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Topic 4: Human Body Page 1 Base your
Topic 4: Human Body Page 1 Base your

... 20. Describe one example of diffusion in the human body. In your description be sure to:  • identify the place where diffusion takes place   • identify a substance that diffuses there • identify where that substance diffuses from and where it diffuses to, at that place ...
Cardiovascular System
Cardiovascular System

... 5. __________________________ -confines & removes microbes at point of damage and repairs tissue. 6. _________________________ - slows microbial growth & speeds repair. II. Immunity or Specific Resistance A. General Info ...
Teaching Notes
Teaching Notes

... To understand the function of the immune system, it is helpful to understand the various cells, proteins and complexes involved and relate them to their function. Key ideas: 1. The immune response is a complex set of reactions that relies on interplay among the different cells. 2. Cells communicate ...
Contraction of lymphatic vessels
Contraction of lymphatic vessels

...  And adjacent cells overlap, forms minivalves Function of mini – valve : Act as one-way gate  Allow interstitial fluid to enter lymph capillaries  Do not allow lymph to go back to interstitial space ...
1 Detection of Histatherin: a Potential Antimicrobial Peptide K
1 Detection of Histatherin: a Potential Antimicrobial Peptide K

... century. In recent times, due to a combination of overusing, misusing and declining research and development of antibiotics, resistance among pathogens has become endemic. Since the 1950’s antimicrobial peptides produced by higher order organisms such as cows, sheep and goats have been investigated. ...
Kuby Immunology 6/e
Kuby Immunology 6/e

... Early in hematopoiesis, stem cell differentiates to either ○ Lymphoid progenitor cell ○ Myeloid progenitor cell - Progenitor cells have lost ability for self renewal and are committed to particular cell lineage ...
Streptococcal Serology powerpoint
Streptococcal Serology powerpoint

... • Associated with large amount of M protein and a capsule • Due to immune response against Strep antigens similar to heart antigens. ...
Brochure - ECFG21 Electro-Cell Fusion Generator
Brochure - ECFG21 Electro-Cell Fusion Generator

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Session 2
Session 2

... Transplant rejection is a process in which a transplant recipient's immune system attacks the transplanted organ or tissue. These harmful substances have proteins called antigens on their surfaces. As soon as these antigens enter the body, the immune system recognizes them as foreign and attacks the ...
Chapter 22 The Lymphatic System, Nonspecific Resistance to
Chapter 22 The Lymphatic System, Nonspecific Resistance to

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Is an HIV Vaccine Possible? - College of Health Sciences, University
Is an HIV Vaccine Possible? - College of Health Sciences, University

... Ongoing Phase 1 clinical trials Protocol B002 • Recombinant Fusion protein (F4co) in adjuvant (ASO1B or ASO1E) + replication incompetent Ad35-GRIN • F4co [p24-RT-Nef-p17 of HIV-1clade B Gag, Pol, Nef)] • Ad35-GRIN [with HIV-1 clade A gag, RT, integrase, nef) • Phase 1, double blind, randomized plac ...
Hemoglobin - Huntingdon College
Hemoglobin - Huntingdon College

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Question 1

... d) Macrophages kill bacterial microbes by secreting a chemical that punches holes in the bacterial membrane. Macrophages kill bacterial microbes by ingesting and lysing. or Complement kills bacterial microbes by punching holes in the bacterial membrane. e) A single B cell can produce many different ...
IMMUNE SYSTEM
IMMUNE SYSTEM

... • Loss of tolerance to self antigen, therefore, there is auto immune disease (auto means against self) Why it occurs? It is due to combination of genetic and environmental factors e.g. modification by virus, drugs, bacteria ...
Breast Cancer: FISH for ERBB2 (HER2)
Breast Cancer: FISH for ERBB2 (HER2)

... associated with poor prognosis however they are likely to respond to certain chemotherapeutic regimes. Furthermore, these patients appear to respond favorably with the humanized monoclonal antibody Herceptin, either as a single agent or in combination. ...
Specific Immunity and Immunization
Specific Immunity and Immunization

