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insulinoma
insulinoma

...  Steroids (such as prednisone)—initial medical treatment if diet alone is ineffective; begin with low dosage and gradually increase as signs of low blood sugar (hypoglycemia) recur  Diazoxide (Proglycem®)—added after diet and steroids have proven ineffective  Streptozocin—a nitrosourea that selec ...
Pituitary Disease
Pituitary Disease

... • FALSE- it it used for central diabetes insipidus where the production of ADH is deficient • In nephrogenic DI, ADH levels are normal, but there is a defect in kidney tubules that interferes with water reabsorption ...
Diabetes Mellitus: Introduction
Diabetes Mellitus: Introduction

... Trigger event: transition from glucose intolerance to frank diabetes are often increased insulin requirements, i.e infections or puberty. A “Honeymoon" phase : glycemic control by modest doses of insulin or, rarely, insulin is not needed. However, residual beta cells disappear as the autoimmune proc ...
DIABETES-AISLING
DIABETES-AISLING

...  Psychology (NB in teenage years)  Tailor insulin therapy and delivery methods to each patient / family  Screen for complications  Transition to adult care – smooth ...
Assessment and Management of Patients with Diabetes Mellitus
Assessment and Management of Patients with Diabetes Mellitus

... Elevated BUN, creatinine and hct r/t dehydration Medical Management of DKA Rehydrate with normal saline, then follow with .45% NaCl then D5.45NS (or other) Restore electrolytes ECGs Hourly blood sugars IV insulin ...
Assessment and Management of Patients with Diabetes Mellitus
Assessment and Management of Patients with Diabetes Mellitus

... Elevated BUN, creatinine and hct r/t dehydration ...
Primary Care: An Ever Changing Landscape
Primary Care: An Ever Changing Landscape

... exams yearly, bladder dysfunction screening, bowel dysfunction screening, HTN and ACVD ...
Ch. 27-Drugs Used to Treat Diabetes and Thyroid Disease
Ch. 27-Drugs Used to Treat Diabetes and Thyroid Disease

... Insulin is given parenterally- by subcutaneous or intravenous injection. Because you do NOT give parenteral dose forms, you do NOT give insulin. Should a nurse delegate the administration of such to you, you must: -Refuse the delegation. Make sure to explain why. Do NOT just ignore the request. Make ...
Hyperlipaemia in Donkeys
Hyperlipaemia in Donkeys

... The condition of hyperlipaemia is defined by elevated plasma triglycerides (TG), potentially leading to the fatty infiltration of organs and subsequent organ failure. This elevation in plasma triglycerides is a consequence of a series of events, arising during periods of negative energy balance (whi ...
Equine Metabolic Syndrome (EMS) Testing
Equine Metabolic Syndrome (EMS) Testing

... Sample Collection and Processing Guidelines for Insulin, OST, Leptin and Thyroid Testing 1. Collect blood into a plain* red-top collection tube for serum or a lavender-top (EDTA) for plasma. 2. For plasma, gently invert the lavender-top blood tube several times immediately after collection to mix an ...
Introduction to homeostasis
Introduction to homeostasis

... example, blood sugar levels tend to rise after a meal and then to fall lower as glucose is assimilated under the control of insulin. Normally, fluctuations are kept within 70 to 110 mg cm−3. In type 1 diabetes cells in the pancreas stop making insulin. Consequently, blood glucose levels rise, causin ...
Type 2 diabetes mellitus treated with
Type 2 diabetes mellitus treated with

... • Exact role of SMBG in Type 2 diabetics not on insulin less clear and widely debated • Volume & cost of Rx for monitoring rising • SMBG should be available to people receiving sulphonylurea and prandial glucose regulators • Access to SMBG based on individual assessment • Arbitrary withdrawal of SMB ...
Transplantable Organs - Donate Life California
Transplantable Organs - Donate Life California

... Transplantable Organs Pancreas • The pancreas produces insulin, a hormone that helps the body use glucose (sugar) for energy, and enzymes that break down fat, protein and carbohydrates during digestion. • The pancreas controls the level of glucose in the blood. It is often transplanted with a kidney ...
Medical Environmental Behavioral Emergency Unit Vocabulary
Medical Environmental Behavioral Emergency Unit Vocabulary

