SUPPLEMENTAL DATA FOR DUPLICATED SACCHAROMYCES
... glycogen synthase kinase-3 (GSK-3) homologues. MCK1 is involved in control of chromosome segregation and regulation of entry into meiosis ([9-11]; for review see [12]). MCK1 down-regulates pyruvate kinase [13] that involves inhibition of a cAMPdependent protein kinase [14]. MCK1 also has a role in r ...
... glycogen synthase kinase-3 (GSK-3) homologues. MCK1 is involved in control of chromosome segregation and regulation of entry into meiosis ([9-11]; for review see [12]). MCK1 down-regulates pyruvate kinase [13] that involves inhibition of a cAMPdependent protein kinase [14]. MCK1 also has a role in r ...
Supplementary document Trehalose/2
... distribution of rates among sites as previously suggested (Minegishi et al 2010). Support ...
... distribution of rates among sites as previously suggested (Minegishi et al 2010). Support ...
General Biochemistry 115:404/504 Lecture and Exam Schedule
... a. Carbohydrate metabolism (TCA cycle, gluconeogenesis and glycolysis) b. Lipid metabolism c. Amino acid and nitrogen metabolism 2. The production of cellular energy (ATP) including oxidative phosphorylation and photosynthesis. 3. DNA replication and the central dogma 4. Regulation of gene expressio ...
... a. Carbohydrate metabolism (TCA cycle, gluconeogenesis and glycolysis) b. Lipid metabolism c. Amino acid and nitrogen metabolism 2. The production of cellular energy (ATP) including oxidative phosphorylation and photosynthesis. 3. DNA replication and the central dogma 4. Regulation of gene expressio ...
Enzymes - Ústav lékařské biochemie a laboratorní diagnostiky
... and perform a test for starch using Lugol solution (pre-diluted with water: 4 drops/10 ml of water). Evaluation: Indicate to the table in your lab report where the cleavage of the substrate occurred using symbols + (substrate cleaved) or − (substrate not cleaved). ...
... and perform a test for starch using Lugol solution (pre-diluted with water: 4 drops/10 ml of water). Evaluation: Indicate to the table in your lab report where the cleavage of the substrate occurred using symbols + (substrate cleaved) or − (substrate not cleaved). ...
Lecture 22-Lutz
... • late 1990’s - inhibitors designed that preferentially bind COX-2, are equally effective as NSAIDs, but are reported to cause less GI damage. • 1998/1999 - Celebrex and Vioxx approved by FDA for osteoarthritis and rheumatoid arthritis. ...
... • late 1990’s - inhibitors designed that preferentially bind COX-2, are equally effective as NSAIDs, but are reported to cause less GI damage. • 1998/1999 - Celebrex and Vioxx approved by FDA for osteoarthritis and rheumatoid arthritis. ...
Chapter 13 Carbohydrate Metabolism
... mole of glucose that is converted to pyruvate. • Other sugars are also digested in glycolysis: – Fructose enters glycolysis as dihydroxyacetone phosphate and glyceraldehyde-3-phosphate. – Galactose is isomerized to form glucose-6phosphate. ...
... mole of glucose that is converted to pyruvate. • Other sugars are also digested in glycolysis: – Fructose enters glycolysis as dihydroxyacetone phosphate and glyceraldehyde-3-phosphate. – Galactose is isomerized to form glucose-6phosphate. ...
Intro to Carbon-based Molecules: Organic Chemistry
... The nature and arrangement of amino acids in the active site make it specific for only one type of substrate (the reactant being catalyzed). Copyright Cmassengale ...
... The nature and arrangement of amino acids in the active site make it specific for only one type of substrate (the reactant being catalyzed). Copyright Cmassengale ...
Lipids are biological molecules that are insoluble, or only sparingly
... Fatty acids can be desaturated by enzymes that insert double bonds between the carbons 9 and 10 from the COOH end. Desaturation can also occur closer to the COOH end, but not further away (hence linoleic acid and linolenic acid must be taken in the diet). F. Regulation of fatty acid synthesis 1. Pyr ...
... Fatty acids can be desaturated by enzymes that insert double bonds between the carbons 9 and 10 from the COOH end. Desaturation can also occur closer to the COOH end, but not further away (hence linoleic acid and linolenic acid must be taken in the diet). F. Regulation of fatty acid synthesis 1. Pyr ...
