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Diffusion-weighted MRI of urinary bladder and prostate cancers
Diffusion-weighted MRI of urinary bladder and prostate cancers

... important in the assessment of disease response to treatment methods. Conventional assessment by measuring lesion size is insensitive to early treatment-related changes (22). The present study has several potential limitations. First, the patient population was relatively small. Second, not all of t ...
Interfractional and intrafractional setup errors in radiotherapy for
Interfractional and intrafractional setup errors in radiotherapy for

... to 160 degrees, with a nominal scan dose of 10–16 mGy. Pre-correction CBCT (CBCT at initial setup) for each fraction should be acquired and automatically matched with the planning CT to obtain the shifts of initial tumor position in the left-right (X), superior-inferior (Y) and anterior-posterior (Z ...
The Measurement, Reporting, and Management of
The Measurement, Reporting, and Management of

... technologies; for consistency, the term “helical” will be used throughout). The introduction of dual-slice systems in 1994 and multislice systems in 1998 (four detector arrays along the z-axis) has further accelerated the implementation of many new clinical applications1–3. The number of slices, or ...
Two−dimensional longitudinal strain for the assessment of the left
Two−dimensional longitudinal strain for the assessment of the left

... mind that these are not identical, interchangeable parameters, but that they describe different components of LV systolic function. The LVEF is a derivative of volume change, dependent on haemodynamic status, such as volaemia, preload and afterload, as well as on myocardial contractility including c ...
View Full PDF - Bioscience Reports
View Full PDF - Bioscience Reports

... help elucidate the penile venous anatomy [8]. However, conventional cavernosography does not always reveal precise penile veins of interest because due to overlapping by other veins, bone or cavernous body. The obstruction of visualization of these structures also makes it difficult to show the orig ...
Percentage Insula Ribbon Infarction of >50% Identifies Patients
Percentage Insula Ribbon Infarction of >50% Identifies Patients

... response to both intravenous and intra-arterial treatment; specifically, a large pretreatment DWI lesion is recognized as a clinically useful marker for poor treatment response.3,4 Clinical outcome is more variable in patients with small infarcts (⬍70 mL).3 An imaging marker that can more reliably p ...
Cancer risks associated with external radiation from diagnostic
Cancer risks associated with external radiation from diagnostic

... the severity of the outcome is not related to the dose.2 For many years, radiation dose-related cancer risks at low doses were generally estimated from results of the follow-up studies of the atomic bomb survivors and of patients treated with moderate- to high-dose radiation. Major national and inte ...
Spleen Fine Needle Aspiration
Spleen Fine Needle Aspiration

... Lymphoma: most common spleen malignancy. The CT appearances is similar to a variety of splenic pathologies: homogeneus enlargment without a discrete mass, solitary mass, multifocal mass and diffuse infiltration. ...
Role of Multiparametric MRI in the diagnosis of Prostate Cancer
Role of Multiparametric MRI in the diagnosis of Prostate Cancer

... hypointensity in the ADC map. Because of the ADC quantitative values obtained, it has recently been possible to stratify CaP aggressiveness, by correlation between ADC values and Gleason score [26]. The Dynamic Contrast Enhancement (DCE) perfusion examination, is a sequence that utilizes the use of ...
Understanding Radiation Units
Understanding Radiation Units

... A summation of the tissue equivalent doses, each multiplied by the appropriate tissue weighting factor: ...
Image Guided Radiation Therapy: Benefits and Risks, Certainties
Image Guided Radiation Therapy: Benefits and Risks, Certainties

...  “Image-guided radiotherapy (IGRT) makes use of many different imaging techniques, using modalities ranging from portal imaging to fluoroscopy to megavoltage cone-beam CT and following regimens as simple as a single setup image or as complex as intrafraction tumor tracking.”1 AAPM TG-75 (2007) ...
PET/SPECT imaging agents for neurodegenerative diseases
PET/SPECT imaging agents for neurodegenerative diseases

... Tc, which emits medium energy photons (140 keV), are useful for SPECT imaging, while positron emitting isotopes, such as 18F, emit a positron, which collides with nearby electrons. The resulting annihilation reaction between a positron and an electron produces two 511 keV photons for PET imaging. Mo ...
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... Especially scans for pulmonary embolism in young women Dose to breasts may be up to 19 times that from a mammogram Strategy for dose reduction: be selective ...
Guidelines for Education and Training of Medical Physicists
Guidelines for Education and Training of Medical Physicists

... In this document we refer to Medical Physicists working (or training for a career) in the radiotherapy speciality as ‘medical physicists in radiotherapy’. Given the wide variety of professional titles in use throughout Europe, we will use the title RTT (Radiation Therapy Technologists) to refer to t ...
Comparison between 99mTc-sestamibi gated myocardial perfusion
Comparison between 99mTc-sestamibi gated myocardial perfusion

... Seyed Hashem Danesh-Sani1, Seyed Rasoul Zakavi2, Leyla Oskoueian1, Vahid-Reza Dabbagh Kakhki2 Department of Cardiovascular Diseases, Imam Reza Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran Nuclear Medicine Research Center, Ghaem Hospital, Faculty of Medicine, M ...


