AG2010 lecture 1_basic genetics
... • Lethal genes • Pleiotropy Single mutant gene resulting in multiple different phenotypes e.g. S allele of sickle cell anemia ...
... • Lethal genes • Pleiotropy Single mutant gene resulting in multiple different phenotypes e.g. S allele of sickle cell anemia ...
Genetics Vocabulary
... Definition: Basic, functional units of heredity, each occupying a specific place on a chromosome. Genes are represented by a pair of letters. Heterozygous or Homozygous Context: In 1909 a Danish botanist coined the term “genes” to describe Mendel’s factors in inherited traits. heredity Definition: G ...
... Definition: Basic, functional units of heredity, each occupying a specific place on a chromosome. Genes are represented by a pair of letters. Heterozygous or Homozygous Context: In 1909 a Danish botanist coined the term “genes” to describe Mendel’s factors in inherited traits. heredity Definition: G ...
Quiz 3 Thursday 4-5 Answer Key
... if it’s the same gene the F1 worms will be large. If the mutations are in different genes, the F1 will be wild type. c) You cross one of your large worms to the unc-5 IV; dpy-11 V; lon-2 X strain. When you look at the F2 worms, ¼ of the unc worms are large, and ¼ of the lon worms are large. However, ...
... if it’s the same gene the F1 worms will be large. If the mutations are in different genes, the F1 will be wild type. c) You cross one of your large worms to the unc-5 IV; dpy-11 V; lon-2 X strain. When you look at the F2 worms, ¼ of the unc worms are large, and ¼ of the lon worms are large. However, ...
Whole genome sequence analysis of Mycobacteria tuberculosis
... resistant to the drugs used to treat the disease threatens to derail efforts to control tuberculosis, which remains a major global public health problem. Whole-genome sequencing of M. tuberculosis clinical isolates is facilitating the characterisation of mutations associated with drug resistance. Th ...
... resistant to the drugs used to treat the disease threatens to derail efforts to control tuberculosis, which remains a major global public health problem. Whole-genome sequencing of M. tuberculosis clinical isolates is facilitating the characterisation of mutations associated with drug resistance. Th ...
Mutations in the Anopheles gambiae Pink
... that were not in the pink-eye gene were crossed to one another for further complementation and intragenic recombination analysis as above. In order to determine if an epistatic interaction between the eye-color mutations and collarless existed, female mutants from uniformly collarless phenotype stra ...
... that were not in the pink-eye gene were crossed to one another for further complementation and intragenic recombination analysis as above. In order to determine if an epistatic interaction between the eye-color mutations and collarless existed, female mutants from uniformly collarless phenotype stra ...
Cross-species gene transfer: a major factor in evolution?
... number of unexpected experimental results transfer of genes from one species to another may be a major factor in have just been published which were either macroevolutionary change. predicted by the theory or are pertinent to it. Here I briefly summarize the central idea, and review the information, ...
... number of unexpected experimental results transfer of genes from one species to another may be a major factor in have just been published which were either macroevolutionary change. predicted by the theory or are pertinent to it. Here I briefly summarize the central idea, and review the information, ...
BASIC GENETICS - Makerere University Courses
... determination, causes and consequences of mutation. Specific learning outcomes: At the end of the course, students should be able to: 1. compare and contrast Pre-Mendelian and Mendelian theories of inheritance 2. apply Mendel’s first and second laws of inheritance to solve related genetic problems 3 ...
... determination, causes and consequences of mutation. Specific learning outcomes: At the end of the course, students should be able to: 1. compare and contrast Pre-Mendelian and Mendelian theories of inheritance 2. apply Mendel’s first and second laws of inheritance to solve related genetic problems 3 ...
12.3 DNA Replication
... An enzyme called ______________ compensates for this problem by adding short, repeated DNA sequences to telomeres, _______________________ the chromosomes slightly and making it less likely that important gene sequences will be lost from the telomeres during replication. ...
... An enzyme called ______________ compensates for this problem by adding short, repeated DNA sequences to telomeres, _______________________ the chromosomes slightly and making it less likely that important gene sequences will be lost from the telomeres during replication. ...
Protein synthesis File
... Q. How is this different from DNA replication? You may find it helpful to consider: exposure of the DNA to act as a template; which strands are copied; the nucleotides involved and any differences in their composition, e.g. pentose sugar involved; complementary pairing; other features, e.g. nature ...
... Q. How is this different from DNA replication? You may find it helpful to consider: exposure of the DNA to act as a template; which strands are copied; the nucleotides involved and any differences in their composition, e.g. pentose sugar involved; complementary pairing; other features, e.g. nature ...
AMINO ACID: STRUCTURE AND CLASSIFICATION.
... • These are amide linkages between the α-carboxyl group of one amino acid and the α-amino group of another ...
... • These are amide linkages between the α-carboxyl group of one amino acid and the α-amino group of another ...
Secondary structure prediction
... Chou and Fasman (1974) developed an algorithm based on the frequencies of amino acids found in a helices, b-sheets, and turns. Proline: occurs at turns, but not in a helices. GOR (Garnier, Osguthorpe, Robson): related algorithm Modern algorithms: use multiple sequence alignments and achieve higher s ...
... Chou and Fasman (1974) developed an algorithm based on the frequencies of amino acids found in a helices, b-sheets, and turns. Proline: occurs at turns, but not in a helices. GOR (Garnier, Osguthorpe, Robson): related algorithm Modern algorithms: use multiple sequence alignments and achieve higher s ...