... Behavioral emergency-situation in which a person  exhibits abnormal behavior that is unacceptable or intolerable to the patient, family, or community Positional asphyxia- is a form of asphyxia which ...
Diabetes: Cell‐in‐a‐Box for insulin producing cells
Diabetes: Cell‐in‐a‐Box for insulin producing cells

... or nanotechnological approaches are under investigation for the treatment of type I diabetes. In one proposed case, implanted stores of insulin are released by a rapid response valve sensitive to blood glucose levels. At least two approaches have been demonstrated in vitro. These closed‐ loop insuli ...
Clinical Trial To Test Safety of Stem Cell-Derived Therapy
Clinical Trial To Test Safety of Stem Cell-Derived Therapy

... that all medical treatments may present. “This is not yet a cure for diabetes,” said Henry. “The hope, nonetheless, is that this approach will ultimately transform the way individuals with Type 1 diabetes manage their disease by providing an alternative source of insulin-producing cells, potentially ...
Type 1 Diabetes Mellitus (Immune Mediated)
Type 1 Diabetes Mellitus (Immune Mediated)

... Nonfasting blood glucose greater than 200 mg/dL (11.1 mmol/L) with typical symptoms is diagnostic with or without ketonuria ...
Endocrine System
Endocrine System

... 1. Bruce is 8 ft tall weighs 260 lbs. Which endocrine glands may be responsible for his size? ...
Diabetic Care Plan 70-130 mg/dL other____________
Diabetic Care Plan 70-130 mg/dL other____________

... By signing below I understand that I am giving my permission to share this information with school staff/trained personnel as needed with strict confidentiality maintained by all. I also give my permission for the school nurse/aide to contact the Primary Care Physician or Endocrinologist if further ...
Diabetes mellitus (DM), also known as simply diabetes, is a group of
Diabetes mellitus (DM), also known as simply diabetes, is a group of

... • Type 2 DM begins with insulin resistance, a condition in which cells fail to respond to insulin properly. As the disease progresses a lack of insulin may also develop. This form was previously referred to as "non insulindependent diabetes mellitus" (NIDDM) or "adult-onset diabetes". The primary c ...
DIABETES and Heart Disease
DIABETES and Heart Disease

... Dr Hassan Makki DO FACC Phoenix Heart Center ...
Endocrine and Hematologic Emergencies
Endocrine and Hematologic Emergencies

... Type 2 patients produce inadequate amounts of insulin, or normal amount that does not function effectively. ...
ACP Level 2 Lesson Six
ACP Level 2 Lesson Six

... around 20 to one. This is mainly because T4 has a far longer half-life (the time it takes for the chemical to break down) than T3. T4 and T3 are mainly, but not exclusively concerned with metabolism and so if there is a deficiency you are likely to see weight gain and conversely if there is an exces ...
Topics1
Topics1

... • Amylin analogue: symlin • Amylin is a hormone secreted by the pancreatic beta cells in response to hyperglycemia, the main mechanism of amylin is to inhibit gastric emptying and to a lesser extent, suppression of glucagon ...
Q1. (a) Technicians in a hospital laboratory tested urine and blood
Q1. (a) Technicians in a hospital laboratory tested urine and blood

... The girl who took part in this investigation was being successfully treated with insulin. The graph shows that on some occasions, the concentration of glucose in her blood was very high. Suggest why. ...
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Artificial pancreas



The artificial pancreas is a technology in development to help people with diabetes automatically control their blood glucose level by providing the substitute endocrine functionality of a healthy pancreas.There are several important exocrine (digestive) and endocrine (hormonal) functions of the pancreas, but it is the lack of insulin production which is the motivation to develop a substitute. While the current state of insulin replacement therapy is appreciated for its life-saving capability, the task of manually managing the blood sugar level with insulin alone is arduous and inadequate.The goal of the artificial pancreas is two-fold:to improve insulin replacement therapy until glycemic control is practically normal as evident by the avoidance of the complications of hyperglycemia, and to ease the burden of therapy for the insulin-dependent.Different approaches under consideration include: the medical equipment approach—using an insulin pump under closed loop control using real-time data from a continuous blood glucose sensor. the bioengineering approach—the development of a bio-artificial pancreas consisting of a biocompatible sheet of encapsulated beta cells. When surgically implanted, the islet sheet will behave as the endocrine pancreas and will be viable for years. the gene therapy approach—the therapeutic infection of a diabetic person by a genetically engineered virus which causes a DNA change of intestinal cells to become insulin-producing cells.
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