horiuchi - Genetics
... The failure of the phoRc and phoB mutations to complement implies that there is only a single positive control gene (phoB) for AP synthesis. An alternate hypothesis that one of the mutations has a polar effect on a second cistron is unlikely. By this hypothesis, one of the mutations is a nonsense mu ...
... The failure of the phoRc and phoB mutations to complement implies that there is only a single positive control gene (phoB) for AP synthesis. An alternate hypothesis that one of the mutations has a polar effect on a second cistron is unlikely. By this hypothesis, one of the mutations is a nonsense mu ...
Inhibition by D-Glutamate of Growth and Glutamate
... of ammonia and the glutamate dehydrogenase enzyme (GDH). The glutamate then participates both directly in protein synthesis and as an intermediate in the production of many other amino acids by transamination and other reactions (Fincham, 1951a, b). The GDH enzyme is therefore of pivotal importance ...
... of ammonia and the glutamate dehydrogenase enzyme (GDH). The glutamate then participates both directly in protein synthesis and as an intermediate in the production of many other amino acids by transamination and other reactions (Fincham, 1951a, b). The GDH enzyme is therefore of pivotal importance ...
On the use of genetic divergence for identifying
... apply to both pre-mating and post-mating isolation (Gleason & Ritchie, 1998), at least in some taxa. The crucial unresolved question is whether the relationship between genetic distance and reproductive isolation is the consequence of cause-and-effect, or a product of correlation with other common g ...
... apply to both pre-mating and post-mating isolation (Gleason & Ritchie, 1998), at least in some taxa. The crucial unresolved question is whether the relationship between genetic distance and reproductive isolation is the consequence of cause-and-effect, or a product of correlation with other common g ...
Twin Studies: Revealing the Genetic Basis of
... surgical. The search for a solution would ultimately focus on delineating the responsible genes. Conversely, if components of dentofacial structure and malocclusion have trivial heritabilities, then the search needs to be directed at environmental factors including malocclusion during growth and dev ...
... surgical. The search for a solution would ultimately focus on delineating the responsible genes. Conversely, if components of dentofacial structure and malocclusion have trivial heritabilities, then the search needs to be directed at environmental factors including malocclusion during growth and dev ...
Lo, Frederick: Three Recently Developed Algorithms for Aligning Distantly Related Proteins
... log-odds probability should ideally have a value of 1 but is present to allow flexibility to improve alignment accuracy. Parameter f will be determined by using training sets. Parameter wj provides extra weight for α-helix and β-strand residues, to differentiate them from coil regions. Although Yang ...
... log-odds probability should ideally have a value of 1 but is present to allow flexibility to improve alignment accuracy. Parameter f will be determined by using training sets. Parameter wj provides extra weight for α-helix and β-strand residues, to differentiate them from coil regions. Although Yang ...
Bile
... Bile acids are derivatives of cholesterol synthesized in the hepatocyte. It has various components like water, cholesterol, bile pigments, anions of the bile acids, phospholipids, bicarbonate and other ions. Cholesterol is converted into the cholic acid and chenodeoxycholic acids, which are then con ...
... Bile acids are derivatives of cholesterol synthesized in the hepatocyte. It has various components like water, cholesterol, bile pigments, anions of the bile acids, phospholipids, bicarbonate and other ions. Cholesterol is converted into the cholic acid and chenodeoxycholic acids, which are then con ...
Isolation and Characterization of Plastidic Glucose-6-Phosphate Dehydrogenase
... reductant and precursors for a variety of biosynthetic reactions. The steps of the OPPP are outlined in Figure 1. The OPPP is divided into two main phases namely oxidative or regenerative. The oxidative phase begins with G-6-P being oxidized by glucose 6phosphate dehydrogenase (G6PDH) and 6-phosphog ...
... reductant and precursors for a variety of biosynthetic reactions. The steps of the OPPP are outlined in Figure 1. The OPPP is divided into two main phases namely oxidative or regenerative. The oxidative phase begins with G-6-P being oxidized by glucose 6phosphate dehydrogenase (G6PDH) and 6-phosphog ...
Inhibition by D-Glutamate of Growth and Glutamate
... of ammonia and the glutamate dehydrogenase enzyme (GDH). The glutamate then participates both directly in protein synthesis and as an intermediate in the production of many other amino acids by transamination and other reactions (Fincham, 1951a, b). The GDH enzyme is therefore of pivotal importance ...
... of ammonia and the glutamate dehydrogenase enzyme (GDH). The glutamate then participates both directly in protein synthesis and as an intermediate in the production of many other amino acids by transamination and other reactions (Fincham, 1951a, b). The GDH enzyme is therefore of pivotal importance ...
Bioinorganic motifs: towards functional classification of metalloproteins
... such as calmodulin are referred to as ‘cofactors’ in biochemical literature). Therefore, the use of this term should be generally avoided, apart from certain well established combinations, e.g. molybdenum cofactor and iron–molybdenum cofactor. Both the apoprotein and the prosthetic group are integra ...
... such as calmodulin are referred to as ‘cofactors’ in biochemical literature). Therefore, the use of this term should be generally avoided, apart from certain well established combinations, e.g. molybdenum cofactor and iron–molybdenum cofactor. Both the apoprotein and the prosthetic group are integra ...
