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Positively selected sites on the surface glycoprotein (G) of infectious
Positively selected sites on the surface glycoprotein (G) of infectious

... agreement with those of others. Huang et al. (1996) reported that changes at aa 78, 81, 230–231, 272–273 and 275–276 (Fig. 3e) of IHNV enabled mutants to escape neutralizing monoclonal antibodies. In another study, Troyer et al. (2000) reported observing non-synonymous mutations at IHNV aa 252, 256, ...
RNA polymerase II is the key enzyme in the process of transcription
RNA polymerase II is the key enzyme in the process of transcription

... All questions are given in English, but you may choose yourself in which language (Norwegian or English) you prefer to answer. This exam consists of two parts. The first part is a set of questions, where you are supposed to provide brief and concise answers through a few phrases only (less than 10 p ...
Computational Pharmacology
Computational Pharmacology

... The native state of globular protein is only 20-60 kJ mol-1 (5-15kcal/mol) more stable than the denatured state. This is the equivalent of one or two water-water hydrogen bonds. It is unclear why this is the case, because the stability of proteins can be increased by adding stabilizing contacts. The ...
Ch. 4-5 - Carbon and Organic Chem
Ch. 4-5 - Carbon and Organic Chem

Variations to Mendel`s Laws
Variations to Mendel`s Laws

... There are hundreds of possible alleles Allelic combinations give rise to different phenotypes ...
1. Nucleic Acids and Chromosomes
1. Nucleic Acids and Chromosomes

... DNA: Double-stranded polynucleotide formed from two separate chains of covalently linked deoxyribonucleotide units. It serves as the cell’s store of genetic information that is transmitted from generation to generation  Doxyribose and phosphate backbone  Adenine, guanine, cytosine and thymine base ...
DISCOVERING DNA Biology Practical—DNA extraction
DISCOVERING DNA Biology Practical—DNA extraction

... The human genome consists of around 6 billion base pairs. Of this vast amount of information, only around 2% of genes code for proteins, with the rest of the genome being noncoding RNA, regulatory sequences, introns and ‘junk’ DNA. Some of these noncoding sequences may have as yet undiscovered funct ...
SBI3U 5.1 5.2 Quiz Review
SBI3U 5.1 5.2 Quiz Review

... the chromosome number from diploid to haploid is known as crossing over. • False- Reduction Division ...
Lecture Notes
Lecture Notes

... Arg, His, Ile, Leu, Lys, Met, Phe, Thr, Trp, Val Must obtain from the diet All in diary products 1 or more missing in grains and vegetables ...
Principles of Heredity
Principles of Heredity

... • Environmental Factors can also have an effect on how you look – Diet – Exercise – Smoking/Drinking – Sun exposure ...
Genetics advances and learning disability
Genetics advances and learning disability

... known for over a hundred years, and is mainly due to X-linked disorders. The X chromosome is also the best-studied human chromosome, with detailed genetic maps available. It is unsurprising then that a series of conditions associated with learning disability has been regionally mapped to the X chrom ...
Proximal promoter
Proximal promoter

... the distal sequence upstream of the gene that may contain additional regulatory elements, often with a weaker influence than the proximal promoter – Anything further upstream (but not an enhancer or other regulatory region whose influence is positional/orientation independent) – Specific transcripti ...
Developing a cure for Black Bone Disease
Developing a cure for Black Bone Disease

... Current research into enzyme therapy •Working with Protein Technologies •Dr Farid Khan from the University of Manchester •Has been tested in the animal model ...
Synthesis of Fats, Proteins, and Carbohydrates Lab
Synthesis of Fats, Proteins, and Carbohydrates Lab

... fatty acid pieces) b. Cut out all the pieces of a fat c. Construct a fatty acid and glue it onto a piece of construction paper (look in the book if you need help figuring out how to put it together) d. When a fat is made, 3 water molecules are also made (this is called a condensation reaction). Make ...
Chapter 11: Enzyme Catalysis
Chapter 11: Enzyme Catalysis