Document
... two molecules ATP (and NADH * ) • Occurs in cytoplasm * glycolysis has two stages: 1. glycolytic pathway (Glucose to pyruvate) ,including two phases 2.Fermentation phase 发酵 (pyruvate to lactate) ...
... two molecules ATP (and NADH * ) • Occurs in cytoplasm * glycolysis has two stages: 1. glycolytic pathway (Glucose to pyruvate) ,including two phases 2.Fermentation phase 发酵 (pyruvate to lactate) ...
Enzyme Mechanisms
... Most growth factors function via a pathway that involves these enzymes In absence of ligand, 2 nearby tyr kinase molecules are separated Upon substrate binding they come together, form a dimer 09/30/08 Biochemistry:Transport; Nucleic Acids ...
... Most growth factors function via a pathway that involves these enzymes In absence of ligand, 2 nearby tyr kinase molecules are separated Upon substrate binding they come together, form a dimer 09/30/08 Biochemistry:Transport; Nucleic Acids ...
Lipidomics in Cell Regulation
... proton-gradients Ensure a stable cellular environment Provides a 2-D space for efficient chemical reaction The lipids creates an optimal environment for protein function in the membrane More than 300 lipid species are found in the plasma membrane ...
... proton-gradients Ensure a stable cellular environment Provides a 2-D space for efficient chemical reaction The lipids creates an optimal environment for protein function in the membrane More than 300 lipid species are found in the plasma membrane ...
Chapt 2-9 Practice Problem Answers
... number of molecules required but also the number of moles required. It also explains why moles can be substituted for molecules in such equations. Question 4: Some students have difficulty understanding that a solution’s concentration or molarity does not change if you aliquot or subdivide the solut ...
... number of molecules required but also the number of moles required. It also explains why moles can be substituted for molecules in such equations. Question 4: Some students have difficulty understanding that a solution’s concentration or molarity does not change if you aliquot or subdivide the solut ...
Metabolism of Mollicutes: the Embden-Meyerhof
... using the Bio-Rad protein dye reagent concentrate with BSA as the standard. All other enzymes, cofactors and reagents were obtained from Sigma. Details ofindividual assays. (i) Hexokinase (EC 2.7.1 . l ) was assayed by the method of Chou & Wilson (1975). (ii) Glucose-6-phosphate (G6P) dehydrogenase ...
... using the Bio-Rad protein dye reagent concentrate with BSA as the standard. All other enzymes, cofactors and reagents were obtained from Sigma. Details ofindividual assays. (i) Hexokinase (EC 2.7.1 . l ) was assayed by the method of Chou & Wilson (1975). (ii) Glucose-6-phosphate (G6P) dehydrogenase ...
A tale of two functions: enzymatic activity and
... activity. Carboxyltransferase binds the coding regions of both subunit mRNAs and inhibits translation, an inhibition that is relieved by the substrate acetyl-CoA. mRNA binding reciprocally inhibits catalytic activity. Preferential binding of carboxyltransferase to RNA in situ was shown using fluores ...
... activity. Carboxyltransferase binds the coding regions of both subunit mRNAs and inhibits translation, an inhibition that is relieved by the substrate acetyl-CoA. mRNA binding reciprocally inhibits catalytic activity. Preferential binding of carboxyltransferase to RNA in situ was shown using fluores ...
Sialic Acid Linkage Analysis Kit
... The linkage specificities of the Sialidases from S.pneumoniae and C.perfringens are valid for sialic acid residues situated at the non-reducing terminus of oligosaccharides. For oligosaccharides such as GM1 or DSNT (see structures above) in which the sialic acid is linked to an internal residue (a r ...
... The linkage specificities of the Sialidases from S.pneumoniae and C.perfringens are valid for sialic acid residues situated at the non-reducing terminus of oligosaccharides. For oligosaccharides such as GM1 or DSNT (see structures above) in which the sialic acid is linked to an internal residue (a r ...
Enzyme Lecture PowerPoint
... versions in smaller file sizes, such as PowerPoint Shows and Portable Document Format (.pdf), for ease of printing. • Images used on this resource, and on the SPO website are, wherever possible, credited and linked to their source. Any words underlined and appearing in blue are links that can be cli ...
