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Test Review on DNA Structure, DNA Replication
Test Review on DNA Structure, DNA Replication

...  Understand that the nitrogen base is the part of the nucleotide that forms the genetic code, and be able to name the four possible nitrogen bases in a DNA nucleotide.  Know how the nucleotides are organized in the strands  Know the complementary nitrogen base pairings Be able to explain the over ...
Test Review on DNA Structure, DNA Replication
Test Review on DNA Structure, DNA Replication

...  Understand that the nitrogen base is the part of the nucleotide that forms the genetic code, and be able to name the four possible nitrogen bases in a DNA nucleotide.  Know how the nucleotides are organized in the strands  Know the complementary nitrogen base pairings Be able to explain the over ...
F4-6 Gene Regulation and Mutation Ch12,13
F4-6 Gene Regulation and Mutation Ch12,13

... a. Old way to achieve desired traits b. Only breed animals/plants with desired traits c. After many generations – new pure breed 2. Genetic Engineering a. manipulate DNA of one organism to insert DNA of another b. Restriction enzymes – recognize specific DNA sequences and cut out the DNA c. Gel elec ...
DNA, Transcription and Translation
DNA, Transcription and Translation

... Transcription = rewriting or copying of information from DNA to ribonucleic acid ( RNA). Occurs in the nucleus. RNA is a single stranded molecule containing the sugar ribose, phosphate and the bases Adenine, Guanine, Cytosine and Uracil. The synthesised RNA is complementary to one strand of DNA. In ...
Document
Document

... Translation- Translating language of nucleic acids (base sequences) into language of proteins (amino acids) 1. Gene on DNA carries code to make protein a. Code written in language with only 4 “letters”, the nitrogen bases A,C,G,U ...
DNA, RNA, Genes, Chromosomes
DNA, RNA, Genes, Chromosomes

... can result in disease. Each gene acts as a blueprint for making a specific enzyme or other protein. However, only certain genes in a cell are active at any given moment and, as cells mature, many of their genes become permanently inactive. It is the pattern of active and inactive genes in a cell and ...
DNAi Timeline: A Scavenger Hunt
DNAi Timeline: A Scavenger Hunt

... 1. It took him eight years and more than 10,000 pea plants to discover the laws of inheritance. ________________________________________ 2. He determined base pairing rules. A-T and G-C _______________________________________ 3. When did Drs. Watson and Crick and Wilkins receive the Nobel Prize in P ...
Mutation and cancer
Mutation and cancer

... • DNA RNA protein • Mutated DNA mutated RNA mutated protein • Many mutations accumulated over time can result in harmful changes in the cells instructions • These mutations in genes result in mutations in proteins that control the cell ...
Lecture
Lecture

...  1.045 billion bases sequenced  1800 microbial species estimated to exist in sample, ...
3.4 DNA Replication - hrsbstaff.ednet.ns.ca
3.4 DNA Replication - hrsbstaff.ednet.ns.ca

... The unzipped strands of DNA now act as templates to build the new complementary strands.  Free floating nucleotides that are found inside the nucleus form complementary hydrogen bonds with the nucleotides in both of the DNA parent strands.  The nucleotides are also forming covalent bonds as the su ...
biochemical composition presentation
biochemical composition presentation

... • structure - materials for building cells • function a. carry substances throughout the body, in & out of cells b. trigger muscle movements c. assist with all chemical reactions in the body d. protect the body against disease ...
FAQ of Module 7
FAQ of Module 7

Clone
Clone

... What if you don't have enough DNA for colony hybridization or Southern blots? ...
Gene Expression Jeopardy
Gene Expression Jeopardy

... What is lactose? Sugar in milk ...
The Story of Molecular Biology and Its Creators
The Story of Molecular Biology and Its Creators

... “Once information has passed into protein it cannot get out again”… Crick’s choice of the word “dogma” was not a call for blind faith in what was really a central hypothesis. According to Horace Judson in his book The Eighth Day of Creation, it was because Crick had it in his mind that “a dogma was ...
The Story of Molecular Biology and Its Creators
The Story of Molecular Biology and Its Creators

... “Once information has passed into protein it cannot get out again”… Crick’s choice of the word “dogma” was not a call for blind faith in what was really a central hypothesis. According to Horace Judson in his book The Eighth Day of Creation, it was because Crick had it in his mind that “a dogma was ...
Deoksyribozymes active in the presence of cadmium ions and at low
Deoksyribozymes active in the presence of cadmium ions and at low

