In cattle - Veterinary Medicines Directorate
... the treatment and control of the following species of gastro-intestinal roundworms, lungworms, eyeworms, warbles, mites and lice. Gastro-intestinal roundworms (adult and fourth-stage larvae): Ostertagia ostertagi (including inhibited O.ostertagi) ...
... the treatment and control of the following species of gastro-intestinal roundworms, lungworms, eyeworms, warbles, mites and lice. Gastro-intestinal roundworms (adult and fourth-stage larvae): Ostertagia ostertagi (including inhibited O.ostertagi) ...
The Effects of Nabilone on Sleep in Fibromyalgia: Results of a
... but not on wakefulness (difference ⫽ 0.3 [⫺0.2 to 0.8]). No effects on pain, mood, or quality of life were observed. AEs were mostly mild to moderate and were more frequent with nabilone. The most common AEs for nabilone were dizziness, nausea, and dry mouth. CONCLUSIONS: Nabilone is effective in im ...
... but not on wakefulness (difference ⫽ 0.3 [⫺0.2 to 0.8]). No effects on pain, mood, or quality of life were observed. AEs were mostly mild to moderate and were more frequent with nabilone. The most common AEs for nabilone were dizziness, nausea, and dry mouth. CONCLUSIONS: Nabilone is effective in im ...
Caspofungin: the first agent available in the echinocandin class of
... Caspofungin has not inhibited any cytochrome P450 isozyme in in vitro studies, nor has it inhibited the metabolism of CYP3A4 substrates in clinical studies. Caspofungin itself is not an in vitro substrate for P-glycoprotein and is a poor substrate for cytochrome P450 enzymes. Pharmacokinetic studies ...
... Caspofungin has not inhibited any cytochrome P450 isozyme in in vitro studies, nor has it inhibited the metabolism of CYP3A4 substrates in clinical studies. Caspofungin itself is not an in vitro substrate for P-glycoprotein and is a poor substrate for cytochrome P450 enzymes. Pharmacokinetic studies ...
QA253_3_AntidepressMisc_final
... There are no data relating to the passage of first generation MAOIs (tranylcypromine and phenelzine) into breast milk and no data to support their safe use in lactation. Other antidepressants are preferred in breastfeeding mothers (3). Unlike these drugs, moclobemide is a selective and reversible in ...
... There are no data relating to the passage of first generation MAOIs (tranylcypromine and phenelzine) into breast milk and no data to support their safe use in lactation. Other antidepressants are preferred in breastfeeding mothers (3). Unlike these drugs, moclobemide is a selective and reversible in ...
Anesthesia Related Drugs
... minutes, and the half‐life ranged from 51 to 90 minutes. Approximately 80 percent of the drug was eliminated in urine within 24 hours; approximately 50% as the unchanged drug, and 30 percent as metabolites. Following intravenous administration, plasma half‐life ranges from 47 to 60 minutes have be ...
... minutes, and the half‐life ranged from 51 to 90 minutes. Approximately 80 percent of the drug was eliminated in urine within 24 hours; approximately 50% as the unchanged drug, and 30 percent as metabolites. Following intravenous administration, plasma half‐life ranges from 47 to 60 minutes have be ...
Ramipril STADA tablet ENG SmPC
... Initial doses should be lower and subsequent dose titration should be more gradual because of greater chance of undesirable effects especially in very old and frail patients. A reduced initial dose of 1.25 mg ramipril should be considered. Paediatric population The safety and efficacy of ramipril in ...
... Initial doses should be lower and subsequent dose titration should be more gradual because of greater chance of undesirable effects especially in very old and frail patients. A reduced initial dose of 1.25 mg ramipril should be considered. Paediatric population The safety and efficacy of ramipril in ...
D I NEW DRUGS - Ontario Pharmacists Association
... randomized to one of the treatment groups, patients discontinued any previous antihypertensive medications and went through a single-blind placebo baseline phase for 1 to 4 weeks. If they qualified based on blood pressure measurements during the baseline phase, they were randomized to one of the dou ...
... randomized to one of the treatment groups, patients discontinued any previous antihypertensive medications and went through a single-blind placebo baseline phase for 1 to 4 weeks. If they qualified based on blood pressure measurements during the baseline phase, they were randomized to one of the dou ...
