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Multiple Sequence Alignments and Sequence Profiles
Multiple Sequence Alignments and Sequence Profiles

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Poster
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... inhibit PTP1B inside cells. LZP25 avoids this issue by not having a formal negative charge, but instead a polar area of similar size to phosphate. Binding to the PTP1B active site pocket (sites Ser216, Ala217, Ile219, Gln262, Gln266), its bulky side groups then prevent a key loop in the enzyme activ ...
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... amino acids in cell culture (SILAC). Cells are cultured in a medium supplemented with a labeled amino acid (lysine or arginine containing 13C or 15N). After several passages, cells are pooled with control cells grown in a medium of naturally occurring amino acids. The pooled samples are digested and ...
Xanthomonas campestris
Xanthomonas campestris

... (Supporting Information Table 3). It was interesting to observe a lower diversity of the bacterial proteins identified in REU as well as a higher amount of plant proteins in this sample. Similar results were obtained by Villeth et al. [13] when analyzing Xcc recovered from the resistant plant (REU) ...
Vicia species belonging to the subgenus Cracca are
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... RC: 4. The language of the manuscript is too weak which needs to be edited by native language professional for grammatical and syntax errors. AA: The language has been now revised by some one familiar with english ...
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putative mineral-specific proteins synthesized by a

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... (ii) State the maximum number of amino acids coded for by this length of mRNA. ...
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... et al., 2001). All the compartments that have been characterized share three common features: (1) The ER-derived compartments accumulate a large amount of a single protein or only a few different proteins. (2) The protein components do not act within the compartments, even if they are functional pro ...
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... Differentiate between an endotoxin and an exotoxin as far as source, chemistry and type of molecule (protein, or polysaccharide/lipid). List and understand how examples from class work (e.g., cytotoxin, hemolysin, neurotoxin, enterotoxin, endotoxin). It is not necessary to know the particular detail ...
The Production, Purification, and Bioactivity of Recombinant Bovine
The Production, Purification, and Bioactivity of Recombinant Bovine

... M Tris-HCI buffer, pH 8.0, at - 2 0 C for 6 months. Activity was not significantly reduced by four cycles of freezing and thawing. Activity was also retained when the protein was stored at 4 C for 2 weeks, or exposed to acidic conditions (pH 2.0; 30 min). This stability along with ease of purificati ...
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No Slide Title

... decomposition resulting in generation of ammonium salts and ammonia as ...
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- Wiley Online Library

... clability are among the main reasons that have prompted the use of enzymes in industrial biocatalysis [2, 3]. All these particular properties displayed by enzymes are a consequence of their complex 3-D structure. In the native state, the polypeptide chain adopts such a conformation that the hydropho ...
Allied Biochemistry II - E
Allied Biochemistry II - E

... (1) proteins are denatured by the SDS (2) proteins have the same charge-to-mass ratio (3) smaller proteins migrate more rapidly through the gel (4) all of the above 26. Proteins can be visualized directly in gels by (1) staining them with the dye (2) using electron microscope only (3) measuring thei ...
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Proteolysis



Proteolysis is the breakdown of proteins into smaller polypeptides or amino acids. Uncatalysed, the hydrolysis of peptide bonds is extremely slow, taking hundreds of years. Proteolysis is typically catalysed by cellular enzymes called proteases, but may also occur by intra-molecular digestion. Low pH or high temperatures can also cause proteolysis non-enzymatically.Proteolysis in organisms serves many purposes; for example, digestive enzymes break down proteins in food to provide amino acids for the organism, while proteolytic processing of a polypeptide chain after its synthesis may be necessary for the production of an active protein. It is also important in the regulation of some physiological and cellular processes, as well as preventing the accumulation of unwanted or abnormal proteins in cells. Consequently, dis-regulation of proteolysis can cause diseases, and is used in some venoms to damage their prey.Proteolysis is important as an analytical tool for studying proteins in the laboratory, as well as industrially, for example in food processing and stain removal.
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