Dental Microbiology #211 IMMUNOLOGY Lecture 1
... A substance capable of inducing an adaptive immune response is called an Antigen. In order to induce an immune response an antigen (Ag) must be foreign to the host. Microorganisms express a large variety of proteins carbohydrates and lipids that are foreign to the host. Red blood cells, proteins fro ...
... A substance capable of inducing an adaptive immune response is called an Antigen. In order to induce an immune response an antigen (Ag) must be foreign to the host. Microorganisms express a large variety of proteins carbohydrates and lipids that are foreign to the host. Red blood cells, proteins fro ...
eCSI Case Powerpoint
... • The majority of the gated cells are negative for CD5, and most of the gated cells are negative for CD4 and CD8. • There are small numbers of normal CD5+ CD8+ T cells (in red) and CD5+ CD4+ T cells (in green). • There are subsets of the abnormal cells positive for CD8 or CD4 only. ...
... • The majority of the gated cells are negative for CD5, and most of the gated cells are negative for CD4 and CD8. • There are small numbers of normal CD5+ CD8+ T cells (in red) and CD5+ CD4+ T cells (in green). • There are subsets of the abnormal cells positive for CD8 or CD4 only. ...
Chapter 17 Transplantation
... - If rejection is suspected a tissue biopsy is performed looking for immune cell infiltration and/or inflammation - Tx: increase immunosuppressive therapy increased risk of infection, malignancy, and drug toxicity - Type 1 cytokine production (DTH) Chronic rejection - weeks/months/years - fibrobla ...
... - If rejection is suspected a tissue biopsy is performed looking for immune cell infiltration and/or inflammation - Tx: increase immunosuppressive therapy increased risk of infection, malignancy, and drug toxicity - Type 1 cytokine production (DTH) Chronic rejection - weeks/months/years - fibrobla ...
2nd Exam 2015
... Diversity in antibody recognition comes from differences in V-region sequences in the H and L chains and the combinations of various genes coding for V-region components to produce the CDR’s. That diversity is enormously increased by “combinatorial” association. What is “combinatorial association re ...
... Diversity in antibody recognition comes from differences in V-region sequences in the H and L chains and the combinations of various genes coding for V-region components to produce the CDR’s. That diversity is enormously increased by “combinatorial” association. What is “combinatorial association re ...
SUN-206 Inhibition of MMP-9 gene expression and cancer cell
... for 72 h with 100 nM PMA (37°C/5% CO2) then fresh medium without PMA was added being the cells incubated for further 24 h. The cells were infected for 1 or 3 h for fast or slow growers, respectively. The intracellular persistence was evaluated by CFU enumeration at different time points from 1 to 24 ...
... for 72 h with 100 nM PMA (37°C/5% CO2) then fresh medium without PMA was added being the cells incubated for further 24 h. The cells were infected for 1 or 3 h for fast or slow growers, respectively. The intracellular persistence was evaluated by CFU enumeration at different time points from 1 to 24 ...
Host Defense Against Infection
... - Innate immune system is phylogenetically conserved and is present in almost all multicellular organisms. - Recently-identified Toll-like receptors recognize specific patterns of microbial components and regulates the activation of innate immunity. ...
... - Innate immune system is phylogenetically conserved and is present in almost all multicellular organisms. - Recently-identified Toll-like receptors recognize specific patterns of microbial components and regulates the activation of innate immunity. ...
Ch 14 Lymphatic System
... - hair traps pathogens - Sweat and mucus - rinses away microorganisms 3) Chemical barriers - enzymes (gastric enzymes HCl and pepsin) lethal to stomach pathogens - Lysozyme in tears kills bacteria - Salt from sweat kills skin bacteria - Interferons hormone-like peptides produced by lymphocytes and ...
... - hair traps pathogens - Sweat and mucus - rinses away microorganisms 3) Chemical barriers - enzymes (gastric enzymes HCl and pepsin) lethal to stomach pathogens - Lysozyme in tears kills bacteria - Salt from sweat kills skin bacteria - Interferons hormone-like peptides produced by lymphocytes and ...
Lesson 1: The Immune System - Lecture Notes | Vaccine Education
... defend the body against attacks by foreign organisms. Some of these organisms can cause disease and are known as pathogens. 2. The responses our bodies make against potential pathogens are known as immune responses. 3. Cells of the immune system are found in the bone marrow, lymph nodes, spleen, thy ...
... defend the body against attacks by foreign organisms. Some of these organisms can cause disease and are known as pathogens. 2. The responses our bodies make against potential pathogens are known as immune responses. 3. Cells of the immune system are found in the bone marrow, lymph nodes, spleen, thy ...
Genetics of Immunity
... against that pathogen • Protection of having a previous attack without actually having the risk • Once some diseases have been removed with vaccines there is no longer any need to administer them: ...
... against that pathogen • Protection of having a previous attack without actually having the risk • Once some diseases have been removed with vaccines there is no longer any need to administer them: ...
Genetics of Immunity
... against that pathogen • Protection of having a previous attack without actually having the risk • Once some diseases have been removed with vaccines there is no longer any need to administer them: ...
... against that pathogen • Protection of having a previous attack without actually having the risk • Once some diseases have been removed with vaccines there is no longer any need to administer them: ...
8_23_cancer
... expressed on tumor cells, but which are not unique (these same antigens may be expressed on normal cells of other tissue types, or at other stages of development) • Tumor-specific antigens are often seen in chemicallyinduced tumors, in which a mutagen has induced a change that is sufficiently large ...
... expressed on tumor cells, but which are not unique (these same antigens may be expressed on normal cells of other tissue types, or at other stages of development) • Tumor-specific antigens are often seen in chemicallyinduced tumors, in which a mutagen has induced a change that is sufficiently large ...
