• Study Resource
  • Explore Categories
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Document
Document

... chromosome (original F insertion can occur at any one of many sites within chromosome) • direction/orientation of the F factor within that Hfr strain (clockwise or counter-clockwise) Mapping using different Hfr strains can provide a map of the entire bacterial chromosome ...
2017 Reg of Mitosis Genetics Protein Synth Regulation Review
2017 Reg of Mitosis Genetics Protein Synth Regulation Review

... purpose and place of DNA attachment. Be able to explain the purpose of enhancers, silencers, activators, repressors, DNA bending proteins and your close personal friend RNA polymerase II. Make sure you know how to say TATA correctly or else it will freak out even your bestest of friends! Be able to ...
Chapter 15 - Wesleyan College Faculty
Chapter 15 - Wesleyan College Faculty

... All stages of meiosis (Fig 13.7 useful) Different types of life cycles (basic, from fig 13.6) Independent assortment, crossing over (and how and where crossing over occurs) and random fertilization – what they are, how they are significant Chapter 14 Gregor Mendel Character, trait, true breeding, P1 ...
Unit 1.1 Building Blocks of Life The student knows the significance of
Unit 1.1 Building Blocks of Life The student knows the significance of

... occur in living organisms. The student is expected to: ...
21_Lecture_Presentation_PC
21_Lecture_Presentation_PC

... • The first evidence for mobile DNA segments came from geneticist Barbara McClintock’s breeding experiments with Indian corn • McClintock identified changes in the color of corn kernels that made sense only by postulating that some genetic elements move from other genome locations into the genes for ...
Prokaryotic Gene Regulation (PowerPoint) Gulf Coast 2012
Prokaryotic Gene Regulation (PowerPoint) Gulf Coast 2012

... 1. Use this process with transcription early in the semester using similar props 2. Add the rest of the chromosome (or on separate slide) 3. Teach termAnalogy in one lecture and send them home with home work 4. Next lecture shall be modeling (Tidbit #2) 5. (optional) Embedded clicker questions betwe ...
the three dynamic levels of dna consciousness
the three dynamic levels of dna consciousness

... rearrangements that can often have effects on the physical expression of a cell or organism (phenotypic). This change in complexity is simply not achievable by classic point mutations. However, TEs can induce these degrees of complexity by affecting the expression of nearby genes, which can be accom ...
Cloning and sequencing of glutamate mutase component E from
Cloning and sequencing of glutamate mutase component E from

... excluded. For such a mechanism it would be necessary that at least one subunit was synthesized as a precursor molecule and was post-translationally modified via a rearrangement involving an anhydro-serine. Based on the assumption that the reaction mechanism for all three vitamin B 12-dependent mutas ...
Enzymes are Most Effective at Optimal Conditions
Enzymes are Most Effective at Optimal Conditions

... WU: Enzymes are Most Effective at Optimal Conditions ...
Laboratory Projects
Laboratory Projects

... Repair mutants (rad1, rad52 and Yku70), rad9 checkpoint and mt based motility mutants (dynein, kip3, kar9) ...
No Slide Title
No Slide Title

... Relationship of mRNA to genomic DNA for RBP4 ...
Hypercholesterolemia
Hypercholesterolemia

... then adds nucleotides to the primers to complete each new complimentary strand of the target. These three steps constitute one PCR “cycle”. This process is typically repeated from 25-40 cycles, amplifying the target exponentially (Figure 4). PCR is performed in a thermal cycler, which is programmed ...
as a PDF
as a PDF

... they are not endowed with a primitive molecular genetic apparatus, nor do they appear to be more rudimentary in their metabolic abilities than their aerobic counterparts. Primitive living systems would initially refer to pre-RNA worlds, in which life may have been based on polymers using backbones o ...
Stabilizing, directional, and diversifying selection either
Stabilizing, directional, and diversifying selection either

... Sometimes natural selection can select for two or more distinct phenotypes that each have their advantages. In these cases, the intermediate phenotypes are often less fit than their extreme counterparts. Known as diversifying or disruptive selection, this is seen in many populations of animals that  ...
Chapter 8 Introduction to Enzymes and Metabolism
Chapter 8 Introduction to Enzymes and Metabolism

... enzyme’s active site. Most if the other amino acids comprising an enzyme can be mutated or changed (through DNA mutations) without effecting the enzyme’s biological activity (what it does). The few amino acids that comprise the active site, however, are critical to the enzyme’s biological activity, ...
protein
protein

... • Sickle-cell disease, an inherited blood disorder, results from a single amino acid substitution in the protein hemoglobin ...
Nerve activates contraction
Nerve activates contraction

