Transcription Coactivator Family Proteins
... shown to be the TATA-box binding protein, TBP. Several additional transcription factor binding sites have been included and shown to reside upstream of the 2 basal elements and of the transcriptional start site. The location and order of the variously indicated transcription factor-binding sites is ...
... shown to be the TATA-box binding protein, TBP. Several additional transcription factor binding sites have been included and shown to reside upstream of the 2 basal elements and of the transcriptional start site. The location and order of the variously indicated transcription factor-binding sites is ...
insilico.mutagenesis.help.me.please
... promotors) of interest. Please provide a plain nucleotide sequence. All non-DNA characters (e.g. as in FASTA formatted sequences) will cause an error. The addition of flanking nucleotide sequences is only necessary if a complete saturation or sequence scan of your protein is intended. For example if ...
... promotors) of interest. Please provide a plain nucleotide sequence. All non-DNA characters (e.g. as in FASTA formatted sequences) will cause an error. The addition of flanking nucleotide sequences is only necessary if a complete saturation or sequence scan of your protein is intended. For example if ...
Genes and Codes - Peter Godfrey
... molecules bind to specific three-base sequences in the mRNA. So each triplet of bases in the mRNA is associated, via the chemical properties of tRNA, with a particular amino acid. The "genetic code" is, strictly speaking, the rule linking RNA base triplets with amino acids, and this interpretation ...
... molecules bind to specific three-base sequences in the mRNA. So each triplet of bases in the mRNA is associated, via the chemical properties of tRNA, with a particular amino acid. The "genetic code" is, strictly speaking, the rule linking RNA base triplets with amino acids, and this interpretation ...
Aminoaciduria
... i.e. finally give rise to ketone bodies Leucine& lysine are the only exclusively ketogenic amino acids & therefore cannot give rise to glucose ...
... i.e. finally give rise to ketone bodies Leucine& lysine are the only exclusively ketogenic amino acids & therefore cannot give rise to glucose ...
Introduction to RNA sequencing
... – Find a question that seems useful and ‘vote it up’ – Answer a question [optional] – Search for a topic area of interest and ask a question that has not already been asked [optional] ...
... – Find a question that seems useful and ‘vote it up’ – Answer a question [optional] – Search for a topic area of interest and ask a question that has not already been asked [optional] ...
CHAPTER 20 - AMINO ACID METABOLISM Introduction Amino acid
... internal pH of a lysosome is acidic (-5), and lysosomal proteases have optimal activities in this pH range. Presumably, the cell is protected from damage associated with accidental lysosomal leakage because their enzymes have much lower activities at higher cellular pH values. Lysosomes also selecti ...
... internal pH of a lysosome is acidic (-5), and lysosomal proteases have optimal activities in this pH range. Presumably, the cell is protected from damage associated with accidental lysosomal leakage because their enzymes have much lower activities at higher cellular pH values. Lysosomes also selecti ...
1. Translation
... An additional control system is superimposed on the repressor operator system. This control system is thought to have evolved because the cell can capture more energy from the breakdown of glucose than it can from the breakdown of other sugars. If both lactose and glucose are present, the synthesis ...
... An additional control system is superimposed on the repressor operator system. This control system is thought to have evolved because the cell can capture more energy from the breakdown of glucose than it can from the breakdown of other sugars. If both lactose and glucose are present, the synthesis ...
Lecture 4 POWERPOINT here
... We learnt that there are 3 types of atomic interactions between atoms. ACTUALLY there are other forces too; van der Waals attractions weaker than hydrogen bonds attraction between closely located atoms Hydrophobic interactions weakest of all 3 dimensional structure of water forces hydrophobic groups ...
... We learnt that there are 3 types of atomic interactions between atoms. ACTUALLY there are other forces too; van der Waals attractions weaker than hydrogen bonds attraction between closely located atoms Hydrophobic interactions weakest of all 3 dimensional structure of water forces hydrophobic groups ...
DCA Metabolic Overview
... often referred to as B complex vitamins, also help the body use fats and protein. B complex vitamins are needed for healthy skin, hair, eyes, and liver. They also help the nervous system function properly. Folic acid is the synthetic form of B9, found in supplements and fortified foods, while folate ...
... often referred to as B complex vitamins, also help the body use fats and protein. B complex vitamins are needed for healthy skin, hair, eyes, and liver. They also help the nervous system function properly. Folic acid is the synthetic form of B9, found in supplements and fortified foods, while folate ...
DNA-dependent protein kinase in nonhomologous end joining: a
... crystals for crystalographic structure studies. The best available information on the three-dimensional structure of the DNA–Ku–DNA-PKCS heterotrimer was obtained by singleparticle electron microscopy at a 25-Å resolution (Spagnolo et al., 2006). These images clearly showed dimeric structures in whi ...
... crystals for crystalographic structure studies. The best available information on the three-dimensional structure of the DNA–Ku–DNA-PKCS heterotrimer was obtained by singleparticle electron microscopy at a 25-Å resolution (Spagnolo et al., 2006). These images clearly showed dimeric structures in whi ...
genetics: the code broken
... When the information in a gene is actually used to manufacture a particular polypeptide, we say it is being expressed. During the life of an organism, many genes are only expressed at certain times; during adolescence, for example, the genes responsible for the production of hormones will become ‘sw ...
... When the information in a gene is actually used to manufacture a particular polypeptide, we say it is being expressed. During the life of an organism, many genes are only expressed at certain times; during adolescence, for example, the genes responsible for the production of hormones will become ‘sw ...
Towards a Phylogeny of Bacteriophage via Protein Importance
... and I never felt confident in my mastery of the topic. In this respect, my REUT experience was most frustrating. Nevertheless, for my part, the summer was most satisfiying, and I might attribute my frustrations to occasional miscommunication or lack of communication on my part. At some point, the ga ...