Procedure: Read the first three paragraphs of the Scientific
... deadly runaway response by "killer" T cells of the immune system. Two years ago investigators found the reason for that lethal overreaction. People with XLP turn out to be missing a small protein termed SAP, which consists of a single SH2 domain (related to the SH2 domains mentioned in the main arti ...
... deadly runaway response by "killer" T cells of the immune system. Two years ago investigators found the reason for that lethal overreaction. People with XLP turn out to be missing a small protein termed SAP, which consists of a single SH2 domain (related to the SH2 domains mentioned in the main arti ...
Who Gets Lupus?
... 2. C1q binds to and clears apoptotic blebs (sources of autoantigens) 3. Absence of C1q permits sustained infections that could trigger autoimmune response. ...
... 2. C1q binds to and clears apoptotic blebs (sources of autoantigens) 3. Absence of C1q permits sustained infections that could trigger autoimmune response. ...
The Specific Immune Response
... Particularly effective against pathogens such as viruses and extracellular bacteria in the blood or lymph and also against soluble pathogen products such toxins ...
... Particularly effective against pathogens such as viruses and extracellular bacteria in the blood or lymph and also against soluble pathogen products such toxins ...
The immunological principles underlying vaccine
... been no prior exposure, the organism will be phagocytosed by immature dendritic cells; the process is initiated by PAMP:PRR binding leading to changes in the cytoskeleton proteins that cause the development of the digestive phagosome [11]. Subsequently, the microbe is degraded and antigenic fragment ...
... been no prior exposure, the organism will be phagocytosed by immature dendritic cells; the process is initiated by PAMP:PRR binding leading to changes in the cytoskeleton proteins that cause the development of the digestive phagosome [11]. Subsequently, the microbe is degraded and antigenic fragment ...
Lymphatic System PowerPoint
... clone itself over and over (plasma cells) • After infection has been defeated some plasma cells will stay in the body to jump start new attack if same pathogens tries to invade again. ...
... clone itself over and over (plasma cells) • After infection has been defeated some plasma cells will stay in the body to jump start new attack if same pathogens tries to invade again. ...
The humoral immune response defends against pathogens that are
... antigen whenever it is encountered. The binding can fight infection in several ways. Antibodies can bind to viruses or bacteria, which interferes with the chemical interactions required for them to infect or bind to other cells. The antibodies may create bridges between different particles containin ...
... antigen whenever it is encountered. The binding can fight infection in several ways. Antibodies can bind to viruses or bacteria, which interferes with the chemical interactions required for them to infect or bind to other cells. The antibodies may create bridges between different particles containin ...
What`s so great about a little Cell
... The cell is the most basic unit of life, performing all of the functions necessary for life. In the eukaryotic vertebrate cell these functions are performed by various organelles within the cell. The cell membrane plays a role in the dynamic process of molecular movement in and out of the cell. At t ...
... The cell is the most basic unit of life, performing all of the functions necessary for life. In the eukaryotic vertebrate cell these functions are performed by various organelles within the cell. The cell membrane plays a role in the dynamic process of molecular movement in and out of the cell. At t ...
Cells
... peptides that can associate with class I or class II MHC molecules and then be presented on the cell surface to a T cell. Superantigens are not processed, but rather exert their effect externally by binding as an intact (non-fragmented) molecule to T cell receptor (TCR) molecule and to some portion ...
... peptides that can associate with class I or class II MHC molecules and then be presented on the cell surface to a T cell. Superantigens are not processed, but rather exert their effect externally by binding as an intact (non-fragmented) molecule to T cell receptor (TCR) molecule and to some portion ...
BS963 (Autoimmunity) 2011
... Female: Male ratio 5:1. At least partly due to modulation of the autoimmune response by oestrogens. Thyroid autoimmunity usually subsides during pregnancy, and rebounds post-partum. Stress. Bereavement, divorce, job loss may proceed onset. Neuroendocrine pathways affecting the immune system? Smoking ...
... Female: Male ratio 5:1. At least partly due to modulation of the autoimmune response by oestrogens. Thyroid autoimmunity usually subsides during pregnancy, and rebounds post-partum. Stress. Bereavement, divorce, job loss may proceed onset. Neuroendocrine pathways affecting the immune system? Smoking ...
CELLS AND TISSUES OF THE ADAPTIVE IMMUNE SYSTEM
... ingest dead host cells as part of the cleaning up process after infection or sterile tissue injury Activated macrophages secrete proteins, called cytokines, Macrophages serve as APCs promote repair of damaged tissues by stimulating new blood vessel growth (angiogenesis) and synthesis of collagen-ric ...
... ingest dead host cells as part of the cleaning up process after infection or sterile tissue injury Activated macrophages secrete proteins, called cytokines, Macrophages serve as APCs promote repair of damaged tissues by stimulating new blood vessel growth (angiogenesis) and synthesis of collagen-ric ...
T cell
T cells or T lymphocytes are a type of lymphocyte (in turn, a type of white blood cell) that plays a central role in cell-mediated immunity. They can be distinguished from other lymphocytes, such as B cells and natural killer cells (NK cells), by the presence of a T-cell receptor (TCR) on the cell surface. They are called T cells because they mature in the thymus (although some also mature in the tonsils). The several subsets of T cells each have a distinct function. The majority of human T cells rearrange their alpha/beta T cell receptors and are termed alpha beta T cells and are part of adaptive immune system. Specialized gamma delta T cells, which comprise a minority of T cells in the human body (more frequent in ruminants), have invariant TCR (with limited diversity), can effectively present antigens to other T cells and are considered to be part of the innate immune system.