• Study Resource
  • Explore Categories
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Microsatellite Repeat Variation Within the y1 Gene of Maize and
Microsatellite Repeat Variation Within the y1 Gene of Maize and

... were found to exhibit the type 3d organization of the pentanucleotide repeat with three (CCA) repeats, which was the least number of repeats observed. However, another accession of Z perennis (i.e., Ames 21875) exhibited type 3c organization of the pentanucleotide repeat containing six (CCA) repeats ...
3rd Lecture
3rd Lecture

... incomplete combustion of fossil fuels and vegetable matter (including tobacco), and they are common environmental contaminants.  The PAHs are chemically inert, and require metabolism to exert their biologic effects  This is a multi-step process, it involves the following: initial epoxidation (cyto ...
BIO450 Primer Design Tutorial
BIO450 Primer Design Tutorial

... PCR is capable of amplifying a single target DNA fragment out of a complex mixture of DNA, if the sequence contains enough unique elements. Identifying the unique elements is the first step in primer design for target specificity. Of course, you might want to amplify a family of genes, in which case ...
EvolutionChapter11
EvolutionChapter11

... • Selection for small size results in selection of red balls • By chance, natural selection can lead to selection for correlated traits • Selection always acts for a particular phenotypic trait, but results in selection of the genes that code for this trait ...
8 DNA GENETIC TESTING - Centre for Genetics Education
8 DNA GENETIC TESTING - Centre for Genetics Education

... Finding that a person has a variation in a gene involved in a particular condition does not always relate to how a person is, or will be, affected by that condition. There may be modifying factors (other genes, environmental factors) that can affect the expression of the message from the gene. This ...
Slide 1
Slide 1

... oils have almost all cis bonds, but using oil for frying causes some of the cis bonds to convert to trans bonds. If oil is used only once like when you fry an egg, only a few of the bonds do this so it’s not too bad. However, if oil is constantly reused, like in fast food French fry machines, more a ...
PTC Genetics Lab Student Worksheet
PTC Genetics Lab Student Worksheet

... Electrophoresis is a technique used in many areas of science to analyze and separate samples by applying a constant electric field. Biologists or forensic scientists can use this technology to separate mixtures of DNA or dyes into each component based on size and electrical charge. The gel in gel el ...
Motif Finding Problem
Motif Finding Problem

... Drosophila DNase I Footprint Database (v2.0) http://www.flyreg.org/ ...
Minimally Invasive Human Bone - European Anthropological
Minimally Invasive Human Bone - European Anthropological

A novel human cytochrome P4S0 gene (P450IIB): chromosomal
A novel human cytochrome P4S0 gene (P450IIB): chromosomal

... human P450IIB gene has been located to chromosome 19ql2 > 19ql3.2 using a probe derived from intron 5, and is close to the CYP 2A locus encoding cytochrome P450IIA2. Restriction fragment length polymorphisms have been found with the enzymes fiamHI and which will enable linkage to be determined betwe ...
Answer Key Chapter 13
Answer Key Chapter 13

... house. There are no other members of this species in the pond. Which mechanism is this? This is an example of the founder effect, which is a type of genetic drift. 4. It is possible for mutation, genetic drift, and gene flow to cause microevolution. However, only chance by a(n) ____________ ev ...
Document
Document

... Suggestion Four: Evolution suggests regulatory changes (new uses of old ideas and methods) are at least as productive as structural changes (new ideas and new methods). Shortly, we will examine some potentially useful tools from evolutionary biology that may be of some use to livestock researchers. ...
Product Information FluoroVueTM Nucleic Acid Gel Stain (10,000X
Product Information FluoroVueTM Nucleic Acid Gel Stain (10,000X

... [TAE (40 mM Tris-acetate, 1 mM EDTA, pH 8) or TBE (89 mM Tris base, 89 mM boric acid, 1 mM EDTA, pH 8)] *For Agarose gel: Cool the molten agarose gel until it can be handled by hand. **Note: For optimal staining, protect the gel from light.  The casted gel with FluoroVueTM Nucleic Acid Gel Stain wi ...
Final Exam Practice
Final Exam Practice

... You PCR amplify the 1000 bp region affected by the mutation from individuals 1, 2, and 9, digest the PCR products with NheI or PvuII, and analyze the restriction fragments on a gel: ...
Chapter 14 - Richsingiser.com
Chapter 14 - Richsingiser.com

... sway, and whole domains move as a unit • Enzymes depend on such motions to provoke and direct catalytic events • Protein motions support catalysis in several ways. Active site conformation changes can: • Assist substrate binding • Bring catalytic groups into position • Induce formation of NACs • Ass ...
Review for Final
Review for Final

... Chapters: 5 – 19 (you may have a 3x5 card to use on the final) Chap 5 1) Sketch the structure of a saccharide (be able to identify a hexose, ribose, poly,…), lipid, & aminoacid. 2) What are the polysaccharides cellulose, glycogen, and starch used for? 3) What makes each of the 20 amino acids unique? ...
Table of Contents: Introduction
Table of Contents: Introduction

