Soft sensor application on lactate controlled fed-batch
... model use constant yield coefficients which can be a drawback when using soft sensors due to their inflexibility to handle upcoming problems caused by environmental changes and is therefore more suited for batch cultivations. A structured model can be used for changing yield coefficients and is ther ...
... model use constant yield coefficients which can be a drawback when using soft sensors due to their inflexibility to handle upcoming problems caused by environmental changes and is therefore more suited for batch cultivations. A structured model can be used for changing yield coefficients and is ther ...
What is the basis of an allergic reaction
... When possible the allergen should be avoided and when this is not feasible as in the case of airborne pollens, then allergen immunotherapy may be an option. This method desensitizes a person to the allergen, which can prevent future reactions or reduce the severity (Merck, 2003). For anaphylaxis, ad ...
... When possible the allergen should be avoided and when this is not feasible as in the case of airborne pollens, then allergen immunotherapy may be an option. This method desensitizes a person to the allergen, which can prevent future reactions or reduce the severity (Merck, 2003). For anaphylaxis, ad ...
Interference of passive and active immunity after vaccination of pigs
... the antigen specific proliferation of lymphocytes. In addition, we investigated the nature of protective immunity induced by systemic delivery of glycoprotein E (gE)-deleted attenuated vaccine (the Th1–Th2 polarization of immune response) by examining the profile of Th1 and Th2 cytokines produced by ...
... the antigen specific proliferation of lymphocytes. In addition, we investigated the nature of protective immunity induced by systemic delivery of glycoprotein E (gE)-deleted attenuated vaccine (the Th1–Th2 polarization of immune response) by examining the profile of Th1 and Th2 cytokines produced by ...
Can We Selectively Shut Off Immune Responses?
... The immune system is organized into innate and adaptive components. The innate system serves as the first line of defense. The innate system uses nonspecific cells such as phagocytic cells to interact with the microbe and protect the host. Natural killer cells are important in the innate response be ...
... The immune system is organized into innate and adaptive components. The innate system serves as the first line of defense. The innate system uses nonspecific cells such as phagocytic cells to interact with the microbe and protect the host. Natural killer cells are important in the innate response be ...
The New Golden Era for Radioimmunotherapy
... companies/organizations whose products or services may be referenced in this article. Dr Tomblyn has received research support from Immunomedics, Inc. Dr Wallner was the chair of the American Society for Radiation Oncology’s Systemic Targeted Radionuclide Therapy program. 60 Cancer Control ...
... companies/organizations whose products or services may be referenced in this article. Dr Tomblyn has received research support from Immunomedics, Inc. Dr Wallner was the chair of the American Society for Radiation Oncology’s Systemic Targeted Radionuclide Therapy program. 60 Cancer Control ...
LEARNING OBJECTIVE 1: Describe the general functions of the
... or infectious origin. Symptoms include painless lymph nodes, nonspecific malaise, fever, weight loss, itching of skin, and the presence of large, atypical macrophages. Remission is common. 3. Anaphylaxis—A hypersensitivity reaction influenced by IgE antibodies. The reaction may be localized (rash, w ...
... or infectious origin. Symptoms include painless lymph nodes, nonspecific malaise, fever, weight loss, itching of skin, and the presence of large, atypical macrophages. Remission is common. 3. Anaphylaxis—A hypersensitivity reaction influenced by IgE antibodies. The reaction may be localized (rash, w ...
"Immunological Accessory Molecules".
... FcgR1 (CD64) is expressed mainly by macrophages and dendritic cells, and promotes phagocytosis of immune complexes, which are antigens or microbes bound by antibody molecules. FcgRII (CD32) is present on monocytes, granulocytes and B cells. CD32 is involved in phagocytosis and ADCC, degranulation of ...
... FcgR1 (CD64) is expressed mainly by macrophages and dendritic cells, and promotes phagocytosis of immune complexes, which are antigens or microbes bound by antibody molecules. FcgRII (CD32) is present on monocytes, granulocytes and B cells. CD32 is involved in phagocytosis and ADCC, degranulation of ...
Immune System Function
... – MHC-I which are found on all nucleated cells of the body – MHC-II which are found on macrophages, dendritic cells and B cells = antigen presenting cells (APCs) ...