... A) All enzymes are highly specific for the reactions they catalyze. B) Prosthetic groups are loosely associated with the polypeptide chain of an enzyme. C) Activation of zymogens, such as proelastase, requires an oxidation-reduction reaction at a particular amino acid side chain. D) If an enzyme-cat ...
Chem 465 Biochemistry II Hour Exam 2
Chem 465 Biochemistry II Hour Exam 2

... I can think of at least two ways to make + supercoiled DNA. This is the simple way - Positively supercoiled DNA has more turns in it than it should. One way you can achieve this is to place the DNA in a solution with a high ionic strength. This would interfere with the negative repulsion between the ...
Lec 01 - History of Microbiology True or False 1. Robert Koch is the
Lec 01 - History of Microbiology True or False 1. Robert Koch is the

... 1.Besides providing strong evidence toward the disproof of spontaneous generation, Louis Pasteur made many other contributions toward the advancement of microbiology. Which of the following is not one of Pasteur’s contributions? (a) Provided evidence for the germ theory with his association of speci ...
Felis domesticus papillomavirus, isolated from a skin lesion, is
Felis domesticus papillomavirus, isolated from a skin lesion, is

... by amino acid and nucleotide sequence homology and contains the novel NCR-2 region. PVs are considered highly speciesspecific and are not thought to cross the species barrier ; however, there are exceptions in the veterinary literature (Perrott et al., 2000 ; Sundberg & OhBanion, 1989). Nevertheless ...
are PROTEINS!!!!!!
are PROTEINS!!!!!!

... Enzymes can only bind to certain substrates this is known as the Lock-and-Key Mechanism. When the reaction is over the Enzyme is left as it was. ...
Identification of a mutation in LARS as a novel cause of infantile
Identification of a mutation in LARS as a novel cause of infantile

... analysis. We identified two candidate loci; a major peak on chromosome 5 (141,640,648–149,027,979) and a minor peak on chromosome 15 (40,862,494–42,243,939) containing 62 and 40 genes respectively (Fig. 2a). To identify the underlying causative mutation, DNA from four individuals, three affected and ...
Intraspecific gene genealogies: trees grafting into networks
Intraspecific gene genealogies: trees grafting into networks

... Coalescent event – the time inverse of a DNA replication event; that is, the event leading to the common ancestor of two sequences looking back in time Haplotype space – the collection of points representing the possible different haplotypes. The dimension of this space is the number of characters ( ...
Promoter Regions
Promoter Regions

... base pairs before the transcription start site) Transcription Start Site: The beginning of RNA transcription. Downstream of binding sequences. Activator: A protein that binds DNA and stabilizes the binding of transcription factors. Activator Site: The region of DNA an activator binds to. Repressor: ...
module 1: introduction to the genome browser: what is a gene?
module 1: introduction to the genome browser: what is a gene?

... protein-coding genes provide the cell with the information to make messenger RNAs (mRNA), which are then used to make proteins. In this module, we will use a web-based visualization tool called a Genome Browser to explore the structure of a eukaryotic gene, and obtain a basic understanding of how th ...
Protein mteabolism L..
Protein mteabolism L..

... Non essential amino acid: Synthesized from either glycine or 3phosphoglycerate Synthesis of serine from 3-phosphoglycerate Serine is generated in a two-step reaction from 3-phosphoglycerate. The first step is an oxidation, the second a transamination. ...
D-loop - BioMed Central
D-loop - BioMed Central

... strand bias [1], is also found in nematodes, flatworms, lancelets, several crustaceans, insects, and arachnids, including Dermatophagoides pteronyssinus [1]. In contrast, negative GC-skew and positive AT-skew is common for vertebrates and echinoderms, except from Florometra [1-5]. In vertebrates, st ...
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Point mutation



A point mutation, or single base modification, is a type of mutation that causes a single nucleotide base change, insertion, or deletion of the genetic material, DNA or RNA. The term frameshift mutation indicates the addition or deletion of a base pair. A point mutant is an individual that is affected by a point mutation.Repeat induced point mutations are recurring point mutations, discussed below.
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