... comparison to neighboring world regions using autosomal STR data. In particular, this analysis will explore evidence for early migrations to Europe from West Asia (including Anatolia and the East Mediterranean) and Siberia (including early relatives of Native Americans). The background section highl ...
CS 2427 - Algorithms in Molecular Biology Lecture #2: 13 January
CS 2427 - Algorithms in Molecular Biology Lecture #2: 13 January

... The endpoint of each edge in a bidirected string graph can be thought of as either entering or leaving a node. The Hamiltonian Path problem for bidirected graphs is similar to the standard Hamiltonian Path problem with two particularities that are worth mentioning: firstly, one does not have to foll ...
Foundations of Biology - Geoscience Research Institute
Foundations of Biology - Geoscience Research Institute

... 5’AGUC-AUG-ACU-UGU-GGU-AGU-UGA-CUAGAAA3’ ...
Exam 2
Exam 2

... Lucilia cuprina, the sheep blowfly, lays its eggs in wounds and the wet fleece of sheep. The larvae hatch and burrow into the sheep’s skin, causing distress, reduced wool production and sometimes death. Particular chemicals were used in the past to control the L. cuprina but these became less effect ...
Recessive mutations
Recessive mutations

... Characteristics of Mutations at the DNA Level • Expanding Trinucleotide Repeats – may arise as a result of formation of hairpin structures during DNA replication – could also be due to unequal crossing over when repeated regions do not align properly ...
PGLO Transformation LAB AP LAB 7
PGLO Transformation LAB AP LAB 7

... Source of “glowing gene” for this experiment ...
EnzymesLect1 2014
EnzymesLect1 2014

... Enzyme activity can be affected by other molecules: a. Inhibitors are naturally occurring or synthetic molecules that decrease or abolish enzyme activity; b. activators are molecules that increase activity. Certain RNAs also have catalytic activity, but to differentiate them from protein enzymes, th ...
No Slide Title
No Slide Title

... cAMP-CAP helps RNA polymerase bind to promoter by interacting with the alpha subunit More in chapter II of Part Four ...
P1 The genetic code
P1 The genetic code

... • Despite the fact that they all carry out the same reaction of joining an amino acid to a tRNA, the various synthetase enzymes can be quite different. • They fall into one of four classes of subunit structure, being either a, a2, a4, a2b2. • The polypeptide chains range from 334 to over 1000 amino ...
< 1 ... 216 217 218 219 220 221 222 223 224 ... 1026 >

Deoxyribozyme



Deoxyribozymes, also called DNA enzymes, DNAzymes, or catalytic DNA, are DNA oligonucleotides that are capable of catalyzing specific chemical reactions, similar to the action of other biological enzymes, such as proteins or ribozymes (enzymes composed of RNA).However, in contrast to the abundance of protein enzymes in biological systems and the discovery of biological ribozymes in the 1980s,there are no known naturally occurring deoxyribozymes.Deoxyribozymes should not be confused with DNA aptamers which are oligonucleotides that selectively bind a target ligand, but do not catalyze a subsequent chemical reaction.With the exception of ribozymes, nucleic acid molecules within cells primarily serve as storage of genetic information due to its ability to form complementary base pairs, which allows for high-fidelity copying and transfer of genetic information. In contrast, nucleic acid molecules are more limited in their catalytic ability, in comparison to protein enzymes, to just three types of interactions: hydrogen bonding, pi stacking, and metal-ion coordination. This is due to the limited number of functional groups of the nucleic acid monomers: while proteins are built from up to twenty different amino acids with various functional groups, nucleic acids are built from just four chemically similar nucleobases. In addition, DNA lacks the 2'-hydroxyl group found in RNA which limits the catalytic competency of deoxyribozymes even in comparison to ribozymes.In addition to the inherent inferiority of DNA catalytic activity, the apparent lack of naturally occurring deoxyribozymes may also be due to the primarily double-stranded conformation of DNA in biological systems which would limit its physical flexibility and ability to form tertiary structures, and so would drastically limit the ability of double-stranded DNA to act as a catalyst; though there are a few known instances of biological single-stranded DNA such as multicopy single-stranded DNA (msDNA), certain viral genomes, and the replication fork formed during DNA replication. Further structural differences between DNA and RNA may also play a role in the lack of biological deoxyribozymes, such as the additional methyl group of the DNA base thymidine compared to the RNA base uracil or the tendency of DNA to adopt the B-form helix while RNA tends to adopt the A-form helix. However, it has also been shown that DNA can form structures that RNA cannot, which suggests that, though there are differences in structures that each can form, neither is inherently more or less catalytic due to their possible structural motifs.
  • studyres.com © 2026
  • DMCA
  • Privacy
  • Terms
  • Report