Presentation (PowerPoint File) - IPAM
... The Problem of PE and PPE Proteins in M. tb PE, PE-PGRS, and PPE Proteins in M. tuberculosis ...
... The Problem of PE and PPE Proteins in M. tb PE, PE-PGRS, and PPE Proteins in M. tuberculosis ...
Prediction of mitochondrial proteins of malaria parasite
... them from mammalian mitochondria. Mitochondrial proteins of PF are different than human mitochondrial proteins; this makes PF mitochondrial protein as attractive potential drug targets (Vaidya and Mather 2009; Mather and Vaidya 2008; Vaidya and Mather 2005). Thus prediction of mitochondrial proteins ...
... them from mammalian mitochondria. Mitochondrial proteins of PF are different than human mitochondrial proteins; this makes PF mitochondrial protein as attractive potential drug targets (Vaidya and Mather 2009; Mather and Vaidya 2008; Vaidya and Mather 2005). Thus prediction of mitochondrial proteins ...
What are L-Amino Acids
... acids they require to live. This is in contrast to many animals (including humans) that are only able to manufacture certain amino acids, and must ingest the others in order to function. All amino acids that occur in proteins are of the “L” form (as opposed to “D” form). Essentially, these are mirro ...
... acids they require to live. This is in contrast to many animals (including humans) that are only able to manufacture certain amino acids, and must ingest the others in order to function. All amino acids that occur in proteins are of the “L” form (as opposed to “D” form). Essentially, these are mirro ...
Towards an Analysis of the Rice Mitochondrial Proteome
... 1996; Werhahn and Braun, 2002). A different solution to the exclusion problem, with an even wider applicability, is non-gel-based separation of complex mixtures. These approaches often use liquid chromatography (LC)-based separations of peptide derived from whole-sample digests that are directly cou ...
... 1996; Werhahn and Braun, 2002). A different solution to the exclusion problem, with an even wider applicability, is non-gel-based separation of complex mixtures. These approaches often use liquid chromatography (LC)-based separations of peptide derived from whole-sample digests that are directly cou ...
Control and Integration of Metabolism
... Deficiency of vitamins: Niacin, Thiamine, Panthothenic acid, Riboflavin, result in decrease oxidation of Acetyl CoA and ↑ formation of lactic acid ...
... Deficiency of vitamins: Niacin, Thiamine, Panthothenic acid, Riboflavin, result in decrease oxidation of Acetyl CoA and ↑ formation of lactic acid ...
Interpretation of bafilomycin, pH neutralizing or protease inhibitor
... Autophagy ensures the autophagosomemediated transport of cytoplasmic material to lysosomes for degradation and re-use. By now it has become widely accepted that analyzing the number of autophagy-related structures alone is an inadequate measure of autophagic degradation activity (flux), as increased ...
... Autophagy ensures the autophagosomemediated transport of cytoplasmic material to lysosomes for degradation and re-use. By now it has become widely accepted that analyzing the number of autophagy-related structures alone is an inadequate measure of autophagic degradation activity (flux), as increased ...
Instructions for Biochemistry
... life’s ultimate building blocks, called amino acids. The 20 different amino acids provide 20 diverse building blocks to make proteins. A gene, made of DNA, is chiefly a code to make the proteins that are critical in almost every function of our cells. After the DNA is transcribed into RNA, cellular ...
... life’s ultimate building blocks, called amino acids. The 20 different amino acids provide 20 diverse building blocks to make proteins. A gene, made of DNA, is chiefly a code to make the proteins that are critical in almost every function of our cells. After the DNA is transcribed into RNA, cellular ...
CH. 12.3 : DNA, RNA, and Protein
... The Genetic Code The nucleotide sequence transcribed from DNA to a strand of messenger RNA acts as a genetic message, the complete information for the building of a protein. Virtually all organisms share the same genetic code. ...
... The Genetic Code The nucleotide sequence transcribed from DNA to a strand of messenger RNA acts as a genetic message, the complete information for the building of a protein. Virtually all organisms share the same genetic code. ...
The biological meaning of pairwise alignments
... • What is the biological question? Examples: • Which proteins of the database are similar to my protein sequence? • Which proteins of the database are similar to the conceptual translation of my DNA sequence? • Which nucleotide sequences in the database are similar to my nucleotide sequence? • Which ...