Retrieving data from UniProt databases Further reading Support
... We can find out much more about the function of proteins by studying properties such as the biological processes they are involved in, their post-translational modifications, their interaction with other molecules, and their location in cells and organisms, than we could ever learn by studying the D ...
... We can find out much more about the function of proteins by studying properties such as the biological processes they are involved in, their post-translational modifications, their interaction with other molecules, and their location in cells and organisms, than we could ever learn by studying the D ...
Drosophila windpipe codes for a leucine
... protein has 677 residues with a potential signal peptide cleavage sequence located between amino acids 20 and 21 (ANA-TP). Based on hydropathy analysis, residues 451– 472 form a transmembrane domain, followed by an acidic-rich ‘stop-transfer’ sequence (KRKC). The predicted extracellular domain conta ...
... protein has 677 residues with a potential signal peptide cleavage sequence located between amino acids 20 and 21 (ANA-TP). Based on hydropathy analysis, residues 451– 472 form a transmembrane domain, followed by an acidic-rich ‘stop-transfer’ sequence (KRKC). The predicted extracellular domain conta ...
Quasispecies evolution of a hypervariable region of the feline
... passage, the quasispecies apparently evolved at both the nucleotide (Fig. 1 a) and amino acid (Figs 2 a and 3 a) levels. This was due both to loss of sequence variability, largely resulting from loss of sequence found in five clones of the 5th passage virus, and the generation of apparently novel se ...
... passage, the quasispecies apparently evolved at both the nucleotide (Fig. 1 a) and amino acid (Figs 2 a and 3 a) levels. This was due both to loss of sequence variability, largely resulting from loss of sequence found in five clones of the 5th passage virus, and the generation of apparently novel se ...
Turnip yellow mosaic virus RNA can be separated into two distinct
... attributed to accidental breakage of the infectious RNA molecule rather than taken as evidence for a specific cleavage. In this paper we shall show that moderate heat treatment in the presence of SDS or EDTA causes TYMV RNA to separate into distinct heavy and light components with molecular weights ...
... attributed to accidental breakage of the infectious RNA molecule rather than taken as evidence for a specific cleavage. In this paper we shall show that moderate heat treatment in the presence of SDS or EDTA causes TYMV RNA to separate into distinct heavy and light components with molecular weights ...
Science 11th grade LEARNING OBJECT Why are carboxylic acids
... Carboxylic acids have a carboxyl functional group in a primary carbon. The carboxylic acid found in human sweat is formic acid. The acetic acid in aqueous solution is known as aspirin. If an acid that is part of a carboxylic acid has a pKa value of 0= 1, it is a strong acid. e) The boiling point of ...
... Carboxylic acids have a carboxyl functional group in a primary carbon. The carboxylic acid found in human sweat is formic acid. The acetic acid in aqueous solution is known as aspirin. If an acid that is part of a carboxylic acid has a pKa value of 0= 1, it is a strong acid. e) The boiling point of ...
Human mitochondrial leucyl tRNA synthetase can suppress non
... was achieved for the MT-TV mutation using the non-cognate leucyl tRNA synthetase (Montanari et al, 2010). More recently it has been shown, again in yeast (Francisci et al, 2011), that not only do non-cognate aaRS have the ability to suppress the defects caused by mt-tRNA mutations, but that isolated ...
... was achieved for the MT-TV mutation using the non-cognate leucyl tRNA synthetase (Montanari et al, 2010). More recently it has been shown, again in yeast (Francisci et al, 2011), that not only do non-cognate aaRS have the ability to suppress the defects caused by mt-tRNA mutations, but that isolated ...
Proteins and Albumin
... of the essential amino acids (namely, histidine, leucine, isoleucine, lysine, phenylalanine, methionine, threonine, tryptophan, and valine2) is necessary for protein synthesis. Most calorically adequate diets provide sufficient amounts of the essential amino acids; however, malnutrition is a cause o ...
... of the essential amino acids (namely, histidine, leucine, isoleucine, lysine, phenylalanine, methionine, threonine, tryptophan, and valine2) is necessary for protein synthesis. Most calorically adequate diets provide sufficient amounts of the essential amino acids; however, malnutrition is a cause o ...
Free tyrosine and tyrosine-rich peptide
... to be a portion of neurotoxic region), and VNITIKQHTVTTTT (helix 2, threonine-rich toxic sequence). The key common feature among the Cu-binding sequences in PrPs is the presence of His-residue(s) possibly behaving as the anchors for the copper [9,10]. The neurotoxic threonine-rich region correspondi ...
... to be a portion of neurotoxic region), and VNITIKQHTVTTTT (helix 2, threonine-rich toxic sequence). The key common feature among the Cu-binding sequences in PrPs is the presence of His-residue(s) possibly behaving as the anchors for the copper [9,10]. The neurotoxic threonine-rich region correspondi ...
Influence of oxygen deficiency and the role of specific amino acids in
... the shoot apex. When apices were immersed in cryoprotectant solution, the well-oxygenated peripheral regions (foliage leaf bases) became likewise hypoxic within a few minutes, probably resulting from strongly restricted gaseous diffusion. Conclusions: Tissue level oxygen measurements supported the o ...
