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Better Lesion Creation And Assessment During Catheter
Better Lesion Creation And Assessment During Catheter

... end of the procedure, long term efficacy of catheter ablation remains soberingly modest, with single and multiple procedure success rates of 54% and 79% recently reported for paroxysmal AF over long term follow up (≥ 3 years).14 The time-dependent inevitability of PV reconnection and its relationshi ...
Level of Evidence
Level of Evidence

... Auer, J., R. Berent, et al. (2001). "Amiodarone. Renaissance of an antiarrhythmic drug?" Internistische Praxis ...
Intercellular Coupling Abnormalities in the Heart: Quantification from
Intercellular Coupling Abnormalities in the Heart: Quantification from

... Cardiac conduction velocity is one of the most important electrophysiological characteristics of the heart. Several cardiac dysfunctions and arrhythmia are caused by slowed conduction velocity. Measurement of cardiac conduction velocity and other physiological characteristics of the heart such as an ...
Implantable Cardioverter Defibrillators (ICDs)
Implantable Cardioverter Defibrillators (ICDs)

... Microwave ovens and other appliances should not cause problems. Neither should computers, hair dryers, power tools, radios, televisions, electric blankets, or cars. Signals from a few devices might cause problems with your ICD, though. Take care to avoid these. ...
New Insights into Mechanisms of Atrial Fibrillation
New Insights into Mechanisms of Atrial Fibrillation

... 15% of all strokes are attributable to this disorder. AF is characterized by very rapid, chaotic electrical activity of the atria, resulting in accelerated and irregular ventricular activity, loss of atrial mechanical function and increased risk of atrial clot formation. AF can occasionally affect a ...
Single Preconditioning Stimulus Becomes
Single Preconditioning Stimulus Becomes

... more strong ischemic challenge causes the more significant protection. There were no significant differences in hemodynamics between groups, which provides an additional evidence for local (intracardiac) nature of the protective IPC mechanism. The pattern of antiarrhythmic IPC action showed in the p ...
Congestive Heart Failure Educational Handbook
Congestive Heart Failure Educational Handbook

... The heart has four chambers – the two upper chambers are the left and right atria, and the two lower chambers are the left and right ventricles. The right side of the heart pumps blood from the body to the lungs for oxygen; whereas, the left side pumps blood from the lungs to the body. Damage to the ...
Special Report
Special Report

... from primary prevention interventions. Data from Europe and North America suggest that the age-adjusted incidence and prevalence of AF are increasing.21–26 Based solely on the aging of the population, the prevalence of AF in the United States has been projected to increase from ⬇2 to 5 million in 20 ...
The role of endomyocardial biopsy in the management of
The role of endomyocardial biopsy in the management of

... forceps (Stanford Caves-Shulz bioptome) to allow percutaneous biopsies through the right internal jugular vein with only local anesthesia and rapid tissue removal. The reusable Stanford-Caves bioptome and its subsequent modifications became the standard device for EMB for approximately 2 decades.6,7 ...
ANTIARRHYTHMIC THERAPY FOR ATRIAL
ANTIARRHYTHMIC THERAPY FOR ATRIAL

... shown to exhibit significant intra-atrial conduction delays during early premature impulses delivered at the low right atrium (18). These delays can be explained on the basis of nonuniform atrial anisotropy (18). If it were so, the nonuniform atrial anisotropy would lead to new treatment for AF: the ...
The EP Show
The EP Show

... A major limitation of the the major ICD trials is that follow-up was only two to three years but the disease is a chronic one "The severity of the underlying heart disease is a moving target, and the sad reality is that the trajectory of the severity of heart disease is such that most patients over ...
Pathogenesis of ventricular hypertrophy
Pathogenesis of ventricular hypertrophy

... Heart size and left ventricular wall tension and pressure. Cardiac muscle normally grows to compensate for the work load imposed on the ventricle. Classically, the most important factor mediating cardiac hypertrophy has been thought to be the systolic force or tension generated by the myocardial fib ...
Assessment of systolic and diastolic ventricular properties - AJP
Assessment of systolic and diastolic ventricular properties - AJP

... quency relationship; Ref. 49) and even on a beat-to-beat basis when the interval between successive contractions is varied as on extrasystolic and postextrasystolic contractions (the socalled force-interval relationship; Refs. 14, 93). Because of these basic features (load independence and sensitivi ...
Morphological Changes of the QRS Complex as a Marker of
Morphological Changes of the QRS Complex as a Marker of