013368718X_CH17_267-284.indd
... mutations, genetic recombination during sexual reproduction, and lateral gene transfer. A mutation is any change in a sequence of DNA. Most heritable differences are due to genetic recombination during sexual reproduction. This occurs during meiosis when each chromosome in a pair moves independently ...
... mutations, genetic recombination during sexual reproduction, and lateral gene transfer. A mutation is any change in a sequence of DNA. Most heritable differences are due to genetic recombination during sexual reproduction. This occurs during meiosis when each chromosome in a pair moves independently ...
DNA Sequencing and Gene Analysis
... • The four dNTPs are added one at a time, with apyrase degradation and washing in between. • The amount of light released is proportional to the number of bases added. Thus, if the sequence has 2 A’s in a row, both get added and twice as much light is released as would have happened with only 1 A. • ...
... • The four dNTPs are added one at a time, with apyrase degradation and washing in between. • The amount of light released is proportional to the number of bases added. Thus, if the sequence has 2 A’s in a row, both get added and twice as much light is released as would have happened with only 1 A. • ...
Mendelian Inheritance
... mild mental retardation, hyperphagia leading to obesity, short stature, and dysmorphic features (21). It is now known that the Prader-Willi syndrome is caused by any mechanism that leads to the loss of the paternal contribution of a gene(s) in the chromosome region of 15ql 1—13. A completely differe ...
... mild mental retardation, hyperphagia leading to obesity, short stature, and dysmorphic features (21). It is now known that the Prader-Willi syndrome is caused by any mechanism that leads to the loss of the paternal contribution of a gene(s) in the chromosome region of 15ql 1—13. A completely differe ...
Mastering Biology Genetics Retake
... II. Mendel and Genetics A. Answer the following genetics problems by working the Punnett squares. Then write your answers in the spaces provided. 1. In humans, the gene for normal skin pigmentation (A) is dominant to the gene for albinism (a). An albino father and a mother who has normal skin pigmen ...
... II. Mendel and Genetics A. Answer the following genetics problems by working the Punnett squares. Then write your answers in the spaces provided. 1. In humans, the gene for normal skin pigmentation (A) is dominant to the gene for albinism (a). An albino father and a mother who has normal skin pigmen ...
Peter Pristas BNK1
... • Enhancers are usually found upstream, but they can be present in introns or downstream of a gene • Enhancers act in either orientation without affecting the direction of transcription • Enhancers are usually complex, e.g. they are composed of multiple protein binding sites • Average length of an e ...
... • Enhancers are usually found upstream, but they can be present in introns or downstream of a gene • Enhancers act in either orientation without affecting the direction of transcription • Enhancers are usually complex, e.g. they are composed of multiple protein binding sites • Average length of an e ...
Unit 2: Reproduction o Recognize that the nucleus of a cell contains
... development of technologies (111-1) The Wild, Weird, Wonderful feature “Glowing Genes” provides an interesting example of such technological developments in the field of medicine. ...
... development of technologies (111-1) The Wild, Weird, Wonderful feature “Glowing Genes” provides an interesting example of such technological developments in the field of medicine. ...
Genetics Websites - Where Tomorrow Begins
... 25. What happens when a single-celled organism divides? 26. What happens when most manycelled organisms reproduce? 27. What is the difference between recessive and dominant genes? 28. Who experimented with fruit flies to learn about chromosomes? 29. Who suggested that DNA molecules were twisted like ...
... 25. What happens when a single-celled organism divides? 26. What happens when most manycelled organisms reproduce? 27. What is the difference between recessive and dominant genes? 28. Who experimented with fruit flies to learn about chromosomes? 29. Who suggested that DNA molecules were twisted like ...
Where are we heading? Unit 3:
... This lesson explains how genomic DNA is organized, and how that organization can dynamically regulate gene expression to impact cell behavior. What is in our DNA sequence? We have learned in other modules, as well as in Unit 2, how the activity of the proteins a cell synthesizes determines that cell ...
... This lesson explains how genomic DNA is organized, and how that organization can dynamically regulate gene expression to impact cell behavior. What is in our DNA sequence? We have learned in other modules, as well as in Unit 2, how the activity of the proteins a cell synthesizes determines that cell ...
Relative Expression of a Dominant Mutated ABCC8
... members. The methylation patterns of the ABCC8 promoter region and the KCNQ1 ICR (50%) were normal, regardless of the patient’s mutation or disease status (Fig. 3D and E) (some data not shown). DISCUSSION ...
... members. The methylation patterns of the ABCC8 promoter region and the KCNQ1 ICR (50%) were normal, regardless of the patient’s mutation or disease status (Fig. 3D and E) (some data not shown). DISCUSSION ...
Course Review
... why there would not be any discontinuous replication occurring in the test tube. 10. DNA is the hereditary material of all life. Comment. 11. For each pair of mutations, identify which type would be the least harmful to an organism and explain why: (a) substitution versus deletion (b) inversion vers ...
... why there would not be any discontinuous replication occurring in the test tube. 10. DNA is the hereditary material of all life. Comment. 11. For each pair of mutations, identify which type would be the least harmful to an organism and explain why: (a) substitution versus deletion (b) inversion vers ...
Point mutation
A point mutation, or single base modification, is a type of mutation that causes a single nucleotide base change, insertion, or deletion of the genetic material, DNA or RNA. The term frameshift mutation indicates the addition or deletion of a base pair. A point mutant is an individual that is affected by a point mutation.Repeat induced point mutations are recurring point mutations, discussed below.