SPIRIVA® 18 microgram, inhalation powder, hard capsule
... significantly longer dissociation half-life than ipratropium. As an N-quaternary anticholinergic, tiotropium bromide is topically (broncho-) selective when administered by inhalation, demonstrating an acceptable therapeutic range before systemic anticholinergic effects may occur. Pharmacodynamic eff ...
... significantly longer dissociation half-life than ipratropium. As an N-quaternary anticholinergic, tiotropium bromide is topically (broncho-) selective when administered by inhalation, demonstrating an acceptable therapeutic range before systemic anticholinergic effects may occur. Pharmacodynamic eff ...
Guidelines for Use of Meperidine
... doses should be given more frequently. Studies have shown repeatedly that this is often not the case in clinical situations, where patients may have to endure recurrent pain unnecessarily. It is not well absorbed orally. Because the oral equianalgesic equivalent is three times the parenteral dose, p ...
... doses should be given more frequently. Studies have shown repeatedly that this is often not the case in clinical situations, where patients may have to endure recurrent pain unnecessarily. It is not well absorbed orally. Because the oral equianalgesic equivalent is three times the parenteral dose, p ...
The Effects of Betahistine and Dimenhydrinate on Caloric Test
... patients taking dimenhydrinate were advised to stop the drug immediately, as they did not have an attack of vertigo. These patients accepted having a caloric test done immediately with the added hope of less vestibular discomfort due to the test. The patients were informed that caloric tests measure ...
... patients taking dimenhydrinate were advised to stop the drug immediately, as they did not have an attack of vertigo. These patients accepted having a caloric test done immediately with the added hope of less vestibular discomfort due to the test. The patients were informed that caloric tests measure ...
Pre-Lab Questions
... paragraph describing whether you consider this to be ethical research? Include in your argument: Why is data collected on lab mice instead of humans? What other options do we have besides using mice? How closely do the results from testing on mice correlate with human LD50 values? Would it b ...
... paragraph describing whether you consider this to be ethical research? Include in your argument: Why is data collected on lab mice instead of humans? What other options do we have besides using mice? How closely do the results from testing on mice correlate with human LD50 values? Would it b ...
this Outline - Alcohol Medical Scholars Program
... 3’. Optimal dose varies; target is 80mg/day 4’. But MMT has drawbacks (Slide 26) a’’. Overdose common in early Rx b’’. Cannot be given from general practice office c’’. Strict gov’t control and paperwork for those clinics d’’. Stigma of daily clinic attendance c. Office-based buprenorphine Rx is nex ...
... 3’. Optimal dose varies; target is 80mg/day 4’. But MMT has drawbacks (Slide 26) a’’. Overdose common in early Rx b’’. Cannot be given from general practice office c’’. Strict gov’t control and paperwork for those clinics d’’. Stigma of daily clinic attendance c. Office-based buprenorphine Rx is nex ...
Hallucinogens - LSD, Peyote, Psilocybin, and PCP
... However, LSD does produce tolerance, so some users who take the drug repeatedly must take progressively higher doses to achieve the state of intoxication that they had previously achieved. This is an extremely dangerous practice, given the unpredictability of the drug. In addition, cross-tolerance b ...
... However, LSD does produce tolerance, so some users who take the drug repeatedly must take progressively higher doses to achieve the state of intoxication that they had previously achieved. This is an extremely dangerous practice, given the unpredictability of the drug. In addition, cross-tolerance b ...
The Effects of Modafinil Treatment on Neuropsychological and
... methamphetamine (MA) dependence were examined as part of a double-blind, randomized, placebo-controlled pilot trial. Recent evidence has identified modafinil-related improvements in treatment outcomes for MA-dependent patients; however, the benefits to cognition function, which is critical to treatm ...
... methamphetamine (MA) dependence were examined as part of a double-blind, randomized, placebo-controlled pilot trial. Recent evidence has identified modafinil-related improvements in treatment outcomes for MA-dependent patients; however, the benefits to cognition function, which is critical to treatm ...
NOVEL FAK-SELECTIVE INHIBITORS
... against FAK have been developed. The lead compound CTx0294945 displays drug-like physiochemical properties and is a highly selective orally bioavailable FAK inhibitor with excellent in vitro efficacy and modulation of a pharmacodynamic (PD) biomarker (FAK autophosphorylation, pY397), good in vitro A ...
