OMB No. 0925-0001/0002 (Rev. 08/12), Biographical Sketch Format
... 1. Pioneering development of versatile, practical cell-free protein synthesis technology. Primarily started after I came to Stanford in 1998, the program focused on developing a complete technology package for the industrial production of pharmaceutical proteins. The major advance was gaining contro ...
... 1. Pioneering development of versatile, practical cell-free protein synthesis technology. Primarily started after I came to Stanford in 1998, the program focused on developing a complete technology package for the industrial production of pharmaceutical proteins. The major advance was gaining contro ...
Diapositive 1 - LBGI Bioinformatique et Génomique Intégratives
... Actin Related Proteins (ARPs) are key players in major biological processes important for cell life. In cytoskeleton activities, the ARP2/3 complex is essential for actin dynamics, ARP1 and ARP11 are involved in microtubule based vesicle trafficking, in nuclear functions (transcriptional activation, ...
... Actin Related Proteins (ARPs) are key players in major biological processes important for cell life. In cytoskeleton activities, the ARP2/3 complex is essential for actin dynamics, ARP1 and ARP11 are involved in microtubule based vesicle trafficking, in nuclear functions (transcriptional activation, ...
Structure–function relationships of the variable - IMGT
... (V–J-REGION) results from the rearrangement of a IGKV gene and a IGKJ gene. The VH (V–D–J-REGION) results from the rearrangement of a IGHV gene, a IGHD gene and a IGHJ gene. N1 and N2 indicate N-REGIONs not encoded in the germline genes and which result from the N-diversity mechanism at the V–D–J ju ...
... (V–J-REGION) results from the rearrangement of a IGKV gene and a IGKJ gene. The VH (V–D–J-REGION) results from the rearrangement of a IGHV gene, a IGHD gene and a IGHJ gene. N1 and N2 indicate N-REGIONs not encoded in the germline genes and which result from the N-diversity mechanism at the V–D–J ju ...
Colicins produced by the Escherichia fergusonii strains closely
... EF3) was isolated after insertion of Tn7 into the plasmid backbone, resulting in the colicinogenic plasmid DS300. The colicin E1 cea gene encoded by this plasmid had a one-nucleotide replacement (G211A) when compared to cea of pColE1-EF43, resulting in a one-amino acid change (A71T) in colicin E1 pr ...
... EF3) was isolated after insertion of Tn7 into the plasmid backbone, resulting in the colicinogenic plasmid DS300. The colicin E1 cea gene encoded by this plasmid had a one-nucleotide replacement (G211A) when compared to cea of pColE1-EF43, resulting in a one-amino acid change (A71T) in colicin E1 pr ...
Attentional Processing in Bistable Perception is Influenced by Genetic Effects
... In an effort to increase power and more robustly associate familial sinistrality effects with putative genetic effects, a standard multifactorial threshold model was used to estimate genetic load for left handedness in individual subjects. This model treats the phenotype as function of multiple gene ...
... In an effort to increase power and more robustly associate familial sinistrality effects with putative genetic effects, a standard multifactorial threshold model was used to estimate genetic load for left handedness in individual subjects. This model treats the phenotype as function of multiple gene ...
Compound specific amino acid δ13C patterns in a deep
... investigated in as much detail. Research to date suggests that δ13C-AA patterns show promise as a tracer for specific C and protein sources within food webs (e.g., Fantle et al., 1999; McMahon et al., 2011a; Larsen et al., 2012; Larsen, 2013). However, in paleoceanographic applications, δ13C-AA may a ...
... investigated in as much detail. Research to date suggests that δ13C-AA patterns show promise as a tracer for specific C and protein sources within food webs (e.g., Fantle et al., 1999; McMahon et al., 2011a; Larsen et al., 2012; Larsen, 2013). However, in paleoceanographic applications, δ13C-AA may a ...
Molecular epidemiology of infectious bursal disease virus in Zambia
... ribonucleic acid (RNA)-dependent RNA polymerase. The hypervariable region (HVR) within VP2, between amino acid residues 206 and 350, is highly conserved, with the highest amino acid sequence variation amongst serotype 1 strains. The nucleotide and deduced amino acid sequences of this region are wide ...
... ribonucleic acid (RNA)-dependent RNA polymerase. The hypervariable region (HVR) within VP2, between amino acid residues 206 and 350, is highly conserved, with the highest amino acid sequence variation amongst serotype 1 strains. The nucleotide and deduced amino acid sequences of this region are wide ...
Unusual dehydrations in anaerobic bacteria
... Gram-negative organisms A. fermentans belonging to the Sporomusa group ([40]; B. Both, personal communication) and Fusobacterium nucleaturn belonging to the Bacteroides group [41]. In a first attempt to elucidate the mechanism of the dehydration of (R)-2-hydrozyglutarate to (E)-glutaconate the stere ...
