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Pharmacology of Antiarrhythmics and Vasoactive Substances
Pharmacology of Antiarrhythmics and Vasoactive Substances

... Class IB antiarrhythmic • blocks fast sodium channels • decreases slope of phase 4 • decreased automaticity in the His-purkinje system • action potential duration and effective refractory period of His-purkinje increased • Acts preferentially on ischemic tissue ...
Case rounds: chest pain
Case rounds: chest pain

... antidromic reciprocating tachycardia (AV reentry with atrial to ventricular conduction) ...
1. The diagram below shows a section through the human heart
1. The diagram below shows a section through the human heart

... 6. Tissue fluid (bathes the cells). 7. Plasma proteins do not pass through capillary walls/stay in blood. 8. (Dissolved) substances diffuse/move from tissue fluid into body cells. 9. Waste products/named example diffuse /move out of the cells. 10. To be excreted/carbon dioxide breathed out. 11. Liqu ...
Medicine and Computers
Medicine and Computers

... Automated External Defibrillator: Jump-Starting the Heart ...
hypertrophic obstructive cardiomyopathy
hypertrophic obstructive cardiomyopathy

... pattern can disrupt the heart’s rhythm resulting in irregular beats. 3. The left ventricle becomes stiff. The disorganized cells prevent the muscle from relaxing and stretching, reducing the amount of blood that can fill the heart. When less blood is pumped forward into the body, blood can back up a ...
Atrial Fibrillation
Atrial Fibrillation

... http://www.youtube.com/watch?v=ZFWMB42Y0KE Holmes DR et al, Lancet 2009 Aug 15;374(9689):534-42 Fountain RB et al, Am Heart J 2006;151(5):956–61. ...
Atrial Fibrillation and Sudden Cardiac Death
Atrial Fibrillation and Sudden Cardiac Death

... advanced cardiovascular disease, including hypertrophy or HF, either with reduced or preserved ejection fraction (EF). The AF–SCD relationship may thus be a confounded one. In the 18,000-patient RE-LY (Randomized Evaluation of Long Term Anticoagulant Therapy) trial, 20% of deaths were due to SCD, an ...
Postural Tachycardia Syndrome
Postural Tachycardia Syndrome

... spots in the field of vision, and ultimately loss of consciousness. At present, we define POTS as an excessive increase in heart rate associated with symptoms of more than 3 months’ duration (in the absence of other conditions that could mimic this such as dehydration). In POTS, the heart rate incre ...
Read article - Heart Rhythm Alliance
Read article - Heart Rhythm Alliance

... spots in the field of vision, and ultimately loss of consciousness. At present, we define POTS as an excessive increase in heart rate associated with symptoms of more than 3 months’ duration (in the absence of other conditions that could mimic this such as dehydration). In POTS, the heart rate incre ...
THE GIANT HEART The Museum`s new Giant Heart is a vibrant
THE GIANT HEART The Museum`s new Giant Heart is a vibrant

... The Museum’s new Giant Heart is a vibrant, three-dimensional structure—both virtual and physical—that modernizes the idea of the Museum’s old iconic walk-through heart and serves as the centerpiece of YOU! The Experience. The Giant Heart stands more than 13-feet high and eight-feet wide. A remarkabl ...
Persistent Atrial Fibrillation And Atrial Flutter Complicated By
Persistent Atrial Fibrillation And Atrial Flutter Complicated By

... runs of wide complex tachycardia. Indeed this clinical case shows us the hard dilemma of wide QRS during atrial fibrillation: ventricular ectopy, preexcitation or aberrant ventricular conduction?6 We immediately ruled out the third ipothesis: the QRS morphology was not aberrant and there was no Ashm ...
ALH 3205 Professor Cohen 9/02/2009 Cardiac Physiology Anatomy
ALH 3205 Professor Cohen 9/02/2009 Cardiac Physiology Anatomy

... walls a little  have a greater distance to contract = greater force of contraction  All areas of heart are auto-rhythmic –  SA Node is spontaneously active  Pacemaker Potential – bc membranes of cells that make up the SA Node are not effective at keeping NA+ ions out  When NA+ ions enter a cell ...
Six Heart Healthy Actions
Six Heart Healthy Actions

... rhythms) and be at risk of sudden cardiac arrest (SCA). But those with heart disease are at the highest risk. Reducing heart disease is important to help lower the risk of arrhythmias, stroke and SCA. This February Heart Health Month, you can take action to prevent and treat heart problems such as a ...
(SA) node
(SA) node

... sustained contraction (tetany) in cardiac muscle and ensures that filling time (diastole) occurs. ...
113915_Heart_Disection
113915_Heart_Disection

... of hearts, we will be working in fairly large groups. Please make sure that you share. If you are not interested in touching or working with the heart, please have a group member report the observations to you. ...
The Heart
The Heart

... devices that hold blood vessel open after angioplasty; can prevent re-occlusion of blood vessel. ...
A1993MB49000001
A1993MB49000001

... experiences a high level of cardiac adrenergic drive, which then results in receptor pathway desensitization. We subsequently demonstrated that although both (3, and R2 receptors are present in the human heart, the receptor which down-regulates is the 3, receptor. Although we and others also demonst ...
Pacemaker - Louisiana Heart Center
Pacemaker - Louisiana Heart Center

... ventricle. These pacemakers first make the atria contract and pump blood to the ventricles, and then they stimulate the ventricle for it to contract. This is more effective and allows a greater volume of blood to be pumped with each beat. Another more sophisticated type of pacemaker monitors physica ...
phys chapter 10 [12-11
phys chapter 10 [12-11

... fibers), and they transmit APs at 1.5-4.0 m/sec (6x faster than that in usual ventricular muscle and 150x that in some AV nodal fibers)  Rapid transmission caused by very high level of permeability of gap junctions at intercalated discs between successive cells that make up Purkinje fibers; ions ar ...
Name - UW Canvas
Name - UW Canvas

... useful in patients with heart failure by protecting against cardiac dysrhythmias and protecting the heart from excessive sympathetic stimulation and subsequent downregulation of beta receptors (remember the speakers example when she used her hands to explain downregulation). Also, beta blockers will ...
ECG Leads
ECG Leads

...  Instruct the patient to remain still (should not talk during the test ) and relax their shoulders and legs while the recording takes place (1 min) ...
Sudden Cardiac Death
Sudden Cardiac Death

... clinical status – ‘clinically well one hour ago and dead one hour after due to cardiovascular disease’. ...


... the p-wave morphology is negative in leads II, III and AVF, supporting the notion that this dysrhythmia originates from a focus of enhanced automaticity in the peri-AV nodal region. The heart rate typically rises and decreases gradually (warms up and cools down). This feature helps differentiate it ...
Drug therapy for rate control Beta
Drug therapy for rate control Beta

... despite optimal pharmacological treatment, have a further option: radiofrequency catheter ablation of the AV node, which achieves both rate control and regularisation of the ventricular rate.51 This necessitates implantation of, and dependency on, a permanent pacemaker in all cases so is typically r ...
Chapter 20
Chapter 20

... --Purkinje Fibers: from bundle branches *pacemaker rates: 20-40 times/minute (fibers in ventricles) *Conduction speed: FASTEST 4 m/s --Timing of Atrial and Ventricular Excitation *50msec spreads through both atria and down to AV node *100msec DELAY at AV node due to smaller diameter fibers (atria ca ...
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Heart arrhythmia

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