... the shoot apex. When apices were immersed in cryoprotectant solution, the well-oxygenated peripheral regions (foliage leaf bases) became likewise hypoxic within a few minutes, probably resulting from strongly restricted gaseous diffusion. Conclusions: Tissue level oxygen measurements supported the o ...
Candidate gene analysis of thyroid hormone receptors
... 85±95% similar comparing human to Ambystoma, and TRb shows 85±91% sequence similarity for this same comparison. Several amino acid substitutions were either observed uniquely among all ambystomatid sequences, or among metamorphic-failure salamanders in general. Three of these substitutions (TRa: Ala ...
... 85±95% similar comparing human to Ambystoma, and TRb shows 85±91% sequence similarity for this same comparison. Several amino acid substitutions were either observed uniquely among all ambystomatid sequences, or among metamorphic-failure salamanders in general. Three of these substitutions (TRa: Ala ...
Atom depth in protein structure and function
... area. Depth has been found to be correlated with several molecular, residue and atomic properties, such as average protein domain size, protein stability, free energy of formation of protein complexes, amino acid type hydrophobicity, residue conservation and hydrogen/deuterium amide proton exchange ...
... area. Depth has been found to be correlated with several molecular, residue and atomic properties, such as average protein domain size, protein stability, free energy of formation of protein complexes, amino acid type hydrophobicity, residue conservation and hydrogen/deuterium amide proton exchange ...
Isoelectric point prediction from the amino acid sequence of a protein
... phosphorylation which can alter the ...
... phosphorylation which can alter the ...
Synaptonemal complex proteins - Journal of Cell Science
... SYN1 and COR1 cDNAs Sequence analysis of the hamster cDNAs encoding Syn1a-d fusion proteins (accession number L32978; Moens et al., 1992) proved that these represent overlapping cDNAs of the hamster homologue of the rat SCP1 gene that encodes a 125 kDa SC protein (Meuwissen et al., 1992). The hamste ...
... SYN1 and COR1 cDNAs Sequence analysis of the hamster cDNAs encoding Syn1a-d fusion proteins (accession number L32978; Moens et al., 1992) proved that these represent overlapping cDNAs of the hamster homologue of the rat SCP1 gene that encodes a 125 kDa SC protein (Meuwissen et al., 1992). The hamste ...
Efficient seeding techniques for protein similarity search
... intermediate between ordinary spaced seeds and vector seeds: subset seeds allow one to distinguish between different types of mismatches (or matches) but still treat seed positions independently rather than cumulatively. Distinguishing different mismatches is not done by scoring them, but by extendi ...
... intermediate between ordinary spaced seeds and vector seeds: subset seeds allow one to distinguish between different types of mismatches (or matches) but still treat seed positions independently rather than cumulatively. Distinguishing different mismatches is not done by scoring them, but by extendi ...
Classification and Phylogenetic Analysis of the cAMP
... sition-specific iterated BLAST) (Altschul et al. 1997) set to search the nonredundant database using human RI␣ as the query sequence and a BLOSUM62 weight matrix (Henikoff and Henikoff 1992). Sequences identified in this first stage were used as query sequences for subsequent searches. Sequences une ...
... sition-specific iterated BLAST) (Altschul et al. 1997) set to search the nonredundant database using human RI␣ as the query sequence and a BLOSUM62 weight matrix (Henikoff and Henikoff 1992). Sequences identified in this first stage were used as query sequences for subsequent searches. Sequences une ...
Structural Investigation of the Antibiotic and ATP
... 30, Arg 42 to Gly 46, and Glu 60 to Ala 62 were disordered in the electron density map. These residues are clearly defined in the present model. In the original structure determination of KNTase, there were two large peaks of electron density that were symmetryrelated to one another and were positio ...
... 30, Arg 42 to Gly 46, and Glu 60 to Ala 62 were disordered in the electron density map. These residues are clearly defined in the present model. In the original structure determination of KNTase, there were two large peaks of electron density that were symmetryrelated to one another and were positio ...
Genetic code
The genetic code is the set of rules by which information encoded within genetic material (DNA or mRNA sequences) is translated into proteins by living cells. Biological decoding is accomplished by the ribosome, which links amino acids in an order specified by mRNA, using transfer RNA (tRNA) molecules to carry amino acids and to read the mRNA three nucleotides at a time. The genetic code is highly similar among all organisms and can be expressed in a simple table with 64 entries.The code defines how sequences of these nucleotide triplets, called codons, specify which amino acid will be added next during protein synthesis. With some exceptions, a three-nucleotide codon in a nucleic acid sequence specifies a single amino acid. Because the vast majority of genes are encoded with exactly the same code (see the RNA codon table), this particular code is often referred to as the canonical or standard genetic code, or simply the genetic code, though in fact some variant codes have evolved. For example, protein synthesis in human mitochondria relies on a genetic code that differs from the standard genetic code.While the genetic code determines the protein sequence for a given coding region, other genomic regions can influence when and where these proteins are produced.