... Gram-negative organisms A. fermentans belonging to the Sporomusa group ([40]; B. Both, personal communication) and Fusobacterium nucleaturn belonging to the Bacteroides group [41]. In a first attempt to elucidate the mechanism of the dehydration of (R)-2-hydrozyglutarate to (E)-glutaconate the stere ...
Tyrosinase mutations associated with Siamese and Burmese
... A comparison of the sequence from the seven cats revealed three polymorphisms. An exon 1 G > T transversion was identified at position 715 that results in a glycine to tryptophan amino acid change (G227W). An exon 2 G > A transition was identified at position 940 that causes a glycine to arginine am ...
... A comparison of the sequence from the seven cats revealed three polymorphisms. An exon 1 G > T transversion was identified at position 715 that results in a glycine to tryptophan amino acid change (G227W). An exon 2 G > A transition was identified at position 940 that causes a glycine to arginine am ...
Structure and biosynthesis of the signal
... The signal-sequence receptor (SSR) has previously been shown to be a component of the environment which nascent polypeptides meet on passage through the endoplasmic reticulum (ER) membrane. We report here on the primary structure of the SSR as deduced from cDNA clones and from direct protein sequenc ...
... The signal-sequence receptor (SSR) has previously been shown to be a component of the environment which nascent polypeptides meet on passage through the endoplasmic reticulum (ER) membrane. We report here on the primary structure of the SSR as deduced from cDNA clones and from direct protein sequenc ...
Datasheet for T4 RNA Ligase 1 (ssRNA Ligase), High Concentration
... RECOMBINANT Store at –20°C Exp: 6/16 Description: T4 RNA Ligase 1 catalyzes the ligation of a 5´ phosphoryl-terminated nucleic acid donor to a 3´ hydroxyl-terminated nucleic acceptor through the formation of a 3´ → 5´ phosphodiester bond, with hydrolysis of ATP to AMP and PPi. Substrates include si ...
... RECOMBINANT Store at –20°C Exp: 6/16 Description: T4 RNA Ligase 1 catalyzes the ligation of a 5´ phosphoryl-terminated nucleic acid donor to a 3´ hydroxyl-terminated nucleic acceptor through the formation of a 3´ → 5´ phosphodiester bond, with hydrolysis of ATP to AMP and PPi. Substrates include si ...
64$ CfE Higher Biology Unit 1: DNA and the
... thymine always occur together, and similarly that cytosine and guanine pair up - this is called base pairing; secondly, that DNA sequences vary between species. In the early 1950s, work by Maurice Wilkins and Rosalind Franklin uncovered some characteristic features of the DNA molecule. Using a metho ...
... thymine always occur together, and similarly that cytosine and guanine pair up - this is called base pairing; secondly, that DNA sequences vary between species. In the early 1950s, work by Maurice Wilkins and Rosalind Franklin uncovered some characteristic features of the DNA molecule. Using a metho ...
Genetic assimilation can occur in the absence of selection for the
... the most frequent phenotype in the population was determined and was labelled Sold for the remainder of the simulation. An additional 500 generations of selec^ ¼ Sold followed, still tion for the particular phenotype S at low noise. This resulted in a genetically diverse population, canalized around ...
... the most frequent phenotype in the population was determined and was labelled Sold for the remainder of the simulation. An additional 500 generations of selec^ ¼ Sold followed, still tion for the particular phenotype S at low noise. This resulted in a genetically diverse population, canalized around ...
rna, meet small molecules
... “I think people just haven’t looked very hard because of the view that the structure of RNA is very different than the structure of proteins,” said Gilman. Compared with proteins, RNA has a highly dynamic and poorly defined structure at the tertiary level. But while others view the dynamic structure ...
... “I think people just haven’t looked very hard because of the view that the structure of RNA is very different than the structure of proteins,” said Gilman. Compared with proteins, RNA has a highly dynamic and poorly defined structure at the tertiary level. But while others view the dynamic structure ...
Nutritional Aspects of Inborn Errors of Metabolism
... Inherited metabolic disorders in volve différent nutritional aspects. On the one hand, the disease itself can impair normal nutrition. During the end of the fetal growth period and the first two years of life, the human brain grows at an impressive rate. This brain growth spurt period (1) is associa ...
... Inherited metabolic disorders in volve différent nutritional aspects. On the one hand, the disease itself can impair normal nutrition. During the end of the fetal growth period and the first two years of life, the human brain grows at an impressive rate. This brain growth spurt period (1) is associa ...
64$ CfE Higher Biology Unit 1: DNA and the
... thymine always occur together, and similarly that cytosine and guanine pair up - this is called base pairing; secondly, that DNA sequences vary between species. In the early 1950s, work by Maurice Wilkins and Rosalind Franklin uncovered some characteristic features of the DNA molecule. Using a metho ...
... thymine always occur together, and similarly that cytosine and guanine pair up - this is called base pairing; secondly, that DNA sequences vary between species. In the early 1950s, work by Maurice Wilkins and Rosalind Franklin uncovered some characteristic features of the DNA molecule. Using a metho ...
