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03.Lecture (3) Lymphoid system Hazem KSU 2008
03.Lecture (3) Lymphoid system Hazem KSU 2008

... corticomedullary junction. There, they meet and interact with a second set of epithelial reticular cells (antigen presenting cells such as dendritic cells and macrophages). Those that efficiently bind to self peptides of the pMHC I or pMHC II on these APCs are potentially autoreactive and undergo ap ...
organ limfoid
organ limfoid

... – pain caused by inflammatory chemicals and pressure on nerves ...
Lymphoid neogenesis in vascular chronic inflammation - HAL
Lymphoid neogenesis in vascular chronic inflammation - HAL

... Interestingly, TLOs are also present in the context of atherothrombosis. Indeed, TLOs were detected in the adventitia of human atherosclerotic arteries as early as the 1950s (14), a process that has been recently revisited (15-18). We could also characterize adventitial lymphoid aggregates distribut ...
(dendritic) cells
(dendritic) cells

... hands off the tumor cell information to CTLs. The CTLs then divide, circulate throughout the body, and kill any tumor cells they come in contact with. Above we covered what happens normally in the body when a cell becomes cancerous. This process occurs countless times as cells get genetic mutations ...
biopresibstandards
biopresibstandards

... is often lethal, even when antibiotic treatments are give. Anthrax spores have sometimes been used deliberately to infect more people and cause death. Monoclonal antibodies are being developed which neutralize one of the toxins and therefore sustain the patient’s life until their immune system produ ...
Immune system
Immune system

... be accessories lobules of thymus. Basic function of thymus maturation and supporting of effector cells (killer) and regulatory cells (helper and supressor) Т-lymphocytes populations. Also thymus takes part into regulation of neuro-muscular transmission, phosphoric-calcium metabolism, carbohydrate an ...
Week 1
Week 1

Vorlage Translation Forschungsprojekt 2 Arbeitsgruppe Prof. Dr
Vorlage Translation Forschungsprojekt 2 Arbeitsgruppe Prof. Dr

... this hypothesis using various kinds of cytotoxic and regulatory cell types. On the one hand, targeted transfer of Pfn-cDNA into the GzmB locus of cells, which normally produce GzmB only, but not Pfn, may convert their immunoregulatory function into a cytotoxic one. Besides regulatory T cells, certai ...
CD8 T cell
CD8 T cell

... • B cells are triggered to proliferate and differentiate to plasma cells by exposure to that specific antigen. • Triggering this proliferation also requires help by exposure to CD4+ Th2 cytokines. • Plasma cells then secrete this specific antibody. • For memory B cells, exposure to antibody alone is ...
view file - S
view file - S

... An important aim of an electrophysiological study of the PVS is to investigate its function. The expected one is a new circulatory function. The supporting evidence for circulation in primo vessels (Bonghan ducts) was obtained by observing the flow of a staining dye, Alcian blue, which was injected ...
No Slide Title
No Slide Title

... Hoovers, wood floors, ...
Document
Document

... 1. Phagocytosis is a component of innate and aquired immunity. It is the principal means of destroying pathogenic bacteria and fungi. Phagocytosis initiates the process of antigen presentation. 2. Many phagocytic receptors recognize a diverse array of microbial pathogens. Some pathogens (e.g., S. pn ...
Allergy PPT - University of Leicester
Allergy PPT - University of Leicester

... •1980’s & 1990’s Environment – ante-natal & adult, allergens, Th2 cells •1990’s & 2000’s Microbial experience, Epithelium, Tregs Although undoubtedly a useful model, the textbook ‘skew to Th2’ model is too simplistic to explain allergy Allergy is a disease of impaired immune regulation Where is the ...
Immunology - Chapter..
Immunology - Chapter..

...  Granulocyte-monocyte progenitors in the bone marrow differentiate into pro-monocytes, which enter the blood, where these differentiate into monocytes  Monocytes circulate on the blood for about 8 hours, then migrate into tissues and become tissue specific macrophages or dendritic cells ...
Innate Immunity I
Innate Immunity I

Stress and the immune system
Stress and the immune system

...  When one branch is active it produces chemicals called cytokines that block the action of the other branch.  This ensures that the body has a balance between the two types of immune response with Th2 active during the day and Th1 active during the night.  Stress can influence the balance between ...
Acquired Immunity
Acquired Immunity

... * The acquired immune response is more specialized than innate immune response * The acquired immune response involves a combination of two mechanisms : 1) Humoral immune response 2) cell mediated immune response * They interact with one another to destroy foreign body (microorganisms, infected cell ...
Chapter 43 PowerPoint
Chapter 43 PowerPoint

... • Contacts helper T cell (has complementary receptors) • Macrophage secretes IL-1 – activated helper T cells • (T cells do not recognize an antigen presented ...
Heamatological parameters and cellular morphological
Heamatological parameters and cellular morphological

... and oriented centrally. Variations in the erythrocyte count based on the metabolic activity were reported in amphibians (Goniakowska, 1973 ; Kuramoto 1981). In this study the white blood cell proportions of infected frogs appeared with the most cell type being lymphocytes (47.5%) of white blood cell ...
Immunology. Mucosal and Body Surface Defences Brochure
Immunology. Mucosal and Body Surface Defences Brochure

... The vast majority of medically important pathogens infect their host across a body surface such as the skin, or across a mucosal tissue such as the respiratory tract or intestines, as these sites are the ones exposed to the external environment. By focusing on immunity at mucosal and body surfaces t ...
Immunology
Immunology

...  Activation of macrophages leads to enhanced Ag presentation, killing and cytokine secretion o IL-12: differentiation and activation of TH1 cells o PDGF and TGFβ: proliferation of fibroblasts o Histopathologic Findings: ...
T cells - immunology.unideb.hu
T cells - immunology.unideb.hu

Document
Document

type I
type I

... area resulting in itching. • Airway sensitivity results in sneezing and rhinitis OR wheezing and asthma. ...
Poster
Poster

... destruction, leading to clotting disorder. Interestingly, mother responders are characterized by the expression of class II HLA DRB3*0101 (also known as DRw52a with other nomenclature) on the surface of Antigen Presenting Cells. Class II HLA molecules play an important role in the initiation of the ...
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Lymphopoiesis



Lymphopoiesis (lĭm'fō-poi-ē'sĭs) (or lymphocytopoiesis) is the generation of lymphocytes, one of the five types of white blood cell (WBC). It is more formally known as lymphoid hematopoiesis.Pathosis in lymphopoiesis leads to any of various lymphoproliferative disorders, such as the lymphomas and lymphoid leukemias.
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