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June 20_Neurodevelopment
June 20_Neurodevelopment

... A concentration gradient of FGF and Retinoic acid help direct the development of these subdivisions. This gradient affect the expression of homeobox (Hox) transcription factors, and the process is known as rostrocaudal patterning. Changes in even one Hox transcription factor can have devastating res ...
Action Potential Webquest
Action Potential Webquest

... 5. How does an action potential conduct along an axon? 6. Describe and draw an action potential. ...
Brain Development After 18 years Old-2012
Brain Development After 18 years Old-2012

...  There was little you could do to improve damaged/injured neurons and there was minimal increases in neurons after 16 years old  Brain is Hardwired and Fixed ...
Animal Response to Stimuli
Animal Response to Stimuli

... (internal or external) which causes a cell or organism to respond. The stimulus must be of a certain minimum size before an impulse is generated - threshold level - obeys the 'all or nothing law' - domino effect. The strength of the impulse is maintained along 20 the length of the axon. ...
The future of pharmacological treatment. Anne Lingford-Hughes Professor of Addiction Biology, Imperial College.
The future of pharmacological treatment. Anne Lingford-Hughes Professor of Addiction Biology, Imperial College.

... – Mu opiate antagonist but is also some evidence that it is a partial agonist at kappa receptor • Kappa agonists are psychomimetic • Stimulating kappa receptor can reduce cocaine consumption in preclinical models. ...
Bertha K. Madras, PhD
Bertha K. Madras, PhD

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7-Sedative Hypnotic
7-Sedative Hypnotic

... share very similar properties but BZs have a much safer pharmacological profile ...
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... Then combines these signals in the cell body And then transmits an electrical impulse down its axon ...
Chapter 27
Chapter 27

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chapter48
chapter48

... K+ leak out more rapidly than Na+ can leak into the cell. The membrane is about 100 times more permeable to K+ than to Na+. Na+ pumped out of the neuron cannot easily pass back into the cell but the potassium ions pumped into the neuron can diffuse out. The flow of K+ ions in and out of the cell and ...
N receptors
N receptors

... JH, a 63-year-old architect, complains of urinary symptoms to his family physician. He has hypertension and the last 8 years, he has been adequately managed with a thiazide diuretic and an angiotensin-converting enzyme inhibitor. During the same period, JH developed the signs of benign prostatic hyp ...
Geriatric Giants, Day 1 - Acute Care Geriatric Nurse Network
Geriatric Giants, Day 1 - Acute Care Geriatric Nurse Network

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Neurology of Attachment: Wiring for Self-Care & Empathy
Neurology of Attachment: Wiring for Self-Care & Empathy

... danger…a very similar neural signature characterizes quite a few anxiety disorders.” – Distinct activation patterns in the anterior insula and right amygdala, parts of the brain involved in processing threat and pain. Similar patterns have been measured in ...
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Name in Chinese:劉福清 Name in English:Fu

... studying the neurobiological basis of speech and language. We are also approaching the neurobiological basis of schizophrenia, a complex neurodevelopmental disorder, based on our study of NRG/ErbB4 signaling in GABAergic interneurons of the forebrain. It is hoped that by identifying and characterizi ...
The Nervous System
The Nervous System

... • The forebrain has many activities that it is responsible for and is divided into many component parts. • The Hypothalamus - A section of the brain found next to the thalamus that is involved in many regulatory functions such as osmoregulation and thermoregulation. The hypothalamus has a degree of ...
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PowerPoint from lab

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Click here for handout

... Although the last 30 years extraordinary progress have been marked in efforts to deal with the interactions of opioid abuse and HIV-1/AIDS, we still lack fundamental knowledge of the cause of addiction, and certainly lack definitive treatments and cures for many patients. ...
Unit A: Nervous and Endocrine Systems
Unit A: Nervous and Endocrine Systems

... • Synapse: Space between an end plate & dendrite which acts as a connection between two neurons or a neuron and an effector (muscle, gland, etc.) • Action Potential travels to the axon terminal but cannot jump across the synaptic cleft to the next neuron or effector. • The message is passed by the A ...
DOWN - Ubiquitous Computing Lab
DOWN - Ubiquitous Computing Lab

... thought of as an analog-delay convertor. It acts somewhat like a capacitance which is progressively charged by an input until it reaches a threshold, at which point it generates an output pulse – the action potential or spike. Such neurons will naturally fire earliest when the input is strong, and w ...
Metabolism - Wayne State University
Metabolism - Wayne State University

... amnesia and suppression of reflexes) anti convulsant (marked sedation) muscle relaxation medullary depression (respiratory arrest, hypotension, CV collapse) coma. (anticonvulsants that do not cause sedation – phenobartitol and clonazepam) Lipid soluble, and distribute to the brain after absorpti ...
Ch.10
Ch.10

... inside the cell. • There is a higher concentration of Na+ outside the membrane and higher K+ concentration inside. The Na+/ K+ pumps, three sodium ions out for every two potassium ions it pumps in. • When voltage-gated channels open and close the concentration of ions change, causing a change in mem ...
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Chapter 1

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Opioid-Induced Nausea
Opioid-Induced Nausea

... may be helpful for patients who note increased nausea from motion.  • Adjust the opioid dose. If good pain relief is achieved but associated with nausea, it may be  possible to lower the dose, still retain good analgesia, but eliminate the nausea. Most patients  develop rapid tolerance to the emetic ...
Drugs for Depressive Disorders
Drugs for Depressive Disorders

... Non pharmacological therapies of depression (like electroconvulsive therapy and REM sleep deprivation) cause a similar down-regulation of postsynaptic CNS receptors. ...
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Neuropsychopharmacology

Neuropsychopharmacology, an interdisciplinary science related to psychopharmacology (how drugs affect the mind) and fundamental neuroscience, is the study of the neural mechanisms that drugs act upon to influence behavior. It entails research of mechanisms of neuropathology, pharmacodynamics (drug action), psychiatric illness, and states of consciousness. These studies are instigated at the detailed level involving neurotransmission/receptor activity, bio-chemical processes, and neural circuitry. Neuropsychopharmacology supersedes psychopharmacology in the areas of ""how"" and ""why"", and additionally addresses other issues of brain function. Accordingly, the clinical aspect of the field includes psychiatric (psychoactive) as well as neurologic (non-psychoactive) pharmacology-based treatments.Developments in neuropsychopharmacology may directly impact the studies of anxiety disorders, affective disorders, psychotic disorders, degenerative disorders, eating behavior, and sleep behavior.The way fundamental processes of the brain are being discovered is creating a field on par with other “hard sciences” such as chemistry, biology, and physics, so that eventually it may be possible to repair mental illness with ultimate precision. An analogy can be drawn between the brain and an electronic device: neuropsychopharmacology is tantamount to revealing not only the schematic diagram, but the individual components, and every principle of their operation. The bank of amassed detail and complexity involved is huge; mere samples of some of the details are given in this article.
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