... – MHC-I which are found on all nucleated cells of the body – MHC-II which are found on macrophages, dendritic cells and B cells = antigen presenting cells (APCs) ...
... tumor cells. It can also be produced against a peptidic antigen, including the amino acid TGLAA (SEQ ID NO: 2) or YTG LAA (SEQ ID NO: 3), if appropriate coupled to a carrier protein. In a further embodiment, the antibodies are produced by means of a bone sialoprotein, modi?ed in its glycosyla tion, ...
CTL - Molecular Immunology
... • Antigen presentation does not require metabolically-active cells • Antigen processing involves the lysosomal system • Catabolism reduces antigens to peptides • Because extracellular antigens are dealt with by the lysosomal system, lysosomal antigen processing is part of the EXOGENOUS antigen proce ...
... • Antigen presentation does not require metabolically-active cells • Antigen processing involves the lysosomal system • Catabolism reduces antigens to peptides • Because extracellular antigens are dealt with by the lysosomal system, lysosomal antigen processing is part of the EXOGENOUS antigen proce ...
T cells - immunology.unideb.hu
... The TCR-specific peptide is recognized only when its presented with an MHC on which the TCR had been selected during its development in the thymus If the peptide binds to another MHC molecule no T-cell recognition occurs (by this T cell) ...
... The TCR-specific peptide is recognized only when its presented with an MHC on which the TCR had been selected during its development in the thymus If the peptide binds to another MHC molecule no T-cell recognition occurs (by this T cell) ...
Full-Text PDF
... recognized by distinct receptors. The effector responses triggered lead to a chronic tissue inflammation. DsDNA autoantibodies are the most studied as well as the first in being characterized for its pathogenic role in Lupus nephritis. However, others are of growing interest since they have been ass ...
... recognized by distinct receptors. The effector responses triggered lead to a chronic tissue inflammation. DsDNA autoantibodies are the most studied as well as the first in being characterized for its pathogenic role in Lupus nephritis. However, others are of growing interest since they have been ass ...
(From the Variety Club Heart Hospital Pediatric Research
... resistance. Although some of these are well developed in invertebrates and m a y indeed be the effective mechanisms of defense, they have been reviewed heretofore (I) and will not be considered in this paper. Contact with antigen is an event necessary for the immunologic maturation of lymphoid cells ...
... resistance. Although some of these are well developed in invertebrates and m a y indeed be the effective mechanisms of defense, they have been reviewed heretofore (I) and will not be considered in this paper. Contact with antigen is an event necessary for the immunologic maturation of lymphoid cells ...
Am“B”valent: anti-CD20 antibodies unravel the dual
... The association between autoimmune diseases and hematologic malignancies has long been recognized. Although autoimmune conditions associated with hematologic malignancies can affect any organ, they seem to predominantly target blood constituents.28 The pathophysiology of these autoimmune manifestati ...
... The association between autoimmune diseases and hematologic malignancies has long been recognized. Although autoimmune conditions associated with hematologic malignancies can affect any organ, they seem to predominantly target blood constituents.28 The pathophysiology of these autoimmune manifestati ...
tolerance
... * The nature of cells presenting antigenic epitopes * The number of lymphocytes able to respond * Microenvironment of encounter (expression of cell adhesion molecules, influence of cytokines etc.) ...
... * The nature of cells presenting antigenic epitopes * The number of lymphocytes able to respond * Microenvironment of encounter (expression of cell adhesion molecules, influence of cytokines etc.) ...
Overview ...........................................................
... To help them solve the mystery, scientists rely on computers to help them organize data, in a field called bioinformatics. Students learn that scorpion venom, while harmful in some ways, may be useful in treating cancer. Therefore scientists are very interested in studying this, and all kinds of pro ...
... To help them solve the mystery, scientists rely on computers to help them organize data, in a field called bioinformatics. Students learn that scorpion venom, while harmful in some ways, may be useful in treating cancer. Therefore scientists are very interested in studying this, and all kinds of pro ...