Document
... • multiple genetic markers available, both selection and counterselection possible • genetic crosses possible • gene knockout by homologous recombination very efficient – complete set of 4 x 6000 knockout mutants available ...
... • multiple genetic markers available, both selection and counterselection possible • genetic crosses possible • gene knockout by homologous recombination very efficient – complete set of 4 x 6000 knockout mutants available ...
Section 5.3: Proteins
... Section 5.3: Proteins Due to recent research, numerous multifunction proteins have been identified Proteins are categorized into families based on sequence and three-dimensional shape Superfamilies are more distantly related proteins (e.g., hemoglobin and myoglobin to neuroglobin) Proteins are ...
... Section 5.3: Proteins Due to recent research, numerous multifunction proteins have been identified Proteins are categorized into families based on sequence and three-dimensional shape Superfamilies are more distantly related proteins (e.g., hemoglobin and myoglobin to neuroglobin) Proteins are ...
UK and EU Implementation of the Nagoya Protocol
... led to nothing of value, this assertion (while often true) likely to lead to suspicion ...
... led to nothing of value, this assertion (while often true) likely to lead to suspicion ...
CfE Higher Biology Unit 1: DNA and the Genome
... thymine always occur together, and similarly that cytosine and guanine pair up - this is called base pairing; secondly, that DNA sequences vary between species. In the early 1950s, work by Maurice Wilkins and Rosalind Franklin uncovered some characteristic features of the DNA molecule. Using a metho ...
... thymine always occur together, and similarly that cytosine and guanine pair up - this is called base pairing; secondly, that DNA sequences vary between species. In the early 1950s, work by Maurice Wilkins and Rosalind Franklin uncovered some characteristic features of the DNA molecule. Using a metho ...
Statistical potential-based amino acid similarity
... modeling. Toward this end, recent structure prediction methods employ profile–profile alignments, and various ways of aligning two profiles have been developed. More fundamentally, a better amino acid similarity matrix can improve a profile itself; thereby resulting in more accurate profile–profile alignm ...
... modeling. Toward this end, recent structure prediction methods employ profile–profile alignments, and various ways of aligning two profiles have been developed. More fundamentally, a better amino acid similarity matrix can improve a profile itself; thereby resulting in more accurate profile–profile alignm ...
SCit: web tools for protein side chain
... function of the f and y angle values of that amino acid (3–6). Due to the number of possible combinations of the f and y values, the extension of such dependence to fragments of several residues in length is difficult (7). We have overcome this problem by describing the protein backbone conformation ...
... function of the f and y angle values of that amino acid (3–6). Due to the number of possible combinations of the f and y values, the extension of such dependence to fragments of several residues in length is difficult (7). We have overcome this problem by describing the protein backbone conformation ...
Brand, Veronica - Degenerate Primer Design using Computational Tools
... software, but also by various researchers who have used the program to look for functional genes in samples as diverse as activated sludge and engineered anaerobic bioreactors (McMahon et al. ...
... software, but also by various researchers who have used the program to look for functional genes in samples as diverse as activated sludge and engineered anaerobic bioreactors (McMahon et al. ...
Homology Modeling via Protein Threading - lmm
... is not fully understood. The primary sequence may not fully specify the tertiary structure. chaperones ...
... is not fully understood. The primary sequence may not fully specify the tertiary structure. chaperones ...
Invited Chapter One
... a single sequence and the third contains three proteins. Even though they signal for a DPP/BMP subfamily member and they are clearly R-Smads, SMA-2 and SMA-3 are different enough from other R-Smads (and each other) that they each constitute a distinct subfamily. Interestingly, the threemember nemato ...
... a single sequence and the third contains three proteins. Even though they signal for a DPP/BMP subfamily member and they are clearly R-Smads, SMA-2 and SMA-3 are different enough from other R-Smads (and each other) that they each constitute a distinct subfamily. Interestingly, the threemember nemato ...
Genetic code
The genetic code is the set of rules by which information encoded within genetic material (DNA or mRNA sequences) is translated into proteins by living cells. Biological decoding is accomplished by the ribosome, which links amino acids in an order specified by mRNA, using transfer RNA (tRNA) molecules to carry amino acids and to read the mRNA three nucleotides at a time. The genetic code is highly similar among all organisms and can be expressed in a simple table with 64 entries.The code defines how sequences of these nucleotide triplets, called codons, specify which amino acid will be added next during protein synthesis. With some exceptions, a three-nucleotide codon in a nucleic acid sequence specifies a single amino acid. Because the vast majority of genes are encoded with exactly the same code (see the RNA codon table), this particular code is often referred to as the canonical or standard genetic code, or simply the genetic code, though in fact some variant codes have evolved. For example, protein synthesis in human mitochondria relies on a genetic code that differs from the standard genetic code.While the genetic code determines the protein sequence for a given coding region, other genomic regions can influence when and where these proteins are produced.