... • What is the biological question? Examples: • Which proteins of the database are similar to my protein sequence? • Which proteins of the database are similar to the conceptual translation of my DNA sequence? • Which nucleotide sequences in the database are similar to my nucleotide sequence? • Which ...
Validating the Location of Fluorescent Protein
... to one isoform, for example, through use of synthetic peptide antigens. These antibodies may then be used to determine the endogenous localization of one isoform in cells that also express the FPF to another isoform, which acts as an internal control. This will also control for changes to FPF locali ...
... to one isoform, for example, through use of synthetic peptide antigens. These antibodies may then be used to determine the endogenous localization of one isoform in cells that also express the FPF to another isoform, which acts as an internal control. This will also control for changes to FPF locali ...
Amino Acids, Peptides, and Proteins
... appears to be a magic number with respect to peptide/protein structure. Oligopeptides with 20 or fewer amino acids do not fold into a “single” low energy conformation, rather they exist in numerous random shapes. Molecules with greater than 20 amino acids most often fold into a single stable low ene ...
... appears to be a magic number with respect to peptide/protein structure. Oligopeptides with 20 or fewer amino acids do not fold into a “single” low energy conformation, rather they exist in numerous random shapes. Molecules with greater than 20 amino acids most often fold into a single stable low ene ...
Validating the Location of Fluorescent Protein
... to one isoform, for example, through use of synthetic peptide antigens. These antibodies may then be used to determine the endogenous localization of one isoform in cells that also express the FPF to another isoform, which acts as an internal control. This will also control for changes to FPF locali ...
... to one isoform, for example, through use of synthetic peptide antigens. These antibodies may then be used to determine the endogenous localization of one isoform in cells that also express the FPF to another isoform, which acts as an internal control. This will also control for changes to FPF locali ...
2015 department of medicine research day
... (32% energy from fat; 25% energy from sucrose)] diets. While GT polyphenols are absorbed rapidly in the small intestine, high molecular weight polyphenols from BT are not absorbed and reach the large intestine. GT and BT consumption lead to alterations of the intestinal microflora. Objective: This s ...
... (32% energy from fat; 25% energy from sucrose)] diets. While GT polyphenols are absorbed rapidly in the small intestine, high molecular weight polyphenols from BT are not absorbed and reach the large intestine. GT and BT consumption lead to alterations of the intestinal microflora. Objective: This s ...
2016 department of medicine research day
... (32% energy from fat; 25% energy from sucrose)] diets. While GT polyphenols are absorbed rapidly in the small intestine, high molecular weight polyphenols from BT are not absorbed and reach the large intestine. GT and BT consumption lead to alterations of the intestinal microflora. Objective: This s ...
... (32% energy from fat; 25% energy from sucrose)] diets. While GT polyphenols are absorbed rapidly in the small intestine, high molecular weight polyphenols from BT are not absorbed and reach the large intestine. GT and BT consumption lead to alterations of the intestinal microflora. Objective: This s ...
Hemoglobin and Cytochrome c
... Overall mutation rates seem to occur at a rate of 1/100 (million years). Neutral mutation rates are a fraction of this and vary with each nucleotide and each gene. Mutations that adversely affect the gene are (presumably) selected against. The number of mutations that may be tolerated varies among g ...
... Overall mutation rates seem to occur at a rate of 1/100 (million years). Neutral mutation rates are a fraction of this and vary with each nucleotide and each gene. Mutations that adversely affect the gene are (presumably) selected against. The number of mutations that may be tolerated varies among g ...
Chapter 2 The Chemistry of Life
... Carbon forms the backbone or basic structure of life’s molecules, because it is abundant and flexible. ...
... Carbon forms the backbone or basic structure of life’s molecules, because it is abundant and flexible. ...
Optimization of temperature-glycerol -pH conditions for fed
... This study was undertaken to determine the optimum pH, temperature and glycerol feed rate for the production of recombinant hookworm (Ancylostoma caninum) anticoagulant peptide (rAcAP-5) by Pichia pastoris using response surface methodology (RSM). A central composite design was used as an experiment ...
... This study was undertaken to determine the optimum pH, temperature and glycerol feed rate for the production of recombinant hookworm (Ancylostoma caninum) anticoagulant peptide (rAcAP-5) by Pichia pastoris using response surface methodology (RSM). A central composite design was used as an experiment ...