... patients with acute myocardial infarction [Ravenswaaij-Arts et al. 1993]. Moreover, observations of patients with congestive heart failure show alterations of the sympathovagal balance; the general consensus seems to be that there is a sympathetic overdrive rather than a parasympathetic withdrawal a ...
Temporal Dilation of Animal Cardiac Recordings Registered to
Temporal Dilation of Animal Cardiac Recordings Registered to

... on the underlying assumption that CV should remain constant after mapping due to consistent cellular structure of the myocardium between canines and humans. To show physiological relevance following temporal, validation using conduction parameters was performed. ...
The Relationship Between Atrial Fibrillation and Chronic
The Relationship Between Atrial Fibrillation and Chronic

... Hypertension is both a cause and consequence of CKD, with the majority of CKD patients affected by systemic hypertension.57 Moreover, with sodium retention, activation of the renin-angiotensin aldosterone system (RAAS), and sympathetic nervous system up-regulation, hypertension becomes increasingly ...
AHA/ACCF/ESC Scientific Statement
AHA/ACCF/ESC Scientific Statement

... internal jugular vein, sampling of the right interventricular septum, and designation of the heart borders by right heart catheterization before biopsy.3 Sakakibara and Konno4 introduced the use of a flexible bioptome with sharpened cusps that allowed EMB by a pinching as opposed to a cutting techni ...
Molecular and Cellular Basis for Diastolic Dysfunction
Molecular and Cellular Basis for Diastolic Dysfunction

... colocalize with caveolin at plasma membrane invaginations, called caveolae, which may serve as microdomains for optimized NO-sGC-cGMP signaling [52•, 57]. In addition, NP-mediated activation of cGMP-PKG signaling is spatially confined to a distinct subcellular compartment. Natriuretic peptides stimu ...
Heart Failure: Causes and Nursing Management
Heart Failure: Causes and Nursing Management

... most common causes of mitral insufficiency and most valvular disorders. This causes a backflow of blood from the left ventricle into left atrium and affects more women than men in 30% of the population. Aortic stenosis causes the aortic valve to narrow, while in aortic insufficiency, blood enters th ...
The Artificial Pacemaker . . . . . . A Pure Success Story!?
The Artificial Pacemaker . . . . . . A Pure Success Story!?

... implanted in several million patients, thus, preventing the death of a significant number of patients. Considering the importance of pacemakers in modern medical science, the number of people already depending on the support of pacemakers as well as the steady improvement of the implants and their f ...
Endocardial endothelium in the avascular frog heart - AJP
Endocardial endothelium in the avascular frog heart - AJP

... also known to regulate O2 consumption under a variety of conditions (2, 12, 15, 22, 25). This regulation of myocardial metabolism may be one of NO’s most significant roles. We have proposed that endothelial NO synthase (eNOS), which is the most highly expressed isoform of NOS in vascular tissue unde ...
Quinidine for Pharmacological Cardioversion of Atrial Fibrillation: A
Quinidine for Pharmacological Cardioversion of Atrial Fibrillation: A

... Ann Noninvasive Electrocardiol 2009;14(2):128–136 atrial fibrillation; quinidine; pharmacological cardioversion; drug safety; adverse drug reaction ...
Primary Prophylaxis of Sudden Death in Hypertrophic
Primary Prophylaxis of Sudden Death in Hypertrophic

... have simple ectopy, sustained and nonsustained VT, or ventricular fibrillation. ARVC needs to be ruled out when VT originates from the RV outflow region. Idiopathic RV outflow VT is usually not associated with the ECG abnormalities seen with ARVC, is more common in women, and is exercise induced or ...
Spotlight on atrial fibrillation—the `complete arrhythmia`
Spotlight on atrial fibrillation—the `complete arrhythmia`

... conduction delays and fragmented electrograms are more common in AF. Brundel et al. discuss the available information regarding molecular mechanisms of remodeling in human AF [33]. The evidence for ion-channel remodeling at the mRNA and protein levels is reviewed, as are changes in proteins determin ...
DETERMINANTS OF CARDIAC FUNCTION: SIMULATION OF A
DETERMINANTS OF CARDIAC FUNCTION: SIMULATION OF A

... HR while displaying time-dependent changes in pressure and volume in addition to a pressure-volume plot. It differs from previous models (1, 3, 5) by graphing these parameters on a beat-to-beat basis that is particularly useful when describing the dynamic adaptation of the pumping heart to various s ...
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Heart arrhythmia

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