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O. Ugur Sezerman Sabanci University MDBF 34056 Orhanli
O. Ugur Sezerman Sabanci University MDBF 34056 Orhanli

... Cakici S., Sumengen S., Sezerman U., Balcısoy S., “DockPro: A VR-Based Tool for ProteinProtein Docking Problem”, International Journal of Virtual Reality, 2008. Yeniterzi S., Sezerman U. “EnzyMiner: automatic identification of protein level mutations and their impact on target enzymes from PubMed ab ...
Biochemistry/Scientific Method Test Review Guide
Biochemistry/Scientific Method Test Review Guide

... 2. What are the building blocks of a protein? 3. How many amino acids are there? 4. What elements do proteins contain? Nucleic Acids 1. What is the function of a nucleic acid? 2. What are 2 examples of nucleic acids? 3. What is the monomer of nucleic acids? 4. What are the three parts of the monomer ...
Part I - OCCC.edu
Part I - OCCC.edu

syllabus - option b(human biochemistry)
syllabus - option b(human biochemistry)

... The aim of this option is to give students an understanding of the chemistry of important molecules foundin the human body, and the need for a balanced and healthy diet. Although the role that these molecules play in the body should be appreciated, the emphasis is placed on their chemistry, and stud ...
An Investigation into Glycoproteins Associated with Rotaviral Infection
An Investigation into Glycoproteins Associated with Rotaviral Infection

... Rotaviruses have a very specific cell tropism, infecting only the mature enterocytes on the tip of the intestinal villi, which suggests the existence of a specific host cell receptor [3]. The cellular recognition site(s) for rotavirus are not clearly defined despite the efforts of several research g ...
LS1a Fall 09
LS1a Fall 09

ch-3-bio-molecules
ch-3-bio-molecules

... and function, the tremendous variety of organic molecules contributes to the diversity of structures within an individual organism and even individual cells The reason for this? ...
fiii Fli I`.,
fiii Fli I`.,

... Amino acids produced by digestion of dietary protein and during protein turnover in body cells become part of the body's amino acid pool. The amino acid pool is the total quantity of free amino acids present in tissue cells,plasma, and other bodyfluids. The amino acids of the amino acid pool are ava ...
Waistline Growth On High-carb Diets Linked To Liver Gene
Waistline Growth On High-carb Diets Linked To Liver Gene

... to proteins and lipids (although peptidoglycans have peptide parts, they are composed of mixtures of D- and L-amino acids, and lame poly-glycine). We had mentioned these molecules when we saw membranes and membrane proteins. Many proteins have oligosaccharides covalently attached to them. Depending ...
Review Problems #2 (Enzyme Review, Phosphatases
Review Problems #2 (Enzyme Review, Phosphatases

... similar. Draw this rearrangement (curly arrows please). 9) Leucine is derived from the same pathway that generates valine. What additional carbon source is used in this synthesis? The later stages of leucine’s biosynthetic pathway are similar to what other pathway? 10) Threonine is derived from what ...
Glutamate Synthase - Blue Valley Schools
Glutamate Synthase - Blue Valley Schools

Title of project: Combating Inheritable heart disease: Functional and
Title of project: Combating Inheritable heart disease: Functional and

... Mitochondrial adenine nucleotide carriers are polytopic proteins located in the inner mitochondrial membrane. They are essential for life as they are one of the main sources of ATP supply for the cell thanks to their ability to export matrix ATP, synthesised by the respiratory chain, and import cyto ...
2010 Exam with answers
2010 Exam with answers

Human Physiology
Human Physiology

... in a protein is defined by the sequence of a gene, which is encoded in the genetic code. • In general, the genetic code specifies 20 standard amino acids. ...
Proceeding - ETH Zürich
Proceeding - ETH Zürich

(3.1.1.5a) Nucleic Acids
(3.1.1.5a) Nucleic Acids

... To understand the importance of nucleic acids, you must first understand the importance of proteins. Proteins have to have a special shape in order to do their job. For example, proteins that serve as enzymes have to have their active site, the groove that the substrate fits in. That shape is determ ...
The Urea Cycle - LSU School of Medicine
The Urea Cycle - LSU School of Medicine

Tracking a putative novel category copper type 3 protein across
Tracking a putative novel category copper type 3 protein across

... Hcl-1 is a novel copper type 3 protein, different from prophenoloxidase, tyrosinase and hemocyanin. Hcl-1 is present in Planorbid snails and their egg masses but may be absent from the sister-taxa Physidae and Lymnaeidae. Discussion and Conclusions Hcl-1 may derive from hemocyanin through gene repur ...
A1981LC33100001
A1981LC33100001

... other globulins, intestinal and salivary zymogen granules, and the structural proteins of the myelin sheath in the PNS. By contrast, connective tissues contain relatively little tryptophan and are unstained. At the time, the method added a useful amino acid stain to back up those for tyrosine, cysti ...
Catalogue Number CTK-573 Synonyms HCNTF, CNTF, Ciliary
Catalogue Number CTK-573 Synonyms HCNTF, CNTF, Ciliary

... phenotype is not causally related to neurologic disease. In addition to the predominant monocistronic transcript originating from this locus, the gene is also co-transcribed with the upstream ZFP91 gene. Co-transcription from the two loci results in a transcript that contains a complete coding regio ...
Syllabus
Syllabus

... Complete genomic sequences of human, other mammals, and numerous other organisms are known for some time. From early on, comparisons or analyses of genomic sequences require aids of computer programming. After brief introductions to molecular biology for CS students and computer algorithms for biolo ...
Poster
Poster

... from mutations in multiple genes. One candidate gene is T. T protein, a transcription factor found in a variety of animals including humans, is essential for correct embryonic development and guides the development of bone and cartilage from embryonic mesodermal tissue. T protein accumulates in the ...
Mutated
Mutated

... different between 2 people • (0.1% difference means 99.9% identical) • We have about 3 billion nucleotides in all, so that means there are about 3 million nucleotide differences between 2 people ...
No Slide Title
No Slide Title

... Energy Terms and Results - van der Waals protein:ligand - hydrophobic effect (surface area dependent) - electrostatic interactions (continuum approach) - translational, rotational, vibrational degrees of freedom ...
1.Jeremy_Introduction_of_Protein_Simulation_and_Drug_Design
1.Jeremy_Introduction_of_Protein_Simulation_and_Drug_Design

... Energy Terms and Results - van der Waals protein:ligand - hydrophobic effect (surface area dependent) - electrostatic interactions (continuum approach) - translational, rotational, vibrational degrees of freedom ...
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Protein structure prediction



Protein structure prediction is the prediction of the three-dimensional structure of a protein from its amino acid sequence — that is, the prediction of its folding and its secondary, tertiary, and quaternary structure from its primary structure. Structure prediction is fundamentally different from the inverse problem of protein design. Protein structure prediction is one of the most important goals pursued by bioinformatics and theoretical chemistry; it is highly important in medicine (for example, in drug design) and biotechnology (for example, in the design of novel enzymes). Every two years, the performance of current methods is assessed in the CASP experiment (Critical Assessment of Techniques for Protein Structure Prediction). A continuous evaluation of protein structure prediction web servers is performed by the community project CAMEO3D.
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