ...
Regeneration of NAD+ Lactic Acid Fermentation
Regeneration of NAD+ Lactic Acid Fermentation

... • Mechanism involves two covalent intermediates with the enzyme: • Addition of pyruvate to TPP and loss of CO2 forms hydroxyethyl TPP. • (This same intermediate is formed by pyruvate decarboxylase in yeast alcoholic fermentation). ...
Name: Date: Period: ______ Must-Knows: Unit 6 (Enzymes and Cell
Name: Date: Period: ______ Must-Knows: Unit 6 (Enzymes and Cell

... An experiment to measure the rate of respiration in crickets and mice at 10°C and 25°C was performed using a respirometer, an apparatus that measures changes in gas volume. Respiration was measured in mL of O2 consumed per gram of organism over several five-minute trials and the following data were ...
Document
Document

... In most aerobic organisms, pyruvate continues in the formation of Acetyl CoA and NADH that follows into the Krebs cycle and ...
Chemistry of Natural Compounds
Chemistry of Natural Compounds

... compounds can be divided into two main classes: primary metabolites and secondary metabolites; primary metabolites are the fundamental building blocks common to all living matter. Secondary metabolites reflect the differentiation of the species and are natural products typical of only specific group ...
An enlarged largest subunit or Plasmodium falciparum RNA
An enlarged largest subunit or Plasmodium falciparum RNA

... sequences of clone gl5 and the cDNA clones were colinear (Fig. 1C. and ID.). Oligonucleotide probes B and C, derived from the 5' region of clone gl5, hybridized with a 12 kb genomic Xbal fragment (Fig. 2B.). Probe B and C selected a clone, XI, from a Xbal genomic DNA library. Clone XI contained the ...
Quantum Mechanical Model for Information Transfer from DNA to
Quantum Mechanical Model for Information Transfer from DNA to

... genetic information is conserved, and models DNA as the sender and proteins as the receiver of this information. Genetic information for protein synthesis is encoded in nucleotide triplets (codons). Since 64 possible codons exist, a 64-dimensional Hilbert space, for which the codons are the base st ...
medbiochem exam, 1999
medbiochem exam, 1999

... 3. A patient complained of painful cramps in her legs during exercise. Her patient history also revealed that she experienced easy fatigability. Which of the following are consistent with these observations? A. The patient is diabetic. B. The patient is missing the enzyme glucose-6-phosphatase C. Th ...
VOLATILE COMPOUNDS AND AMINO ACIDS IN CHEESE
VOLATILE COMPOUNDS AND AMINO ACIDS IN CHEESE

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Amino acid synthesis

Amino acid synthesis is the set of biochemical processes (metabolic pathways) by which the various amino acids are produced from other compounds. The substrates for these processes are various compounds in the organism's diet or growth media. Not all organisms are able to synthesise all amino acids. Humans are excellent example of this, since humans can only synthesise 11 of the 20 standard amino acids (aka non-essential amino acid), and in time of accelerated growth, arginine, can be considered an essential amino acid.A fundamental problem for biological systems is to obtain nitrogen in an easily usable form. This problem is solved by certain microorganisms capable of reducing the inert N≡N molecule (nitrogen gas) to two molecules of ammonia in one of the most remarkable reactions in biochemistry. Ammonia is the source of nitrogen for all the amino acids. The carbon backbones come from the glycolytic pathway, the pentose phosphate pathway, or the citric acid cycle.In amino acid production, one encounters an important problem in biosynthesis, namely stereochemical control. Because all amino acids except glycine are chiral, biosynthetic pathways must generate the correct isomer with high fidelity. In each of the 19 pathways for the generation of chiral amino acids, the stereochemistry at the α-carbon atom is established by a transamination reaction that involves pyridoxal phosphate. Almost all the transaminases that catalyze these reactions descend from a common ancestor, illustrating once again that effective solutions to biochemical problems are retained throughout evolution.Biosynthetic pathways are often highly regulated such that building-blocks are synthesized only when supplies are low. Very often, a high concentration of the final product of a pathway inhibits the activity of enzymes that function early in the pathway. Often present are allosteric enzymes capable of sensing and responding to concentrations of regulatory species. These enzymes are similar in functional properties to aspartate transcarbamoylase and its regulators. Feedback and allosteric mechanisms ensure that all twenty amino acids are maintained in sufficient amounts for protein synthesis and other processes.
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