Basic immunology
... molecules from the cell whilst activation of the latter inhibits the aforesaid action. NK cells serve an important role in attacking virally-infected cells in addition to certain tumour cells. Destruction of infected cells is achieved through the release of perforins and granyzymes from its granules ...
... molecules from the cell whilst activation of the latter inhibits the aforesaid action. NK cells serve an important role in attacking virally-infected cells in addition to certain tumour cells. Destruction of infected cells is achieved through the release of perforins and granyzymes from its granules ...
Methods in Cell Biology
... Radioactive probe (amino acids, nucleotides) Specimen must be alive to monitor metabolic events Can be used with other stains Slide dipped in photographic emulsion & developed Silver grains where radioactive material is present in ...
... Radioactive probe (amino acids, nucleotides) Specimen must be alive to monitor metabolic events Can be used with other stains Slide dipped in photographic emulsion & developed Silver grains where radioactive material is present in ...
Immunology of Transplantation & Malignancy
... immunogenic or they may fail to express costimulatory molecules for the activation of Tcells. In addition, certain tumors are known to lack or be poor expressers of MHC antigen The amount of antigen may be too small to stimulate the immune system and, due to the rapid proliferation of malignant cell ...
... immunogenic or they may fail to express costimulatory molecules for the activation of Tcells. In addition, certain tumors are known to lack or be poor expressers of MHC antigen The amount of antigen may be too small to stimulate the immune system and, due to the rapid proliferation of malignant cell ...
The Essential Role of T cells in Multiple Sclerosis: A Reappraisal
... In MS, we and others have shown that Th17 cells are up‑regulated, and that cells expressing both IL‑17 and IFN‑g (Th1–17) are the most up‑regulated in MS relapse.[28] This group of cells has been shown to inflict most damage to the BBB.[29] The above data suggest that it would make sense to neu‑ tra ...
... In MS, we and others have shown that Th17 cells are up‑regulated, and that cells expressing both IL‑17 and IFN‑g (Th1–17) are the most up‑regulated in MS relapse.[28] This group of cells has been shown to inflict most damage to the BBB.[29] The above data suggest that it would make sense to neu‑ tra ...
Waldenstrom`s Macroglobulinemia Basic Immunology
... molecule on the surface of an infectious agent (e.g. bacteria, virus, or other pathogen) is called an antigen. An immunogen is an antigen capable of inducing an immune response. Immunogenic compounds are usually characterized as being foreign to the individual, having a high molecular weight (large ...
... molecule on the surface of an infectious agent (e.g. bacteria, virus, or other pathogen) is called an antigen. An immunogen is an antigen capable of inducing an immune response. Immunogenic compounds are usually characterized as being foreign to the individual, having a high molecular weight (large ...
Immune System
... Mature into either plasma cells or memory B cells. Mature to produce an anti body against the antigen which caused its production. Mature in bone marrow ...
... Mature into either plasma cells or memory B cells. Mature to produce an anti body against the antigen which caused its production. Mature in bone marrow ...
Skin fibroblast culture
... medium, at 37o C. The reactions were stopped on ice, at various times (0, 15, 30, 45, 60 minutes). Dexamethasone (5M), a testosterone structural analog, was added as a recovery standard. Steroids were extracted from the culture medium with ethyl acetate (Baltes and Hanocq, 1998), followed by vacuum ...
... medium, at 37o C. The reactions were stopped on ice, at various times (0, 15, 30, 45, 60 minutes). Dexamethasone (5M), a testosterone structural analog, was added as a recovery standard. Steroids were extracted from the culture medium with ethyl acetate (Baltes and Hanocq, 1998), followed by vacuum ...
Monoclonal antibody
Monoclonal antibodies (mAb or moAb) are monospecific antibodies that are made by identical immune cells that are all clones of a unique parent cell, in contrast to polyclonal antibodies which are made from several different immune cells. Monoclonal antibodies have monovalent affinity, in that they bind to the same epitope.Given almost any substance, it is possible to produce monoclonal antibodies that specifically bind to that substance; they can then serve to detect or purify that substance. This has become an important tool in biochemistry, molecular biology and medicine. When used as medications, the non-proprietary drug name ends in -mab (see ""Nomenclature of monoclonal antibodies""), and many immunotherapy specialists use the word mab anacronymically.