Extract from the Clinical Evaluation Report for adalimumab
... through Week 4) in which both groups received the appropriate induction dose were similar across treatment groups ranging from 12.1 to 15.5 μg/mL. This compares with a mean of approximately 12μg/mL in adults with CD given the same regimen. During the maintenance phase, the mean adalimumab trough con ...
... through Week 4) in which both groups received the appropriate induction dose were similar across treatment groups ranging from 12.1 to 15.5 μg/mL. This compares with a mean of approximately 12μg/mL in adults with CD given the same regimen. During the maintenance phase, the mean adalimumab trough con ...
Scientific Name: Trigonella foenum – graceum L
... The results indicate that the Trigonella foenum-graecum leaves extract possess antiinflammatory as well as antipyretic properties following both i.p. and p.o. administration. The possibility of alkaloids as antidiabeticcompounds, in this extract, is suggested (Ahmadiani et. al., , 2001).The extract ...
... The results indicate that the Trigonella foenum-graecum leaves extract possess antiinflammatory as well as antipyretic properties following both i.p. and p.o. administration. The possibility of alkaloids as antidiabeticcompounds, in this extract, is suggested (Ahmadiani et. al., , 2001).The extract ...
The Nuances of Hematological Oncology Clinical Trials
... The enormity of the naming and classification of hematologic cancers is apparent when examining a list of current studies on ClinicalTrials.gov, which offered within its category of “Cancer and Other Neoplasms,” some 473 available disease conditions in April 2014. A search on just leukemia reveals m ...
... The enormity of the naming and classification of hematologic cancers is apparent when examining a list of current studies on ClinicalTrials.gov, which offered within its category of “Cancer and Other Neoplasms,” some 473 available disease conditions in April 2014. A search on just leukemia reveals m ...
2 review of literature 28.06.2013
... Tinospora cordifolia (also known as Guduchi belongs to family Menispermaceae) has been reported to contain a polysaccharide as an immunomodulatory constituent in its crude stem extract (Desai et al., 2002) and was found to impart its effect as an adjuvant to augment process of ulcer healing, bacteri ...
... Tinospora cordifolia (also known as Guduchi belongs to family Menispermaceae) has been reported to contain a polysaccharide as an immunomodulatory constituent in its crude stem extract (Desai et al., 2002) and was found to impart its effect as an adjuvant to augment process of ulcer healing, bacteri ...
Adverse Drug Reaction Reports - Texas Department of State Health
... damage, QTc 510 msec, heart rate 96 bpm. He denied episodes of palpitations, syncope, or arrhythmias. He reported one episode of increased heart rate during this admission due to anxiety in which lorazepam was helpful. Scheduled medications at the time of abnormal EKG included lithium carbonate ER 3 ...
... damage, QTc 510 msec, heart rate 96 bpm. He denied episodes of palpitations, syncope, or arrhythmias. He reported one episode of increased heart rate during this admission due to anxiety in which lorazepam was helpful. Scheduled medications at the time of abnormal EKG included lithium carbonate ER 3 ...
Toxicology Introduct..
... male's larger blood volume and greater tissue mass which dilute the chemical. · For substances that are injected intramuscularly, lower blood levels can be expected with those drugs in individuals (usually men) with a greater muscle mass. · Also, drugs with a high lipid coefficient that normally par ...
... male's larger blood volume and greater tissue mass which dilute the chemical. · For substances that are injected intramuscularly, lower blood levels can be expected with those drugs in individuals (usually men) with a greater muscle mass. · Also, drugs with a high lipid coefficient that normally par ...
Anticholinergics for Overactive Bladder
... urine secondary to intra-abdominal pressure such as occurs with coughing, sneezing and exercise.9 • Anticholinergics (ACs) are useful drugs for treating OAB, however their use is limited by the side effects of dry mouth and constipation. ...
... urine secondary to intra-abdominal pressure such as occurs with coughing, sneezing and exercise.9 • Anticholinergics (ACs) are useful drugs for treating OAB, however their use is limited by the side effects of dry mouth and constipation. ...
recent advances in animal models of drug addiction
... these procedures, self-administration of a drug is incorporated into a multiple component schedule with other reinforcers. Studies using these procedures have shown that the contingencies for concurrent reinforcers can affect behavior asymmetrically and that the response requirement for reinforcers ...
... these procedures, self-administration of a drug is incorporated into a multiple component schedule with other reinforcers. Studies using these procedures have shown that the contingencies for concurrent reinforcers can affect behavior asymmetrically and that the response requirement for reinforcers ...
JETREA® Preparation and Administration
... which include the use of sterile gloves, a sterile drape and a sterile eyelid speculum (or equivalent). Adequate anesthesia and a broad spectrum microbiocide should be administered according to standard medical practice. The injection needle should be inserted 3.5 - 4.0 mm posterior to the limbus ai ...