... • Recombinant DNA technology • Trojan horse vaccine – Genetic material from an infectious agent is inserted into a live carrier microbe that is nonpathogenic – The recombinant microbe multiplies and expresses the foreign genes – The vaccine recipient will be immunized against the microbial antigens ...
Q fever
Q fever

... Zealand. – esp. prevalent in meatworks, dairies and animal farms therefore making Q fever an occupational hazard ...
Chapter 2
Chapter 2

... Early in hematopoiesis, stem cell differentiates to either ○ Lymphoid progenitor cell ○ Myeloid progenitor cell - Progenitor cells have lost ability for self renewal and are committed to particular cell lineage ...
The novel EpCAM-targeting monoclonal antibody 3–17I linked to
The novel EpCAM-targeting monoclonal antibody 3–17I linked to

... Photochemical internalization (PCI) is a drug delivery technology for local and light controlled cytosolic release of therapeutics entrapped in endosomes and lysosomes, where the effect will be confined to the illuminated area only. PCI is based on the use of a photosensitizer, as in photodynamic th ...
Suggested Intervals between Administration of Antibody-Containing Products and Measles-Containing and Varicella-Containing Vaccines (adopted from the ACIP General Recommendations, 2006, Table 4) (PDF)
Suggested Intervals between Administration of Antibody-Containing Products and Measles-Containing and Varicella-Containing Vaccines (adopted from the ACIP General Recommendations, 2006, Table 4) (PDF)

... every effort to obtain and administer VariZIG. In situations in which administration of VariZIG does not appear possible within 96 hours of exposure, administration of immune globulin intravenous (IGIV) should be considered as an alternative. IGIV also should be administered within 96 hours of expo ...
Wegener`s Granulomatosis
Wegener`s Granulomatosis

... and anti-MPO antibodies RAG-2 deficient mice (lacking T- and B- cells) that received anti-MPO splenocytes developed crescentic GN and systemic necrotizing vasculitis. Immunization with non-MPO antibody producing splenocytes displayed only a mild immune ...
Nervous system - local
Nervous system - local

... Antigens are recognized through specific receptors located in the plasma membranes of the B and T cells. • B cells can give rise to plasma cells that secrete antibodies, which are soluble forms of antigen receptors. ...
Chapter 3. Antigens
Chapter 3. Antigens

... Antigen: Substances that can be recognized by the surface antibody (B cells) or by the TCR (T cells) when associated with MHC molecules Immunogenicity VS Antigenicity: Immunogenicity – ability to induce an antibody and/or cell-mediated immune response Antigenicity – ability to combine with the final ...
Chapter 2. Immunology System
Chapter 2. Immunology System

... weigh of 60,000 can have six different epitopes and react with six different paratopes and different antibodies. There can be as many different species of antibodies (or effector T cell clones) produced as there are functional epitopes on an antigen. Hapten An incomplete antigen (hapten) is a chemic ...
PowerPoint to accompany
PowerPoint to accompany

... The first thing to remember is that most microorganisms arriving at the external surfaces of the body fail to establish a colony. Just as in military strategy, the hardest thing for an invader to do is to establish a beachhead. So one cardinal property which distinguishes microorganisms capable of c ...
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Monoclonal antibody



Monoclonal antibodies (mAb or moAb) are monospecific antibodies that are made by identical immune cells that are all clones of a unique parent cell, in contrast to polyclonal antibodies which are made from several different immune cells. Monoclonal antibodies have monovalent affinity, in that they bind to the same epitope.Given almost any substance, it is possible to produce monoclonal antibodies that specifically bind to that substance; they can then serve to detect or purify that substance. This has become an important tool in biochemistry, molecular biology and medicine. When used as medications, the non-proprietary drug name ends in -mab (see ""Nomenclature of monoclonal antibodies""), and many immunotherapy specialists use the word mab anacronymically.
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