... and I never felt confident in my mastery of the topic. In this respect, my REUT experience was most frustrating. Nevertheless, for my part, the summer was most satisfiying, and I might attribute my frustrations to occasional miscommunication or lack of communication on my part. At some point, the ga ...
Biology
... Key knowledge: Chemical nature of the cell Key skills: Aspects of all three areas • Investigate and inquire scientifically • Apply biological understanding and • Communicate biological information and understanding Biomacromolecules are made of many numbers of individual subunits. For example, prote ...
... Key knowledge: Chemical nature of the cell Key skills: Aspects of all three areas • Investigate and inquire scientifically • Apply biological understanding and • Communicate biological information and understanding Biomacromolecules are made of many numbers of individual subunits. For example, prote ...
Identification of a Novel Streptococcal Gene
... to ensure independent mutational events. DNA regions covering bases 228 to 255 and 293 to 314 from the parC gene were analyzed by pyrosequencing of ciprofloxacin-resistant wild-type (wt) and EH58 clones to determine the mutation frequency and mutation types present in the selected DNA region. ...
... to ensure independent mutational events. DNA regions covering bases 228 to 255 and 293 to 314 from the parC gene were analyzed by pyrosequencing of ciprofloxacin-resistant wild-type (wt) and EH58 clones to determine the mutation frequency and mutation types present in the selected DNA region. ...
TRANSPOSABLE GENETIC ELEMENTS
... a) Many bacterial transposons carry genes for generic antibiotic resistance. These genes typically produce enzymes that cleave and render antibiotics non-functional. Resistance is to several antibiotics within a class of antibiotic compounds, and differs from resistance conferred when cell metabolit ...
... a) Many bacterial transposons carry genes for generic antibiotic resistance. These genes typically produce enzymes that cleave and render antibiotics non-functional. Resistance is to several antibiotics within a class of antibiotic compounds, and differs from resistance conferred when cell metabolit ...
Exam 2 (pdf - 225.18kb)
... No marks will be given if more than one answer is completed for any question. ...
... No marks will be given if more than one answer is completed for any question. ...
Novel diagnostic parameters for AADC deficiency in general
... organic acids (see figure 1A). Because of the sometimes only small increase of VLA, and/or insufficient analytical sensitivity, AADC deficiency is probably seriously underdiagnosed. We present new findings in recently diagnosed patients that have yielded promising additional diagnostic parameters. ...
... organic acids (see figure 1A). Because of the sometimes only small increase of VLA, and/or insufficient analytical sensitivity, AADC deficiency is probably seriously underdiagnosed. We present new findings in recently diagnosed patients that have yielded promising additional diagnostic parameters. ...
Chapter 2 - Institut Montefiore
... These were originally discovered in 1868 by Friedrich Meischer (isolating DNA from pus cells on bandages). At that time, he could not confirm that nucleic acids might contain genetic information. DNA IS the genetic information of most living organisms. In contrast, some viruses (called retroviruse ...
... These were originally discovered in 1868 by Friedrich Meischer (isolating DNA from pus cells on bandages). At that time, he could not confirm that nucleic acids might contain genetic information. DNA IS the genetic information of most living organisms. In contrast, some viruses (called retroviruse ...
Creation/Evolution - Geoscience Research Institute
... representing a few amino acids or possibly one codon representing a “group” of amino acids More precise codon meaning evolves perhaps with only the first two bases having meaning with discrimination at the third position evolving later The code becomes “frozen” when the system becomes so complex tha ...
... representing a few amino acids or possibly one codon representing a “group” of amino acids More precise codon meaning evolves perhaps with only the first two bases having meaning with discrimination at the third position evolving later The code becomes “frozen” when the system becomes so complex tha ...
Reactions of I,I-Diacetoxyiodobenzene with Proteins: Conversion of
... no trace of this N-acylurea. Reaction rate studies with insulin and lysozyme also show that (1) is preferable to (2) for converting amide side-chains to amines (see Fig. 2). Although (2) reacts much faster than (1) with lysozyme at first, (1) introduces considerably more amino groups than (2) after ...
... no trace of this N-acylurea. Reaction rate studies with insulin and lysozyme also show that (1) is preferable to (2) for converting amide side-chains to amines (see Fig. 2). Although (2) reacts much faster than (1) with lysozyme at first, (1) introduces considerably more amino groups than (2) after ...
Nucleic acid analogue
Nucleic acid analogues are compounds which are analogous (structurally similar) to naturally occurring RNA and DNA, used in medicine and in molecular biology research.Nucleic acids are chains of nucleotides, which are composed of three parts: a phosphate backbone, a pucker-shaped pentose sugar, either ribose or deoxyribose, and one of four nucleobases.An analogue may have any of these altered. Typically the analogue nucleobases confer, among other things, different base pairing and base stacking properties. Examples include universal bases, which can pair with all four canonical bases, and phosphate-sugar backbone analogues such as PNA, which affect the properties of the chain (PNA can even form a triple helix).Nucleic acid analogues are also called Xeno Nucleic Acid and represent one of the main pillars of xenobiology, the design of new-to-nature forms of life based on alternative biochemistries.Artificial nucleic acids include peptide nucleic acid (PNA), Morpholino and locked nucleic acid (LNA), as well as glycol nucleic acid (GNA) and threose nucleic acid (TNA). Each of these is distinguished from naturally occurring DNA or RNA by changes to the backbone of the molecule.In May 2014, researchers announced that they had successfully introduced two new artificial nucleotides into bacterial DNA, and by including individual artificial nucleotides in the culture media, were able to passage the bacteria 24 times; they did not create mRNA or proteins able to use the artificial nucleotides. The artificial nucleotides featured 2 fused aromatic rings.