... which may be needed to ensure the proper folding of the molecules into a catalytically active structure. Studies using directed mutagenesis have shown that the presence of a purine residue in position 12 of the catalytic core is essential for the catalytic activity. On the other hand, the nucleotide ...
Mutations
Mutations

... Note that inserting or deleting 3 bases in the DNA wouldn’t shift the reading frame, it just adds or removes an amino acid. ...
PowerPoint
PowerPoint

... The storage of genetic information in DNA, the use of an RNA intermediate that is read in three letter words, and the mechanism of protein synthesis are essentially the same in all ...
June-2015-Biology-Final-Exam-Review
June-2015-Biology-Final-Exam-Review

Nucleic acids
Nucleic acids

... History of The Double Helix of DNA • The structure of the double helix was found by Rosalind Franklin using X-ray crystallography and correctly interpreted by Watson & Crick in 1953 who also used Chargaff’s rule. • The bases are Hydrophobic and are in the Centre of the helix where complementary bas ...
Bacteria cells reproduce differently from other single celled
Bacteria cells reproduce differently from other single celled

... What have they accomplished through this project? a. They used a single cell from one organism to create an identical organism. b. They created a single pedigree for every genetic disorder. c. They created DNA synthetically in a laboratory. d. They identified the sequence of base pairs in human gene ...
DNA - eduBuzz.org
DNA - eduBuzz.org

... The function of DNA The genetic information contained within the DNA can be thought of as a list of genetic instructions that the cells uses to make proteins. Proteins are made from amino acids joined together into chains. There are 20 different types of amino acids and the differences between prote ...
Paradigm Shifts in Biomedical Research
Paradigm Shifts in Biomedical Research

... Animals and other eukaryotes ...
Streptavidin is a small bacterial protein that binds
Streptavidin is a small bacterial protein that binds

... treatments that make holes into the cells membranes without killing them. If the DNA has their own replication sequences and some gene (‘marker’) that allows the cells to survive under certain conditions, it can be maintained in the cells for many generations (as long as in the presence of such sele ...
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Deoxyribozyme



Deoxyribozymes, also called DNA enzymes, DNAzymes, or catalytic DNA, are DNA oligonucleotides that are capable of catalyzing specific chemical reactions, similar to the action of other biological enzymes, such as proteins or ribozymes (enzymes composed of RNA).However, in contrast to the abundance of protein enzymes in biological systems and the discovery of biological ribozymes in the 1980s,there are no known naturally occurring deoxyribozymes.Deoxyribozymes should not be confused with DNA aptamers which are oligonucleotides that selectively bind a target ligand, but do not catalyze a subsequent chemical reaction.With the exception of ribozymes, nucleic acid molecules within cells primarily serve as storage of genetic information due to its ability to form complementary base pairs, which allows for high-fidelity copying and transfer of genetic information. In contrast, nucleic acid molecules are more limited in their catalytic ability, in comparison to protein enzymes, to just three types of interactions: hydrogen bonding, pi stacking, and metal-ion coordination. This is due to the limited number of functional groups of the nucleic acid monomers: while proteins are built from up to twenty different amino acids with various functional groups, nucleic acids are built from just four chemically similar nucleobases. In addition, DNA lacks the 2'-hydroxyl group found in RNA which limits the catalytic competency of deoxyribozymes even in comparison to ribozymes.In addition to the inherent inferiority of DNA catalytic activity, the apparent lack of naturally occurring deoxyribozymes may also be due to the primarily double-stranded conformation of DNA in biological systems which would limit its physical flexibility and ability to form tertiary structures, and so would drastically limit the ability of double-stranded DNA to act as a catalyst; though there are a few known instances of biological single-stranded DNA such as multicopy single-stranded DNA (msDNA), certain viral genomes, and the replication fork formed during DNA replication. Further structural differences between DNA and RNA may also play a role in the lack of biological deoxyribozymes, such as the additional methyl group of the DNA base thymidine compared to the RNA base uracil or the tendency of DNA to adopt the B-form helix while RNA tends to adopt the A-form helix. However, it has also been shown that DNA can form structures that RNA cannot, which suggests that, though there are differences in structures that each can form, neither is inherently more or less catalytic due to their possible structural motifs.
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