... begin Phase II human clinical trials in H2 2012 with VasoPET expected to begin a Phase Ia trial in Q1 2013. 4.) Attractive Space for M&A: We note that the molecular imaging space has been active for M&A deals such as Eli Lilly’s (NYSE:LLY) acquisition of Avid Radiopharmaceuticals Amyvid™ [18F ] flor ...
The Radiologic Assessment of Trigeminal Neuropathy
The Radiologic Assessment of Trigeminal Neuropathy

... In this report we examined the clinical and radiologic records of 76 patients in order to address the following questions. First, how accurate is the preradiologic clinical evaluation in localizing the lesion affecting the fifth cranial nerve and can it be used to focus the imaging process to precis ...
position paper techniques and technologies in radiation oncology
position paper techniques and technologies in radiation oncology

... (radiation) is delivered using various specifically chosen techniques to deliver a prescribed radiation dose to the target (such as a tumour) while ensuring that the radiation dose to the surrounding normal tissues is as low as possible.[1] The overall optimal radiation therapy utilisation rate for ...
Use of Echocardiography to Evaluate the Cardiac Effects of
Use of Echocardiography to Evaluate the Cardiac Effects of

... irreversible myocardial cell dysfunction, potentially leading to heart failure (HF) and death, with treatment, if not recognized early. Presently, chemotherapy-induced cardiotoxicity limits the ability to reduce morbidity and mortality associated with cancers throughout the world. Chemotherapy-induc ...
Introduction to Radiology - UNC School of Medicine
Introduction to Radiology - UNC School of Medicine

... contrast induced nephropathy Allergy issues Power injected and causes vaso-vagal reactions (NPO) ...
Dental Radiographic Examinations
Dental Radiographic Examinations

... asymptomatic patients, combined with selected periapical radiographs for symptomatic patients, can result in a 43 percent reduction in the number of radiographs taken without a clinically consequential increase in the rate of undiagnosed disease.6,7 The development and progress of many oral conditio ...
Dental Radiographic Examinations
Dental Radiographic Examinations

... asymptomatic patients, combined with selected periapical radiographs for symptomatic patients, can result in a 43 percent reduction in the number of radiographs taken without a clinically consequential increase in the rate of undiagnosed disease.6,7 The development and progress of many oral conditio ...
3 JCI dosimetry for CT
3 JCI dosimetry for CT

... radiation dose index (CTDIvol, DLP, or size-specific dose estimate [SSDE]) on every study produced during a diagnostic computed tomography (CT) examination. The radiation dose index must be exam specific, summarized by series or anatomic area, and documented in a retrievable format. The [critical ...
comparison of localization performance with implanted fiducial
comparison of localization performance with implanted fiducial

... (CBCT)– based setup corrections as compared with orthogonal megavoltage (MV) portal image-based corrections for patients undergoing external-beam radiotherapy of the prostate. Methods and Materials: Daily cone-beam CT volumetric images were acquired after setup for patients with three intraprostatic ...
New York University School of Medicine VASCULAR AND INTERVENTIONAL RADIOLOGY FELLOWSHIP
New York University School of Medicine VASCULAR AND INTERVENTIONAL RADIOLOGY FELLOWSHIP

... The NYU VIR fellowship program requires its fellows to obtain competencies in the 6 areas below to the level expected of a new practitioner: a. Patient Care that is compassionate, appropriate, and effective for the treatment of health problems and the promotion of health. b. Medical Knowledge about ...
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Neutron capture therapy of cancer



Neutron capture therapy (NCT) is a noninvasive therapeutic modality for treating locally invasive malignant tumors such as primary brain tumors and recurrent head and neck cancer. It is a two step procedure: first, the patient is injected with a tumor localizing drug containing a non-radioactive isotope that has a high propensity or cross section (σ) to capture slow neutrons. The cross section of the capture agent is many times greater than that of the other elements present in tissues such as hydrogen, oxygen, and nitrogen. In the second step, the patient is radiated with epithermal neutrons, which after losing energy as they penetrate tissue, are absorbed by the capture agent which subsequently emits high-energy charged particles, thereby resulting in a biologically destructive nuclear reaction (Fig.1).All of the clinical experience to date with NCT is with the non-radioactive isotope boron-10, and this is known as boron neutron capture therapy (BNCT). At this time, the use of other non-radioactive isotopes, such as gadolinium, has been limited, and to date, it has not been used clinically. BNCT has been evaluated clinically as an alternative to conventional radiation therapy for the treatment of malignant brain tumors (gliomas), and more recently, recurrent, locally advanced head and neck cancer.
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