... Enzyme structure changes upon binding of substrate Enzyme structure is flexiblecurrently accepted model. Enzyme binds substrate loosely, transition state tightly ...
Application of a Real Time Polymerase Chain Reaction Method to
Application of a Real Time Polymerase Chain Reaction Method to

The Importance of Epigenetic Phenomena in Regulating Activity of
The Importance of Epigenetic Phenomena in Regulating Activity of

... do not alter the nucleotide sequence of DNA. It can be described as a phenomenon that determines the final functionality of a locus or chromosome without changing the underlying DNA sequence (Goldberg, Allis, and Bernstein 2007). Instead of altering the DNA sequence, epigenetic factors affect how an ...
Genome-based bioprospecting of microbes for new
Genome-based bioprospecting of microbes for new

... genomic snapshots allowing detection of antibiotic biosynthesis genes. This has been followed by manipulation of media and growth conditions leading to expression of cryptic gene clusters, and production of potentially novel enediynes [2]. Recent advances in DNA sequencing made the ‘genomic snapsho ...
Mutations Notes
Mutations Notes

... ________________________________________________________________________ ...
A fast PCR assay to identify Meloidogyne hapla, M
A fast PCR assay to identify Meloidogyne hapla, M

013368718X_CH04_047
013368718X_CH04_047

... made during replication. Environmental conditions may increase the rate of mutation. Mutagens are chemical or physical agents in the environment that cause mutations. The effects of mutations on genes vary widely:  Some mutations have little or no effect.  Some mutations produce beneficial variati ...
A cofactor is a non-protein chemical compound that is
A cofactor is a non-protein chemical compound that is

... Metabolism involves a vast array of chemical reactions, but most fall under a few basic types of reactions that involve the transfer of functional groups. This common chemistry allows cells to use a small set of metabolic intermediates to carry chemical groups between different reactions. These grou ...
Instructions fro BLAST Alignment of sequences
Instructions fro BLAST Alignment of sequences

... 45. Are your answers to Question #44 the same as your answers from your DNA analysis (Part I, Question #24)? Is this what you would expect? Why or why not? 46. Record your results from the protein BLAST alignment by capturing an image from your computer and saving it in your BLAST Results Document f ...
< 1 ... 209 210 211 212 213 214 215 216 217 ... 1026 >

Deoxyribozyme



Deoxyribozymes, also called DNA enzymes, DNAzymes, or catalytic DNA, are DNA oligonucleotides that are capable of catalyzing specific chemical reactions, similar to the action of other biological enzymes, such as proteins or ribozymes (enzymes composed of RNA).However, in contrast to the abundance of protein enzymes in biological systems and the discovery of biological ribozymes in the 1980s,there are no known naturally occurring deoxyribozymes.Deoxyribozymes should not be confused with DNA aptamers which are oligonucleotides that selectively bind a target ligand, but do not catalyze a subsequent chemical reaction.With the exception of ribozymes, nucleic acid molecules within cells primarily serve as storage of genetic information due to its ability to form complementary base pairs, which allows for high-fidelity copying and transfer of genetic information. In contrast, nucleic acid molecules are more limited in their catalytic ability, in comparison to protein enzymes, to just three types of interactions: hydrogen bonding, pi stacking, and metal-ion coordination. This is due to the limited number of functional groups of the nucleic acid monomers: while proteins are built from up to twenty different amino acids with various functional groups, nucleic acids are built from just four chemically similar nucleobases. In addition, DNA lacks the 2'-hydroxyl group found in RNA which limits the catalytic competency of deoxyribozymes even in comparison to ribozymes.In addition to the inherent inferiority of DNA catalytic activity, the apparent lack of naturally occurring deoxyribozymes may also be due to the primarily double-stranded conformation of DNA in biological systems which would limit its physical flexibility and ability to form tertiary structures, and so would drastically limit the ability of double-stranded DNA to act as a catalyst; though there are a few known instances of biological single-stranded DNA such as multicopy single-stranded DNA (msDNA), certain viral genomes, and the replication fork formed during DNA replication. Further structural differences between DNA and RNA may also play a role in the lack of biological deoxyribozymes, such as the additional methyl group of the DNA base thymidine compared to the RNA base uracil or the tendency of DNA to adopt the B-form helix while RNA tends to adopt the A-form helix. However, it has also been shown that DNA can form structures that RNA cannot, which suggests that, though there are differences in structures that each can form, neither is inherently more or less catalytic due to their possible structural motifs.
  • studyres.com © 2026
  • DMCA
  • Privacy
  • Terms
  • Report