... versions in smaller file sizes, such as PowerPoint Shows and Portable Document Format (.pdf), for ease of printing. • Images used on this resource, and on the SPO website are, wherever possible, credited and linked to their source. Any words underlined and appearing in blue are links that can be cli ...
Inflammation and ER Stress Regulate Branched
... 2A). We also observed a dose-dependent down-regulation with varying concentrations of TNF␣ (Figure 2B) and that other inflammatory factors (IL-6, IL-1, and IFN␥) similarly down-regulated BCAA gene expression (Figure 2C). Furthermore, the expression of branchedchain amino-acid transaminase 2 (Bcat2) ...
... 2A). We also observed a dose-dependent down-regulation with varying concentrations of TNF␣ (Figure 2B) and that other inflammatory factors (IL-6, IL-1, and IFN␥) similarly down-regulated BCAA gene expression (Figure 2C). Furthermore, the expression of branchedchain amino-acid transaminase 2 (Bcat2) ...
RESEARCH ARTICLES Characterization of the Long
... 1974). Fleas show a transformation of the multifaceted eyes and ommatidia of most insects, replaced instead with heavily sclerotized, atypical ocelli, or ‘‘eyespots,’’ or in some cases, a complete absence of any eye at all (Dunnet and Mardon 1991). The species used in our analysis exhibit a diversit ...
... 1974). Fleas show a transformation of the multifaceted eyes and ommatidia of most insects, replaced instead with heavily sclerotized, atypical ocelli, or ‘‘eyespots,’’ or in some cases, a complete absence of any eye at all (Dunnet and Mardon 1991). The species used in our analysis exhibit a diversit ...
The Study of the Content of N-Acetylneuraminic Acids in Membranes
... receptor reactions, formation and storage of memory. The main role in these processes is attributed to the presence in their structure of neuraminic acids. Neuraminic (sialic) acids are polyfunctional compounds with strong acid properties. As a rule, they are not found in the free form, they are inc ...
... receptor reactions, formation and storage of memory. The main role in these processes is attributed to the presence in their structure of neuraminic acids. Neuraminic (sialic) acids are polyfunctional compounds with strong acid properties. As a rule, they are not found in the free form, they are inc ...
L22_GlngBox
... Transport of FA: Mitochondria • Malonyl CoA is a very strong inhibitor of CAT-I • CAT-I is the key regulator of fat oxidation - once FA gets into the mitochondria, it will be oxidized (i.e. the only fate of mitochondrial FA-CoA is oxidation) • Alternative fate of FA-CoA in the cytoplasm is esterifi ...
... Transport of FA: Mitochondria • Malonyl CoA is a very strong inhibitor of CAT-I • CAT-I is the key regulator of fat oxidation - once FA gets into the mitochondria, it will be oxidized (i.e. the only fate of mitochondrial FA-CoA is oxidation) • Alternative fate of FA-CoA in the cytoplasm is esterifi ...
Organic Macromolecules and the Genetic Code
... Now, here is one of the central problems of biology. Much of what is going on in a cell, as we have seen, is carried out by proteins. There are all kinds of proteins, depending on the sequence of their 20 amino acids: Ala-Ala-Gly-Leu-Ser-. . . Will be entirely different from Gly-Ala-Leu-Ser-Ala- . ...
... Now, here is one of the central problems of biology. Much of what is going on in a cell, as we have seen, is carried out by proteins. There are all kinds of proteins, depending on the sequence of their 20 amino acids: Ala-Ala-Gly-Leu-Ser-. . . Will be entirely different from Gly-Ala-Leu-Ser-Ala- . ...
Biological Radical Sulfur Insertion Reactions
... Galactose oxidase is a monomeric copper-containing enzyme that catalyzes the stereospecific oxidation of primary alcohols to their corresponding aldehydes.37 The crystal structure of the enzyme from Fusarium sp. shows a thioether bond resulting from the covalent cross-link between Sγ of a cysteine r ...
... Galactose oxidase is a monomeric copper-containing enzyme that catalyzes the stereospecific oxidation of primary alcohols to their corresponding aldehydes.37 The crystal structure of the enzyme from Fusarium sp. shows a thioether bond resulting from the covalent cross-link between Sγ of a cysteine r ...