Fatty Acid Synthesis Chapter 28, Stryer Short Course
... problem: no LDL receptors in non-liver cells • HDLs are “good cholesterol” ...
... problem: no LDL receptors in non-liver cells • HDLs are “good cholesterol” ...
Surveying Protein Structure and Function Using Bis
... fluorescence when coordinated to simple dithiol ligands such as ethanedithiol (EDT), but became increasingly fluorescent when bound by the four thiols present within the linear sequence CCRECC. When this sequence was encoded at the N- or C-terminus of a protein expressed in mammalian cells, treatmen ...
... fluorescence when coordinated to simple dithiol ligands such as ethanedithiol (EDT), but became increasingly fluorescent when bound by the four thiols present within the linear sequence CCRECC. When this sequence was encoded at the N- or C-terminus of a protein expressed in mammalian cells, treatmen ...
CHAPTER 1 PATHOGENESIS OF GOUSIEKTE 1.1
... Actin is one of the most conserved eukaryotic proteins and actin isoforms show greater than 90 % overall sequence homology, except in their 18 N-terminal residues (Lessard, 1988). The main actin in the heart is α-actin. The thin filament proteins tropomyosin (TPM) and the globular Ca2+-binding tropo ...
... Actin is one of the most conserved eukaryotic proteins and actin isoforms show greater than 90 % overall sequence homology, except in their 18 N-terminal residues (Lessard, 1988). The main actin in the heart is α-actin. The thin filament proteins tropomyosin (TPM) and the globular Ca2+-binding tropo ...
2.3 Carbon-Based Molecules
... • Proteins are polymers of amino acid monomers. – Twenty different amino acids are used to build proteins in organisms. – Amino acids differ in side groups, or R groups. – Amino acids are linked by peptide bonds. ...
... • Proteins are polymers of amino acid monomers. – Twenty different amino acids are used to build proteins in organisms. – Amino acids differ in side groups, or R groups. – Amino acids are linked by peptide bonds. ...
Chapter 3 Powerpoint - Trimble County Schools
... – They can be sold as prescription drugs and used to treat certain diseases – They may also be abused with serious consequences, such as liver damage that can lead to cancer ...
... – They can be sold as prescription drugs and used to treat certain diseases – They may also be abused with serious consequences, such as liver damage that can lead to cancer ...
ANPS 020 Black 03-16
... INSULIN: TRIGGERING ITS RELEASE Increase in blood glucose (after a meal) result in glucose entry into beta cells via GLT2 Cellular glucose metabolism result in increased ATP Increase in ATP inhibit intracellular K+ efflux Increase in cellular K+ results in cell depolarization and calcium entry Incre ...
... INSULIN: TRIGGERING ITS RELEASE Increase in blood glucose (after a meal) result in glucose entry into beta cells via GLT2 Cellular glucose metabolism result in increased ATP Increase in ATP inhibit intracellular K+ efflux Increase in cellular K+ results in cell depolarization and calcium entry Incre ...
DNA/RNA
... – U (in RNA) will attach to a A (in DNA) • Try it! A piece of DNA reads: T A G C A T T C C G A U transcribe to mRNA:___________________________ ...
... – U (in RNA) will attach to a A (in DNA) • Try it! A piece of DNA reads: T A G C A T T C C G A U transcribe to mRNA:___________________________ ...
Proteolysis
Proteolysis is the breakdown of proteins into smaller polypeptides or amino acids. Uncatalysed, the hydrolysis of peptide bonds is extremely slow, taking hundreds of years. Proteolysis is typically catalysed by cellular enzymes called proteases, but may also occur by intra-molecular digestion. Low pH or high temperatures can also cause proteolysis non-enzymatically.Proteolysis in organisms serves many purposes; for example, digestive enzymes break down proteins in food to provide amino acids for the organism, while proteolytic processing of a polypeptide chain after its synthesis may be necessary for the production of an active protein. It is also important in the regulation of some physiological and cellular processes, as well as preventing the accumulation of unwanted or abnormal proteins in cells. Consequently, dis-regulation of proteolysis can cause diseases, and is used in some venoms to damage their prey.Proteolysis is important as an analytical tool for studying proteins in the laboratory, as well as industrially, for example in food processing and stain removal.