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The Body`s Defenses
The Body`s Defenses

... When the body is invaded, four important nonspecific defenses take action: the inflammatory response; the temperature response; proteins that kill or inhibit pathogens; and white blood cells, which attack and kill pathogens. Inflammatory Response: Injury or local infection, such as a cut or a scrape ...
IMMUNE SYSTEM
IMMUNE SYSTEM

... products, tissues and molecules and their interactions incurred during the phylogenetic development of organisms  Arose in nearly all organisms as response to the external environment in an effort to survive  Evolution of the immune system is always co-evolution with pathogens  Diffuse organ that ...
Innate immunity
Innate immunity

... Innate immunity PartⅠ overview of innate immunity  PartⅡ innate immune cells  PartⅢ functions of innate immunity ...
The Immune System - Chicagoland Jewish High School
The Immune System - Chicagoland Jewish High School

... • 2. Act rapidly with infection • 3. Employ negative test that cannot be foiled by copycat foreign cells ...
File - PBL Group 14
File - PBL Group 14

... 2. Monocytes (differentiate into macrophages)  Largest of the leucocytes  Irregular nucleaus in abundant cytoplasm, containing few vacuoles  Monocytes migrate to the cell where they become macrophages, Kupffer cells or antigen-presenting dendritic cells  They produce a variety of cytokines when ...
1 Immunoglobulins – vitally important constituents of our blood
1 Immunoglobulins – vitally important constituents of our blood

Osmoregulation, Excretion Immune System
Osmoregulation, Excretion Immune System

... 3. Draw a picture or series of pictures that demonstrates what happens in the inflammatory response when bacteria get in through a cut in the skin. Include the following: macrophage, mast cell, neutrophil, dendritic cell, signaling molecules, histamine, toll-like receptors, pathogen, phagocytosis, v ...
Thymus
Thymus

... The site that lymphocytes generate and mature into functional cells Bone marrow or Bursa, and Thymus , Thymus , Peripheral immune organs or secondary lymphoid organs and tissues The sites that T and B lymphocytes reside in and respond to antigens spleen , lymph nodes , mucosal immune system ...
Immune System - Crestwood Local Schools
Immune System - Crestwood Local Schools

... Distinguishing Self from Nonself • The ability to recognize the difference between cells of your own body and cells from another individual seems to have evolved early in the history of life. • Sponges, thought to be the most ancient animals, attack tissues from other sponges just like insects and ...
Slide 1
Slide 1

... b. the site where the B lymphocytes (in bone marrow?) and T lymphocytes (in thymus) proliferate and differentiate into different types. 2. Peripheral lymphoid tissue: a. develops later and retains forever. b. the site where immune cells perform their functions. Makes up of peripheral lymph organs, o ...
AP2 study guide IMMUNE SYSTEM
AP2 study guide IMMUNE SYSTEM

... o Neutrophils (most common) – limited capacity to kill o Macrophages – potent phagocyte (derived from monocytes, which become macrophages within 12 hours of leaving the bloodstream!) o Mast Cells – allergic reaction – release histamines o NK Cells (natural killer cells) – able to recognize cancer ce ...
The Human Immune System PPT
The Human Immune System PPT

... circulate throughout the blood, but will enter the body’s tissues if invaders are detected ...
Diphtheria Toxin and Engineered Receptor
Diphtheria Toxin and Engineered Receptor

... Immunologists are using diphtheria toxin (DT) in studies to sort out the function of various immune cells. Diphtheria toxin is a potent inhibitor of protein synthesis and will kill about any cell to which it gains entry. Diphtheria toxin receptor (DTR), either simian or human, is genetically attache ...
The Simplified Immune Response  1.  Pathogens Invade
The Simplified Immune Response 1. Pathogens Invade

... ...
(b) activate the adaptive immune response
(b) activate the adaptive immune response

... fetal liver during fetal life. Monocytes arise from a precursor cell of the myeloid lineage in the bone marrow, circulate in the blood, and are recruited into tissues in inflammatory reactions, where they further mature into macrophages. Subsets of blood monocytes exist, which have distinct inflamma ...
Glossary of Terms
Glossary of Terms

Infectious Diseases
Infectious Diseases

... • Chemical mediators are released, blood vessels dilate and increase blood flow, this allows phagocytes to leave blood stream and enter body tissues. This continues until the pathogen is destroyed. • Symptoms – heat, redness, and swelling ...
B cell development, selection and maturation
B cell development, selection and maturation

... Multi-potent hematopoietic stem cells generate all the cells of the immune system ...
CANCER = UNCONTROLLED CELL DIVISION
CANCER = UNCONTROLLED CELL DIVISION

... and carried to other parts of the body forming a secondary tumour. Unchecked cancerous cells ultimately take over the body leading to malfunction and death. Cancers are thought to start when changes occur in the genes that control cell division. Mutated gene that causes cancer is an oncogene, a chan ...
Poster
Poster

... Refractory CD (RCD) and RCD-associated lymphoma that do not respond to a gluten-free diet, CD has become a far more complicated disease. Delving deeper in the structural and cellular mechanisms leading to inappropriate T cell response and resulting inflammation will help establish therapeutic protoc ...
BLOOD CELLS / FORMED ELEMENTS (REVIEW) 1. (red blood cells
BLOOD CELLS / FORMED ELEMENTS (REVIEW) 1. (red blood cells

... agranulocytes _________________________________ ...
Exercise 35
Exercise 35

...  Cytotoxic T Cells (CD8) a.k.a. “killer T Cells”  Attack virally or bacterial infected cells and cancerous cells directly  Memory T Cells provide for a prolonged protection against specific antigens (immunity in the true sense) ...
432W9EX1
432W9EX1

... 6. According to the clonal selection theory, all the immuoglobulin molecules on a single B cell have the same antigenic specificity. Explain why the presence of both IgM and IgD on the same B cell does not violate the unispecificity implied by clonal selection. ...
The Generation of Diversity (GOD): How to Ensure
The Generation of Diversity (GOD): How to Ensure

... in severe autoimmune disease in mice (J. Immunol. 155, 1151, 1995). The condition resembled the one described in the 1969 study. Sakaguchi called the cells regulatory T cells. • It is clear that these regulatory T cells—or Tregs—are crucial to keeping the immune system in check, although the exact m ...
Alterations in White Blood Cells
Alterations in White Blood Cells

... The cytokines that stimulate hematopoiesis are called colonystimulating factors (CSFs), based on their ability to promote the growth of the hematopoietic cell colonies from bone marrow precursors. Lineage-specific CSFs that act on committed progenitor cells ...
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Lymphopoiesis



Lymphopoiesis (lĭm'fō-poi-ē'sĭs) (or lymphocytopoiesis) is the generation of lymphocytes, one of the five types of white blood cell (WBC). It is more formally known as lymphoid hematopoiesis.Pathosis in lymphopoiesis leads to any of various lymphoproliferative disorders, such as the lymphomas and lymphoid leukemias.
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