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Nervous System
Nervous System

... The Nervous System (Central) The nervous system is made up of the: • Brain (controls most functions of the body) • Spinal Cord (a thick column of nerve tissue that links the brain to most of the nerves in the periphal nervous system) • Network of Nerves that ...
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vollllllkkks_1

... may be synthesized and released as a neurotransmitter by the NANC neurons after their excitation by either electrical or chemical stimulation. In this regard we have suggested that NO is highly labile; therefore, it cannot be stored as a preformed neurotransmitter. There are at least three distinct ...
What`s Changing on the Prescription Drug List?
What`s Changing on the Prescription Drug List?

... What’s Changing on the Prescription Drug List? Preferred, Limited and CoverKids Formularies Every year BlueCross BlueShield of Tennessee reviews the Prescription Drug List (PDL) to determine changes based on a drug’s effectiveness, safety, and affordability. While many changes to the PDL occur at th ...
Sleep Pharmacology
Sleep Pharmacology

... • Secreted by the pineal gland, acting on the SCN • Secretion is inhibited by light • Promotes sleep initiation • Half life of 40 minutes • Hypnotic (MT1): when given one hour prior to sleep onset (3(3-10 mg dose) • Phase advancing (MT2): when given 5.55.5-6 hours prior to sleep onset (0.5(0.5-1 mg ...
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1 Short tile: Application of SECARS microscopy on the ALS model
1 Short tile: Application of SECARS microscopy on the ALS model

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Feature Competition in a Spike-Based Winner-Take
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... The administration of Alcohol with antidotes/detoxifiers (disulfiram) prescribed for 6 patients, accounts 1.18 % of drug interactions and causes flushing & facial puffiness, tachycardia, bradycardia, giddiness and hypotension . The combination of antipsychotics /anticonvulsants with anxiolytics /ant ...
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Field-theoretic approach to fluctuation effects in neural networks
Field-theoretic approach to fluctuation effects in neural networks

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Interneuron Diversity series: Circuit complexity and axon wiring

... reminiscent of ‘small-world’ or scale-free networks observed in other complex systems. The wiring-economy-based classification of cortical inhibitory interneurons is supported by the distinct physiological patterns of class members in the intact brain. The complex wiring of diverse interneuron class ...
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Me-too drugs: is there a problem
Me-too drugs: is there a problem

... incentives for innovation. This seems improbable, since me-too drugs offer relatively little therapeutic benefit over pioneering drugs. This is, however, ultimately an empirical question. One perspective on this question is the following: if consumers highly value me-too drugs over pioneers, they s ...
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Effect of deep brain stimulation on substantia nigra neurons in a

... Background Parkinson's disease (PD) is a common neurodegenerative disease, which occurs mainly in the elderly. Recent studies have demonstrated that apoptosis plays an important role in the occurrence and development of PD. Subthalamic nucleus deep brain stimulation (STN-DBS) has been recognized as ...
Can pluripotent stem cells deliver?
Can pluripotent stem cells deliver?

... motor neuron death, and which cells contribute in different forms of ALS. One key and possibly false assumption that drives current efforts is that all forms of ALS will exhibit the type of cellular nonautonomy found in animal models of SOD1mediated ALS. Thus, models of sporadic ALS and hereditary f ...
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Neuropsychopharmacology

Neuropsychopharmacology, an interdisciplinary science related to psychopharmacology (how drugs affect the mind) and fundamental neuroscience, is the study of the neural mechanisms that drugs act upon to influence behavior. It entails research of mechanisms of neuropathology, pharmacodynamics (drug action), psychiatric illness, and states of consciousness. These studies are instigated at the detailed level involving neurotransmission/receptor activity, bio-chemical processes, and neural circuitry. Neuropsychopharmacology supersedes psychopharmacology in the areas of ""how"" and ""why"", and additionally addresses other issues of brain function. Accordingly, the clinical aspect of the field includes psychiatric (psychoactive) as well as neurologic (non-psychoactive) pharmacology-based treatments.Developments in neuropsychopharmacology may directly impact the studies of anxiety disorders, affective disorders, psychotic disorders, degenerative disorders, eating behavior, and sleep behavior.The way fundamental processes of the brain are being discovered is creating a field on par with other “hard sciences” such as chemistry, biology, and physics, so that eventually it may be possible to repair mental illness with ultimate precision. An analogy can be drawn between the brain and an electronic device: neuropsychopharmacology is tantamount to revealing not only the schematic diagram, but the individual components, and every principle of their operation. The bank of amassed detail and complexity involved is huge; mere samples of some of the details are given in this article.
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