... which include the use of sterile gloves, a sterile drape and a sterile eyelid speculum (or equivalent). Adequate anesthesia and a broad spectrum microbiocide should be administered according to standard medical practice. The injection needle should be inserted 3.5 - 4.0 mm posterior to the limbus ai ...
Evaluation of analgesic activity of Evodia lunu-ankenda
... Acute toxicity studies Acute toxicity studies were carried out on Swiss albino mice according to method proposed by Ghosh. Ethyl acetate extract at doses of 30, 100, 300, 1000 and 3000 mg/kg body weight were administrated to separate group of mice (n=6), after overnight fasting. Subsequent to admini ...
... Acute toxicity studies Acute toxicity studies were carried out on Swiss albino mice according to method proposed by Ghosh. Ethyl acetate extract at doses of 30, 100, 300, 1000 and 3000 mg/kg body weight were administrated to separate group of mice (n=6), after overnight fasting. Subsequent to admini ...
MELOXICAM Veterinary—Systemic
... on the basis of their potential clinical significance (reasons given in parentheses where appropriate)—not necessarily inclusive (» = major clinical significance). Except under special circumstances, this medication should not be used when the following medical problems exist: Bleeding disorders{R-3 ...
... on the basis of their potential clinical significance (reasons given in parentheses where appropriate)—not necessarily inclusive (» = major clinical significance). Except under special circumstances, this medication should not be used when the following medical problems exist: Bleeding disorders{R-3 ...
Product Monograph - AstraZeneca Canada
... In the case of acute or rapidly worsening dyspnea, a doctor should be consulted immediately. Increasing use of β2-agonists to control symptoms of bronchial obstruction, especially administration on a regular basis or in high amounts, indicates deterioration of asthma control. Under these conditions, ...
... In the case of acute or rapidly worsening dyspnea, a doctor should be consulted immediately. Increasing use of β2-agonists to control symptoms of bronchial obstruction, especially administration on a regular basis or in high amounts, indicates deterioration of asthma control. Under these conditions, ...
PHASE II DRUG METABOLISM: Glucuronidation and Sulfation
... β-methyldigoxin Terfenadine (withdrawn due to cardiotoxicity) Thioridazone Codeine Amitriptyline Diazepam Primidone Procainamide (A. Fura, Drug Discovery Today, 2006) ...
... β-methyldigoxin Terfenadine (withdrawn due to cardiotoxicity) Thioridazone Codeine Amitriptyline Diazepam Primidone Procainamide (A. Fura, Drug Discovery Today, 2006) ...
News Release Puma Biotechnology Reports First Quarter 2017
... Company believes that neratinib has clinical application in the treatment of several other cancers as well, including non-small cell lung cancer and other tumor types that over-express or have a mutation in HER2. Further information about Puma Biotechnology can be found at www.pumabiotechnology.com. ...
... Company believes that neratinib has clinical application in the treatment of several other cancers as well, including non-small cell lung cancer and other tumor types that over-express or have a mutation in HER2. Further information about Puma Biotechnology can be found at www.pumabiotechnology.com. ...
inspiolto - Boehringer Ingelheim (Canada)
... Data from a large, placebo-controlled US study that compared the safety of another longacting beta2-adrenergic agonist (salmeterol) to placebo added to patients’ usual asthma therapy, showed an increase in asthma-related deaths in patients receiving salmeterol. This finding with salmeterol is consid ...
... Data from a large, placebo-controlled US study that compared the safety of another longacting beta2-adrenergic agonist (salmeterol) to placebo added to patients’ usual asthma therapy, showed an increase in asthma-related deaths in patients receiving salmeterol. This finding with salmeterol is consid ...
ESSENTIAL PHARMACOTHERAPEUTICS To all those who believe in Humanity First Edition
... A17. It is a situation where there is minimal fluctuations in plasma levels of the drug following multiple administration. At the steady state the rate of drug entering the systemic circulation equals to the rate of elimination. Time to attain 95% of steady state = 4.3 x T½. Q18. What is Half-life ? ...
... A17. It is a situation where there is minimal fluctuations in plasma levels of the drug following multiple administration. At the steady state the rate of drug entering the systemic circulation equals to the rate of elimination. Time to attain 95% of steady state = 4.3 x T½. Q18. What is Half-life ? ...
BUSULFEX (BUSULFAN) INJECTION IS A POTENT CYTOTOXIC
... of the blood. All patients received 0.8 mg/kg BUSULFEX as a two-hour infusion every 6 hours for 16 doses over four days. Ninety percent (90%) of patients receiving this dose of BUSULFEX maintained AUCs less than 1,500 μMol-min which has generally been considered efficacious in terms of myelosuppres ...