... against FAK have been developed. The lead compound CTx0294945 displays drug-like physiochemical properties and is a highly selective orally bioavailable FAK inhibitor with excellent in vitro efficacy and modulation of a pharmacodynamic (PD) biomarker (FAK autophosphorylation, pY397), good in vitro A ...
... This rapid drug absorption is unfortunately also accompanied by a rapid decline in the drug levels in the systemic circulation. In the case of chronic conditions, daily or multiple weekly injections for years or even lifetime have resulted in poor patient compliance. For tissue regeneration therapy ...
(i) C1 inhibitor concentrates
... Medications are being developed to decrease adverse reactions (for example, avoiding viral contamination of blood products by using recombinant products) ...
... Medications are being developed to decrease adverse reactions (for example, avoiding viral contamination of blood products by using recombinant products) ...
(i) C1 inhibitor concentrates
... Medications are being developed to decrease adverse reactions (for example, avoiding viral contamination of blood products by using recombinant products) ...
... Medications are being developed to decrease adverse reactions (for example, avoiding viral contamination of blood products by using recombinant products) ...
enclosure-v
... hypertension. Its oral bioavilibility approximately around 25-35%, because of its first pass metabolism and half life is about 6-8 h, respectively. Carvedilol is a off-white crystaline powder. Melting point is 114 to 1150C. Carvedilol practically insoluble in water (0.583 mg/L).3 Hence, there is a n ...
... hypertension. Its oral bioavilibility approximately around 25-35%, because of its first pass metabolism and half life is about 6-8 h, respectively. Carvedilol is a off-white crystaline powder. Melting point is 114 to 1150C. Carvedilol practically insoluble in water (0.583 mg/L).3 Hence, there is a n ...
Drug Product Characterization: What Solid Form is in My Formulation?
... 20 hr data acquisition 10 % w/w LOD 0.8 % drug ...
... 20 hr data acquisition 10 % w/w LOD 0.8 % drug ...
Imprimir artigo
... expectancy, representing a considerable investment for institutions, which keep them in captivity. Further more these species are currently designated as threatened or endangered, demanding individual medical care (Pachaly et al., 2001). As in other wild species, rodent chemical restraint ...
... expectancy, representing a considerable investment for institutions, which keep them in captivity. Further more these species are currently designated as threatened or endangered, demanding individual medical care (Pachaly et al., 2001). As in other wild species, rodent chemical restraint ...
Deutsches Herzzentrum (Direktor: Univ.
... advanced among others by Andreas Grüntzig, who employed then newly developed inflatable balloon catheters that could dilate vascular stenosis.3 Endovascular therapy offers several distinct advantages over open surgical revascularization for selected lesions. It is performed with local anesthesia, wh ...
... advanced among others by Andreas Grüntzig, who employed then newly developed inflatable balloon catheters that could dilate vascular stenosis.3 Endovascular therapy offers several distinct advantages over open surgical revascularization for selected lesions. It is performed with local anesthesia, wh ...
Slide 1
... • Capsules, tablets and oral suspensions of amoxicillin may be given without regard to meals. The 400 mg suspension and the 875 mg tablet have been studies only when administered at the start of a light meal. However, food effect studies have not been performed with the 200mg and 500 mg formulations ...
... • Capsules, tablets and oral suspensions of amoxicillin may be given without regard to meals. The 400 mg suspension and the 875 mg tablet have been studies only when administered at the start of a light meal. However, food effect studies have not been performed with the 200mg and 500 mg formulations ...
Product Monograph - AstraZeneca Canada
... dialysis may be required as a means of reversing hypotension and/or substituting for impaired renal function; however, limited experience with those procedures has not been associated with significant clinical benefit. Candesartan cilexetil is not removed from plasma by dialysis. Animal data-Heart d ...
... dialysis may be required as a means of reversing hypotension and/or substituting for impaired renal function; however, limited experience with those procedures has not been associated with significant clinical benefit. Candesartan cilexetil is not removed from plasma by dialysis. Animal data-Heart d ...
Vasostrict - Par Sterile Products
... Safety and effectiveness of Vasostrict® in pediatric patients with vasodilatory shock have not been established. 8.5 Geriatric Use Clinical studies of vasopressin did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects. Oth ...
... Safety and effectiveness of Vasostrict® in pediatric patients with vasodilatory shock have not been established. 8.5 Geriatric Use Clinical studies of vasopressin did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects. Oth ...