... of the blood. All patients received 0.8 mg/kg BUSULFEX as a two-hour infusion every 6 hours for 16 doses over four days. Ninety percent (90%) of patients receiving this dose of BUSULFEX maintained AUCs less than 1,500 μMol-min which has generally been considered efficacious in terms of myelosuppres ...
A. Treating the outpatient with severe ulcerative colitis: case studies
... • Immunologic mechanisms for the protective effect of cigarette smoking in UC remain unclear • Immunologic and clinical studies in IBD have focused on nicotine • Therapeutic trial experience in UC with nicotine gum, ...
... • Immunologic mechanisms for the protective effect of cigarette smoking in UC remain unclear • Immunologic and clinical studies in IBD have focused on nicotine • Therapeutic trial experience in UC with nicotine gum, ...
Urinary Incontinence in Adults
... All products are listed in their generic groups. All products (not medication) listed are included in the National Nurses Prescribing Formulary. Products have been selected according to their efficiency, efficacy and availability. Current costs for each item can be obtained through the Drug Tariff. ...
... All products are listed in their generic groups. All products (not medication) listed are included in the National Nurses Prescribing Formulary. Products have been selected according to their efficiency, efficacy and availability. Current costs for each item can be obtained through the Drug Tariff. ...
coleus amboinicus lour. - Journal of Ayurveda and Holistic Medicine
... of bronchitis, asthma, diarrhoea, epilepsy, renal calculi & fever etc. Objectives: It is necessary to ascertain the authenticity of this drug when it is used for therapeutic purpose. Hence the present study was undertaken for systematic pharmacognostical evaluation of the leaves of Coleus amboinicus ...
... of bronchitis, asthma, diarrhoea, epilepsy, renal calculi & fever etc. Objectives: It is necessary to ascertain the authenticity of this drug when it is used for therapeutic purpose. Hence the present study was undertaken for systematic pharmacognostical evaluation of the leaves of Coleus amboinicus ...
AusPAR: Lipegfilgrastim - Therapeutic Goods Administration
... An Australian Public Assessment Report (AusPAR) provides information about the evaluation of a prescription medicine and the considerations that led the TGA to approve or not approve a prescription medicine submission. ...
... An Australian Public Assessment Report (AusPAR) provides information about the evaluation of a prescription medicine and the considerations that led the TGA to approve or not approve a prescription medicine submission. ...
Drug Development Pipeline
... nucleic acids or complex combinations of these substances, or may be living entities such as cells and tissues. Biologics are isolated from a variety of natural sources - human, animal, or microorganism - and may be produced by biotechnology methods and other cutting-edge technologies. Gene-based an ...
... nucleic acids or complex combinations of these substances, or may be living entities such as cells and tissues. Biologics are isolated from a variety of natural sources - human, animal, or microorganism - and may be produced by biotechnology methods and other cutting-edge technologies. Gene-based an ...
A New Approach to Drug Discovery and Development
... Chief Executive Officer and as a member of its board of directors since April 2006. Before Concert, Dr. Tung was a founding scientist at Vertex, a pharmaceutical company, where he was employed from 1989 to 2005 , most recently as its Vice President of Drug Discovery. Prior to Vertex, he held various p ...
... Chief Executive Officer and as a member of its board of directors since April 2006. Before Concert, Dr. Tung was a founding scientist at Vertex, a pharmaceutical company, where he was employed from 1989 to 2005 , most recently as its Vice President of Drug Discovery. Prior to Vertex, he held various p ...
3. Schizophrenia: subgroups and CB
... with an in vitro radioreceptor assay that quantifies the DA D2 receptor-blocking activity in serum in terms of haloperidol displacement from an aliquot of rat striatal tissue. The data from this assay correlate linearly with data obtained by chemical methods (e.g. high performance liquid chromatogra ...
... with an in vitro radioreceptor assay that quantifies the DA D2 receptor-blocking activity in serum in terms of haloperidol displacement from an aliquot of rat striatal tissue. The data from this assay correlate linearly with data obtained by chemical methods (e.g. high performance liquid chromatogra ...
Effect of pH on uptake and photodynamic action of chlorin p6 on
... pH levels.19 This may, in part, be responsible for the observation that the phototoxicity of chlorin p6 in MCF-7 cells did not show significant pH dependence. Sites of photodamage The sites where photodamage occurs within the cell depend on the subcellular localization of the photosensitizer, which i ...
... pH levels.19 This may, in part, be responsible for the observation that the phototoxicity of chlorin p6 in MCF-7 cells did not show significant pH dependence. Sites of photodamage The sites where photodamage occurs within the cell depend on the subcellular localization of the photosensitizer, which i ...